Abstract:
PURPOSE:To evaluate the clinical course of patients with Behçet uveitis after discontinuation of infliximab (IFX) therapy. METHODS:Medical records of eight patients who discontinued treatment between 2010 and 2018 were retrospectively analyzed. The main outcome measures were frequency of uveitis attacks per year, best-corrected visual acuity (BCVA), aqueous flare, foveal thickness and fluorescein angiography (FA) scores before initiation, during treatment and after 6, 12, and 24 months of cessation of the IFX therapy. RESULTS:The mean follow-up after withdrawal of infusions was 38.6 ± 20.4 (12-90) months. Frequency of uveitis attacks, BCVA, aqueous flare, foveal thickness and FA scores were improved significantly after treatment (p < .05). In terms of these parameters, there was no significant difference between the periods of during treatment and after 6, 12, and 24 months of cessation of the IFX therapy. CONCLUSION:IFX therapy might be discontinued safely with an effective inflammation control in patients with Behçet uveitis.
journal_name
Ocul Immunol Inflammjournal_title
Ocular immunology and inflammationauthors
Köse HC,Yalçındağ Ndoi
10.1080/09273948.2020.1774907subject
Has Abstractpub_date
2020-08-11 00:00:00pages
1-5eissn
0927-3948issn
1744-5078pub_type
杂志文章abstract:PURPOSE:To describe the demographic and clinical profiles of uveitis patients seen at secondary and tertiary care centers in Turkey. METHODS:A nationwide web-based registry of patients with uveitis was initiated in November 2008. We analyzed data from a single baseline registry-enrollment visit. RESULTS:In 33 centers...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,多中心研究
doi:10.1080/09273948.2016.1196714
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:To report a case of post-streptococcal retinal vasculitis. DESIGN:Review of a case. METHODS:Review of patient chart and fluorescein angiography. RESULTS:A 17 year old African American female presented with moderate vitritis and macular edema in the right eye and retinal vessel sheathing in both eyes. CONCLU...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940701799163
更新日期:2008-01-01 00:00:00
abstract::Purpose: To assess changes in aqueous humor (AH) levels of cytokines following dexamethasone intravitreal implant (DEX) injection for diabetic macular edema (DME).Methods: Sixteen DME and cataract cases series study. Anterior chamber AH sampling was performed at baseline at DEX injection time (T1), cataract surgery 8 ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1636095
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To describe the results of Boston keratoprosthesis implantation in a patient with Stevens-Johnson syndrome following autologous submandibular gland transplantation. DESIGN:Observational case report. METHODS:We report the case of a man diagnosed with Stevens-Johnson syndrome. Autologous submandibular gland tra...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2016.1234624
更新日期:2018-01-01 00:00:00
abstract::Nedocromil sodium (NS) and sodium cromoglycate (CS) (both applied locally into the conjunctival sac) reduced in a dose dependent manner plasma extravasation induced by topical bradykinin and by topical substance P (SP), NS being approximately ten times more potent than CS. Plasma extravasation induced by SP was unaffe...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273949509057809
更新日期:1995-01-01 00:00:00
abstract::Purpose: To report a case of cystoid macular edema (CME) secondary to juvenile idiopathic arthritis (JIA)-associated uveitis. Case report: 26-year-old female patient presented with CME in both eyes. CME became refractory and TCZ-IV was initiated. After 12 infusions was stopped because grade 1 neuropenia developed. On ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1644350
更新日期:2019-10-07 00:00:00
abstract::Purpose: To report a case of chronic anterior uveitis associated with relapsing polychondritis (RP).Case Report: A 43-year-old female patient presenting with bilateral progressive vision loss was diagnosed with bilateral anterior uveitis. According to her clinical signs and symptoms and biopsy results, RP was ultimate...
journal_title:Ocular immunology and inflammation
pub_type: 信件
doi:10.1080/09273948.2018.1547834
更新日期:2020-01-01 00:00:00
abstract::Aim: Ocular sarcoidosis presents a diagnostic challenge because of its varied clinical presentations. It is important to distinguish sarcoidosis from other uveitis diseases. Multimodal imaging provides useful data to be introduced into clinical practice. Methods: This is a review article. Conclusions: This review arti...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2020.1751210
更新日期:2020-11-16 00:00:00
abstract:PURPOSE:To evaluate the clinical outcome and safety of adalimumab in patients with Vogt-Koyanagi-Harada (VKH) disease. METHODS:VKH patients treated with adalimumab seen at the University of Buenos Aires were reviewed. Main outcome measures were visual acuity, anterior segment inflammation, optic nerve inflammation (ON...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2016.1236969
更新日期:2018-01-01 00:00:00
abstract::Purpose: To describe tuberculous uveitis (TU) presenting as a bullous retinal detachment (RD) and to perform a comprehensive literature review on TU with similar features. Methods: Observational case report and systematic literature review. Results: An 84-year-old woman presented with bilateral granulomatous uveitis a...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1485958
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:The purpose of this study was to examine 2 cases of cytomegalovirus (CMV) retinitis, occuring in 2 immunocompentent adult patients. METHODS:Case selection and literature review. RESULTS:Both patients cited significantly decreased vision despite systemic, topical, and/or local corticosteroid use. Neither patie...
journal_title:Ocular immunology and inflammation
pub_type: 信件,评审
doi:10.3109/09273948.2013.786095
更新日期:2013-08-01 00:00:00
abstract:PURPOSE:To describe a case of orbital sarcoidosis manifesting with enophthalmos. METHODS:A 60-year-old woman presented with right enophthalmos. She had a palpable mass in her anterior orbit inferiorly. She underwent a complete ophthalmic evaluation, magnetic resonance imaging, and histopathologic examination. RESULTS...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940601038589
更新日期:2006-12-01 00:00:00
abstract:PURPOSE:To investigate prognostic factors for retinal sensitivity assessed by microperimetry in patients with Vogt-Koyanagi-Harada (VKH) disease. METHODS:In total, 34 patients with initial-onset acute disease and 19 patients with chronic recurrent disease were retrospectively evaluated. RESULTS:The mean follow-up per...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2016.1139730
更新日期:2017-08-01 00:00:00
abstract:PURPOSE:To evaluate corneal parameters of scleroderma (SC) patients by Pentacam-HR. METHODS:Twenty-two eyes of 22 SC patients and 33 eyes of 33 control subjects were enrolled. All participants underwent Pentacam (Pentacam-HR, Oculus, Germany) evaluation. Both SC and control groups were divided into two subgroups as dr...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2015.1115079
更新日期:2017-04-01 00:00:00
abstract::Purpose: To evaluate retinal and choroidal microvascular features of VKH patients in acute and convalescent phases after treatment using OCTA.Methods: A prospective, observational study was conducted in patients with initial VKH at the acute stage (n = 15) and healthy participants (n = 15) served as controls. After 3-...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1695856
更新日期:2020-01-03 00:00:00
abstract:PURPOSE:To assess the retinal nerve fiber layer thickness in children with human immunodeficiency virus disease without cytomegalovirus retinitis or visual symptoms. METHODS:Thirty-eight eyes of 19 human immunodeficiency virus-positive children (group A) with visual acuity of 20/20 or better, normal color vision testi...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940701375154
更新日期:2007-07-01 00:00:00
abstract:PURPOSE:Uveitis is the most common extra-articular manifestation of juvenile idiopathic arthritis (JIA) and is associated with considerable morbidity. The aim of this study was to examine the risk factors associated with uveitis in oligoarticular JIA. METHODS:We conducted a chart review of 86 patients with oligoarticu...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2013.841495
更新日期:2014-06-01 00:00:00
abstract::Uveitis is an intraocular inflammation that can be caused by infection, autoimmune disease, trauma or malignancy. It is a serious cause of visual handicap and therapy is targeted at: removal of possible infectious agents, the immunological processes that lead to or sustain the inflammation and finally to prevent or tr...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273949609079654
更新日期:1996-01-01 00:00:00
abstract:PURPOSE:To evaluate the effects of fluorescein fundus angiography (FFA) on semiautomated aqueous flare measurements. METHODS:Laser flare photometer (LFP) measurements was performed at baseline, 30 min, and 4 h after the intravenous administration of sodium fluorescein dye. FFA was performed immediately after the basel...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2020.1799036
更新日期:2020-09-23 00:00:00
abstract::We report on a 22-years-old Thai male patient with congenital HIV infection. Due to his non-adherence to antiretroviral treatment he developed disseminated Talaromyces marneffei infection and was treated with intravenous amphotericin B. Despite this treatment, he presented with bilateral granulomatous anterior uveitis...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1657468
更新日期:2020-10-02 00:00:00
abstract::Several subjective and arbitrary grading methods are used in assessing cell and flare in uveitis. Clinicians are in need of an objective method of determining and monitoring active inflammation. We studied the correlation of changes in macular thickness between the visits and compared the change to visual acuity (VA),...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940802702587
更新日期:2009-07-01 00:00:00
abstract::Purpose: To investigate whether variants in the ARMC9 gene encoding KU-MEL-1 are associated with Vogt-Koyanagi-Harada (VKH) disease in a Japanese population. Methods: We recruited 380 Japanese patients with VKH disease and 744 Japanese healthy controls to genotype seven single-nucleotide polymorphisms (SNPs) in ARMC9....
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1523438
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To present the largest series reported so far of brimonidine induced granulomatous anterior uveitis. METHODS:Retrospective chart review of patients with chronic glaucoma on treatment with brimonidine presenting with anterior uveitis. RESULTS:19 eyes of 12 patients with chronic glaucoma developed anterior uvei...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2015.1037845
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:To describe retinal vascular changes in Birdshot Retinochoroiditis (BSRC) with multimodal imaging techniques and functional values. METHODS:In this single-center study, 64 eyes of 32 subjects with BSRC were classified according to disease activity and duration and underwent imaging with spectral domain optical...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2017.1375532
更新日期:2017-10-01 00:00:00
abstract::Purpose: To describe with multimodal imaging a case of post-infectious unilateral outer retinopathy with choroiditis. Methods: Retrospective chart review of a case of a 67-year old male who presented following the onset of viral symptoms with an acute onset outer retinopathy, small vessel leakage on fluorescein angiog...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1485954
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To report the clinical course, treatment response, and prognosis of Stenotrophomonas maltophilia endophthalmitis following cataract extraction. METHODS:The clinical records of six cases of S. maltophilia endophthalmitis after cataract extraction were retrospectively reviewed. Data were collected for surgical c...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940590950981
更新日期:2006-02-01 00:00:00
abstract::Anterior uveitis is far more common than intermediate, posterior or panuveitis. About 50% of patients with acute anterior uveitis are HLA B27+. Those who are HLA B27+ are highly likely to have associated back, joint, or tendon disease. The majority of patients with acute anterior uveitis and inflammatory low back pain...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:10.3109/09273948.2016.1158277
更新日期:2016-08-01 00:00:00
abstract:AIM:To report the ocular and systemic features in patients with definite and presumed sarcoidosis presenting to a tertiary referral eye center in south India. MATERIALS AND METHODS:Retrospective observational case series. Records of 51 patients with diagnosis of sarcoidosis were retrieved. A complete ophthalmic evalua...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2010.495813
更新日期:2010-10-01 00:00:00
abstract:PURPOSE:To evaluate multifocal evanescent white dot syndrome (MEWDS) patients with and without overlapping multifocal choroiditis (MFC). METHODS:Thirty-four patients diagnosed between November 2008 and August 2018 at 2 hospitals were retrospectively reviewed. Multimodal imaging including optical coherence tomography a...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2020.1795206
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:ICON is a fusion protein composed of factor VII, the natural ligand for tissue factor, conjugated to the Fc domain of a human IgG1 immunoglobulin. It binds to the tissue factor expressed on neovascular endothelia and initiates a cytolytic immune attack that destroys the neovascular tissue. We previously showed ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940601147760
更新日期:2007-01-01 00:00:00