Long-term Efficacy of Interferon in Severe Uveitis Associated with Behçet Disease.

abstract：:Purpose: To compare vessel density (VD) as measured by optical coherence tomography angiography (OCTA), in uveitic eyes with secondary glaucoma (UG) with VD in uveitic eyes without glaucoma (UV), eyes with primary open-angle glaucoma (POAG), and healthy eyes (HY). Methods: VD was measured at the following segmentation...

journal_title：Ocular immunology and inflammation

authors： Lommatzsch C,Bauermann P,Heimes-Bussmann B,Nolte C,Heinz C

更新日期：2020-11-13 00:00:00

abstract：PURPOSE:To report the outcomes of cataract surgery in ocular cicatricial pemphigoid (OCP). SETTING:L. V. Prasad Eye Institute, Hyderabad, India. DESIGN:Retrospective, interventional case series. METHODS:Patients diagnosed with OCP who had undergone cataract surgery were included. Staging of disease, type of surgery,...

journal_title：Ocular immunology and inflammation

authors： Puranik CJ,Murthy SI,Taneja M,Sangwan VS

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:To examine the role of interleukin 27(IL-27) and interleukin 35 (IL-35) in diabetic retinopathy (DR). METHODS:Patients with diabetes mellitus were divided into three groups: diabetes without retinopathy (DWR), non-proliferative diabetic retinopathy (NPDR), and proliferative diabetic retinopathy (PDR). Patients...

journal_title：Ocular immunology and inflammation

authors： Yan A,You H,Zhang X

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:To describe a case of orbital sarcoidosis manifesting with enophthalmos. METHODS:A 60-year-old woman presented with right enophthalmos. She had a palpable mass in her anterior orbit inferiorly. She underwent a complete ophthalmic evaluation, magnetic resonance imaging, and histopathologic examination. RESULTS...

journal_title：Ocular immunology and inflammation

authors： Attia S,Zaouali S,Jeguirim H,Njim L,Kriaa S,Yahia SB,Khairallah M

更新日期：2006-12-01 00:00:00

abstract：:Purpose: To analyze the clinical features and long-term prognosis of uveitis in tubulointerstitial nephritis and uveitis (TINU) syndrome in a cohort of Chinese patients. Methods: A total of 32 patients with TINU syndrome between 2000 - 2016 were analyzed retrospectively. Results: Mild anterior inflammation was observe...

journal_title：Ocular immunology and inflammation

authors： Yang M,Chi Y,Guo C,Huang J,Yang L,Yang L

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:To show the current status of multimodal imaging and its role in supporting an early diagnosis of sympathetic ophthalmia. METHODS:The diagnosis is mainly clinical supported with ancillary investigations; mainly fluorescein angiography and others, including indocyanine angiography optical coherence tomography (...

journal_title：Ocular immunology and inflammation

authors： Mahajan S,Invernizzi A,Agrawal R,Biswas J,Rao NA,Gupta V

更新日期：2017-04-01 00:00:00

abstract：PURPOSE:To evaluate the effects of fluorescein fundus angiography (FFA) on semiautomated aqueous flare measurements. METHODS:Laser flare photometer (LFP) measurements was performed at baseline, 30 min, and 4 h after the intravenous administration of sodium fluorescein dye. FFA was performed immediately after the basel...

journal_title：Ocular immunology and inflammation

authors： Halim MS,Onghanseng N,Park JH,Yilmaz M,Segawa A,Ertop M,Hassan M,Tran AN,Aktas Z,Ozdek S,Gurelik G,Do DV,Sepah YJ,Nguyen QD,Hasanreisoglu M

更新日期：2020-09-23 00:00:00

abstract：:Tacrolimus (FK506) is effective in Japanese endogenous posterior uveitis (EPU), but there is limited data on its role in refractory EPU where cyclosporin A (CsA) toxicity/resistance develops. This open prospective clinical study aimed to assess the efficacy and adverse effects of low-dose FK506 therapy in western pati...

journal_title：Ocular immunology and inflammation

authors： Kilmartin DJ,Forrester JV,Dick AD

更新日期：1998-06-01 00:00:00

abstract：PURPOSE:To determine factors conferring an increased risk of developing ocular hypertension secondary to the fluocinolone acetonide (FA) sustained-release surgical implant (Retisert). DESIGN:Retrospective, observational case series. METHODS:Patients with a history of chronic noninfectious posterior uveitis undergoing...

journal_title：Ocular immunology and inflammation

authors： Sadowsky AJ,Pecen PE,Feinstein E,Palestine AG

更新日期：2020-07-03 00:00:00

abstract：PURPOSE:To describe demographic features and clinical and imaging characteristics of inflammatory choroidal neovascularization (CNV) in a Chinese population. METHODS:A retrospective case review of patients with CNV secondary to uveitis from 2002 to 2013. RESULTS:A total of 125 patients (150 eyes, 166 CNVs; bifocal CN...

journal_title：Ocular immunology and inflammation

authors： Wu K,Zhang X,Su Y,Ji Y,Zuo C,Li M,Wen F

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:To report outcomes and assess structural changes in the retina in patients with severe endophthalmitis. METHODS:Retrospective, nonrandomized, interventional case series at a tertiary referral centre. Spectral domain optical coherence tomography (OCT) images of both eyes were acquired at least 5 months after pa...

journal_title：Ocular immunology and inflammation

authors： Zinkernagel MS,Dysli C,Wolf S,Ebneter A

更新日期：2014-12-01 00:00:00

abstract：:Potent antiretroviral therapy can result in substantial improvement in the immune function of patients with AIDS. In some patients with preexisting cytomegalovirus (CMV) retinitis, a consequence of this improved immune function is increased intraocular inflammation. This phenomenon, termed 'immune recovery uveitis', i...

journal_title：Ocular immunology and inflammation

authors： Holland GN

更新日期：1999-12-01 00:00:00

abstract：PURPOSE:To describe scleral changes in chronic VKH. METHODS:Medical records of patients with chronic VKH were retrospectively reviewed. Change of scleral architecture was defined as progressive posterior bowing on OCT, axial length elongation, and/or increased myopia more than -1.0 D, not explicable by other etiologie...

journal_title：Ocular immunology and inflammation

authors： Harada Y,Bhat P,Munk MR,Goldstein DA

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:An HLA-DQ1 association has been suspected in patients who develop Propionibacterium acnes endophthalmitis following cataract surgery. New techniques exist which may help to define this association. MATERIALS AND METHODS:Patients with culture-proven P. acnes endophthalmitis following cataract surgery were HL...

journal_title：Ocular immunology and inflammation

authors： Davis JL,Winward KR,Lonardo EC,Nussenblatt RB,Meisler DM,Lee TD

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:To analyze the clinical features, course, management, and outcomes of tubercular (TB) uveitis in the pediatric population and assess the response to anti-tubercular therapy (ATT). METHODS:Hospital records of children (≤16 years) from a large tertiary-care institute between January 2001 and December 2015 were r...

journal_title：Ocular immunology and inflammation

authors： Kaur S,Aggarwal K,Agarwal A,Suri D,Gupta A,Singh R,Bansal R,Singh S,Singh N,Gupta A,Gupta V

更新日期：2018-01-01 00:00:00

abstract：AIM:To look at markers to differentiate ocular sarcoidosis from ocular tuberculosis in a high TB endemic population. MATERIALS & METHODS:Retrospective multicenter study involving seven tertiary eyecare centers in India between July 2016 to December 2016. Demographic, clinical and laboratory data were retrieved from re...

journal_title：Ocular immunology and inflammation

authors： Babu K,Biswas J,Agarwal M,Mahendradas P,Bansal R,Rathinam SR,Basu S,Ganesh SK,Konana VK,Vedhanayaki R,Philips M,Choudhary T

更新日期：2020-09-01 00:00:00

abstract：:Purpose: To evaluate the efficacy and safety of intravitreal ganciclovir (GCV) injection in refractory endotheliitis.Methods: Retrospectively recruited 25 eyes with endotheliitis, proved by clinical manifestations, positive PCR for viral DNA and responded poor to topical and systemic antiviral medications. All patient...

journal_title：Ocular immunology and inflammation

authors： Yu T,Peng RM,Xiao GG,Feng LN,Hong J

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:To describe the formation of a retinal pigment epithelial (RPE) tear following immunosuppressive treatment of a large choroidal granuloma in a patient with sarcoidosis-related panuveitis. METHODS:A 25-year-old woman presented with bilateral sarcoidosis-related panuveitis and optic disc edema in both eyes with ...

journal_title：Ocular immunology and inflammation

authors： Knickelbein JE,Wei M,Nussenblatt RB,Sen HN

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:To report the results of tocilizumab (TCZ) treatment in patients with Behçet uveitis (BU) who had failed conventional, interferon alpha, and anti-Tumor necrosis factor-alpha therapy. METHODS:We reviewed the records of five patients with BU treated with monthly infusions of TCZ 8 mg/kg. Outcome measures were vi...

journal_title：Ocular immunology and inflammation

authors： Eser Ozturk H,Oray M,Tugal-Tutkun I

更新日期：2018-01-01 00:00:00

abstract：:The eye is an immune-privileged site that uses specialized mechanisms to protect itself from damage and to preserve its visual acuity. Among the mechanisms that contribute to the eye's privileged existence is its ability to induce both local and peripheral tolerance to antigens that may transgress its chambers. Experi...

journal_title：Ocular immunology and inflammation

authors： Stein-Streilein J

更新日期：2005-04-01 00:00:00

abstract：PURPOSE:To define the indocyanine green (ICG) and fundus fluorescein angiographic (FFA) features of Behçet's disease. METHODS:The study included 49 eyes of 25 patients (19 males, 6 females; mean age: 34.1 years; age range: 14-68 years) with Behçet's disease and active ocular involvement that fulfilled the criteria of ...

journal_title：Ocular immunology and inflammation

authors： Gedik S,Akova Y,Yilmaz G,Bozbeyoğlu S

更新日期：2005-02-01 00:00:00

abstract：:In the pre-cyclosporin therapy era, BenEzra and Cohen(1) reported an appalling visual prognosis of patients with Behçet's disease, with 74% of eyes losing useful vision six to ten years after diagnosis. This experience was in a population largely of Mediterranean origin and it has been suggested that different ethnic ...

journal_title：Ocular immunology and inflammation

authors： Towler HM,Lightman S

更新日期：1993-01-01 00:00:00

abstract：PURPOSE:To determine the prevalence of ocular involvement in patients with acute disseminated tuberculosis and to assess the findings associated with ocular involvement. METHODS:Assessment of all intensive care (ICU) admissions with a differential diagnosis of mycobacterial sepsis during a period of one year, with a d...

journal_title：Ocular immunology and inflammation

authors： Mehta S

更新日期：2004-12-01 00:00:00

abstract：:Recent reports have shown that dry eye in Sjögren's syndrome (SS) is associated with reactivation of Epstein-Barr virus (EBV) in lacrimal glands. However, the number of patients examined were few and it has not been determined whether dry eye in the absence of SS is also related to EBV reactivation. The authors exam...

journal_title：Ocular immunology and inflammation

authors： Toda I,Ono M,Fujishima H,Tsubota K

更新日期：1994-01-01 00:00:00

abstract：:Aims: To evaluate associations between vision-related (VR-) and health-related (HR-) QoL metrics and inflammation and treatment in non-acute VKHD patients.Methods: Cross-sectional study in a tertiary center in Sao Paulo, Brazil with 22 patients with non-acute VKHD followed prospectively for ≥12 months since acute dise...

journal_title：Ocular immunology and inflammation

authors： Souto FMS,Missaka RFBG,Magalhães BM,Caetano VMC,Takiuti JT,Lavezzo MM,Sakata VM,Oyamada MK,Hirata CE,Yamamoto JH

更新日期：2019-10-31 00:00:00

abstract：PURPOSE:To compare Behçet uveitis patients who presented in the 1990s and 2000s. METHODS:Records of 170 patients seen in 1990-1994 and 258 patients seen in 2000-2004 were reviewed. Presenting features were analyzed in the whole cohort. Uveitis attacks, vision, complications, and immunomodulatory treatment (IMT) were c...

journal_title：Ocular immunology and inflammation

authors： Cingu AK,Onal S,Urgancioglu M,Tugal-Tutkun I

更新日期：2012-12-01 00:00:00

abstract：PURPOSE:To present the largest series reported so far of brimonidine induced granulomatous anterior uveitis. METHODS:Retrospective chart review of patients with chronic glaucoma on treatment with brimonidine presenting with anterior uveitis. RESULTS:19 eyes of 12 patients with chronic glaucoma developed anterior uvei...

journal_title：Ocular immunology and inflammation

authors： Beltz J,Zamir E

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To describe whole-body 18-fluorodeoxyglucose (FDG) positron emission tomography/computed radiographic tomography (PET-CT) imaging of ophthalmic patients with systemic sarcoidosis. METHODS:Four systemic sarcoidosis patients were evaluated with PET-CT for staging. Two had been treated for conjunctival melanoma a...

journal_title：Ocular immunology and inflammation

authors： Shulman JP,Latkany P,Chin KJ,Finger PT

更新日期：2009-03-01 00:00:00

abstract：PURPOSE:To determine the performance of T-SPOT.TB, an interferon gamma release assay test, in patients with ocular tuberculosis (TB) in a BCG-vaccinated, non-endemic population. METHODS:We employed a nested case-control design. In total, 45 subjects were enrolled (23 patients with ocular tuberculosis and 22 patients w...

journal_title：Ocular immunology and inflammation

authors： Urzua CA,Liberman P,Abuauad S,Sabat P,Castiglione E,Beltran-Videla MA,Aguilera R

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:To describe the clinical and histopathological features of post viper bite anterior segment ischemia. METHODS:Seven patients with ocular complications following viper bite referred to uveitis clinic had slit-lamp examination, intraocular pressure (IOP) measurement, and fundus evaluation. Iris and fundus fluore...

journal_title：Ocular immunology and inflammation

authors： Sivakumar RR,Rao NA

更新日期：2016-01-01 00:00:00