Ocular lesions in acute disseminated tuberculosis.

Abstract:

PURPOSE:To determine the prevalence of ocular involvement in patients with acute disseminated tuberculosis and to assess the findings associated with ocular involvement. METHODS:Assessment of all intensive care (ICU) admissions with a differential diagnosis of mycobacterial sepsis during a period of one year, with a detailed systemic and ophthalmic evaluation. RESULTS:Of 342 admissions, 24 patients were suspected to have mycobacterial infection. Of these 24 cases, 10 were proven to have mycobacterial sepsis, six of which (60%) showed evidence of ocular involvement. Five (83%) of the six patients had choroidal tubercles and one (16%) had retinal vasculitis. Detection of the lesions allowed a lead time of 12-72 hours in which to start earlier targeted therapy. CONCLUSIONS:Ocular involvement in acute disseminated tuberculosis is often seen, with the most common manifestation being choroidal tubercles. Early detection of these lesions may be important in treatment.

journal_name

Ocul Immunol Inflamm

authors

Mehta S

doi

10.1080/092739490500354

subject

Has Abstract

pub_date

2004-12-01 00:00:00

pages

311-5

issue

4

eissn

0927-3948

issn

1744-5078

pii

GFRFGRPL8C5QPMG8

journal_volume

12

pub_type

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