Abstract:
PURPOSE:To describe an unusual manifestation of sarcoidosis as a large tumor of the iris and ciliary body without any other involvement of the body. METHODS:We describe a 20-year-old female presenting with a granulomatous tumor of the right iris and ciliary body and concomitant uveitis. RESULTS:Extensive ocular and systemic workup revealed the tumor to be a large solitary sarcoid granuloma. As systemic steroids were not able to control the activity of the uveitis and granuloma, only the initiation of immunosuppressive therapy with cyclosporine A achieved a lasting remission. CONCLUSION:The possibility of an exclusively ocular sarcoidosis should always be kept in mind despite negative regular screening tests. In these cases, a biopsy should be considered and immunosuppressive agents like cyclosporine A should be evaluated in cases not responding to first-line treatment with systemic steroids.
journal_name
Ocul Immunol Inflammjournal_title
Ocular immunology and inflammationauthors
Maca SM,Firbas U,Hauff W,Zettinig G,Horvat R,Barisani-Asenbauer Tdoi
10.1080/092739490500156subject
Has Abstractpub_date
2004-09-01 00:00:00pages
237-40issue
3eissn
0927-3948issn
1744-5078pii
F3D4PDY6HV2CTLDHjournal_volume
12pub_type
杂志文章abstract::Purpose: To identify the risk factors for the development of subretinal fibrosis (SRF) among patients with Vogt-Koyanagi-Harada (VKH) syndrome. Methods: In this case-control study, electronic clinical records from patients diagnosed with VKH syndrome who attended the Inflammatory Eye Disease Clinic at a tertiary care ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2020.1825750
更新日期:2020-10-06 00:00:00
abstract:OBJECTIVE:To describe the medical treatment of severe ocular hypotony in HIV-seropositive patients with cytomegalovirus retinitis and cidofovir-associated uveitis. PATIENTS AND METHODS:Two HIV-seropositive patients with cytomegalovirus retinitis and cidofovir-associated uveitis complicated by severe ocular hypotony we...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1076/ocii.9.3.211.3968
更新日期:2001-09-01 00:00:00
abstract::Experimental autoimmune uveoretinitis (EAU) induced by immunization of male Lewis rats with bovine S-antigen (S-Ag) is prevented by injection of S-Ag into the testis prior to immunization. This protection of animals is due to the induction of systemic immunotolerance or immunosuppression, which the authors designate o...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273949509085041
更新日期:1995-01-01 00:00:00
abstract::Purpose: To assess changes in aqueous humor (AH) levels of cytokines following dexamethasone intravitreal implant (DEX) injection for diabetic macular edema (DME).Methods: Sixteen DME and cataract cases series study. Anterior chamber AH sampling was performed at baseline at DEX injection time (T1), cataract surgery 8 ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1636095
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:ICON is a fusion protein composed of factor VII, the natural ligand for tissue factor, conjugated to the Fc domain of a human IgG1 immunoglobulin. It binds to the tissue factor expressed on neovascular endothelia and initiates a cytolytic immune attack that destroys the neovascular tissue. We previously showed ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940601147760
更新日期:2007-01-01 00:00:00
abstract::Purpose: To investigate the prevalence and characteristics of ocular manifestations of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) in patients treated at a tertiary referral center in Taiwan during a time of highly active antiretroviral therapy (HAART) Materials and Methods: A retrospect...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1499939
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To compare the contamination rate between 27-gauge and 30-guage needles used for intravitreal injection (IVT). METHODS:Patients undergoing IVT injections were enrolled prospectively. Injections were performed with 27- or 30-gauge needles. All needle tips were collected and placed in brain-heart infusion broth....
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2013.801988
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:To evaluate the safety and efficacy of intravitreal triamcinolone acetonide (TA) for treating macular edema secondary to non-infectious uveitis. METHODS:Retrospective review of sixteen patients (20 eyes) with chronic cystoid macular edema (CME) as a consequence of controlled intermediate uveitis, posterior ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940590933511
更新日期:2005-04-01 00:00:00
abstract:PURPOSE:To describe a case of orbital sarcoidosis manifesting with enophthalmos. METHODS:A 60-year-old woman presented with right enophthalmos. She had a palpable mass in her anterior orbit inferiorly. She underwent a complete ophthalmic evaluation, magnetic resonance imaging, and histopathologic examination. RESULTS...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940601038589
更新日期:2006-12-01 00:00:00
abstract:PURPOSE:Primary vitreoretinal lymphomas (PVRL) pose a major diagnostic challenge, especially in the countries with a high prevalence of infectious variety of uveitis. The present study aims to report the clinical characteristics and diagnostic difficulties in patients with PVRL in an Indian Population. METHODS:Retrosp...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2016.1139731
更新日期:2017-10-01 00:00:00
abstract::Purpose: To emphasize the different manifestations of ocular involvement in Whipple disease with challenge in establishing the diagnosis as clinical, laboratory, and histological features could mimic other uveitis entities. Methods: Case reports of three patients. Results: The first patient was an African male sufferi...
journal_title:Ocular immunology and inflammation
pub_type: 信件
doi:10.1080/09273948.2018.1518461
更新日期:2019-01-01 00:00:00
abstract::Purpose: To describe the long-term clinical outcomes in a cohort of uveitic eyes treated with the intravitreal dexamethasone implant (Ozurdex; Allergan, Inc).Methods: Seventy-nine (63 patients) receiving 134 implant injections over 82 months were included. Indication, visual acuity (VA), intraocular pressure (IOP), vi...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1578380
更新日期:2020-01-01 00:00:00
abstract::Purpose: To analyse the association between skin score with corneal biomechanics and dry eye tests in systemic sclerosis (SSc). Methods: 112 cases (limited SSc (lcSSc), n=50; diffuse SSc (dcSSc), n=32; controls, n=30) were included in the study. Corneal hysteresis (CH), corneal resistance factor (CRF), Schirmer 1, 2 ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1501496
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Equine uveitis is a spontaneous disorder of horses that can serve as a model for the study of human uveitis. Although the initial presentation is that of an anterior uveitis, retinal involvement has been noted in some cases. We report here the immunohistopathology of retinas from horses with uveitis. METHOD...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1076/ocii.6.4.239.4026
更新日期:1998-12-01 00:00:00
abstract::Aims: To evaluate associations between vision-related (VR-) and health-related (HR-) QoL metrics and inflammation and treatment in non-acute VKHD patients.Methods: Cross-sectional study in a tertiary center in Sao Paulo, Brazil with 22 patients with non-acute VKHD followed prospectively for ≥12 months since acute dise...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1668431
更新日期:2019-10-31 00:00:00
abstract::We report a rare case of bilateral tuberculous uveitis associated with tuberculin skin testing (TST) in an otherwise healthy junior high school student. A 12-year-old boy presented with severely decreased vision in both eyes and a history of an intradermal PPD (purified protein derivative) skin test 12 days earlier. T...
journal_title:Ocular immunology and inflammation
pub_type: 信件
doi:10.1080/09273948.2020.1778731
更新日期:2020-08-12 00:00:00
abstract:PURPOSE:To report a case of acute retinal necrosis (ARN) occurring in the opposite eye to the ophthalmic shingles eruption. DESIGN:Case report. METHODS:Clinical examination and multimodal imaging review, including ultra-widefield photography and fluorescein angiography (FA). RESULTS:A 49-years-old man attended the U...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2020.1770298
更新日期:2020-07-09 00:00:00
abstract:PURPOSE:To assess long-term efficacy and safety of infliximab for refractory Behçet disease (BD) uveitis and to evaluate the effect of withdrawal of infliximab after achieving long-term remission. METHODS:Retrospective study of 19 patients. RESULTS:Mean follow-up was 44.1 ± 36.5 months and mean number of infliximab i...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2013.779727
更新日期:2013-12-01 00:00:00
abstract:PURPOSE:To evaluate the 10-year drug retention rate of infliximab (IFX) in Behçet's disease (BD)-related uveitis, the effect of a concomitant use of disease modifying anti-rheumatic drugs (DMARDs) on drug survival and differences according to the lines of biologic treatment. METHODS:Cumulative survival rates were stud...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2017.1391297
更新日期:2019-01-01 00:00:00
abstract::Purpose: To describe a case of panuveitis with occlusive vasculitis leading to the diagnosis of neuro-Behcet disease (NBD) and discuss the relationship between uveitis and NBD. Methods: Case report with a literature review of ocular inflammation in NBD. Results: A 26-year-old woman with a seven-month history of recurr...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2020.1787461
更新日期:2020-08-19 00:00:00
abstract:PURPOSE:To report the results of tocilizumab (TCZ) treatment in patients with Behçet uveitis (BU) who had failed conventional, interferon alpha, and anti-Tumor necrosis factor-alpha therapy. METHODS:We reviewed the records of five patients with BU treated with monthly infusions of TCZ 8 mg/kg. Outcome measures were vi...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2017.1355471
更新日期:2018-01-01 00:00:00
abstract::Behçet's disease is one of the most difficult forms of uveitis to treat. Variety in disease presentation and severity, as well as regional differences in standard of care, demand a tailor-made approach. Anterior segment inflammation generally responds to topical corticosteroids. However, the onset of posterior segment...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:
更新日期:2000-06-01 00:00:00
abstract:PURPOSE:To determine the performance of T-SPOT.TB, an interferon gamma release assay test, in patients with ocular tuberculosis (TB) in a BCG-vaccinated, non-endemic population. METHODS:We employed a nested case-control design. In total, 45 subjects were enrolled (23 patients with ocular tuberculosis and 22 patients w...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2015.1135965
更新日期:2017-08-01 00:00:00
abstract:PURPOSE:To report mycobacterial load in the vitreous of patients labeled as having Eales' disease. METHODS:Eighty-eight patients were prospectively enrolled into 3 groups: 28 patients with so-called Eales' disease (group A); 30 positive controls with specific uveitis syndromes (group B), and 30 negative controls (grou...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2012.658134
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:To describe whole-body 18-fluorodeoxyglucose (FDG) positron emission tomography/computed radiographic tomography (PET-CT) imaging of ophthalmic patients with systemic sarcoidosis. METHODS:Four systemic sarcoidosis patients were evaluated with PET-CT for staging. Two had been treated for conjunctival melanoma a...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940802596567
更新日期:2009-03-01 00:00:00
abstract:PURPOSE:To evaluate morphology of the optic nerve head and visual field in AIDS patients without retinitis. METHODS:One randomly selected eye from 246 patients with AIDS without retinitis was evaluated from prospective multicenter Longitudinal Studies of Ocular Complications of AIDS. Stereo fundus photographs of OHN a...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.3109/09273948.2012.694552
更新日期:2012-10-01 00:00:00
abstract::Purpose: To compare vessel density (VD) as measured by optical coherence tomography angiography (OCTA), in uveitic eyes with secondary glaucoma (UG) with VD in uveitic eyes without glaucoma (UV), eyes with primary open-angle glaucoma (POAG), and healthy eyes (HY). Methods: VD was measured at the following segmentation...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2020.1745246
更新日期:2020-11-13 00:00:00
abstract::Purpose:: Fungal endophthalmitis following pars plana vitrectomy with silicone oil tamponade is an infrequent entity. Filamentous fungi like aspergillus are generally associated with endophthalmitis. Mucor is a rarely implicated pathogen in cases of endophthalmitis with only two reported cases in medical literature. B...
journal_title:Ocular immunology and inflammation
pub_type: 信件
doi:10.1080/09273948.2018.1518462
更新日期:2019-01-01 00:00:00
abstract::Onchocercal keratitis (river blindness) is one of the leading worldwide causes of blindness. Light microscopic analysis of human specimens and corneal tissue from experimental models has implicated the eosinophil as an important cell in the inflammatory response. Our previous studies in experimental murine onchocercal...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273949709116890
更新日期:1997-09-01 00:00:00
abstract::Purpose: To describe the distinguishing features of retinitis-like lesions seen in vitreoretinal lymphoma (VRL) from viral and toxoplasma retinitis. Methods: In this multicenter, retrospective study, we reviewed charts and imaging of consecutive patients with VRL. The associated features and the characteristics of ret...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1648835
更新日期:2019-09-30 00:00:00