New insight into praziquantel against various developmental stages of schistosomes.

Abstract:

:Praziquantel, due to high efficacy, excellent tolerability, few and transient side effects, simple administration, and competitive cost, is virtually the only drug of choice for treatment of human schistosomiasis. Treatment of schistosomiasis has shown great advances with the introduction of the drug into the therapeutic arsenal in areas that are endemic for the parasite. However, the drug presents various efficacies against different developmental stages of schistosomes, appearing an oddity intermitted mode. The present review article reviews the effects and mechanism of action of praziquantel against schistosomes briefly and suggests the research on this oddity phenomenon.

journal_name

Parasitol Res

journal_title

Parasitology research

authors

Wu W,Wang W,Huang YX

doi

10.1007/s00436-011-2670-3

subject

Has Abstract

pub_date

2011-12-01 00:00:00

pages

1501-7

issue

6

eissn

0932-0113

issn

1432-1955

journal_volume

109

pub_type

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