Collagen Cross-Linking in the Management of Microbial Keratitis.

Abstract:

:Increasing resistance to antimicrobial agents has contributed to an elevated risk of complications of infectious keratitis. Corneal collagen cross-linking (CXL) has been widely adopted for the management of keratoconus and post-refractive surgery corneal ectasia. It has recently been introduced as an option for treating keratitis due to multidrug resistant organisms. The purpose of this review is to discuss the rationale, safety, and evidence for CXL in infectious keratitis and its possible effect on ocular surface inflammation. Published data show that CXL is effective and safe as an adjunct to antibiotic treatment in selected cases of bacterial keratitis. The benefit of CXL probably varies according to the etiology of the infection.

journal_name

Ocul Immunol Inflamm

authors

Bonzano C,Di Zazzo A,Barabino S,Coco G,Traverso CE

doi

10.1080/09273948.2017.1414856

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

507-512

issue

3

eissn

0927-3948

issn

1744-5078

journal_volume

27

pub_type

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