Recent developments in the treatment of posterior uveitis.

Abstract:

:Uveitis is an intraocular inflammation that can be caused by infection, autoimmune disease, trauma or malignancy. It is a serious cause of visual handicap and therapy is targeted at: removal of possible infectious agents, the immunological processes that lead to or sustain the inflammation and finally to prevent or treat the destructive effects of the inflammation on the delicate ocular structures. In this review the latest developments concerning the treatment of posterior uveitis are illuminated, e. g., new approaches concerning the treatment of infectious uveitis including the therapy of herpes virus (VZV, HSV and CMV), bacterial and toxoplasma infections of the eye. Several new ways to influence the immune response and inflammation are described including the use of interferons, modulation of cytokines, soft steroids, other new immunosuppressive drugs and treatment of autoimmune uveitis by oral tolerization. An overview is given to illustrate new ways to administer drugs into eyes, such as intravitreal devices. Finally new developments in the field of the treatment of the various complications of uveitis (cystoid macular edema) are described.

journal_name

Ocul Immunol Inflamm

authors

Suttorp-Schulten MS,Jager MJ,Kijlstra A

doi

10.3109/09273949609079654

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

207-17

issue

4

eissn

0927-3948

issn

1744-5078

journal_volume

4

pub_type

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