Comparison of presenting features and three-year disease course in Turkish patients with Behçet uveitis who presented in the early 1990s and the early 2000s.

Abstract:

PURPOSE:To compare Behçet uveitis patients who presented in the 1990s and 2000s. METHODS:Records of 170 patients seen in 1990-1994 and 258 patients seen in 2000-2004 were reviewed. Presenting features were analyzed in the whole cohort. Uveitis attacks, vision, complications, and immunomodulatory treatment (IMT) were compared in patients with 3-year follow-up. RESULTS:Posterior segment involvement was less common, visual acuity was better, and more patients received IMT before referral in the 2000s. Follow-up revealed no significant difference in number of uveitis attacks in the first 3 years. Less eyes lost useful vision, no patient became legally blind, and fewer severe ocular complications occurred in the 2000s. IMT was started within 3 months in more patients and interferon alfa-2a was used only in the latter study period. CONCLUSIONS:The findings suggest a milder disease at referral, lower rate of severe complications, and a better 3-year visual outcome in patients who presented in the early 2000s.

journal_name

Ocul Immunol Inflamm

authors

Cingu AK,Onal S,Urgancioglu M,Tugal-Tutkun I

doi

10.3109/09273948.2012.713159

subject

Has Abstract

pub_date

2012-12-01 00:00:00

pages

423-8

issue

6

eissn

0927-3948

issn

1744-5078

journal_volume

20

pub_type

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