Efficacy of emodepside plus praziquantel tablets (Profender tablets for dogs) against mature and immature adult Ancylostoma caninum and Uncinaria stenocephala infections in dogs.

Abstract:

:This paper reports the efficacy of a novel flavoured tablet formulation of emodepside plus praziquantel (Profender tablets for dogs) against mature and immature adult hookworms (Ancylostoma caninum and Uncinaria stenocephala) in dogs. The tablets were used at the minimum recommended dose of 1 mg emodepside and 5 mg praziquantel per kg body weight. Four randomised, blinded and controlled laboratory studies demonstrated >95% efficacy against mature and immature adult stages of U. stenocephala and four randomised, blinded and controlled laboratory studies demonstrated >98% efficacy against mature and immature adult stages of A. caninum. No side effects of the treatment were observed. It is concluded that the emodepside plus praziquantel tablet is an effective and safe treatment against mature and immature hookworms.

journal_name

Parasitol Res

journal_title

Parasitology research

authors

Schimmel A,Altreuther G,Schroeder I,Charles S,Cruthers L,Ketzis J,Kok DJ,Kraemer F,McCall JW,Krieger KJ

doi

10.1007/s00436-009-1490-1

subject

Has Abstract

pub_date

2009-08-01 00:00:00

pages

S9-16

eissn

0932-0113

issn

1432-1955

journal_volume

105 Suppl 1

pub_type

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