Abstract:
:This paper reports the efficacy of a novel flavoured tablet formulation of emodepside plus praziquantel (Profender tablets for dogs) against mature and immature adult hookworms (Ancylostoma caninum and Uncinaria stenocephala) in dogs. The tablets were used at the minimum recommended dose of 1 mg emodepside and 5 mg praziquantel per kg body weight. Four randomised, blinded and controlled laboratory studies demonstrated >95% efficacy against mature and immature adult stages of U. stenocephala and four randomised, blinded and controlled laboratory studies demonstrated >98% efficacy against mature and immature adult stages of A. caninum. No side effects of the treatment were observed. It is concluded that the emodepside plus praziquantel tablet is an effective and safe treatment against mature and immature hookworms.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Schimmel A,Altreuther G,Schroeder I,Charles S,Cruthers L,Ketzis J,Kok DJ,Kraemer F,McCall JW,Krieger KJdoi
10.1007/s00436-009-1490-1subject
Has Abstractpub_date
2009-08-01 00:00:00pages
S9-16eissn
0932-0113issn
1432-1955journal_volume
105 Suppl 1pub_type
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