The Role of Dexamethasone Implant in the Management of Tubercular Uveitis.

Abstract:

PURPOSE:To study the safety and efficacy of intravitreal injection of dexamethasone implant in the management of posterior segment involvement in tubercular uveitis (TBU). METHODS:In this study, retrospective analysis of safety and efficacy of intravitreal injection of dexamethasone implant for various indications such as cystoid macular edema (CME), vitritis, or paradoxical worsening in TB-related intermediate uveitis, retinal vasculitis, and multifocal serpiginoid choroiditis (MSC) was performed. RESULTS:The study included 17 patients (19 eyes; 7 males). IOP increased from 14.88 ± 2.68 mm Hg to 16.4 ± 5.82 mm Hg (p = 0.18) at 3 months. BCVA improved from 0.37 ± 0.35 to 0.27 ± 0.21 at 3 months (p = 0.03). CME resolved at 3 months and two patients with paradoxical worsening showed resolution within 1 month. CONCLUSION:Intravitreal dexamethasone implant is safe and efficacious as an adjunct to ATT in reducing the central macular thickness, vitritis, and progression of choroiditis lesions in paradoxical worsening of MSC.

journal_name

Ocul Immunol Inflamm

authors

Agarwal A,Handa S,Aggarwal K,Sharma M,Singh R,Sharma A,Agrawal R,Sharma K,Gupta V

doi

10.1080/09273948.2017.1400074

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

884-892

issue

6

eissn

0927-3948

issn

1744-5078

journal_volume

26

pub_type

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