Diagnostic Markers in Ocular Sarcoidosis in A High TB Endemic Population - A Multicentre Study.

Abstract:

AIM:To look at markers to differentiate ocular sarcoidosis from ocular tuberculosis in a high TB endemic population. MATERIALS & METHODS:Retrospective multicenter study involving seven tertiary eyecare centers in India between July 2016 to December 2016. Demographic, clinical and laboratory data were retrieved from respective hospital databases. Group A included biopsy-proven ocular sarcoidosis while group B included ocular tuberculosis. RESULTS:Data from 2726 consecutive patients with uveitis were retrieved from the databases. Group A had 61 cases while group B included 307 cases. The mean age in group A was 43 ± 16.55 years while in group B was 38 ± 13.13 years. Females were more common in group A. Uveitis with low Schirmer test (OR-30, CI-95%), candlewax retinal vasculitis (OR-8.69, CI-95%), hilar lymphadenopathy (OR-15.23, CI-95%), fissural nodules (OR-39.11, CI-95%) had higher odds of having ocular sarcoidosis. CONCLUSION:Presence of dry eye, candlewax retinal vasculitis, hilar lymphadenopathy, and fissural nodules if present in a patient with uveitis, could help differentiate ocular sarcoidosis from ocular tuberculosis in a high TB endemic population.

journal_name

Ocul Immunol Inflamm

authors

Babu K,Biswas J,Agarwal M,Mahendradas P,Bansal R,Rathinam SR,Basu S,Ganesh SK,Konana VK,Vedhanayaki R,Philips M,Choudhary T

doi

10.1080/09273948.2020.1778733

subject

Has Abstract

pub_date

2020-09-01 00:00:00

pages

1-5

eissn

0927-3948

issn

1744-5078

pub_type

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