Optical Coherence Tomography Imaging of Presumed Sarcoid Retinal and Optic Nerve Nodules.

Abstract:

PURPOSE:To characterize nodular lesions of the retina and optic nerve with spectral-domain optical coherence tomography (SD-OCT) in patients with sarcoidosis. METHODS:This is a retrospective series of 6 eyes from 5 patients with an established diagnosis of sarcoidosis, with clinically detected nodules of the optic nerve or retina. All lesions were imaged with fundus photography and SD-OCT on presentation, and followed with serial imaging after treatment with corticosteroids and/or immunomodulatory therapy. RESULTS:Spectral OCT through the lesions revealed nodular hyperreflective processes obscuring the retinal layers or optic cup, with local structural changes, including subretinal and intraretinal fluid. After treatment with corticosteroids and/or immunosuppression in 4 followed patients, all lesions regressed with improvement in associated structural changes, but did not entirely disappear. CONCLUSIONS:Spectral OCT can be useful in identifying lesion morphology and location, and in tracking the response to treatment in eyes with posterior-segment nodules, presumably secondary to sarcoidosis.

journal_name

Ocul Immunol Inflamm

authors

Goldberg NR,Jabs DA,Busingye J

doi

10.3109/09273948.2014.971972

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

293-6

issue

3

eissn

0927-3948

issn

1744-5078

journal_volume

24

pub_type

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