Abstract:
PURPOSE:To investigate demographic, clinical features and complications of Italian patients with ocular Behçet's disease (BD) over time. METHODS:Retrospective study of 385 patients examined from 1968 to 2011, 265 of whom had follow-up ≥ 12 months. RESULTS:A significant increase in the proportion of females (p = 0.03) and anterior uveitis (p < 0.001), and a decrease in the complete type of BD in all patients (p = 0.003) and in males (p = 0.002), and in hypopyon (p = 0.024) were observed over time. Optic neuropathy (p < 0.0001), maculopathy (p = 0.002), retinal detachment, and retinal neovascularization (p = 0.02) decreased over time, with no difference between genders, concomitant with an increase in the use of immunosuppressive drugs (p = 0.003). Visual acuity ≤1/10 was detected more often in males than females (p = 0.003). CONCLUSIONS:A significant shift in clinical manifestations of BD patients was observed over 44 years. Immunosuppressive therapy succeeded in lowering ocular complications. The incidence of ocular BD is increasing in females, but visual prognosis is still worse in males.
journal_name
Ocul Immunol Inflammjournal_title
Ocular immunology and inflammationauthors
Accorinti M,Pesci FR,Pirraglia MP,Abicca I,Pivetti-Pezzi Pdoi
10.3109/09273948.2015.1094095subject
Has Abstractpub_date
2017-02-01 00:00:00pages
29-36issue
1eissn
0927-3948issn
1744-5078journal_volume
25pub_type
杂志文章abstract:PURPOSE:To report a case of subretinal fibrosis and uveitis syndrome in association with ectodermal dysplasia. METHODS:Chart review of a patient with subretinal fibrosis and uveitis syndrome and ectodermal dysplasia. RESULTS:The authors identified one case of a patient with the diagnoses of subretinal fibrosis and uv...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273940903168670
更新日期:2009-09-01 00:00:00
abstract:PURPOSE:To compare Behçet uveitis patients who presented in the 1990s and 2000s. METHODS:Records of 170 patients seen in 1990-1994 and 258 patients seen in 2000-2004 were reviewed. Presenting features were analyzed in the whole cohort. Uveitis attacks, vision, complications, and immunomodulatory treatment (IMT) were c...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2012.713159
更新日期:2012-12-01 00:00:00
abstract::Purpose: To evaluate retinal and choroidal microvascular features of VKH patients in acute and convalescent phases after treatment using OCTA.Methods: A prospective, observational study was conducted in patients with initial VKH at the acute stage (n = 15) and healthy participants (n = 15) served as controls. After 3-...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1695856
更新日期:2020-01-03 00:00:00
abstract:PURPOSE:To compare QuantiFERON®-TB Gold and tuberculin skin testing as diagnostic tests for intraocular tuberculosis in HIV positive and negative patients. METHODS:A prospective study evaluating two different tests to help diagnose intraocular tuberculosis. RESULTS:Thirty-five of 106 patients (33.0%) were diagnosed w...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2017.1327078
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:To describe the medical treatment of severe ocular hypotony in HIV-seropositive patients with cytomegalovirus retinitis and cidofovir-associated uveitis. PATIENTS AND METHODS:Two HIV-seropositive patients with cytomegalovirus retinitis and cidofovir-associated uveitis complicated by severe ocular hypotony we...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1076/ocii.9.3.211.3968
更新日期:2001-09-01 00:00:00
abstract:PURPOSE:To study the safety and efficacy of intravitreal injection of dexamethasone implant in the management of posterior segment involvement in tubercular uveitis (TBU). METHODS:In this study, retrospective analysis of safety and efficacy of intravitreal injection of dexamethasone implant for various indications suc...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2017.1400074
更新日期:2018-01-01 00:00:00
abstract::Purpose: To compare the clinical characteristics of patients with active episodes of ocular toxoplasmosis from three provinces, Misiones, Santa Fe, and Buenos Aires, Argentina. Methods: Patients with a diagnosis of ocular toxoplasmosis from three databases of four tertiary referral uveitis centers were reviewed. Colle...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1484494
更新日期:2019-01-01 00:00:00
abstract::Herpes simplex virus, varicella zoster virus, human cytomegalovirus, and rubella virus are the most common causes of virus-induced anterior uveitis. They can present in a variety of entities not only with typical but also overlapping clinical characteristics. These viral infections are commonly associated with ocular ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:10.1080/09273948.2018.1439069
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:To report outcomes and assess structural changes in the retina in patients with severe endophthalmitis. METHODS:Retrospective, nonrandomized, interventional case series at a tertiary referral centre. Spectral domain optical coherence tomography (OCT) images of both eyes were acquired at least 5 months after pa...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2014.949780
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:To describe the clinical course of uveitis-associated inflammatory papillitis and evaluate the utility and reproducibility of optic nerve spectral domain optical coherence tomography (SD-OCT). METHODS:Data on 22 eyes of 14 patients with uveitis-related papillitis and optic nerve imaging were reviewed. SD-OCT m...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2014.991041
更新日期:2016-01-01 00:00:00
abstract::Purpose: To emphasize the different manifestations of ocular involvement in Whipple disease with challenge in establishing the diagnosis as clinical, laboratory, and histological features could mimic other uveitis entities. Methods: Case reports of three patients. Results: The first patient was an African male sufferi...
journal_title:Ocular immunology and inflammation
pub_type: 信件
doi:10.1080/09273948.2018.1518461
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To assess the value of fluorine-18 fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) in patients with unexplained chronic uveitis. METHODS:Retrospective review of 19 (18)F-FDG PET scans. All patients had normal chest CT. In the final analysis, the authors used criteria similar to the criteria of ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940902788221
更新日期:2009-05-01 00:00:00
abstract::Purpose: To describe with multimodal imaging a case of post-infectious unilateral outer retinopathy with choroiditis. Methods: Retrospective chart review of a case of a 67-year old male who presented following the onset of viral symptoms with an acute onset outer retinopathy, small vessel leakage on fluorescein angiog...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1485954
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:Longitudinal evaluation of acute exudative polymorphous paraneoplastic vitelliform maculopathy (AEPPVM) following diagnosis and treatment of metastatic melanoma. METHODS:Case report of a 47-year-old male with unknown primary metastatic melanoma and AEPPVM monitored before and during melanoma treatment using cl...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2020.1813782
更新日期:2020-10-06 00:00:00
abstract:PURPOSE:To describe a strategy for reducing the risk of posterior dislocation of a fluocinolone implant during exchange or removal. DESIGN:Case report and in vitro model. METHODS:Description of a surgical case and an in vitro experiment evaluating the role of infusion pressure in maintaining implant stability in surg...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2011.553980
更新日期:2011-06-01 00:00:00
abstract:PURPOSE:To report a rare case of intermediate uveitis following rubella infection in pregnancy. DESIGN:Case report. METHODS:A 35-year-old pregnant woman, at 24 weeks of gestation, presented with sudden floaters and blurring of vision of the left eye. Ocular examination revealed vitritis 1-2+ with no retinal involveme...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2011.555593
更新日期:2011-06-01 00:00:00
abstract::In eyes with suspected endophthalmitis, early diagnosis and appropriate treatment have been noted to be associated with a better visual outcome. Currently, however, confirmation of the diagnosis of endophthalmitis (bacterial and/or fungal) is dependent on conventional techniques of microbiological isolation of organis...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:
更新日期:2000-09-01 00:00:00
abstract:PURPOSE:To describe demographic features and clinical and imaging characteristics of inflammatory choroidal neovascularization (CNV) in a Chinese population. METHODS:A retrospective case review of patients with CNV secondary to uveitis from 2002 to 2013. RESULTS:A total of 125 patients (150 eyes, 166 CNVs; bifocal CN...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2015.1015741
更新日期:2016-06-01 00:00:00
abstract::Purpose: To describe the long-term clinical outcomes in a cohort of uveitic eyes treated with the intravitreal dexamethasone implant (Ozurdex; Allergan, Inc).Methods: Seventy-nine (63 patients) receiving 134 implant injections over 82 months were included. Indication, visual acuity (VA), intraocular pressure (IOP), vi...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1578380
更新日期:2020-01-01 00:00:00
abstract::Introduction: Uveitis is an important cause of blindness and ocular morbidity in the world. The patterns of uveitis have not been well characterized in sub-Saharan Africa. Purpose: To describe the characteristics of uveitis among patients presenting to Jimma University Department of Ophthalmology (JUDO) from July 2013...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1644348
更新日期:2020-10-02 00:00:00
abstract:PURPOSE:To report a patient with submacular hemorrhage due to retinal angiomatous proliferation (RAP) in tubercular retinal vasculitis (TRV). METHODS:Case report. RESULTS:We report a 33-year-old Asian Indian patient of TRV presenting with capillary non-perfusion areas, submacular hemorrhage and venous loops. The pati...
journal_title:Ocular immunology and inflammation
pub_type: 信件
doi:10.1080/09273948.2020.1803363
更新日期:2020-09-25 00:00:00
abstract::Experimental autoimmune uveoretinitis (EAU) induced by immunization of male Lewis rats with bovine S-antigen (S-Ag) is prevented by injection of S-Ag into the testis prior to immunization. This protection of animals is due to the induction of systemic immunotolerance or immunosuppression, which the authors designate o...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273949509085041
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:To report an immunocompetent patient with Nocardia exalbida endogenous endophthalmitis. DESIGN:Case report. METHODS:Clinical-pathologic correlation and microbiologic evaluation were performed on an enucleated eye. RESULTS:A 56-year-old man presented with rapidly progressive vision loss associated with a post...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:10.3109/09273948.2011.563898
更新日期:2011-08-01 00:00:00
abstract::Immune Reconstitution Inflammatory Syndrome (IRIS) is an inflammatory syndrome in the context of immune restoration directed at a specific infectious antigen despite resolution of infection, often associated with opportunistic infections. IRIS has been reported in 30% to 35% of HIV patients who have cryptococcosis in ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273940903003505
更新日期:2009-09-01 00:00:00
abstract:PURPOSE:To describe treatment practices for ocular toxoplasmosis among members of the Brazilian Uveitis Society. METHODS:An online questionnaire sent to specialists, between October 2014 and March 2015. RESULTS:Most respondents (67.9%) treat all active cases. Most specialists consider visual acuity <20/200 (88.2%), s...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2016.1215471
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:To describe the clinical presentations of inflammatory choroidal neovascular membranes (CNVMs) and factors leading to their delayed diagnosis. METHODS:Retrospective analysis of chart records and digital images of 60 patients (73 eyes) with inflammatory CNVM (January 1998 to December 2013) to obtain demographic...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2016.1160128
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:The study was to evaluate the diagnostic efficacy of nested polymerase chain reaction (nPCR) using primers targeting B1 gene of Toxoplasma gondii (T. gondii) with Witmer Desmonts coefficient (WDC) technique in intraocular fluids of clinically suspected toxoplasma retino choroiditis (TRC) patients. MATERIALS ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940500545692
更新日期:2006-04-01 00:00:00
abstract::Purpose: To compare toll-like receptors 2 (TLR2) and 4 (TLR4) expression in cells of corneal and conjunctival epithelium between unilateral KC patients and control subjects. Methods: Prospective cross-sectional case-control study, including 50 unilateral KC patients and 20 control subjects. TLR2 and TLR4 expression wa...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1511813
更新日期:2019-01-01 00:00:00
abstract::Purpose: To evaluate the efficacy and safety of intravitreal ganciclovir (GCV) injection in refractory endotheliitis.Methods: Retrospectively recruited 25 eyes with endotheliitis, proved by clinical manifestations, positive PCR for viral DNA and responded poor to topical and systemic antiviral medications. All patient...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1573261
更新日期:2020-01-01 00:00:00
abstract::Intraocular manifestations of tuberculosis (TB) are rare, but TB infection is common worldwide, especially in developing economies, and in immigrant populations and immunocompromised patients in developed nations. The current review focuses on the clinical characteristics and diagnostic modalities useful in the diagno...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:10.3109/09273948.2010.489729
更新日期:2010-08-01 00:00:00