Bacterial contamination of needles used for intravitreal injections: a prospective, multicenter study.

Abstract:

PURPOSE:To determine the incidence of bacterial contamination of needles used for intravitreal injections. METHODS:Patients undergoing intravitreal injections were enrolled prospectively. No pre-injection antibiotics were administered. Following povidone-iodine irrigation, conjunctival cultures were taken and the injection was performed. The needle was cultured. A dry control needle was exposed to the surgical field and cultured. RESULTS:No patients developed endophthalmitis. Eighteen injection needles (18%) yielded positive bacterial growth. The most commonly encountered organisms were Propionibacterium acnes (n = 8) and Staphylococcus epidermidis (n = 6). Four control needles showed positive growth, in 2 cases with the same organism as a matching positive used needle. The difference between contamination rates of used and control needles was significant (p = .002, McNemar's test). CONCLUSIONS:Bacterial contaminants are present on a substantial proportion of needles. Since the needle contacts both the ocular surface and the vitreous, it is possible that inoculation of the vitreous cavity occurs in such cases.

journal_name

Ocul Immunol Inflamm

authors

Stewart JM,Srivastava SK,Fung AE,Mahmoud TH,Telander DG,Hariprasad SM,Ober MD,Mruthyunjaya P

doi

10.3109/09273948.2010.520405

subject

Has Abstract

pub_date

2011-02-01 00:00:00

pages

32-8

issue

1

eissn

0927-3948

issn

1744-5078

journal_volume

19

pub_type

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