Current Practices in Ocular Toxoplasmosis: A Survey of Brazilian Uveitis Specialists.

Abstract:

PURPOSE:To describe treatment practices for ocular toxoplasmosis among members of the Brazilian Uveitis Society. METHODS:An online questionnaire sent to specialists, between October 2014 and March 2015. RESULTS:Most respondents (67.9%) treat all active cases. Most specialists consider visual acuity <20/200 (88.2%), severe vitreous inflammation (94.1%), and ocular disease during acquired infection (88.2%) as absolute indications for treatment. Systemic steroids are associated with anti-toxoplasmic therapy in most cases by 50.9% of the respondents. For immunocompetent individuals, 57.4% of the respondents chose trimethoprim/sulfamethoxazole. Classical therapy (sulfadiazine/pyrimethamine) is preferred most for patients with central lesions (70.4%), immunosuppression (68.4%), acquired infection (70.4%), and atypical forms (74.1%). For patients with frequent relapses, 84.9% of the respondents preferred antibiotic prophylaxis. CONCLUSIONS:Treatment patterns of ocular toxoplasmosis are not uniform among Brazilian specialists. Most specialists treat all cases of active retinochoroiditis. Typical cases are more frequently treated with trimethoprim/sulfamethoxazole. However, classical therapy is the regimen of choice when lesions are considered more severe.

journal_name

Ocul Immunol Inflamm

authors

Morais FB,Arantes TEFE,Muccioli C

doi

10.1080/09273948.2016.1215471

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

317-323

issue

2

eissn

0927-3948

issn

1744-5078

journal_volume

26

pub_type

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