Clinical study on patients with Behçet's disease in Hokkaido.

Abstract:

:Behçet's disease is the most frequently encountered form of endogenous uveitis in Japan. The authors examined the clinical manifestations in cases with Behçet's disease over six years (1987-1992), and compared the results with those of a previous study (1978-1983). In the more recent study the number of new patients who visited our clinic was 54, compared to 180 in the previous study. As for the frequencies of the four major symptoms in the recent study, oral aphtha were seen in 100%, skin lesions in 88.9%, ocular lesions in 74.0%, and genital ulcers in 61.1% of the patients. The frequencies of these major symptoms were not significantly different between the two time periods investigated. Analysis of the type of ocular involvement showed that 94.4% of the patients in the more recent study belonged to the uveoretinitis type and 5.6% of the patients belonged to the iridocyclitis type, whereas in the previous study the figures were 71.5% and 28.5%, respectively. The ratio of the patients with severe eye involvement has increased recently. However the visual prognosis of patients was better in the more recent study than in the previous study. In the previous study a marked decrease in visual acuity was observed during a two-year follow-up, whereas in the 1987-1992 period it was observed that visual acuity hardly changed over two years. The observed improvement in the visual prognosis may be due to the fact that the treatment of Behçet's disease has become more effective in recent years.

journal_name

Ocul Immunol Inflamm

authors

Kotake S,Furudate N,Sasamoto Y,Yoshikawa K,Okamoto T,Goda C,Matsuda H

doi

10.3109/09273949509069117

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

237-42

issue

4

eissn

0927-3948

issn

1744-5078

journal_volume

3

pub_type

杂志文章
  • Outcomes of treatment with immunomodulatory therapy in patients with corticosteroid-resistant juvenile idiopathic arthritis-associated chronic iridocyclitis.

    abstract:PURPOSE:To describe the clinical outcome of patients with juvenile idiopathic arthritis (IA)-associated chronic iridocyclitis unresponsive to conventional therapy, in whom inflammation was eventually controlled using immunomodulatory therapy (IMT), and to determine if patients treated early with IMT have better visual ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940590951061

    authors: Yu EN,Meniconi ME,Tufail F,Baltatzis S,Foster CS

    更新日期:2005-09-01 00:00:00

  • Immune deviation and ocular infections with varicella zoster virus.

    abstract::Since experimental, herpes simplex virus-induced acute retinal necrosis (ARN) develops in mice only if the mice fail to acquire virus-specific delayed hypersensitivity (DH) and despite their production of anti-viral antibodies (i.e. ACAID), I investigated whether a similar situation exists for patients with either var...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1076/ocii.12.1.17.28066

    authors: Kezuka T

    更新日期:2004-03-01 00:00:00

  • Multimodal Imaging in Ocular Sarcoidosis.

    abstract::Aim: Ocular sarcoidosis presents a diagnostic challenge because of its varied clinical presentations. It is important to distinguish sarcoidosis from other uveitis diseases. Multimodal imaging provides useful data to be introduced into clinical practice. Methods: This is a review article. Conclusions: This review arti...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2020.1751210

    authors: Mahendradas P,Maruyama K,Mizuuchi K,Kawali A,Kitaichi N

    更新日期:2020-11-16 00:00:00

  • Features of Retinitis-like Lesions in Vitreoretinal Lymphoma.

    abstract::Purpose: To describe the distinguishing features of retinitis-like lesions seen in vitreoretinal lymphoma (VRL) from viral and toxoplasma retinitis. Methods: In this multicenter, retrospective study, we reviewed charts and imaging of consecutive patients with VRL. The associated features and the characteristics of ret...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1648835

    authors: Marchese A,Agarwal A,Miserocchi E,Giuffrè C,Bandello F,Modorati G,Prakash G,Gupta N,Bosello F,Sharma SP,Gupta V

    更新日期:2019-09-30 00:00:00

  • Ocular Behçet's Disease: Changing Patterns Over Time, Complications and Long-Term Visual Prognosis.

    abstract:PURPOSE:To investigate demographic, clinical features and complications of Italian patients with ocular Behçet's disease (BD) over time. METHODS:Retrospective study of 385 patients examined from 1968 to 2011, 265 of whom had follow-up ≥ 12 months. RESULTS:A significant increase in the proportion of females (p = 0.03)...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2015.1094095

    authors: Accorinti M,Pesci FR,Pirraglia MP,Abicca I,Pivetti-Pezzi P

    更新日期:2017-02-01 00:00:00

  • Multimodal Imaging of Post-Infectious Unilateral Outer Retinopathy and Choroiditis.

    abstract::Purpose: To describe with multimodal imaging a case of post-infectious unilateral outer retinopathy with choroiditis. Methods: Retrospective chart review of a case of a 67-year old male who presented following the onset of viral symptoms with an acute onset outer retinopathy, small vessel leakage on fluorescein angiog...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2018.1485954

    authors: Kodati S,Gangaputra S,Sen HN

    更新日期:2019-01-01 00:00:00

  • Association Study of ARMC9 Gene Variants with Vogt-Koyanagi-Harada Disease in Japanese Patients.

    abstract::Purpose: To investigate whether variants in the ARMC9 gene encoding KU-MEL-1 are associated with Vogt-Koyanagi-Harada (VKH) disease in a Japanese population. Methods: We recruited 380 Japanese patients with VKH disease and 744 Japanese healthy controls to genotype seven single-nucleotide polymorphisms (SNPs) in ARMC9....

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2018.1523438

    authors: Ohno T,Meguro A,Takeuchi M,Yamane T,Teshigawara T,Kitaichi N,Horie Y,Namba K,Ohno S,Nakao K,Sakamoto T,Sakai T,Nakano T,Keino H,Okada AA,Takeda A,Fukuhara T,Mashimo H,Ohguro N,Oono S,Enaida H,Okinami S,Mizuki

    更新日期:2019-01-01 00:00:00

  • Subretinal fibrosis and uveitis syndrome in a patient with ectodermal dysplasia.

    abstract:PURPOSE:To report a case of subretinal fibrosis and uveitis syndrome in association with ectodermal dysplasia. METHODS:Chart review of a patient with subretinal fibrosis and uveitis syndrome and ectodermal dysplasia. RESULTS:The authors identified one case of a patient with the diagnoses of subretinal fibrosis and uv...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273940903168670

    authors: Huffman RI,Huang JJ

    更新日期:2009-09-01 00:00:00

  • Outcomes of cataract surgery in ocular cicatricial pemphigoid.

    abstract:PURPOSE:To report the outcomes of cataract surgery in ocular cicatricial pemphigoid (OCP). SETTING:L. V. Prasad Eye Institute, Hyderabad, India. DESIGN:Retrospective, interventional case series. METHODS:Patients diagnosed with OCP who had undergone cataract surgery were included. Staging of disease, type of surgery,...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2013.819106

    authors: Puranik CJ,Murthy SI,Taneja M,Sangwan VS

    更新日期:2013-12-01 00:00:00

  • Tear secretory IgA: evaluation of usefulness as a diagnostic marker in herpetic keratitis.

    abstract::In a South Indian study, an 'in-house' enzyme-linked immunosorbent assay (ELISA) was developed to evaluate the potential of herpes simplex virus (HSV)-specific tear secretory IgA (sIgA) in the diagnosis of herpes simplex keratitis (HSK). The presence of HSV-specific tear sIgA was found to be diagnostic in 20.28% of ca...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1076/ocii.7.2.61.4023

    authors: Pramod NP,Dhevahi E,Sudhamathi K,Kannan K,Thyagarajan SP

    更新日期:1999-06-01 00:00:00

  • Topical podophyllum-induced toxic anterior uveitis.

    abstract:OBJECTIVE:To report a case of toxic anterior uveitis probably secondary to the use of topical podophyllum. DESIGN:Case report, interventional. METHODS:The authors present a 78-year-old male with acute anterior uveitis that developed within a couple of hours of application of topical podophyllum. In vivo confocal micr...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2010.551446

    authors: Avadhani K,Mahendradas P,Shetty R,Shetty BK

    更新日期:2011-04-01 00:00:00

  • Inflammatory Papillitis in Uveitis: Response to Treatment and Use of Optic Nerve Optical Coherence Tomography for Monitoring.

    abstract:PURPOSE:To describe the clinical course of uveitis-associated inflammatory papillitis and evaluate the utility and reproducibility of optic nerve spectral domain optical coherence tomography (SD-OCT). METHODS:Data on 22 eyes of 14 patients with uveitis-related papillitis and optic nerve imaging were reviewed. SD-OCT m...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2014.991041

    authors: Cho H,Pillai P,Nicholson L,Sobrin L

    更新日期:2016-01-01 00:00:00

  • Application of Laser Flare Photometry in the Quantification of Blood-Aqueous Barrier Breakdown after Micro-incision Vitrectomy.

    abstract::Purpose: The purpose of the study is to quantify aqueous flare using laser flare photometry (LFM) in patients undergoing 25-G pars plana vitrectomy (PPV) and assess the need for postoperative topical corticosteroid administration . Methods: Prospective evaluation of 50 eyes (50 patients) was performed using LFM until ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2018.1449867

    authors: Agarwal A,Joshi D,Katoch D,Aggarwal K,Singh R,Gupta V

    更新日期:2019-01-01 00:00:00

  • Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) - Report 2: Pattern of Uveitis Investigations in Singapore.

    abstract::Purpose: To analyze the pattern of laboratory investigations of uveitis at a tertiary referral eye care center in Singapore.Methods: Retrospective analysis of 2040 uveitis cases from the Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) database over a 12-year period (2004 - 2015).Results: Patients with...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2018.1535080

    authors: Low R,Chen EJ,Bin Ismail MA,Mi H,Ling HS,Lim WK,Teoh SC,Agrawal R

    更新日期:2020-01-01 00:00:00

  • A comparison of heparin-coated and uncoated intraocular lenses in glaucoma patients undergoing combined cataract extraction and trabeculectomy and in diabetic patients undergoing cataract extraction.

    abstract::The postoperative course of cataract extraction and IOL implantation combined with trabeculectomy in glaucoma patients and of cataract extraction with intraocular lens (IOL) in diabetic patients is more complicated than that of cataract extraction with IOL implantation in otherwise healthy eyes. The main complications...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273949309057057

    authors: Zalish M,Rahmiel R,Pollack A,Milstein A,Oliver M

    更新日期:1993-01-01 00:00:00

  • Analysis of retinal findings of acute retinal necrosis using optical coherence tomography.

    abstract:PURPOSE:To analyze the retinal findings in patients with ARN, optical coherence tomography (OCT) was performed. METHODS:Seven patients (7 eyes) with ARN were studied using OCT. RESULTS:OCT images depicted highly reflective areas in the inner layers of the retina in all seven cases, corresponding with the yellowish-wh...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940600672198

    authors: Suzuki J,Goto H,Minoda H,Iwasaki T,Sakai J,Usui M

    更新日期:2006-06-01 00:00:00

  • Autoimmune retinopathy in a patient with autoimmune polyendocrine syndrome type I.

    abstract:PURPOSE:To present a case of autoimmune retinopathy resulting from a mutation in the autoimmune regulator (AIRE) gene. DESIGN:Case study. METHODS:Case review. RESULTS:Mild improvement of goldmann visual field following treatment with systemic and local immunosuppression. CONCLUSIONS:There are a limited number of ca...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2012.754906

    authors: Breunig A,Lee MS,Miller BS,Binstadt BA,Anderson MS,Montezuma S

    更新日期:2013-04-01 00:00:00

  • Multimodal Evaluation of Presumed Tuberculous Serpiginous-Like Choroiditis.

    abstract::Purpose: To evaluate multimodal imaging findings in longitudinal follow-up of a patient with presumed tuberculous serpiginous-like choroiditis (TB-SLC). Method: We evaluated multimodal imaging in a 62-year-old male with TB-SLC. Correlation between optical coherence tomography angiography (OCTA), swept-source OCT (SS-O...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2018.1501497

    authors: Wang H,Tan SZ,Aslam T,Jones NP,Steeples LR

    更新日期:2019-01-01 00:00:00

  • Use of a high infusion rate to prevent posterior dislocation of fluocinolone acetonide implant during surgical removal.

    abstract:PURPOSE:To describe a strategy for reducing the risk of posterior dislocation of a fluocinolone implant during exchange or removal. DESIGN:Case report and in vitro model. METHODS:Description of a surgical case and an in vitro experiment evaluating the role of infusion pressure in maintaining implant stability in surg...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2011.553980

    authors: Wan W,Stewart JM

    更新日期:2011-06-01 00:00:00

  • Visual loss associated with rickettsial disease.

    abstract:UNLABELLED:Abstract Purpose: To characterize and analyze ocular involvement associated with visual loss in a cohort of patients with rickettsial disease. METHODS:Retrospective study of 16 eyes of 14 patients. RESULTS:Mean initial visual acuity (VA) was 20/63 (range, 20/800-20/25). White retinal lesions infiltrating i...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2013.848907

    authors: Kahloun R,Gargouri S,Abroug N,Sellami D,Ben Yahia S,Feki J,Khairallah M

    更新日期:2014-10-01 00:00:00

  • Drug therapy in Behçet's disease.

    abstract::Behçet's disease is one of the most difficult forms of uveitis to treat. Variety in disease presentation and severity, as well as regional differences in standard of care, demand a tailor-made approach. Anterior segment inflammation generally responds to topical corticosteroids. However, the onset of posterior segment...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:

    authors: Okada AA

    更新日期:2000-06-01 00:00:00

  • Characteristics of Cytomegalovirus Uveitis in Immunocompetent Patients.

    abstract:PURPOSE:To present the clinical characteristics of patients with anterior uveitis who had evidence of cytomegalovirus (CMV) infection on polymerase chain reaction PCR-based assays for viral DNA in aqueous samples. METHODS:This was a retrospective observational case series of 16 patients with CMV infection on qualitati...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2014.950384

    authors: Woo JH,Lim WK,Ho SL,Teoh SC

    更新日期:2015-01-01 00:00:00

  • Anti-Inflammatory Effect of Dehydroxymethylepoxyquinomicin, a Nuclear factor-κB Inhibitor, on Endotoxin-Induced Uveitis in Rats In vivo and In vitro.

    abstract::Purpose: To determine the anti-inflammatory effects of dehydroxymethylepoxyquinomicin (DHMEQ), a nuclear factor-κB (NF-κB) inhibitor, on endotoxin-induced uveitis (EIU) in rats.Methods: EIU was induced by a subcutaneous injection of lipopolysaccharide (LPS) in Lewis rats. DHMEQ was injected intraperitoneally concurren...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1568502

    authors: Ando Y,Keino H,Kudo A,Hirakata A,Okada AA,Umezawa K

    更新日期:2020-01-01 00:00:00

  • The Role of Dexamethasone Implant in the Management of Tubercular Uveitis.

    abstract:PURPOSE:To study the safety and efficacy of intravitreal injection of dexamethasone implant in the management of posterior segment involvement in tubercular uveitis (TBU). METHODS:In this study, retrospective analysis of safety and efficacy of intravitreal injection of dexamethasone implant for various indications suc...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2017.1400074

    authors: Agarwal A,Handa S,Aggarwal K,Sharma M,Singh R,Sharma A,Agrawal R,Sharma K,Gupta V

    更新日期:2018-01-01 00:00:00

  • Clinical Course and Outcomes of Pediatric Tubercular Uveitis in North India.

    abstract:PURPOSE:To analyze the clinical features, course, management, and outcomes of tubercular (TB) uveitis in the pediatric population and assess the response to anti-tubercular therapy (ATT). METHODS:Hospital records of children (≤16 years) from a large tertiary-care institute between January 2001 and December 2015 were r...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2017.1296579

    authors: Kaur S,Aggarwal K,Agarwal A,Suri D,Gupta A,Singh R,Bansal R,Singh S,Singh N,Gupta A,Gupta V

    更新日期:2018-01-01 00:00:00

  • Acute posterior multifocal placoid pigment epitheliopathy following mumps.

    abstract:PURPOSE:Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is an acquired inflammatory disorder affecting the retina, retinal pigment epithelium, and choroid of healthy adults. APMPPE has been reported to occur after diverse infectious diseases, suggesting a possible immune disorder. The primary site of...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1076/ocii.6.3.189.4038

    authors: Borruat FX,Piguet B,Herbort CP

    更新日期:1998-09-01 00:00:00

  • Polymerase chain reaction for diagnosis of herpetic intraocular inflammation.

    abstract::The authors present a polymerase chain reaction method for rapid and direct diagnosis of herpetic intraocular infections using small volume samples of intraocular fluid from 29 patients with various intraocular inflammatory diseases and 24 controls with senile cataract. Of six patients with early acute retinal necrosi...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273949309086545

    authors: Usui M,Usui N,Goto H,Minoda H,Rai T

    更新日期:1993-01-01 00:00:00

  • Collagen Cross-Linking in the Management of Microbial Keratitis.

    abstract::Increasing resistance to antimicrobial agents has contributed to an elevated risk of complications of infectious keratitis. Corneal collagen cross-linking (CXL) has been widely adopted for the management of keratoconus and post-refractive surgery corneal ectasia. It has recently been introduced as an option for treati...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:10.1080/09273948.2017.1414856

    authors: Bonzano C,Di Zazzo A,Barabino S,Coco G,Traverso CE

    更新日期:2019-01-01 00:00:00

  • Cytomegalovirus: virological facts for clinicians.

    abstract::Human cytomegalovirus (HCMV) is a complex DNA virus encoding more than 200 viral proteins. This highly adapted opportunist agent has developed several ways to evade the immune system. Among all clinical features due to HCMV, retinitis occurs especially in severely immunosuppressed patients, particularly during the end...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:10.1076/ocii.7.3.133.3998

    authors: Bodaghi B,Michelson S

    更新日期:1999-12-01 00:00:00

  • Comparative Analysis of Anterior Chamber Flare Grading between Clinicians with Different Levels of Experience and Semi-automated Laser Flare Photometry.

    abstract:PURPOSE:To assess correlation for anterior chamber flare grading between clinicians with different levels of experience and with semi-automated flare reading in a cohort of patients with heterogeneous uveitic entities. METHODS:Fifty-nine observations from 36 patients were recorded and analyzed for statistical associat...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2014.990042

    authors: Agrawal R,Keane PA,Singh J,Saihan Z,Kontos A,Pavesio CE

    更新日期:2016-01-01 00:00:00