Incidence and Risk Factors for Developing Glaucoma Among Patients with Uveitis in a University-based Tertiary Referral Center in Riyadh, Saudi Arabia.

Abstract:

PURPOSE:To investigate the incidence and risk factors of secondary glaucoma among uveitis patients. METHODS:Retrospective review of medical records of 642 patients (1220 eyes). RESULTS:Glaucoma was diagnosed in 169 (13.9%) eyes and was most common in eyes with anterior uveitis (19.1%) (p < 0.001). HLA-B27-positive anterior uveitis (27.6%), Fuchs' uveitis (23.3%), juvenile idiopathic arthritis (23.1%), herpetic uveitis (20.3%), and Vogt-Koyanagi-Harada disease (16.3%) were the leading clinical entities associated with glaucoma (p < 0.001). Significant risk factors at presentation included worse visual acuity, elevated intraocular pressure, keratic precipitates, granulomatous inflammation, anterior chamber reaction≥ 2+, posterior synechiae, and cataract. Female gender and iris nodules significantly predicted the need for glaucoma surgery. Visual outcome was worse in eyes with glaucoma than in eyes without glaucoma. CONCLUSIONS:Incidence of glaucoma differed depending on anatomic and etiologic diagnoses of uveitis. There is a significant association between severity of inflammation at presentation and development of glaucoma.

journal_name

Ocul Immunol Inflamm

authors

Al Rubaie K,Al Dhahri H,Al Fawaz A,Hemachandran S,Mousa A,Mohamed AG,Al-Obeidan SA,Abu El-Asrar AM

doi

10.3109/09273948.2015.1047036

subject

Has Abstract

pub_date

2016-10-01 00:00:00

pages

571-8

issue

5

eissn

0927-3948

issn

1744-5078

journal_volume

24

pub_type

杂志文章
  • Case Report: Bilateral Granulomatous Anterior Uveitis in HIV-patient with Disseminated Talaromycosis (penicilliosis) Marneffei Infection.

    abstract::We report on a 22-years-old Thai male patient with congenital HIV infection. Due to his non-adherence to antiretroviral treatment he developed disseminated Talaromyces marneffei infection and was treated with intravenous amphotericin B. Despite this treatment, he presented with bilateral granulomatous anterior uveitis...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1657468

    authors: Khieu C,Apivatthakakul A,Kunavisarut P,Pathanapitoon K

    更新日期:2020-10-02 00:00:00

  • Cryptococcal chorioretinitis with immune reconstitution inflammatory syndrome.

    abstract::Immune Reconstitution Inflammatory Syndrome (IRIS) is an inflammatory syndrome in the context of immune restoration directed at a specific infectious antigen despite resolution of infection, often associated with opportunistic infections. IRIS has been reported in 30% to 35% of HIV patients who have cryptococcosis in ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273940903003505

    authors: Shulman J,de la Cruz EL,Latkany P,Milman T,Iacob C,Sanjana V

    更新日期:2009-09-01 00:00:00

  • Corneal Graft Rejection after Yellow Fever Vaccine: A Case Report.

    abstract::Purpose: To report an unusual case of corneal graft rejection after yellow fever vaccine. Methods: Case report. Results: We have described the case of a 48-year-old man who developed a corneal graft rejection in the left eye 3 weeks after a yellow fever vaccination. The ophthalmic examination of the left eye revealed ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2020.1870146

    authors: Vignapiano R,Vicchio L,Favuzza E,Cennamo M,Mencucci R

    更新日期:2021-01-28 00:00:00

  • Ophthalmic Shingles with Simultaneous Acute Retinal Necrosis in the Opposite Eye.

    abstract:PURPOSE:To report a case of acute retinal necrosis (ARN) occurring in the opposite eye to the ophthalmic shingles eruption. DESIGN:Case report. METHODS:Clinical examination and multimodal imaging review, including ultra-widefield photography and fluorescein angiography (FA). RESULTS:A 49-years-old man attended the U...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2020.1770298

    authors: Battista M,Marchese A,Bordato A,Bandello F,Modorati GM,Miserocchi E

    更新日期:2020-07-09 00:00:00

  • Orbital sarcoidosis manifesting with enophthalmos.

    abstract:PURPOSE:To describe a case of orbital sarcoidosis manifesting with enophthalmos. METHODS:A 60-year-old woman presented with right enophthalmos. She had a palpable mass in her anterior orbit inferiorly. She underwent a complete ophthalmic evaluation, magnetic resonance imaging, and histopathologic examination. RESULTS...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940601038589

    authors: Attia S,Zaouali S,Jeguirim H,Njim L,Kriaa S,Yahia SB,Khairallah M

    更新日期:2006-12-01 00:00:00

  • Polymerase chain reaction for diagnosis of herpetic intraocular inflammation.

    abstract::The authors present a polymerase chain reaction method for rapid and direct diagnosis of herpetic intraocular infections using small volume samples of intraocular fluid from 29 patients with various intraocular inflammatory diseases and 24 controls with senile cataract. Of six patients with early acute retinal necrosi...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273949309086545

    authors: Usui M,Usui N,Goto H,Minoda H,Rai T

    更新日期:1993-01-01 00:00:00

  • Use of a high infusion rate to prevent posterior dislocation of fluocinolone acetonide implant during surgical removal.

    abstract:PURPOSE:To describe a strategy for reducing the risk of posterior dislocation of a fluocinolone implant during exchange or removal. DESIGN:Case report and in vitro model. METHODS:Description of a surgical case and an in vitro experiment evaluating the role of infusion pressure in maintaining implant stability in surg...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2011.553980

    authors: Wan W,Stewart JM

    更新日期:2011-06-01 00:00:00

  • Association Study of ARMC9 Gene Variants with Vogt-Koyanagi-Harada Disease in Japanese Patients.

    abstract::Purpose: To investigate whether variants in the ARMC9 gene encoding KU-MEL-1 are associated with Vogt-Koyanagi-Harada (VKH) disease in a Japanese population. Methods: We recruited 380 Japanese patients with VKH disease and 744 Japanese healthy controls to genotype seven single-nucleotide polymorphisms (SNPs) in ARMC9....

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2018.1523438

    authors: Ohno T,Meguro A,Takeuchi M,Yamane T,Teshigawara T,Kitaichi N,Horie Y,Namba K,Ohno S,Nakao K,Sakamoto T,Sakai T,Nakano T,Keino H,Okada AA,Takeda A,Fukuhara T,Mashimo H,Ohguro N,Oono S,Enaida H,Okinami S,Mizuki

    更新日期:2019-01-01 00:00:00

  • Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) - Report 2: Pattern of Uveitis Investigations in Singapore.

    abstract::Purpose: To analyze the pattern of laboratory investigations of uveitis at a tertiary referral eye care center in Singapore.Methods: Retrospective analysis of 2040 uveitis cases from the Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) database over a 12-year period (2004 - 2015).Results: Patients with...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2018.1535080

    authors: Low R,Chen EJ,Bin Ismail MA,Mi H,Ling HS,Lim WK,Teoh SC,Agrawal R

    更新日期:2020-01-01 00:00:00

  • Mucormycosis Endophthalmitis in a Silicone Oil-Filled Eye of an Immunocompetent Patient.

    abstract::Purpose:: Fungal endophthalmitis following pars plana vitrectomy with silicone oil tamponade is an infrequent entity. Filamentous fungi like aspergillus are generally associated with endophthalmitis. Mucor is a rarely implicated pathogen in cases of endophthalmitis with only two reported cases in medical literature. B...

    journal_title:Ocular immunology and inflammation

    pub_type: 信件

    doi:10.1080/09273948.2018.1518462

    authors: Dogra M,Bhutani G,Gupta V

    更新日期:2019-01-01 00:00:00

  • Stromelysin (matrix metalloproteinase-3) and tissue inhibitor of metalloproteinase (TIMP-1) mRNA expression in scleritis.

    abstract::Scleritis is a severe and destructive inflammatory eye disease characterized by extensive extracellular matrix degradation. As in rheumatoid arthritis (RA), tissue destruction in scleritis may be mediated in part by matrix metalloproteinases such as collagenase (MMP-1) and stromelysin (MMP-3) which are normally kept i...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273949509069111

    authors: Girolamo ND,McCluskey PJ,Lloyd A,Wakefield D

    更新日期:1995-01-01 00:00:00

  • The Emerging Challenge of Diagnosing Drug-resistant Tubercular Uveitis: Experience of 110 Eyes from North India.

    abstract::Background: Rapid and timely diagnosis of tubercular uveitis (TBU) is of paramount importance to save these eyes from blindness. The present study was, therefore, undertaken to carry out a comparative evaluation of Gene Xpert MTB/RIF (Xpert), MTBDRplus and Multiplex PCR (MPCR) for the diagnosis of TBU. These tests wer...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1655581

    authors: Sharma K,Gupta A,Sharma M,Sharma A,Bansal R,Sharma SP,Singh RD,Gupta V

    更新日期:2019-10-03 00:00:00

  • Application of Laser Flare Photometry in the Quantification of Blood-Aqueous Barrier Breakdown after Micro-incision Vitrectomy.

    abstract::Purpose: The purpose of the study is to quantify aqueous flare using laser flare photometry (LFM) in patients undergoing 25-G pars plana vitrectomy (PPV) and assess the need for postoperative topical corticosteroid administration . Methods: Prospective evaluation of 50 eyes (50 patients) was performed using LFM until ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2018.1449867

    authors: Agarwal A,Joshi D,Katoch D,Aggarwal K,Singh R,Gupta V

    更新日期:2019-01-01 00:00:00

  • Indocyanine green and fundus fluorescein angiographic findings in patients with active ocular Behcet's disease.

    abstract:PURPOSE:To define the indocyanine green (ICG) and fundus fluorescein angiographic (FFA) features of Behçet's disease. METHODS:The study included 49 eyes of 25 patients (19 males, 6 females; mean age: 34.1 years; age range: 14-68 years) with Behçet's disease and active ocular involvement that fulfilled the criteria of ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940490518757

    authors: Gedik S,Akova Y,Yilmaz G,Bozbeyoğlu S

    更新日期:2005-02-01 00:00:00

  • Ocular Involvement in Muckle-Wells Syndrome.

    abstract::Purpose: To present the ocular findings of the members of a family that has the diagnosis of Muckle Wells syndrome, a form of cryopyrin associated periodic syndrome (CAPS).Materials and Methods: Nine patients with MWS were included in this study. Each study participant underwent a systemic evaluation, comprehensive op...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2018.1552305

    authors: Cekic S,Yalcinbayir O,Kilic SS

    更新日期:2020-01-01 00:00:00

  • Antigen-presenting cells are targets of regulatory T cells similar to those that mediate anterior chamber-associated immune deviation.

    abstract:PURPOSE:To identify the means by which in-vitro-generated regulatory T cells, similar to those in anterior chamber-associated immune deviation (ACAID), suppress antigen-specific T-cell responses. METHODS:T regulators (T regs), generated by stimulating ovalbumin (OVA)-specific Tcr transgenic DO11.10 T cells with OVA-pu...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940490895317

    authors: Yokoi H,Streilein JW

    更新日期:2004-06-01 00:00:00

  • Uveitis referral pattern in a Midwest University Eye Center.

    abstract::We determined the referral pattern and visual prognosis for patients with uveitis at a tertiary university eye center in the Midwestern U.S. over a five-year period. A retrospective chart review was conducted on 853 patients seen in the Department of Ophthalmology and Visual Sciences (DOVS) at Washington University an...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1076/ocii.11.4.287.18270

    authors: Oruc S,Kaplan AD,Galen M,Kaplan HJ

    更新日期:2003-12-01 00:00:00

  • Evaluation of the Anterior Segment Parameters of the Patients with Scleroderma.

    abstract:PURPOSE:To evaluate corneal parameters of scleroderma (SC) patients by Pentacam-HR. METHODS:Twenty-two eyes of 22 SC patients and 33 eyes of 33 control subjects were enrolled. All participants underwent Pentacam (Pentacam-HR, Oculus, Germany) evaluation. Both SC and control groups were divided into two subgroups as dr...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2015.1115079

    authors: Şahin M,Yüksel H,Şahin A,Cingü AK,Türkcü FM,Kaya S,Yazmalar L,Batmaz İ

    更新日期:2017-04-01 00:00:00

  • Effect of Allergic Diseases on Keratoconus Severity.

    abstract:PURPOSE:To investigate the association between keratoconus (KC) and allergic diseases. METHODS:In a prospective age- and sex-matched case--control study clinical data of 885 KC patients and 1526 controls were evaluated regarding the presence of various allergic diseases. Severity of KC and ophthalmic parameters of KC ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2016.1145697

    authors: Naderan M,Rajabi MT,Zarrinbakhsh P,Bakhshi A

    更新日期:2017-06-01 00:00:00

  • Can we be more objective in determining the response to treatment in uveitis patients aside from recording anterior chamber reaction?

    abstract::Several subjective and arbitrary grading methods are used in assessing cell and flare in uveitis. Clinicians are in need of an objective method of determining and monitoring active inflammation. We studied the correlation of changes in macular thickness between the visits and compared the change to visual acuity (VA),...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940802702587

    authors: Akduman L

    更新日期:2009-07-01 00:00:00

  • Tachykinins as enhancers of prostaglandin E2-induced intraocular inflammation.

    abstract::The effects of tachykinins on prostaglandin E2 (PGE2)-induced intraocular inflammation were investigated. PGE2 (0.01% or 0.1%) instillation induced iridal hyperemia and protein leakage into the aqueous humor in rabbits, but caused minimal miosis. Intravitreally injected substance P (SP) or neurokinin A (NKA), on the o...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1076/ocii.6.1.19.8080

    authors: Tsuji F,Hamada M,Shirasawa E

    更新日期:1998-03-01 00:00:00

  • Ipilimumab-induced Ocular and Orbital Inflammation--A Case Series and Review of the Literature.

    abstract:PURPOSE:Ipilimumab, a monoclonal antibody directed against the immune protein cytotoxic T-lymphocyte antigen-4 (CTLA-4), characteristically induces side effects called "immune-related adverse events" (IRAE). Although ophthalmic involvement is rare, we report 7 cases of eye and orbit complications related to ipilimumab ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:10.3109/09273948.2014.1001858

    authors: Papavasileiou E,Prasad S,Freitag SK,Sobrin L,Lobo AM

    更新日期:2016-01-01 00:00:00

  • Rubella-related intermediate uveitis in pregnancy--a rare presentation.

    abstract:PURPOSE:To report a rare case of intermediate uveitis following rubella infection in pregnancy. DESIGN:Case report. METHODS:A 35-year-old pregnant woman, at 24 weeks of gestation, presented with sudden floaters and blurring of vision of the left eye. Ocular examination revealed vitritis 1-2+ with no retinal involveme...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2011.555593

    authors: Thirupathy A,Tajunisah I

    更新日期:2011-06-01 00:00:00

  • Indicators of Post-Operative Intraocular Pressure Elevation after Naïve Fluocinolone Acetonide Surgical Implantation.

    abstract:PURPOSE:To determine factors conferring an increased risk of developing ocular hypertension secondary to the fluocinolone acetonide (FA) sustained-release surgical implant (Retisert). DESIGN:Retrospective, observational case series. METHODS:Patients with a history of chronic noninfectious posterior uveitis undergoing...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1624778

    authors: Sadowsky AJ,Pecen PE,Feinstein E,Palestine AG

    更新日期:2020-07-03 00:00:00

  • Cytomegalovirus retinitis in immunocompetent patients: case reports and literature review.

    abstract:PURPOSE:The purpose of this study was to examine 2 cases of cytomegalovirus (CMV) retinitis, occuring in 2 immunocompentent adult patients. METHODS:Case selection and literature review. RESULTS:Both patients cited significantly decreased vision despite systemic, topical, and/or local corticosteroid use. Neither patie...

    journal_title:Ocular immunology and inflammation

    pub_type: 信件,评审

    doi:10.3109/09273948.2013.786095

    authors: Radwan A,Metzinger JL,Hinkle DM,Foster CS

    更新日期:2013-08-01 00:00:00

  • Regional Differences in the Clinical Manifestation of Ocular Toxoplasmosis Between the Center and Northeast of Argentina.

    abstract::Purpose: To compare the clinical characteristics of patients with active episodes of ocular toxoplasmosis from three provinces, Misiones, Santa Fe, and Buenos Aires, Argentina. Methods: Patients with a diagnosis of ocular toxoplasmosis from three databases of four tertiary referral uveitis centers were reviewed. Colle...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2018.1484494

    authors: Schlaen A,Colombero D,Ormaechea S,Ladeveze E,Rudzinski C,Ingolotti M,Couto C,Rudzinski M

    更新日期:2019-01-01 00:00:00

  • Distinguishing Microvasculature Features of Vogt-Koyanagi-Harada in Patients in Acute and Convalescent Phases Using Optical Coherence Tomography Angiography.

    abstract::Purpose: To evaluate retinal and choroidal microvascular features of VKH patients in acute and convalescent phases after treatment using OCTA.Methods: A prospective, observational study was conducted in patients with initial VKH at the acute stage (n = 15) and healthy participants (n = 15) served as controls. After 3-...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1695856

    authors: Luo K,Cai H,Hu Y,Jin C,Gan X,Deng Y,Lu M,Chen H,Su L,Chen G,Chi W

    更新日期:2020-01-03 00:00:00

  • Medical Therapy of Uveitic Macular Edema: Biologic Agents.

    abstract::Introduction: Uveitic macular edema (UME) is a significant cause of visual impairment in all uveitis types. Methods: Reports that were cited in the MEDLINE database, that analyzed the effectiveness of biologics for UME in at least five patients, with a minimum follow-up of 3 months, published prior to April 1, 2019 we...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1709648

    authors: Radosavljevic A,Agarwal M,Bodaghi B,Smith JR,Zierhut M

    更新日期:2020-11-16 00:00:00

  • Immunopathology of Virus-Induced Anterior Uveitis.

    abstract::Herpes simplex virus, varicella zoster virus, human cytomegalovirus, and rubella virus are the most common causes of virus-induced anterior uveitis. They can present in a variety of entities not only with typical but also overlapping clinical characteristics. These viral infections are commonly associated with ocular ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:10.1080/09273948.2018.1439069

    authors: De Groot-Mijnes JDF,Chan ASY,Chee SP,Verjans GMGM

    更新日期:2018-01-01 00:00:00

  • Mycophenolate mofetil in the therapy of uveitic macular edema--long-term results.

    abstract:PURPOSE:To assess the long-term efficacy of mycophenolate mofetil (MMF) in uveitic cystoid macular edema (CMO). METHODS:Thirty-eight uveitis patients with CMO treated with MMF with a follow-up of at least 5 years were analyzed. The patients were divided into two groups: group A, 24 patients with CMO that had occurred ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2012.665562

    authors: Doycheva D,Zierhut M,Blumenstock G,Stuebiger N,Deuter C

    更新日期:2012-06-01 00:00:00