Brimonidine Induced Anterior Uveitis.

Abstract:

PURPOSE:To present the largest series reported so far of brimonidine induced granulomatous anterior uveitis. METHODS:Retrospective chart review of patients with chronic glaucoma on treatment with brimonidine presenting with anterior uveitis. RESULTS:19 eyes of 12 patients with chronic glaucoma developed anterior uveitis with granulomatous keratic precipitates after being treated with brimonidine for periods of 7 days to 5 years (mean 19.7 months, +18.6 months). One patient had a gap of 1 year between onset in one eye and onset in the other. Ten eyes (52.6%) had concurrent granulomatous conjunctivitis; 16 eyes were pseudophakic. Stopping brimonidine led to complete, rapid resolution of uveitis in all patients, in most cases (11 eyes, 58%) without topical corticosteroids. No recurrences have occurred after withdrawal of brimonidine, over a follow-up period of 12-52 months (mean 27.9 months, +13.8 months). CONCLUSIONS:Ophthalmologists should be aware of this easily reversible uveitis syndrome that is induced by a common glaucoma medication. Familiarity with this entity is essential in making the correct diagnosis and avoiding unnecessary investigations and interventions.

journal_name

Ocul Immunol Inflamm

authors

Beltz J,Zamir E

doi

10.3109/09273948.2015.1037845

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

128-33

issue

2

eissn

0927-3948

issn

1744-5078

journal_volume

24

pub_type

杂志文章
  • Atypical presentation of multiple evanescent white dot syndrome (MEWDS).

    abstract:PURPOSE:To present fundus autofluorescence (FAF), indocyanine green angiography (ICGA), and microperimetry (MP) findings of a patient with multiple evanescent white dot syndrome (MEWDS). METHODS:Observational case report. RESULTS:A 30-year-old woman with blurry vision was referred for evaluation. Fundus examination r...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940802026060

    authors: Yenerel NM,Kucumen B,Gorgun E,Dinc UA

    更新日期:2008-05-01 00:00:00

  • Idiopathic Central Nervous System Inflammatory Disease in the Setting of HLA-B27 Uveitis.

    abstract::Purpose: The purpose of the article is to describe a novel case of idiopathic central nervous system inflammatory disease with bilateral human leukocyte antigen (HLA)-B27-positive anterior uveitis. Methods/Results: A 15-year-old African American boy with bilateral HLA-B27-positive anterior uveitis controlled with topi...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2018.1449865

    authors: Crowell EL,Pfeiffer ML,Kamdar AA,Koenig MK,Wittenberg SE,Supsupin EP,Adesina OO

    更新日期:2019-01-01 00:00:00

  • Ocular Involvement in Muckle-Wells Syndrome.

    abstract::Purpose: To present the ocular findings of the members of a family that has the diagnosis of Muckle Wells syndrome, a form of cryopyrin associated periodic syndrome (CAPS).Materials and Methods: Nine patients with MWS were included in this study. Each study participant underwent a systemic evaluation, comprehensive op...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2018.1552305

    authors: Cekic S,Yalcinbayir O,Kilic SS

    更新日期:2020-01-01 00:00:00

  • Pleomorphism of stromal eosinophils in murine experimental onchocercal keratitis.

    abstract::Onchocercal keratitis (river blindness) is one of the leading worldwide causes of blindness. Light microscopic analysis of human specimens and corneal tissue from experimental models has implicated the eosinophil as an important cell in the inflammatory response. Our previous studies in experimental murine onchocercal...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273949709116890

    authors: Bardenstein DS,Lass JH,Kazura JW,Pearlman E

    更新日期:1997-09-01 00:00:00

  • Acute posterior multifocal placoid pigment epitheliopathy following mumps.

    abstract:PURPOSE:Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is an acquired inflammatory disorder affecting the retina, retinal pigment epithelium, and choroid of healthy adults. APMPPE has been reported to occur after diverse infectious diseases, suggesting a possible immune disorder. The primary site of...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1076/ocii.6.3.189.4038

    authors: Borruat FX,Piguet B,Herbort CP

    更新日期:1998-09-01 00:00:00

  • Unilateral Idiopathic Choroidal Effusion in a Patient Who Takes Sulfonamides.

    abstract:PURPOSE:To report a challenging case of unilateral choroidal effusion. METHODS:A case report about patient who presented with unilateral choroidal effusion and who was taking sulfonamides. Patient has been under care of a multidisciplinary team of uveitis consultant, ocular oncology consultant, and systemic oncology c...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2020.1770300

    authors: Lukic M,Westcott M

    更新日期:2020-07-09 00:00:00

  • Clinical Outcomes of Retinal Detachment Surgery following Cytomegalovirus Retinitis in Patients on Highly Active Anti-retroviral Therapy for Acquired Immune Deficiency Syndrome.

    abstract:AIM:The objective of this study is to describe the surgical outcomes of patients of HIV on HAART who underwent surgery for CMV retinitis related retinal detachment. METHOD AND MATERIALS:A retrospective analysis of the medical records of 40 eyes of 35 consecutive HIV positive patients who underwent surgical repair for ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,多中心研究

    doi:10.3109/09273948.2014.999376

    authors: Mathur G,Ratra D,Bhuibhar SS,Roy R

    更新日期:2015-01-01 00:00:00

  • Patterns of Uveitis among Patients Attending Jimma University Department of Ophthalmology, Jimma, Ethiopia.

    abstract::Introduction: Uveitis is an important cause of blindness and ocular morbidity in the world. The patterns of uveitis have not been well characterized in sub-Saharan Africa. Purpose: To describe the characteristics of uveitis among patients presenting to Jimma University Department of Ophthalmology (JUDO) from July 2013...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1644348

    authors: Tolesa K,Abateneh A,Kempen JH,Gelaw Y

    更新日期:2020-10-02 00:00:00

  • Interferon alpha 2b in the treatment of uveitic cystoid macular edema.

    abstract:PURPOSE:To determine the efficacy of interferon alpha 2b in the treatment of refractory, uveitic cystoid macular edema (CME). METHODS:Retrospective chart review of 4 patients attending the uveitis clinic at the Casey Eye Institute, Oregon Health & Science University. RESULTS:All 4 patients had uveitis and refractory ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2011.645989

    authors: Butler NJ,Suhler EB,Rosenbaum JT

    更新日期:2012-04-01 00:00:00

  • Does Pharmaceutical Compounding of Vascular Endothelial Growth Factor Inhibitors for Intravitreal Use Alter the Risk of Post-injection Endophthalmitis?

    abstract:PURPOSE:To investigate the safety of pharmaceutically compounded syringes for intravitreal administration of anti-vascular endothelial growth factor (anti-VEGF) drugs. METHODS:Single center, retrospective chart review. From 2015 to 2019, Oslo University Hospital, Norway gradually implemented pharmaceutical compounding...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2020.1820530

    authors: Blom K,Bragadóttir R,Sivertsen MS,Moe MC,Jørstad ØK

    更新日期:2020-10-07 00:00:00

  • Evaluation of the Anterior Segment Parameters of the Patients with Scleroderma.

    abstract:PURPOSE:To evaluate corneal parameters of scleroderma (SC) patients by Pentacam-HR. METHODS:Twenty-two eyes of 22 SC patients and 33 eyes of 33 control subjects were enrolled. All participants underwent Pentacam (Pentacam-HR, Oculus, Germany) evaluation. Both SC and control groups were divided into two subgroups as dr...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2015.1115079

    authors: Şahin M,Yüksel H,Şahin A,Cingü AK,Türkcü FM,Kaya S,Yazmalar L,Batmaz İ

    更新日期:2017-04-01 00:00:00

  • Evolving "Diagnostic" Criteria for Axial Spondyloarthritis in the Context of Anterior Uveitis.

    abstract::Anterior uveitis is far more common than intermediate, posterior or panuveitis. About 50% of patients with acute anterior uveitis are HLA B27+. Those who are HLA B27+ are highly likely to have associated back, joint, or tendon disease. The majority of patients with acute anterior uveitis and inflammatory low back pain...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:10.3109/09273948.2016.1158277

    authors: Rosenbaum JT

    更新日期:2016-08-01 00:00:00

  • Polymerase chain reaction for diagnosis of herpetic intraocular inflammation.

    abstract::The authors present a polymerase chain reaction method for rapid and direct diagnosis of herpetic intraocular infections using small volume samples of intraocular fluid from 29 patients with various intraocular inflammatory diseases and 24 controls with senile cataract. Of six patients with early acute retinal necrosi...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273949309086545

    authors: Usui M,Usui N,Goto H,Minoda H,Rai T

    更新日期:1993-01-01 00:00:00

  • Mucormycosis Endophthalmitis in a Silicone Oil-Filled Eye of an Immunocompetent Patient.

    abstract::Purpose:: Fungal endophthalmitis following pars plana vitrectomy with silicone oil tamponade is an infrequent entity. Filamentous fungi like aspergillus are generally associated with endophthalmitis. Mucor is a rarely implicated pathogen in cases of endophthalmitis with only two reported cases in medical literature. B...

    journal_title:Ocular immunology and inflammation

    pub_type: 信件

    doi:10.1080/09273948.2018.1518462

    authors: Dogra M,Bhutani G,Gupta V

    更新日期:2019-01-01 00:00:00

  • Causes of Hypertensive Anterior Uveitis in Thailand.

    abstract:PURPOSE:To determine the prevalence of viral infections in patients with hypertensive anterior uveitis in Thailand from polymerase chain reaction (PCR) of aqueous humor. METHODS:Thirty-one patients with anterior uveitis with intraocular pressure (IOP) above 25 mmHg were included for PCR analysis for cytomegalovirus (C...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1678651

    authors: Khieu C,Kongyai N,Pathanapitoon K,Van Der Eijk AA,Rothova A

    更新日期:2020-05-18 00:00:00

  • Clinical profile of ocular sarcoidosis in a South Indian patient population.

    abstract:AIM:To report the ocular and systemic features in patients with definite and presumed sarcoidosis presenting to a tertiary referral eye center in south India. MATERIALS AND METHODS:Retrospective observational case series. Records of 51 patients with diagnosis of sarcoidosis were retrieved. A complete ophthalmic evalua...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2010.495813

    authors: Babu K,Kini R,Mehta R,Abraham MP,Subbakrishna DK,Murthy KR

    更新日期:2010-10-01 00:00:00

  • The Emerging Challenge of Diagnosing Drug-resistant Tubercular Uveitis: Experience of 110 Eyes from North India.

    abstract::Background: Rapid and timely diagnosis of tubercular uveitis (TBU) is of paramount importance to save these eyes from blindness. The present study was, therefore, undertaken to carry out a comparative evaluation of Gene Xpert MTB/RIF (Xpert), MTBDRplus and Multiplex PCR (MPCR) for the diagnosis of TBU. These tests wer...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1655581

    authors: Sharma K,Gupta A,Sharma M,Sharma A,Bansal R,Sharma SP,Singh RD,Gupta V

    更新日期:2019-10-03 00:00:00

  • Combined low dose cyclosporine and prednisone down-regulate natural killer cell-like effector functions of CD8brightCD56+ T cells in patients with active Behçet uveitis.

    abstract:PURPOSE:To investigate the changes of effector-related phenotypic markers and the natural killer (NK)-like effector functions of CD8(bright)CD56+ T cells in patients with Behçet uveitis after combined cyclosporine and prednisone (Cs/Pd) treatment. METHODS:Ten patients with active Behçet panuveitis and 10 healthy contr...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940600966616

    authors: Ahn JK,Park YG,Park SW,Yoon KC,Yu HG,Chung H

    更新日期:2006-10-01 00:00:00

  • Evaluation of the Accuracy of T-SPOT.TB for the Diagnosis of Ocular Tuberculosis in a BCG-vaccinated, Non-endemic Population.

    abstract:PURPOSE:To determine the performance of T-SPOT.TB, an interferon gamma release assay test, in patients with ocular tuberculosis (TB) in a BCG-vaccinated, non-endemic population. METHODS:We employed a nested case-control design. In total, 45 subjects were enrolled (23 patients with ocular tuberculosis and 22 patients w...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2015.1135965

    authors: Urzua CA,Liberman P,Abuauad S,Sabat P,Castiglione E,Beltran-Videla MA,Aguilera R

    更新日期:2017-08-01 00:00:00

  • A comparison of heparin-coated and uncoated intraocular lenses in glaucoma patients undergoing combined cataract extraction and trabeculectomy and in diabetic patients undergoing cataract extraction.

    abstract::The postoperative course of cataract extraction and IOL implantation combined with trabeculectomy in glaucoma patients and of cataract extraction with intraocular lens (IOL) in diabetic patients is more complicated than that of cataract extraction with IOL implantation in otherwise healthy eyes. The main complications...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273949309057057

    authors: Zalish M,Rahmiel R,Pollack A,Milstein A,Oliver M

    更新日期:1993-01-01 00:00:00

  • Survival of corneal grafts after severe burns of the eye.

    abstract::The authors investigated 32 human corneal buttons of patients suffering from severe eye burns. The keratoplasties were performed in different periods after the burn and collected within five years. Grafts were followed-up until they failed because of ulceration or until rehabilitating keratoplasties were performed. Ea...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273949409057077

    authors: Becker J,Salla S,Redbrake C,Schrage NF,Reim M

    更新日期:1994-01-01 00:00:00

  • Collagen Cross-Linking in the Management of Microbial Keratitis.

    abstract::Increasing resistance to antimicrobial agents has contributed to an elevated risk of complications of infectious keratitis. Corneal collagen cross-linking (CXL) has been widely adopted for the management of keratoconus and post-refractive surgery corneal ectasia. It has recently been introduced as an option for treati...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:10.1080/09273948.2017.1414856

    authors: Bonzano C,Di Zazzo A,Barabino S,Coco G,Traverso CE

    更新日期:2019-01-01 00:00:00

  • Precise monitoring and differentiation of inflammatory events by indocyanine green (ICG) angiography in a case of recurrent posterior sarcoid uveitis.

    abstract:PURPOSE:By providing information on choroidal lesions, indocyanine green (ICG) angiography is complementary to fluorescein angiography in the workup of posterior uveitis. The aim here was to illustrate practically the suitability of performing dual fluorescein/ICG angiograms in a demonstrative case of recurrent presume...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1076/ocii.8.4.303.6458

    authors: Herbort CP

    更新日期:2000-12-01 00:00:00

  • Intravitreal Ranibizumab for the Treatment of Irvine-Gass Syndrome.

    abstract:PURPOSE:The purpose of our study was to evaluate the potential efficacy and safety of intravitreal ranibizumab in patients with pseudophakic cystoid macular edema (CME). METHODS:This retrospective study comprised 7 eyes with CME treated with intravitreal ranibizumab. Patients were examined at 1 week and 1 month after ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2014.898775

    authors: Mitropoulos PG,Chatziralli IP,Peponis VG,Drakos E,Parikakis EA

    更新日期:2015-06-01 00:00:00

  • Outcomes of "Early" Withdrawal of Corticosteroid Sparing Immunomodulatory Therapy for Birdshot Retinochoroidopathy.

    abstract::Purpose: To review early withdrawal of immunomodulatory therapy (IMT) for birdshot retinochoroidopathy (BSRC). Design: Retrospective case-series of sixteen patients with Human-leukocyte-antigen-A29-positive BSRC treated with IMT ≥ 1 year and discontinued prior to achieving durable remission, observed ≥ 6 months off IM...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2018.1506040

    authors: You C,Meese H,Stephenson A,Montieth A,Ma L,Hernandez M,Kubaisi B,Syeda S,Foster CS

    更新日期:2019-01-01 00:00:00

  • Tuberculin Skin Testing Induces Bilateral Tuberculous Uveitis in a Junior High School Student.

    abstract::We report a rare case of bilateral tuberculous uveitis associated with tuberculin skin testing (TST) in an otherwise healthy junior high school student. A 12-year-old boy presented with severely decreased vision in both eyes and a history of an intradermal PPD (purified protein derivative) skin test 12 days earlier. T...

    journal_title:Ocular immunology and inflammation

    pub_type: 信件

    doi:10.1080/09273948.2020.1778731

    authors: Zhao H,Peng X

    更新日期:2020-08-12 00:00:00

  • Association of Propionibacterium acnes endophthalmitis with HLA-DQw5.

    abstract:BACKGROUND:An HLA-DQ1 association has been suspected in patients who develop Propionibacterium acnes endophthalmitis following cataract surgery. New techniques exist which may help to define this association. MATERIALS AND METHODS:Patients with culture-proven P. acnes endophthalmitis following cataract surgery were HL...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273949609069124

    authors: Davis JL,Winward KR,Lonardo EC,Nussenblatt RB,Meisler DM,Lee TD

    更新日期:1996-01-01 00:00:00

  • Virus-Induced Anterior Uveitis (VIAU) in Immunocompromised Patients.

    abstract:PURPOSE:To describe the clinical characteristics, diagnosis, and treatment of VIAU in immunocompromised patients. METHODS:A critical review of literature was performed. RESULTS:Diagnosis and treatment of VIAU in immunocompromised patients may be a challenge due to atypical clinical-courses, severe presentations, and ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:10.1080/09273948.2018.1483519

    authors: de-la-Torre A

    更新日期:2018-01-01 00:00:00

  • Clinical Correlation between Acute Exudative Polymorphous Paraneoplastic Vitelliform Maculopathy and Metastatic Melanoma Disease Activity: A 48-month Longitudinal Case Report.

    abstract:PURPOSE:Longitudinal evaluation of acute exudative polymorphous paraneoplastic vitelliform maculopathy (AEPPVM) following diagnosis and treatment of metastatic melanoma. METHODS:Case report of a 47-year-old male with unknown primary metastatic melanoma and AEPPVM monitored before and during melanoma treatment using cl...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2020.1813782

    authors: Mueller CM,Hojjatie SL,Lawson DH,Jain N,Robinson J,Khan MK,Yushak ML,O'Keefe GAD

    更新日期:2020-10-06 00:00:00

  • A privileged view of NKT cells and peripheral tolerance through the eye.

    abstract::The eye is an immune-privileged site that uses specialized mechanisms to protect itself from damage and to preserve its visual acuity. Among the mechanisms that contribute to the eye's privileged existence is its ability to induce both local and peripheral tolerance to antigens that may transgress its chambers. Experi...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:10.1080/09273940490912371

    authors: Stein-Streilein J

    更新日期:2005-04-01 00:00:00