Neuro-Behcet Disease and Ocular Inflammation: A Case Report and Literature Review.

Abstract:

:Purpose: To describe a case of panuveitis with occlusive vasculitis leading to the diagnosis of neuro-Behcet disease (NBD) and discuss the relationship between uveitis and NBD. Methods: Case report with a literature review of ocular inflammation in NBD. Results: A 26-year-old woman with a seven-month history of recurrent cerebral venous sinus thromboses (CVST) and right-sided hemiparalysis secondary to rhombencephalitis presented with bilateral panuveitis and occlusive retinal vasculitis. Systemic evaluations were negative for hypercoagulability and infection. Although HLA-51 negative, the diagnosis was consistent with NBD. Conclusion: NBD is a rare subset of BD with a limited number of studies and patients. However, uveitis is more common in adults with parenchymal disease; may predate the development of neurological symptoms. The most common locations of ocular inflammation were posterior and panuveitis. MRI/V of the brain can identify enhancing lesions in the rhombencephalon or CVST in patients with uveitis with neurological findings.

journal_name

Ocul Immunol Inflamm

authors

Patel SA,Okeagu C,Jones K,Chaudhry A,Berkenstock MK

doi

10.1080/09273948.2020.1787461

subject

Has Abstract

pub_date

2020-08-19 00:00:00

pages

1-9

eissn

0927-3948

issn

1744-5078

pub_type

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