Abstract:
:Intraocular manifestations of tuberculosis (TB) are rare, but TB infection is common worldwide, especially in developing economies, and in immigrant populations and immunocompromised patients in developed nations. The current review focuses on the clinical characteristics and diagnostic modalities useful in the diagnosis of intraocular TB. Specifically, IFN-gamma Release Assays (IGRAs), antigen-detection assays, and polymerase chain reactions will be discussed. Clinical management of TB patients includes counseling and testing for HIV infection. The use of corticosteroids along with anti-tuberculous medications and special therapeutic considerations in immunocompromised patients are discussed.
journal_name
Ocul Immunol Inflammjournal_title
Ocular immunology and inflammationauthors
Cutrufello NJ,Karakousis PC,Fishler J,Albini TAdoi
10.3109/09273948.2010.489729subject
Has Abstractpub_date
2010-08-01 00:00:00pages
281-91issue
4eissn
0927-3948issn
1744-5078journal_volume
18pub_type
杂志文章,评审abstract::Purpose: To review early withdrawal of immunomodulatory therapy (IMT) for birdshot retinochoroidopathy (BSRC). Design: Retrospective case-series of sixteen patients with Human-leukocyte-antigen-A29-positive BSRC treated with IMT ≥ 1 year and discontinued prior to achieving durable remission, observed ≥ 6 months off IM...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1506040
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To evaluate the clinical outcome and safety of adalimumab in patients with Vogt-Koyanagi-Harada (VKH) disease. METHODS:VKH patients treated with adalimumab seen at the University of Buenos Aires were reviewed. Main outcome measures were visual acuity, anterior segment inflammation, optic nerve inflammation (ON...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2016.1236969
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:To compare clinical characteristics and visual prognosis between HLA-B27-associated uveitis patients with and without posterior segment involvement. METHODS:Medical records of 78 patients with HLA-B27-associated uveitis were retrospectively analyzed. RESULTS:Neither demographic nor clinical characteristics we...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940802553261
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:To analyze the clinical features, course, management, and outcomes of tubercular (TB) uveitis in the pediatric population and assess the response to anti-tubercular therapy (ATT). METHODS:Hospital records of children (≤16 years) from a large tertiary-care institute between January 2001 and December 2015 were r...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2017.1296579
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:To determine the prevalence of viral infections in patients with hypertensive anterior uveitis in Thailand from polymerase chain reaction (PCR) of aqueous humor. METHODS:Thirty-one patients with anterior uveitis with intraocular pressure (IOP) above 25 mmHg were included for PCR analysis for cytomegalovirus (C...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1678651
更新日期:2020-05-18 00:00:00
abstract::Purpose: To describe the long-term clinical outcomes in a cohort of uveitic eyes treated with the intravitreal dexamethasone implant (Ozurdex; Allergan, Inc).Methods: Seventy-nine (63 patients) receiving 134 implant injections over 82 months were included. Indication, visual acuity (VA), intraocular pressure (IOP), vi...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1578380
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:Copper (Cu) is an essential trace element; however excess is toxic due to the pro-oxidant activity. Increased intracellular Cu levels in vitreous and monocyte were reported in Eales disease (ED) previously. Copper transporter1 (CTR1) maintains copper homeostasis and hence, we studied the presence of CTR1 in ocu...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2015.1071404
更新日期:2016-12-01 00:00:00
abstract::Purpose: To evaluate retinal and choroidal microvascular features of VKH patients in acute and convalescent phases after treatment using OCTA.Methods: A prospective, observational study was conducted in patients with initial VKH at the acute stage (n = 15) and healthy participants (n = 15) served as controls. After 3-...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1695856
更新日期:2020-01-03 00:00:00
abstract:PURPOSE:To report the results of tocilizumab (TCZ) treatment in patients with Behçet uveitis (BU) who had failed conventional, interferon alpha, and anti-Tumor necrosis factor-alpha therapy. METHODS:We reviewed the records of five patients with BU treated with monthly infusions of TCZ 8 mg/kg. Outcome measures were vi...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2017.1355471
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:To investigate prognostic factors for retinal sensitivity assessed by microperimetry in patients with Vogt-Koyanagi-Harada (VKH) disease. METHODS:In total, 34 patients with initial-onset acute disease and 19 patients with chronic recurrent disease were retrospectively evaluated. RESULTS:The mean follow-up per...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2016.1139730
更新日期:2017-08-01 00:00:00
abstract:PURPOSE:To describe ocular manifestations and particularly optical coherence tomography (OCT) findings in choroidopathy revealing a systemic lupus erythematosus, without systemic hypertension. METHODS:Observational case report. RESULTS:The diagnosis of systemic lupus erythematosus choroidopathy was suggested by the o...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273940903353785
更新日期:2010-04-01 00:00:00
abstract:PURPOSE:To describe the clinical course of uveitis-associated inflammatory papillitis and evaluate the utility and reproducibility of optic nerve spectral domain optical coherence tomography (SD-OCT). METHODS:Data on 22 eyes of 14 patients with uveitis-related papillitis and optic nerve imaging were reviewed. SD-OCT m...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2014.991041
更新日期:2016-01-01 00:00:00
abstract::Introduction: Uveitis is an important cause of blindness and ocular morbidity in the world. The patterns of uveitis have not been well characterized in sub-Saharan Africa. Purpose: To describe the characteristics of uveitis among patients presenting to Jimma University Department of Ophthalmology (JUDO) from July 2013...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1644348
更新日期:2020-10-02 00:00:00
abstract:BACKGROUND:To evaluate the safety and efficacy of intravitreal triamcinolone acetonide (TA) for treating macular edema secondary to non-infectious uveitis. METHODS:Retrospective review of sixteen patients (20 eyes) with chronic cystoid macular edema (CME) as a consequence of controlled intermediate uveitis, posterior ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940590933511
更新日期:2005-04-01 00:00:00
abstract:PURPOSE:To compare QuantiFERON®-TB Gold and tuberculin skin testing as diagnostic tests for intraocular tuberculosis in HIV positive and negative patients. METHODS:A prospective study evaluating two different tests to help diagnose intraocular tuberculosis. RESULTS:Thirty-five of 106 patients (33.0%) were diagnosed w...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2017.1327078
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:To report a challenging case of unilateral choroidal effusion. METHODS:A case report about patient who presented with unilateral choroidal effusion and who was taking sulfonamides. Patient has been under care of a multidisciplinary team of uveitis consultant, ocular oncology consultant, and systemic oncology c...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2020.1770300
更新日期:2020-07-09 00:00:00
abstract:AIM:To compare outcomes of live related limbal allograft (Lr-CLAL) versus cadaveric keratolimbal allograft (KLAL) in limbal stem cell deficiency (LSCD) secondary to ocular burns. METHODS:Twenty patients with stage IIb LSCD were randomized so that cases underwent either Lr-CLAL or KLAL. Fibrovascular pannus was removed...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,随机对照试验
doi:10.3109/09273948.2014.902076
更新日期:2015-06-01 00:00:00
abstract:PURPOSE:To describe a case of sympathetic ophthalmia following vitrectomy for endophthalmitis after an intravitreal injection of bevacizumab. DESIGN:Retrospective case report. METHODS:An 84-year-old male developed sympathetic ophthalmia 4 months after vitrectomy for endophthalmitis following an intravitreal injection...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940802409951
更新日期:2008-09-01 00:00:00
abstract:PURPOSE:To investigate the changes of effector-related phenotypic markers and the natural killer (NK)-like effector functions of CD8(bright)CD56+ T cells in patients with Behçet uveitis after combined cyclosporine and prednisone (Cs/Pd) treatment. METHODS:Ten patients with active Behçet panuveitis and 10 healthy contr...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940600966616
更新日期:2006-10-01 00:00:00
abstract::In a South Indian study, an 'in-house' enzyme-linked immunosorbent assay (ELISA) was developed to evaluate the potential of herpes simplex virus (HSV)-specific tear secretory IgA (sIgA) in the diagnosis of herpes simplex keratitis (HSK). The presence of HSV-specific tear sIgA was found to be diagnostic in 20.28% of ca...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1076/ocii.7.2.61.4023
更新日期:1999-06-01 00:00:00
abstract:PURPOSE:To establish how much uveitis patients know about their own condition and to investigate the contribution of demographic factors to that knowledge. METHODS:A self-designed questionnaire, comprising 20 questions about uveitis, was distributed to 200 consecutive patients attending a uveitis clinic. The questionn...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2016.1175638
更新日期:2017-12-01 00:00:00
abstract:PURPOSE:To describe scleral changes in chronic VKH. METHODS:Medical records of patients with chronic VKH were retrospectively reviewed. Change of scleral architecture was defined as progressive posterior bowing on OCT, axial length elongation, and/or increased myopia more than -1.0 D, not explicable by other etiologie...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2015.1057600
更新日期:2017-02-01 00:00:00
abstract::Purpose: To review the broad spectrum of clinical neuro-ophthalmic presentations associated with human immunodeficiency virus (HIV) infection. Methods: Critical review of the literature regarding neuro-ophthalmic consequences of HIV infection and its sequelae. Results: Neuro-ophthalmological diseases are common in bot...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1704024
更新日期:2020-10-02 00:00:00
abstract::Onchocercal keratitis (river blindness) is one of the leading worldwide causes of blindness. Light microscopic analysis of human specimens and corneal tissue from experimental models has implicated the eosinophil as an important cell in the inflammatory response. Our previous studies in experimental murine onchocercal...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273949709116890
更新日期:1997-09-01 00:00:00
abstract::Purpose: The purpose of the article is to describe a novel case of idiopathic central nervous system inflammatory disease with bilateral human leukocyte antigen (HLA)-B27-positive anterior uveitis. Methods/Results: A 15-year-old African American boy with bilateral HLA-B27-positive anterior uveitis controlled with topi...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1449865
更新日期:2019-01-01 00:00:00
abstract::Recent reports have shown that dry eye in Sjögren's syndrome (SS) is associated with reactivation of Epstein-Barr virus (EBV) in lacrimal glands. However, the number of patients examined were few and it has not been determined whether dry eye in the absence of SS is also related to EBV reactivation. The authors exam...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273949409057066
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND/AIMS:To compare different existent implants for noninfectious uveitis. METHODS:We performed a systematic review of randomized clinical trials (RCTs), searching in five electronic databases and screening reference lists of included studies and relevant reviews. We performed network meta-analysis to compare 0...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2020.1787463
更新日期:2020-08-18 00:00:00
abstract::Acute anterior uveitis (AAU) is the commonest type of uveitis and HLA-B27 AAU is the most frequently recognized type of acute anterior uveitis and anterior uveitis overall. Recent evidence indicates that acute anterior uveitis is a heterogenous disease, is polygenic and is frequently associated with the spondyloarthro...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:10.3109/09273948.2016.1158283
更新日期:2016-08-01 00:00:00
abstract::Purpose: To assess changes in aqueous humor (AH) levels of cytokines following dexamethasone intravitreal implant (DEX) injection for diabetic macular edema (DME).Methods: Sixteen DME and cataract cases series study. Anterior chamber AH sampling was performed at baseline at DEX injection time (T1), cataract surgery 8 ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1636095
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To present a population of patients sharing atypical manifestations of vitreoretinal lymphoma (VRL). METHODS:Institutional case series in a single tertiary center. Patients with cytologically proven VRL, referred between November 2009 and May 2010, were retrospectively reviewed. Diagnosis of VRL was based on c...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2013.835427
更新日期:2014-06-01 00:00:00