Abstract:
:Praziquantel, due to high efficacy, excellent tolerability, few and transient side effects, simple administration, and competitive cost, is virtually the only drug of choice for treatment of human schistosomiasis. Treatment of schistosomiasis has shown great advances with the introduction of the drug into the therapeutic arsenal in areas that are endemic for the parasite. However, the drug presents various efficacies against different developmental stages of schistosomes, appearing an oddity intermitted mode. The present review article reviews the effects and mechanism of action of praziquantel against schistosomes briefly and suggests the research on this oddity phenomenon.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Wu W,Wang W,Huang YXdoi
10.1007/s00436-011-2670-3subject
Has Abstractpub_date
2011-12-01 00:00:00pages
1501-7issue
6eissn
0932-0113issn
1432-1955journal_volume
109pub_type
杂志文章,评审abstract::This study is focused on the feasibility of two treatments of alcohol-fixed monogenean parasites which are intended to be use for the combined morphological and molecular characterizations. The monogenean parasite, Eudiplozoon nipponicum, was selected as a model parasite species; however it is expected that these tech...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-010-1949-0
更新日期:2010-09-01 00:00:00
abstract::The present study uses scanning and transmission electron microscopical observations to examine the haptoral features of the hexabothriid polyopisthocotylean monogenean Rajonchocotyle emarginata from the gills of the elasmobranch Amblyraja radiata. The haptor possesses six equal, pedunculate suckers, each armed with a...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-016-4973-x
更新日期:2016-06-01 00:00:00
abstract::We have identified the 2-Cys peroxiredoxin (Prx) from a bovine Babesia parasite, B. bovis. Prx is a recently described family of antioxidant enzymes that are highly conserved in eukaryotes and prokaryotes. B. bovis 2-Cys Prx (BbTPx-1) contained two conserved cysteine residues that corresponded to Cys47 and Cys170 of t...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-009-1587-6
更新日期:2009-10-01 00:00:00
abstract::Cryptosporidium spp. are common intestinal protozoa causing diarrhea in humans and a variety of animal species. With the recent development of fur industry, a large number of fur animals are farmed worldwide, especially in China. The existence of identical Cryptosporidium species/genotypes in humans and fur animals su...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-017-5686-5
更新日期:2018-01-01 00:00:00
abstract::A seasonal investigation on the occurrence of fishborne zoonotic trematodes (FZT) in economically important mono-cultured hybrid catfish and giant gouramy was conducted in the Mekong Delta of Vietnam. Fish from carp poly-culture and intensive small-scale integrated vegetable-aquaculture-animal husbandry farming (VAC) ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-007-0633-5
更新日期:2007-10-01 00:00:00
abstract::Nucleotide sequences of the triose phosphate isomerase (TPI) gene (624 bp) and mitochondrial cytochrome b (cob) gene (520 bp) were obtained by PCR and evaluated for utility in inferring the phylogenetic relationships among Trichuris species. Published sequences of one other nuclear gene (18S or SSU rRNA, 1816-1846 bp)...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-015-4705-7
更新日期:2015-12-01 00:00:00
abstract::The gypsy virus of Drosophila melanogaster is the first identified retrovirus of insects. Its infectious properties have been reported, and it is able to cause diverse mutations of the phenotype in the fruit fly. As a typical endogenous retrovirus, it is transmitted vertically as part of the host genome, but horizonta...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-006-0249-1
更新日期:2007-01-01 00:00:00
abstract::Saliva has been suggested as an easily accessible and a noninvasive diagnostic alternative for detection of antibodies. To identify and characterize Schistosoma japonicum (S. japonicum) antigens that are recognized by saliva of infected host, we have used a pool of saliva from infected patients to immunoscreen an egg ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-009-1575-x
更新日期:2009-10-01 00:00:00
abstract::Although the life cycle of the equid stomach parasite Habronema muscae was disclosed more than 100 years ago, little is known about the effect of the developing nematode larvae in its intermediate host, Musca domestica. In a series of experiments, freshly hatched M. domestica larvae were exposed to H. muscae eggs cont...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-016-5312-y
更新日期:2017-02-01 00:00:00
abstract::Increased gametocytemia in infections with resistant strains of Plasmodium species and their enhanced transmissibility are a matter of concern in planning and evaluating the impact of malaria control strategies. Various studies have determined weekly gametocyte carriage in response to antimalarial drugs in clinical tr...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-014-3789-9
更新日期:2014-04-01 00:00:00
abstract::Plasmodium berghei XAT is an irradiation-induced, permanent attenuated derivative from high-virulence P. berghei NK65. Monoclonal antibodies against XAT were developed. By immunofluorescence screening, one monoclonal antibody was identified that was reactive with XAT at the schizont stage but not with NK65 nor with an...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00535143
更新日期:1988-01-01 00:00:00
abstract::Severe and complicated malaria is usually caused by Plasmodium falciparum malaria (PF) but it has been increasingly observed that Plasmodium vivax malaria (PV), which was otherwise considered to be benign malaria, with a low case-fatality ratio, can also occasionally result in severe disease as with PF malaria. There ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-011-2776-7
更新日期:2012-06-01 00:00:00
abstract::Vector-borne diseases caused by mosquitoes are one of the major economic and health problems in many countries. The Aedes aegypti mosquito is a vector of several diseases in humans like yellow fever and dengue. Vector control methods involving the use of chemical insecticides are becoming less effective due to develop...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-014-3811-2
更新日期:2014-05-01 00:00:00
abstract::Mosquitoes are the major vector for the transmission of malaria, dengue fever, yellow fever, filariasis, schistosomiasis, and Japanese encephalitis. Mosquito control is facing a threat because of the emergence of resistance to synthetic insecticides. Insecticides of botanical origin may serve as suitable alternative b...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-013-3709-4
更新日期:2014-02-01 00:00:00
abstract::Toxoplasma gondii is a parasite which can be transmitted to humans via the consumption of contaminated meat products derived from different animal species, e.g., poultry. In Europe, the consumption rate of poultry meat is high and may pose a risk for humans. However, little is known about the prevalence and immune res...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-014-3788-x
更新日期:2014-04-01 00:00:00
abstract::Both the oncospheral tegument and the hook region membrane (HRM) of Echinococcus multilocularis hexacanths originate from a syncytial binucleate complex that appears in the early stage of morphogenesis and organogenesis of the hexacanth larva. The primordium of this binucleate complex forms a binucleate syncytial cap ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-018-5752-7
更新日期:2018-03-01 00:00:00
abstract::An optimized protocol is presented to visualize gene expression in the sedentary beet cyst nematode, Heterodera schachtii, by whole-mount in situ hybridization. Two different probes were used for genes with known expression pattern in other nematodes. Vacuum infiltration of the fixative significantly increased its eff...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-002-0661-0
更新日期:2002-08-01 00:00:00
abstract::Changes of serum cytokines including interferon gamma inducible protein-10 (IP-10) chemokine were analyzed in a total of eight vivax malarial patients before and after chemotherapy by immunostaining for human cytokine antibodies attached to membranes. IP-10 was strongly reactive in the period before chloroquine/primaq...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-006-0263-3
更新日期:2006-12-01 00:00:00
abstract::The structure modulation of follicular cells and the ovarian changes during fourth larval instar and pupal stage of the malaria vector mosquitoes Anopheles pharoensis Theobald were investigated using the light and electron microscopy. The generative organs consist of a pair of polytrophic ovaries (OV), which are oblon...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-014-4099-y
更新日期:2014-11-01 00:00:00
abstract::The Qinghai-Tibetan Plateau (QTP, in western China), which is the largest and highest plateau on Earth, is a highly epidemic region for Echinococcus spp. We collected 70 Echinococcus samples from humans, dogs, sheep, yaks, plateau pikas, and voles in eastern and southern Qinghai and genotyped them using the mitochondr...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-012-2815-z
更新日期:2012-07-01 00:00:00
abstract::Balamuthia mandrillaris is a free-living ameba and an opportunistic agent of lethal granulomatous amebic encephalitis (GAE) in humans and other mammals. Its supposed routes of infection have been largely assumed from what is known about Acanthamoeba spp. and Naegleria fowleri, other free-living amebae and opportunisti...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-004-1163-z
更新日期:2004-09-01 00:00:00
abstract::This paper reports the efficacy of a novel flavoured tablet formulation of emodepside plus praziquantel (Profender tablets for dogs) against mature and immature adult hookworms (Ancylostoma caninum and Uncinaria stenocephala) in dogs. The tablets were used at the minimum recommended dose of 1 mg emodepside and 5 mg pr...
journal_title:Parasitology research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00436-009-1490-1
更新日期:2009-08-01 00:00:00
abstract::Mosquito repellents represent a cleaner and safer alternative for population control and reduce the diseases they carry in large areas of the world. Recently, research has been focused on repellents of natural origins, both crude essential oils and their main constituents. We have observed that, although a large numbe...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-014-3827-7
更新日期:2014-05-01 00:00:00
abstract::The aim of the study is to understand the anti-Clonorchis sinensis properties of mebendazole and albendazole, and compare to praziquantel and tribendimidine. Two hundred and thirty rats were divided into five batches for experimental treatment. In four batches, each rat was infected orally with 50 or 100 C. sinensis m...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-010-2187-1
更新日期:2011-03-01 00:00:00
abstract::Blastocystis spp., one of the most common parasites colonizing the human intestine, is an extracellular, luminal protozoan with controversial pathogenesis. The host's immune response against Blastocystis spp. infection has also not been defined yet. Therefore, this research aimed to assess the potential pathogenicity ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-016-4951-3
更新日期:2016-05-01 00:00:00
abstract::Preliminary findings of a high prevalence of Clonorchis sinensis in wild-caught fish in a North Vietnam reservoir (Thac Ba reservoir, Yen Bai Province) prompted a longitudinal epidemiological study of fish infections. Monthly collections of fish from September 2014 to August 2015 were processed for recovery of metacer...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-016-5100-8
更新日期:2016-09-01 00:00:00
abstract::Eimeria spp. multiply within the intestinal tract causing severe inflammatory responses. Chitosan (CS), meanwhile, has been shown to exhibit anti-inflammatory activities in different experimental models. Here, we investigated the effect of CS on the outcome of inflammation caused by Eimeria papillata in the mouse inte...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-016-5035-0
更新日期:2016-07-01 00:00:00
abstract::This study assessed the anisakid nematode distribution pattern in the fish collected from coasts of Mediterranean Sea, Egypt, during the period September 2010-April 2011. Two hundred thirty out of 300 (76.7%) Dicentrarchus labrax (European seabass) marine fishes belonging to family Moronidae were dissected and found t...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-011-2600-4
更新日期:2012-03-01 00:00:00
abstract::Ticks and tick-borne diseases (TBDs) continue to pose an insidious and ever-present threat to livestock and livelihoods across the globe. Two of the most significant TBDs of cattle in Africa are heartwater and babesioisis, caused by Ehrlichia ruminantium and Babesia bigemina respectively. Both pathogens are endemic in...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-019-06204-1
更新日期:2019-03-01 00:00:00
abstract::Adult worms that belong to Carassotrema Park 1938 and Elonginurus Lu, 1955 were found in the intestine of Carassius gibelio Bloch, 1782 from the southern Russian Far East and Mugil cephalus Linnaeus, 1758 from northern Vietnam, respectively. Morphometric parameters, geographic location and host species composition of ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-019-06328-4
更新日期:2019-07-01 00:00:00