Clinical Characteristics of Primary Vitreoretinal Lymphoma in an Indian Population.

Abstract:

PURPOSE:Primary vitreoretinal lymphomas (PVRL) pose a major diagnostic challenge, especially in the countries with a high prevalence of infectious variety of uveitis. The present study aims to report the clinical characteristics and diagnostic difficulties in patients with PVRL in an Indian Population. METHODS:Retrospective chart reviews of 12 patients with a diagnosis of PVRL. RESULTS:The study included 6 men and 6 women, with a mean age of 55.66 ± 8.76 years. All had bilateral disease. The clinical signs included anterior uveitis (12 eyes; 50.0%); vitritis (18 eyes; 75%); vitreous clumps (16 eyes; 66.6%); subretinal deposits (11 eyes; 45.8%); retinal vasculitis (6 eyes; 25%); and optic disc swelling (2 eyes; 8.3%). The most commonly mistaken diagnosis was intraocular tuberculosis. The intraocular lesions responded to multiple intravitreal methotrexate injections. CONCLUSIONS:PVRL in India was likely to be mistaken for an infectious variety of uveitis. A high index of suspicion and thorough clinical examination is necessary to make the diagnosis.

journal_name

Ocul Immunol Inflamm

authors

Mahajan S,Nijhawan R,Rajwanshi A,Karkhur S,Mulkutar S,Dogra M,Lal V,Gupta V,Gupta A

doi

10.3109/09273948.2016.1139731

subject

Has Abstract

pub_date

2017-10-01 00:00:00

pages

633-638

issue

5

eissn

0927-3948

issn

1744-5078

journal_volume

25

pub_type

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