The spectrum of ocular involvement in systemic lupus erythematosus in a tertiary eye care center in Nepal.

Abstract:

PURPOSE:Manifestations of Systemic lupus erythematosus are protean and the eye can get affected in more than a third of the cases. This study was conducted to evaluate the spectrum of ocular manifestation among Nepalese patients diagnosed with Systemic lupus erythematosus. METHODS:In this hospital based cross-sectional study, 91 established cases of Systemic lupus erythematosus were enrolled from January 2008 to June 2009 AD. Patient particulars including age, sex, duration, systemic involvement, laboratory findings and treatment history were noted. Detailed ophthalmological examination was carried. RESULTS:Out of 91 patients, 94.5% were females and 5.5% were males. Female/Male ratio was 17:1. Mean age of the patients was 26.59 ± 10.33 years. Ocular involvement was present in 47.3% (43) of the patients, the commonest manifestation being dry eye (39.5%) followed by lupus retinopathy (21%) and drug induced ocular complications (21%). CONCLUSIONS:Ocular manifestations in Systemic lupus erythematosus are not uncommon.

journal_name

Ocul Immunol Inflamm

authors

Sitaula R,Shah DN,Singh D

doi

10.3109/09273948.2011.610023

subject

Has Abstract

pub_date

2011-12-01 00:00:00

pages

422-5

issue

6

eissn

0927-3948

issn

1744-5078

journal_volume

19

pub_type

杂志文章
  • Incidence and Risk Factors for Developing Glaucoma Among Patients with Uveitis in a University-based Tertiary Referral Center in Riyadh, Saudi Arabia.

    abstract:PURPOSE:To investigate the incidence and risk factors of secondary glaucoma among uveitis patients. METHODS:Retrospective review of medical records of 642 patients (1220 eyes). RESULTS:Glaucoma was diagnosed in 169 (13.9%) eyes and was most common in eyes with anterior uveitis (19.1%) (p < 0.001). HLA-B27-positive an...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2015.1047036

    authors: Al Rubaie K,Al Dhahri H,Al Fawaz A,Hemachandran S,Mousa A,Mohamed AG,Al-Obeidan SA,Abu El-Asrar AM

    更新日期:2016-10-01 00:00:00

  • Neuro-Ophthalmic Manifestations of HIV Infection.

    abstract::Purpose: To review the broad spectrum of clinical neuro-ophthalmic presentations associated with human immunodeficiency virus (HIV) infection. Methods: Critical review of the literature regarding neuro-ophthalmic consequences of HIV infection and its sequelae. Results: Neuro-ophthalmological diseases are common in bot...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1704024

    authors: Gordon LK,Danesh-Meyer H

    更新日期:2020-10-02 00:00:00

  • Atypical Syphilitic Outer Retinitis and Severe Retinal Vasculitis as Onset Manifestations in a Patient with Concurrent HIV and Syphilis Infection.

    abstract:INTRODUCTION:The most distinctive patterns of posterior pole affectation in syphilitic patients are acute posterior placoid chorioretinitis (ASPPC), pseudoretinitis pigmentosa and panuveitis with white focal preretinal opacities. However, outer retinitis is not a common presenting feature in this disease. CASE REPORT:...

    journal_title:Ocular immunology and inflammation

    pub_type: 信件

    doi:10.1080/09273948.2020.1787464

    authors: Vidal-Villegas B,Arcos-Villegas G,Fernández-Vigo JI,Díaz-Valle D

    更新日期:2020-07-23 00:00:00

  • Subcutaneous Tocilizumab for Cystoid Macular Edema Secondary to Juvenile Idiopathic Arthritis (JIA)-associated Uveitis: A Case Report.

    abstract::Purpose: To report a case of cystoid macular edema (CME) secondary to juvenile idiopathic arthritis (JIA)-associated uveitis. Case report: 26-year-old female patient presented with CME in both eyes. CME became refractory and TCZ-IV was initiated. After 12 infusions was stopped because grade 1 neuropenia developed. On ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1644350

    authors: Adán A,Moll-Udina A,Ramirez J,Llorenç V

    更新日期:2019-10-07 00:00:00

  • Clinical Profile, Ultra-Wide-Field Fluorescence Angiography Findings, and Long-Term Prognosis of Uveitis in Tubulointerstitial Nephritis and Uveitis Syndrome at One Tertiary Medical Institute in China.

    abstract::Purpose: To analyze the clinical features and long-term prognosis of uveitis in tubulointerstitial nephritis and uveitis (TINU) syndrome in a cohort of Chinese patients. Methods: A total of 32 patients with TINU syndrome between 2000 - 2016 were analyzed retrospectively. Results: Mild anterior inflammation was observe...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2017.1394469

    authors: Yang M,Chi Y,Guo C,Huang J,Yang L,Yang L

    更新日期:2019-01-01 00:00:00

  • Immunopathology of Virus-Induced Anterior Uveitis.

    abstract::Herpes simplex virus, varicella zoster virus, human cytomegalovirus, and rubella virus are the most common causes of virus-induced anterior uveitis. They can present in a variety of entities not only with typical but also overlapping clinical characteristics. These viral infections are commonly associated with ocular ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:10.1080/09273948.2018.1439069

    authors: De Groot-Mijnes JDF,Chan ASY,Chee SP,Verjans GMGM

    更新日期:2018-01-01 00:00:00

  • Immune deviation and ocular infections with varicella zoster virus.

    abstract::Since experimental, herpes simplex virus-induced acute retinal necrosis (ARN) develops in mice only if the mice fail to acquire virus-specific delayed hypersensitivity (DH) and despite their production of anti-viral antibodies (i.e. ACAID), I investigated whether a similar situation exists for patients with either var...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1076/ocii.12.1.17.28066

    authors: Kezuka T

    更新日期:2004-03-01 00:00:00

  • Innate Immunity Biomarkers for Early Detection of Keratoconus.

    abstract::Purpose: To compare toll-like receptors 2 (TLR2) and 4 (TLR4) expression in cells of corneal and conjunctival epithelium between unilateral KC patients and control subjects. Methods: Prospective cross-sectional case-control study, including 50 unilateral KC patients and 20 control subjects. TLR2 and TLR4 expression wa...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2018.1511813

    authors: Malfeito M,Regueiro U,Pérez-Mato M,Campos F,Sobrino T,Lema I

    更新日期:2019-01-01 00:00:00

  • Bacterial contamination of needles used for intravitreal injections: a prospective, multicenter study.

    abstract:PURPOSE:To determine the incidence of bacterial contamination of needles used for intravitreal injections. METHODS:Patients undergoing intravitreal injections were enrolled prospectively. No pre-injection antibiotics were administered. Following povidone-iodine irrigation, conjunctival cultures were taken and the inje...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,多中心研究

    doi:10.3109/09273948.2010.520405

    authors: Stewart JM,Srivastava SK,Fung AE,Mahmoud TH,Telander DG,Hariprasad SM,Ober MD,Mruthyunjaya P

    更新日期:2011-02-01 00:00:00

  • Does Pharmaceutical Compounding of Vascular Endothelial Growth Factor Inhibitors for Intravitreal Use Alter the Risk of Post-injection Endophthalmitis?

    abstract:PURPOSE:To investigate the safety of pharmaceutically compounded syringes for intravitreal administration of anti-vascular endothelial growth factor (anti-VEGF) drugs. METHODS:Single center, retrospective chart review. From 2015 to 2019, Oslo University Hospital, Norway gradually implemented pharmaceutical compounding...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2020.1820530

    authors: Blom K,Bragadóttir R,Sivertsen MS,Moe MC,Jørstad ØK

    更新日期:2020-10-07 00:00:00

  • Autoimmune retinopathy in a patient with autoimmune polyendocrine syndrome type I.

    abstract:PURPOSE:To present a case of autoimmune retinopathy resulting from a mutation in the autoimmune regulator (AIRE) gene. DESIGN:Case study. METHODS:Case review. RESULTS:Mild improvement of goldmann visual field following treatment with systemic and local immunosuppression. CONCLUSIONS:There are a limited number of ca...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2012.754906

    authors: Breunig A,Lee MS,Miller BS,Binstadt BA,Anderson MS,Montezuma S

    更新日期:2013-04-01 00:00:00

  • Long-term Efficacy of Interferon in Severe Uveitis Associated with Behçet Disease.

    abstract:PURPOSE:To retrospectively assess the frequency of ocular relapse and the possibility of long-term remission in patients treated with interferon (IFN) for severe uveitis associated with Behçet disease. METHODS:All patients were treated with an initial dosage of 3 million IU IFN three times a week. The main outcome mea...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2016.1206204

    authors: Diwo E,Gueudry J,Saadoun D,Weschler B,LeHoang P,Bodaghi B

    更新日期:2017-02-01 00:00:00

  • Drug therapy in Behçet's disease.

    abstract::Behçet's disease is one of the most difficult forms of uveitis to treat. Variety in disease presentation and severity, as well as regional differences in standard of care, demand a tailor-made approach. Anterior segment inflammation generally responds to topical corticosteroids. However, the onset of posterior segment...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:

    authors: Okada AA

    更新日期:2000-06-01 00:00:00

  • A comparison of heparin-coated and uncoated intraocular lenses in glaucoma patients undergoing combined cataract extraction and trabeculectomy and in diabetic patients undergoing cataract extraction.

    abstract::The postoperative course of cataract extraction and IOL implantation combined with trabeculectomy in glaucoma patients and of cataract extraction with intraocular lens (IOL) in diabetic patients is more complicated than that of cataract extraction with IOL implantation in otherwise healthy eyes. The main complications...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273949309057057

    authors: Zalish M,Rahmiel R,Pollack A,Milstein A,Oliver M

    更新日期:1993-01-01 00:00:00

  • Precise monitoring and differentiation of inflammatory events by indocyanine green (ICG) angiography in a case of recurrent posterior sarcoid uveitis.

    abstract:PURPOSE:By providing information on choroidal lesions, indocyanine green (ICG) angiography is complementary to fluorescein angiography in the workup of posterior uveitis. The aim here was to illustrate practically the suitability of performing dual fluorescein/ICG angiograms in a demonstrative case of recurrent presume...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1076/ocii.8.4.303.6458

    authors: Herbort CP

    更新日期:2000-12-01 00:00:00

  • Ocular Behçet's Disease: Changing Patterns Over Time, Complications and Long-Term Visual Prognosis.

    abstract:PURPOSE:To investigate demographic, clinical features and complications of Italian patients with ocular Behçet's disease (BD) over time. METHODS:Retrospective study of 385 patients examined from 1968 to 2011, 265 of whom had follow-up ≥ 12 months. RESULTS:A significant increase in the proportion of females (p = 0.03)...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2015.1094095

    authors: Accorinti M,Pesci FR,Pirraglia MP,Abicca I,Pivetti-Pezzi P

    更新日期:2017-02-01 00:00:00

  • Intravitreal Ranibizumab for the Treatment of Irvine-Gass Syndrome.

    abstract:PURPOSE:The purpose of our study was to evaluate the potential efficacy and safety of intravitreal ranibizumab in patients with pseudophakic cystoid macular edema (CME). METHODS:This retrospective study comprised 7 eyes with CME treated with intravitreal ranibizumab. Patients were examined at 1 week and 1 month after ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2014.898775

    authors: Mitropoulos PG,Chatziralli IP,Peponis VG,Drakos E,Parikakis EA

    更新日期:2015-06-01 00:00:00

  • A privileged view of NKT cells and peripheral tolerance through the eye.

    abstract::The eye is an immune-privileged site that uses specialized mechanisms to protect itself from damage and to preserve its visual acuity. Among the mechanisms that contribute to the eye's privileged existence is its ability to induce both local and peripheral tolerance to antigens that may transgress its chambers. Experi...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:10.1080/09273940490912371

    authors: Stein-Streilein J

    更新日期:2005-04-01 00:00:00

  • The Effect of Androgens on Proinflammatory Cytokine Secretion from Human Ocular Surface Epithelial Cells.

    abstract::Purpose: The purpose of this study is to explore the effects of dihydrotestosterone (DHT) on lipopolysaccharide (LPS)-induced proinflammatory cytokine release in human ocular surface epithelial cells exposed to LPS and LPS-binding protein (LBP).Methods: Immortalized human corneal, conjunctival, and meibomian gland epi...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1686155

    authors: Marangoz D,Oner C,Schicht M,Turgut Cosan D,Paulsen F,Yildiz E,Zibandeh N,Sahin A

    更新日期:2019-11-18 00:00:00

  • Atypical presentation of multiple evanescent white dot syndrome (MEWDS).

    abstract:PURPOSE:To present fundus autofluorescence (FAF), indocyanine green angiography (ICGA), and microperimetry (MP) findings of a patient with multiple evanescent white dot syndrome (MEWDS). METHODS:Observational case report. RESULTS:A 30-year-old woman with blurry vision was referred for evaluation. Fundus examination r...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940802026060

    authors: Yenerel NM,Kucumen B,Gorgun E,Dinc UA

    更新日期:2008-05-01 00:00:00

  • Epidemic Retinitis with Macular Edema -Treatment Outcome with and without Steroids.

    abstract::Purpose: To study treatment outcomes with and without oral corticosteroids in epidemic retinitis (ER).Method: A retrospective, observational study of 35 eyes of 29 patients diagnosed as ER. Days taken for resolution of macular edema and retinitis lesions were compared in patients treated with oral antibiotics (Group 1...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1704792

    authors: Kawali A,Srinivasan S,Mohan A,Bavaharan B,Mahendradas P,Shetty B

    更新日期:2020-01-21 00:00:00

  • Distinguishing Microvasculature Features of Vogt-Koyanagi-Harada in Patients in Acute and Convalescent Phases Using Optical Coherence Tomography Angiography.

    abstract::Purpose: To evaluate retinal and choroidal microvascular features of VKH patients in acute and convalescent phases after treatment using OCTA.Methods: A prospective, observational study was conducted in patients with initial VKH at the acute stage (n = 15) and healthy participants (n = 15) served as controls. After 3-...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1695856

    authors: Luo K,Cai H,Hu Y,Jin C,Gan X,Deng Y,Lu M,Chen H,Su L,Chen G,Chi W

    更新日期:2020-01-03 00:00:00

  • Whole-body 18FDG PET-CT imaging of systemic sarcoidosis: ophthalmic oncology and uveitis.

    abstract:PURPOSE:To describe whole-body 18-fluorodeoxyglucose (FDG) positron emission tomography/computed radiographic tomography (PET-CT) imaging of ophthalmic patients with systemic sarcoidosis. METHODS:Four systemic sarcoidosis patients were evaluated with PET-CT for staging. Two had been treated for conjunctival melanoma a...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940802596567

    authors: Shulman JP,Latkany P,Chin KJ,Finger PT

    更新日期:2009-03-01 00:00:00

  • Multimodal Imaging in Ocular Tuberculosis.

    abstract::Intraocular tuberculosis presents a diagnostic challenge because of its protean clinical manifestations. Thus, it becomes imperative to distinguish chorioretinal inflammation due to tuberculosis from other infectious as well as non-infectious posterior uveitis since the clinical manifestations of these entities may be...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:10.1080/09273948.2016.1231332

    authors: Agarwal A,Mahajan S,Khairallah M,Mahendradas P,Gupta A,Gupta V

    更新日期:2017-02-01 00:00:00

  • Stenotrophomonas maltophilia Endophthalmitis after cataract extraction.

    abstract:PURPOSE:To report the clinical course, treatment response, and prognosis of Stenotrophomonas maltophilia endophthalmitis following cataract extraction. METHODS:The clinical records of six cases of S. maltophilia endophthalmitis after cataract extraction were retrospectively reviewed. Data were collected for surgical c...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940590950981

    authors: Karakurt A,Abdik O,Sengün A,Karadağ R,Saricaoğlu S,Sarikatipoğlu HY,Hasiripi H

    更新日期:2006-02-01 00:00:00

  • Tocilizumab for the Treatment of Behçet Uveitis that Failed Interferon Alpha and Anti-Tumor Necrosis Factor-Alpha Therapy.

    abstract:PURPOSE:To report the results of tocilizumab (TCZ) treatment in patients with Behçet uveitis (BU) who had failed conventional, interferon alpha, and anti-Tumor necrosis factor-alpha therapy. METHODS:We reviewed the records of five patients with BU treated with monthly infusions of TCZ 8 mg/kg. Outcome measures were vi...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2017.1355471

    authors: Eser Ozturk H,Oray M,Tugal-Tutkun I

    更新日期:2018-01-01 00:00:00

  • HLA-B27 Anterior Uveitis: Immunology and Immunopathology.

    abstract::Acute anterior uveitis (AAU) is the commonest type of uveitis and HLA-B27 AAU is the most frequently recognized type of acute anterior uveitis and anterior uveitis overall. Recent evidence indicates that acute anterior uveitis is a heterogenous disease, is polygenic and is frequently associated with the spondyloarthro...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:10.3109/09273948.2016.1158283

    authors: Wakefield D,Yates W,Amjadi S,McCluskey P

    更新日期:2016-08-01 00:00:00

  • Uveal Effusion Associated with Presumed Viral Encephalitis.

    abstract::Background Uveal effusion is a rare disease that is characterized by exudative detachment of the ciliary body and choroid. Herein, we report a rare case of uveal effusion associated with viral encephalitis, which resolved following the treatment of the viral encephalitis and administration of corticosteroids. Case pre...

    journal_title:Ocular immunology and inflammation

    pub_type: 信件

    doi:10.1080/09273948.2020.1797110

    authors: Lee DH,Kim TY,Lee SC,Kim M

    更新日期:2020-08-20 00:00:00

  • Evaluation of the Anterior Segment Parameters of the Patients with Scleroderma.

    abstract:PURPOSE:To evaluate corneal parameters of scleroderma (SC) patients by Pentacam-HR. METHODS:Twenty-two eyes of 22 SC patients and 33 eyes of 33 control subjects were enrolled. All participants underwent Pentacam (Pentacam-HR, Oculus, Germany) evaluation. Both SC and control groups were divided into two subgroups as dr...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2015.1115079

    authors: Şahin M,Yüksel H,Şahin A,Cingü AK,Türkcü FM,Kaya S,Yazmalar L,Batmaz İ

    更新日期:2017-04-01 00:00:00

  • Clinical Characteristics of Inflammatory Choroidal Neovascularization in a Chinese Population.

    abstract:PURPOSE:To describe demographic features and clinical and imaging characteristics of inflammatory choroidal neovascularization (CNV) in a Chinese population. METHODS:A retrospective case review of patients with CNV secondary to uveitis from 2002 to 2013. RESULTS:A total of 125 patients (150 eyes, 166 CNVs; bifocal CN...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2015.1015741

    authors: Wu K,Zhang X,Su Y,Ji Y,Zuo C,Li M,Wen F

    更新日期:2016-06-01 00:00:00