Live Related versus Cadaveric Limbal Allograft in Limbal Stem Cell Deficiency.

Abstract:

AIM:To compare outcomes of live related limbal allograft (Lr-CLAL) versus cadaveric keratolimbal allograft (KLAL) in limbal stem cell deficiency (LSCD) secondary to ocular burns. METHODS:Twenty patients with stage IIb LSCD were randomized so that cases underwent either Lr-CLAL or KLAL. Fibrovascular pannus was removed and superficial keratectomy done on the recipient bed. Limbal lenticule of 2-3 clock hours' length was harvested from the donor, which was placed over the host bed and sutured followed by bandage contact lens application. Parameters assessed were uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), conjunctivalization, corneal neovascularization, epithelial defects, corneal clarity, Schirmer's test, tear film breakup time (tBUT), and ultrasonic pachymetry. RESULTS:At 6 months follow-up, the Lr-CLAL group had a higher gain in vision (p = 0.029), decrease in conjunctivalization (p = 0.009), and increase in Schirmer's values (p = 0.009). CONCLUSION:Lr-CLAL seems to have better result in terms of vision gain and ocular surface restoration.

journal_name

Ocul Immunol Inflamm

authors

Titiyal JS,Sharma N,Agarwal AK,Prakash G,Tandon R,Vajpayee R

doi

10.3109/09273948.2014.902076

subject

Has Abstract

pub_date

2015-06-01 00:00:00

pages

232-9

issue

3

eissn

0927-3948

issn

1744-5078

journal_volume

23

pub_type

杂志文章,随机对照试验
  • Evaluation of the Accuracy of T-SPOT.TB for the Diagnosis of Ocular Tuberculosis in a BCG-vaccinated, Non-endemic Population.

    abstract:PURPOSE:To determine the performance of T-SPOT.TB, an interferon gamma release assay test, in patients with ocular tuberculosis (TB) in a BCG-vaccinated, non-endemic population. METHODS:We employed a nested case-control design. In total, 45 subjects were enrolled (23 patients with ocular tuberculosis and 22 patients w...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2015.1135965

    authors: Urzua CA,Liberman P,Abuauad S,Sabat P,Castiglione E,Beltran-Videla MA,Aguilera R

    更新日期:2017-08-01 00:00:00

  • Antigen-presenting cells are targets of regulatory T cells similar to those that mediate anterior chamber-associated immune deviation.

    abstract:PURPOSE:To identify the means by which in-vitro-generated regulatory T cells, similar to those in anterior chamber-associated immune deviation (ACAID), suppress antigen-specific T-cell responses. METHODS:T regulators (T regs), generated by stimulating ovalbumin (OVA)-specific Tcr transgenic DO11.10 T cells with OVA-pu...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940490895317

    authors: Yokoi H,Streilein JW

    更新日期:2004-06-01 00:00:00

  • Intravitreal Ranibizumab for the Treatment of Irvine-Gass Syndrome.

    abstract:PURPOSE:The purpose of our study was to evaluate the potential efficacy and safety of intravitreal ranibizumab in patients with pseudophakic cystoid macular edema (CME). METHODS:This retrospective study comprised 7 eyes with CME treated with intravitreal ranibizumab. Patients were examined at 1 week and 1 month after ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2014.898775

    authors: Mitropoulos PG,Chatziralli IP,Peponis VG,Drakos E,Parikakis EA

    更新日期:2015-06-01 00:00:00

  • The Role of Dexamethasone Implant in the Management of Tubercular Uveitis.

    abstract:PURPOSE:To study the safety and efficacy of intravitreal injection of dexamethasone implant in the management of posterior segment involvement in tubercular uveitis (TBU). METHODS:In this study, retrospective analysis of safety and efficacy of intravitreal injection of dexamethasone implant for various indications suc...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2017.1400074

    authors: Agarwal A,Handa S,Aggarwal K,Sharma M,Singh R,Sharma A,Agrawal R,Sharma K,Gupta V

    更新日期:2018-01-01 00:00:00

  • Changes in Scleral Architecture in Chronic Vogt-Koyanagi-Harada Disease.

    abstract:PURPOSE:To describe scleral changes in chronic VKH. METHODS:Medical records of patients with chronic VKH were retrospectively reviewed. Change of scleral architecture was defined as progressive posterior bowing on OCT, axial length elongation, and/or increased myopia more than -1.0 D, not explicable by other etiologie...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2015.1057600

    authors: Harada Y,Bhat P,Munk MR,Goldstein DA

    更新日期:2017-02-01 00:00:00

  • Clinical Characteristics of Inflammatory Choroidal Neovascularization in a Chinese Population.

    abstract:PURPOSE:To describe demographic features and clinical and imaging characteristics of inflammatory choroidal neovascularization (CNV) in a Chinese population. METHODS:A retrospective case review of patients with CNV secondary to uveitis from 2002 to 2013. RESULTS:A total of 125 patients (150 eyes, 166 CNVs; bifocal CN...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2015.1015741

    authors: Wu K,Zhang X,Su Y,Ji Y,Zuo C,Li M,Wen F

    更新日期:2016-06-01 00:00:00

  • Effect of Allergic Diseases on Keratoconus Severity.

    abstract:PURPOSE:To investigate the association between keratoconus (KC) and allergic diseases. METHODS:In a prospective age- and sex-matched case--control study clinical data of 885 KC patients and 1526 controls were evaluated regarding the presence of various allergic diseases. Severity of KC and ophthalmic parameters of KC ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2016.1145697

    authors: Naderan M,Rajabi MT,Zarrinbakhsh P,Bakhshi A

    更新日期:2017-06-01 00:00:00

  • devR PCR for the diagnosis of intraocular tuberculosis.

    abstract:PURPOSE:To compare the efficacy of devR and MPB64 PCR in the diagnosis of intraocular tuberculosis. METHODS:Prospective, nonrandomized study. Seventy-five patients were enrolled in 3 groups. Group A had 25 patients with presumed intraocular tubercular uveitis, group B had 25 controls with specific uveitis other than t...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2014.981550

    authors: Kataria P,Kumar A,Bansal R,Sharma A,Gupta V,Gupta A,Singh R,Sharma K

    更新日期:2015-02-01 00:00:00

  • Autoimmune retinopathy in a patient with autoimmune polyendocrine syndrome type I.

    abstract:PURPOSE:To present a case of autoimmune retinopathy resulting from a mutation in the autoimmune regulator (AIRE) gene. DESIGN:Case study. METHODS:Case review. RESULTS:Mild improvement of goldmann visual field following treatment with systemic and local immunosuppression. CONCLUSIONS:There are a limited number of ca...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2012.754906

    authors: Breunig A,Lee MS,Miller BS,Binstadt BA,Anderson MS,Montezuma S

    更新日期:2013-04-01 00:00:00

  • Predictive value of selected biomarkers, polymorphisms, and clinical features for oligoarticular juvenile idiopathic arthritis-associated uveitis.

    abstract:PURPOSE:Uveitis is the most common extra-articular manifestation of juvenile idiopathic arthritis (JIA) and is associated with considerable morbidity. The aim of this study was to examine the risk factors associated with uveitis in oligoarticular JIA. METHODS:We conducted a chart review of 86 patients with oligoarticu...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2013.841495

    authors: Pelegrín L,Casaroli-Marano R,Antón J,García de Vicuña MC,Molina-Prat N,Ignacio Aróstegui J,Yagüe J,Ríos J,Adán A

    更新日期:2014-06-01 00:00:00

  • A new OCT finding in tuberculous serpiginous-like choroidopathy.

    abstract:PURPOSE:To present a case of tubercular serpiginous-like choroiditis (SLC) with previously unreported choroidal findings on enhanced depth imaging OCT (EDI-OCT). DESIGN:Case report. METHODS:A 60-year-old female presented with decreased vision. Serpiginous choroidopathy was diagnosed. Laboratory workup revealed an inf...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2014.964421

    authors: Rifkin LM,Munk MR,Baddar D,Goldstein DA

    更新日期:2015-02-01 00:00:00

  • Ten-Year Retention Rate of Infliximab in Patients with Behçet's Disease-Related Uveitis.

    abstract:PURPOSE:To evaluate the 10-year drug retention rate of infliximab (IFX) in Behçet's disease (BD)-related uveitis, the effect of a concomitant use of disease modifying anti-rheumatic drugs (DMARDs) on drug survival and differences according to the lines of biologic treatment. METHODS:Cumulative survival rates were stud...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2017.1391297

    authors: Fabiani C,Sota J,Vitale A,Emmi G,Vannozzi L,Bacherini D,Lopalco G,Guerriero S,Venerito V,Orlando I,Franceschini R,Fusco F,Frediani B,Galeazzi M,Iannone F,Tosi GM,Cantarini L

    更新日期:2019-01-01 00:00:00

  • Causes of Hypertensive Anterior Uveitis in Thailand.

    abstract:PURPOSE:To determine the prevalence of viral infections in patients with hypertensive anterior uveitis in Thailand from polymerase chain reaction (PCR) of aqueous humor. METHODS:Thirty-one patients with anterior uveitis with intraocular pressure (IOP) above 25 mmHg were included for PCR analysis for cytomegalovirus (C...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1678651

    authors: Khieu C,Kongyai N,Pathanapitoon K,Van Der Eijk AA,Rothova A

    更新日期:2020-05-18 00:00:00

  • Epidemic Retinitis with Macular Edema -Treatment Outcome with and without Steroids.

    abstract::Purpose: To study treatment outcomes with and without oral corticosteroids in epidemic retinitis (ER).Method: A retrospective, observational study of 35 eyes of 29 patients diagnosed as ER. Days taken for resolution of macular edema and retinitis lesions were compared in patients treated with oral antibiotics (Group 1...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1704792

    authors: Kawali A,Srinivasan S,Mohan A,Bavaharan B,Mahendradas P,Shetty B

    更新日期:2020-01-21 00:00:00

  • Posterior segment involvement in Korean patients with HLA-B27-associated uveitis.

    abstract:PURPOSE:To compare clinical characteristics and visual prognosis between HLA-B27-associated uveitis patients with and without posterior segment involvement. METHODS:Medical records of 78 patients with HLA-B27-associated uveitis were retrospectively analyzed. RESULTS:Neither demographic nor clinical characteristics we...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940802553261

    authors: Kim SJ,Chung H,Yu HG

    更新日期:2009-01-01 00:00:00

  • A double-masked, randomized study to investigate the safety and efficacy of daclizumab to treat the ocular complications related to Behçet's disease.

    abstract:PURPOSE:To investigate the safety and efficacy of daclizumab (Zenapax, humanized anti-Tac, HAT) in controlling the ocular manifestations of Behçet's disease. DESIGN:Randomized, placebo-controlled, double-masked clinical trial. PARTICIPANTS:Seventeen participants with Behçet's disease experiencing at least two prior o...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/09273940701299370

    authors: Buggage RR,Levy-Clarke G,Sen HN,Ursea R,Srivastava SK,Suhler EB,Altemare C,Velez G,Ragheb J,Chan CC,Nussenblatt RB,Bamji AT,Sran P,Waldmann T,Thompson DJ

    更新日期:2007-03-01 00:00:00

  • Outcomes of treatment with immunomodulatory therapy in patients with corticosteroid-resistant juvenile idiopathic arthritis-associated chronic iridocyclitis.

    abstract:PURPOSE:To describe the clinical outcome of patients with juvenile idiopathic arthritis (IA)-associated chronic iridocyclitis unresponsive to conventional therapy, in whom inflammation was eventually controlled using immunomodulatory therapy (IMT), and to determine if patients treated early with IMT have better visual ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940590951061

    authors: Yu EN,Meniconi ME,Tufail F,Baltatzis S,Foster CS

    更新日期:2005-09-01 00:00:00

  • Anterior Segment Ischemia in Viper Bite.

    abstract:PURPOSE:To describe the clinical and histopathological features of post viper bite anterior segment ischemia. METHODS:Seven patients with ocular complications following viper bite referred to uveitis clinic had slit-lamp examination, intraocular pressure (IOP) measurement, and fundus evaluation. Iris and fundus fluore...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2014.907435

    authors: Sivakumar RR,Rao NA

    更新日期:2016-01-01 00:00:00

  • Bacterial contamination of needles used for intravitreal injections: a prospective, multicenter study.

    abstract:PURPOSE:To determine the incidence of bacterial contamination of needles used for intravitreal injections. METHODS:Patients undergoing intravitreal injections were enrolled prospectively. No pre-injection antibiotics were administered. Following povidone-iodine irrigation, conjunctival cultures were taken and the inje...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,多中心研究

    doi:10.3109/09273948.2010.520405

    authors: Stewart JM,Srivastava SK,Fung AE,Mahmoud TH,Telander DG,Hariprasad SM,Ober MD,Mruthyunjaya P

    更新日期:2011-02-01 00:00:00

  • Optical Coherence Tomography Imaging of Presumed Sarcoid Retinal and Optic Nerve Nodules.

    abstract:PURPOSE:To characterize nodular lesions of the retina and optic nerve with spectral-domain optical coherence tomography (SD-OCT) in patients with sarcoidosis. METHODS:This is a retrospective series of 6 eyes from 5 patients with an established diagnosis of sarcoidosis, with clinically detected nodules of the optic ner...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2014.971972

    authors: Goldberg NR,Jabs DA,Busingye J

    更新日期:2016-06-01 00:00:00

  • Rubella-related intermediate uveitis in pregnancy--a rare presentation.

    abstract:PURPOSE:To report a rare case of intermediate uveitis following rubella infection in pregnancy. DESIGN:Case report. METHODS:A 35-year-old pregnant woman, at 24 weeks of gestation, presented with sudden floaters and blurring of vision of the left eye. Ocular examination revealed vitritis 1-2+ with no retinal involveme...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2011.555593

    authors: Thirupathy A,Tajunisah I

    更新日期:2011-06-01 00:00:00

  • Neuro-Ophthalmic Manifestations of HIV Infection.

    abstract::Purpose: To review the broad spectrum of clinical neuro-ophthalmic presentations associated with human immunodeficiency virus (HIV) infection. Methods: Critical review of the literature regarding neuro-ophthalmic consequences of HIV infection and its sequelae. Results: Neuro-ophthalmological diseases are common in bot...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1704024

    authors: Gordon LK,Danesh-Meyer H

    更新日期:2020-10-02 00:00:00

  • Visual loss associated with rickettsial disease.

    abstract:UNLABELLED:Abstract Purpose: To characterize and analyze ocular involvement associated with visual loss in a cohort of patients with rickettsial disease. METHODS:Retrospective study of 16 eyes of 14 patients. RESULTS:Mean initial visual acuity (VA) was 20/63 (range, 20/800-20/25). White retinal lesions infiltrating i...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2013.848907

    authors: Kahloun R,Gargouri S,Abroug N,Sellami D,Ben Yahia S,Feki J,Khairallah M

    更新日期:2014-10-01 00:00:00

  • Boston Type I Keratoprosthesis Implantation Following Autologous Submandibular Gland Transplantation for End Stage Ocular Surface Disorders.

    abstract:PURPOSE:To describe the results of Boston keratoprosthesis implantation in a patient with Stevens-Johnson syndrome following autologous submandibular gland transplantation. DESIGN:Observational case report. METHODS:We report the case of a man diagnosed with Stevens-Johnson syndrome. Autologous submandibular gland tra...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2016.1234624

    authors: Gu J,Zhai J,Liao G,Chen J

    更新日期:2018-01-01 00:00:00

  • Optic nerve head morphology and visual field function in patients with AIDS and without infectious retinitis.

    abstract:PURPOSE:To evaluate morphology of the optic nerve head and visual field in AIDS patients without retinitis. METHODS:One randomly selected eye from 246 patients with AIDS without retinitis was evaluated from prospective multicenter Longitudinal Studies of Ocular Complications of AIDS. Stereo fundus photographs of OHN a...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.3109/09273948.2012.694552

    authors: Kozak I,Ahuja A,Gangaputra S,Van Natta ML,Thorne JE,Freeman WR

    更新日期:2012-10-01 00:00:00

  • Outcomes of cataract surgery in ocular cicatricial pemphigoid.

    abstract:PURPOSE:To report the outcomes of cataract surgery in ocular cicatricial pemphigoid (OCP). SETTING:L. V. Prasad Eye Institute, Hyderabad, India. DESIGN:Retrospective, interventional case series. METHODS:Patients diagnosed with OCP who had undergone cataract surgery were included. Staging of disease, type of surgery,...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2013.819106

    authors: Puranik CJ,Murthy SI,Taneja M,Sangwan VS

    更新日期:2013-12-01 00:00:00

  • OCT follow-up of systemic lupus erythematosus choroidopathy.

    abstract:PURPOSE:To describe ocular manifestations and particularly optical coherence tomography (OCT) findings in choroidopathy revealing a systemic lupus erythematosus, without systemic hypertension. METHODS:Observational case report. RESULTS:The diagnosis of systemic lupus erythematosus choroidopathy was suggested by the o...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273940903353785

    authors: Kouprianoff S,Chiquet C,Bouillet L,Romanet JP

    更新日期:2010-04-01 00:00:00

  • Virus-Induced Anterior Uveitis (VIAU) in Immunocompromised Patients.

    abstract:PURPOSE:To describe the clinical characteristics, diagnosis, and treatment of VIAU in immunocompromised patients. METHODS:A critical review of literature was performed. RESULTS:Diagnosis and treatment of VIAU in immunocompromised patients may be a challenge due to atypical clinical-courses, severe presentations, and ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:10.1080/09273948.2018.1483519

    authors: de-la-Torre A

    更新日期:2018-01-01 00:00:00

  • Isolated Nocardia exalbida endogenous endophthalmitis.

    abstract:PURPOSE:To report an immunocompetent patient with Nocardia exalbida endogenous endophthalmitis. DESIGN:Case report. METHODS:Clinical-pathologic correlation and microbiologic evaluation were performed on an enucleated eye. RESULTS:A 56-year-old man presented with rapidly progressive vision loss associated with a post...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:10.3109/09273948.2011.563898

    authors: Milman T,Trubnik V,Shah M,McCormick SA,Finger PT

    更新日期:2011-08-01 00:00:00

  • Diagnostic Markers in Ocular Sarcoidosis in A High TB Endemic Population - A Multicentre Study.

    abstract:AIM:To look at markers to differentiate ocular sarcoidosis from ocular tuberculosis in a high TB endemic population. MATERIALS & METHODS:Retrospective multicenter study involving seven tertiary eyecare centers in India between July 2016 to December 2016. Demographic, clinical and laboratory data were retrieved from re...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2020.1778733

    authors: Babu K,Biswas J,Agarwal M,Mahendradas P,Bansal R,Rathinam SR,Basu S,Ganesh SK,Konana VK,Vedhanayaki R,Philips M,Choudhary T

    更新日期:2020-09-01 00:00:00