Abstract:
:Purpose: To identify the risk factors for the development of subretinal fibrosis (SRF) among patients with Vogt-Koyanagi-Harada (VKH) syndrome. Methods: In this case-control study, electronic clinical records from patients diagnosed with VKH syndrome who attended the Inflammatory Eye Disease Clinic at a tertiary care ophthalmology reference center were assessed to identify risk factors from demographic, clinical, and epidemiological variables. Cases were defined as SRF and VKH, whereas the controls were VKH patients without SRF. Results: A total of 150 electronic charts were reviewed, 92 patients with a follow-up longer than 12 months were included; 39 cases and 53 controls. A multivariate analysis found bullous serous retinal detachment as a significant risk factor for SRF (adjusted OR 8.93, 95% CI 1.94-41.1). Conclusion: Patients with VKH syndrome who develop a bullous retinal detachment have an 8 times higher risk of developing SRF in the long term.
journal_name
Ocul Immunol Inflammjournal_title
Ocular immunology and inflammationauthors
Golzarri MF,Cheja-Kalb R,Concha-Del-Río LE,Gonzalez-Salinas R,Arellanes-García Ldoi
10.1080/09273948.2020.1825750subject
Has Abstractpub_date
2020-10-06 00:00:00pages
1-5eissn
0927-3948issn
1744-5078pub_type
杂志文章abstract:PURPOSE:To describe demographic features and clinical and imaging characteristics of inflammatory choroidal neovascularization (CNV) in a Chinese population. METHODS:A retrospective case review of patients with CNV secondary to uveitis from 2002 to 2013. RESULTS:A total of 125 patients (150 eyes, 166 CNVs; bifocal CN...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2015.1015741
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:The purpose of this study was to examine 2 cases of cytomegalovirus (CMV) retinitis, occuring in 2 immunocompentent adult patients. METHODS:Case selection and literature review. RESULTS:Both patients cited significantly decreased vision despite systemic, topical, and/or local corticosteroid use. Neither patie...
journal_title:Ocular immunology and inflammation
pub_type: 信件,评审
doi:10.3109/09273948.2013.786095
更新日期:2013-08-01 00:00:00
abstract::Purpose: To investigate the prevalence of macular abnormalities in Chinese Vogt-Koyanagi-Harada (VKH) patients.Methods: Clinical characteristics, therapeutic effectiveness and visual outcome were reviewed and analyzed.Results: The most common macular abnormality was macular edema (ME), followed by macular choroidal ne...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1624781
更新日期:2019-01-01 00:00:00
abstract::Increasing resistance to antimicrobial agents has contributed to an elevated risk of complications of infectious keratitis. Corneal collagen cross-linking (CXL) has been widely adopted for the management of keratoconus and post-refractive surgery corneal ectasia. It has recently been introduced as an option for treati...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:10.1080/09273948.2017.1414856
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To evaluate the effects of fluorescein fundus angiography (FFA) on semiautomated aqueous flare measurements. METHODS:Laser flare photometer (LFP) measurements was performed at baseline, 30 min, and 4 h after the intravenous administration of sodium fluorescein dye. FFA was performed immediately after the basel...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2020.1799036
更新日期:2020-09-23 00:00:00
abstract::Purpose: To investigate whether variants in the ARMC9 gene encoding KU-MEL-1 are associated with Vogt-Koyanagi-Harada (VKH) disease in a Japanese population. Methods: We recruited 380 Japanese patients with VKH disease and 744 Japanese healthy controls to genotype seven single-nucleotide polymorphisms (SNPs) in ARMC9....
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1523438
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To report the results of tocilizumab (TCZ) treatment in patients with Behçet uveitis (BU) who had failed conventional, interferon alpha, and anti-Tumor necrosis factor-alpha therapy. METHODS:We reviewed the records of five patients with BU treated with monthly infusions of TCZ 8 mg/kg. Outcome measures were vi...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2017.1355471
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:Copper (Cu) is an essential trace element; however excess is toxic due to the pro-oxidant activity. Increased intracellular Cu levels in vitreous and monocyte were reported in Eales disease (ED) previously. Copper transporter1 (CTR1) maintains copper homeostasis and hence, we studied the presence of CTR1 in ocu...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2015.1071404
更新日期:2016-12-01 00:00:00
abstract:PURPOSE:To report a case of post-streptococcal retinal vasculitis. DESIGN:Review of a case. METHODS:Review of patient chart and fluorescein angiography. RESULTS:A 17 year old African American female presented with moderate vitritis and macular edema in the right eye and retinal vessel sheathing in both eyes. CONCLU...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940701799163
更新日期:2008-01-01 00:00:00
abstract::Intraocular tuberculosis presents a diagnostic challenge because of its protean clinical manifestations. Thus, it becomes imperative to distinguish chorioretinal inflammation due to tuberculosis from other infectious as well as non-infectious posterior uveitis since the clinical manifestations of these entities may be...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:10.1080/09273948.2016.1231332
更新日期:2017-02-01 00:00:00
abstract::The eye is an immune-privileged site that uses specialized mechanisms to protect itself from damage and to preserve its visual acuity. Among the mechanisms that contribute to the eye's privileged existence is its ability to induce both local and peripheral tolerance to antigens that may transgress its chambers. Experi...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:10.1080/09273940490912371
更新日期:2005-04-01 00:00:00
abstract::Acute anterior uveitis (AAU) is the commonest type of uveitis and HLA-B27 AAU is the most frequently recognized type of acute anterior uveitis and anterior uveitis overall. Recent evidence indicates that acute anterior uveitis is a heterogenous disease, is polygenic and is frequently associated with the spondyloarthro...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:10.3109/09273948.2016.1158283
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:To report a case of subretinal fibrosis and uveitis syndrome in association with ectodermal dysplasia. METHODS:Chart review of a patient with subretinal fibrosis and uveitis syndrome and ectodermal dysplasia. RESULTS:The authors identified one case of a patient with the diagnoses of subretinal fibrosis and uv...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273940903168670
更新日期:2009-09-01 00:00:00
abstract:PURPOSE:To assess the retinal nerve fiber layer thickness in children with human immunodeficiency virus disease without cytomegalovirus retinitis or visual symptoms. METHODS:Thirty-eight eyes of 19 human immunodeficiency virus-positive children (group A) with visual acuity of 20/20 or better, normal color vision testi...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940701375154
更新日期:2007-07-01 00:00:00
abstract::Purpose: The purpose of the study is to quantify aqueous flare using laser flare photometry (LFM) in patients undergoing 25-G pars plana vitrectomy (PPV) and assess the need for postoperative topical corticosteroid administration . Methods: Prospective evaluation of 50 eyes (50 patients) was performed using LFM until ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1449867
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To compare levels of selected mediators in serums and aqueous humor (AH) of type 2 diabetes mellitus cataract patients with senile cataract patients, and to determine their association with postoperative corneal edema (CE). METHODS:Patients (32 senile and 29 diabetic cataract) undergoing standardized phacoemul...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2014.949779
更新日期:2016-01-01 00:00:00
abstract::Purpose: To analyse the association between skin score with corneal biomechanics and dry eye tests in systemic sclerosis (SSc). Methods: 112 cases (limited SSc (lcSSc), n=50; diffuse SSc (dcSSc), n=32; controls, n=30) were included in the study. Corneal hysteresis (CH), corneal resistance factor (CRF), Schirmer 1, 2 ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1501496
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To evaluate morphology of the optic nerve head and visual field in AIDS patients without retinitis. METHODS:One randomly selected eye from 246 patients with AIDS without retinitis was evaluated from prospective multicenter Longitudinal Studies of Ocular Complications of AIDS. Stereo fundus photographs of OHN a...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.3109/09273948.2012.694552
更新日期:2012-10-01 00:00:00
abstract::Uveitis is an intraocular inflammation that can be caused by infection, autoimmune disease, trauma or malignancy. It is a serious cause of visual handicap and therapy is targeted at: removal of possible infectious agents, the immunological processes that lead to or sustain the inflammation and finally to prevent or tr...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273949609079654
更新日期:1996-01-01 00:00:00
abstract::Purpose: To summarize the characteristics of endogenous fungal endophthalmitis (EFE) after genitourinary procedures. Methods: Medical records of patients diagnosed with EFE after genitourinary procedures from a single center during a 6-year period were reviewed. Results: Nineteen eyes of 15 patients were included. The...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1465100
更新日期:2019-01-01 00:00:00
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journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940802187466
更新日期:2008-07-01 00:00:00
abstract:PURPOSE:To describe a case of sympathetic ophthalmia following vitrectomy for endophthalmitis after an intravitreal injection of bevacizumab. DESIGN:Retrospective case report. METHODS:An 84-year-old male developed sympathetic ophthalmia 4 months after vitrectomy for endophthalmitis following an intravitreal injection...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940802409951
更新日期:2008-09-01 00:00:00
abstract:PURPOSE:To establish how much uveitis patients know about their own condition and to investigate the contribution of demographic factors to that knowledge. METHODS:A self-designed questionnaire, comprising 20 questions about uveitis, was distributed to 200 consecutive patients attending a uveitis clinic. The questionn...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2016.1175638
更新日期:2017-12-01 00:00:00
abstract:PURPOSE:To investigate the changes of effector-related phenotypic markers and the natural killer (NK)-like effector functions of CD8(bright)CD56+ T cells in patients with Behçet uveitis after combined cyclosporine and prednisone (Cs/Pd) treatment. METHODS:Ten patients with active Behçet panuveitis and 10 healthy contr...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940600966616
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVE:To investigate serum inflammatory factors in patients with idiopathic choroidal vascularization (CNV), including vascular endothelial growth factor (VEGF), tumor necrosis factor alpha (TNFα), Interleukin1-beta (IL1-β), IgG, IgA, IgM, IgE, 50% hemolytic unit of complement (CH50), complement C3, complement C4 a...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2010.483315
更新日期:2010-10-01 00:00:00
abstract:PURPOSE:To report the presentations of syphilitic uveitides in Singapore. METHODS:Retrospective noncomparative observational case series of 18 eyes from 12 patients with ocular syphilis between 2004 and 2009. RESULTS:Patients were mainly male (91.7%). Median age was 49.5 (24-84) years. Initial visual acuity varied fr...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2013.829106
更新日期:2014-02-01 00:00:00
abstract::Experimental autoimmune uveoretinitis (EAU) induced by immunization of male Lewis rats with bovine S-antigen (S-Ag) is prevented by injection of S-Ag into the testis prior to immunization. This protection of animals is due to the induction of systemic immunotolerance or immunosuppression, which the authors designate o...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273949509085041
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:To assess correlation for anterior chamber flare grading between clinicians with different levels of experience and with semi-automated flare reading in a cohort of patients with heterogeneous uveitic entities. METHODS:Fifty-nine observations from 36 patients were recorded and analyzed for statistical associat...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2014.990042
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:To describe the medical treatment of severe ocular hypotony in HIV-seropositive patients with cytomegalovirus retinitis and cidofovir-associated uveitis. PATIENTS AND METHODS:Two HIV-seropositive patients with cytomegalovirus retinitis and cidofovir-associated uveitis complicated by severe ocular hypotony we...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1076/ocii.9.3.211.3968
更新日期:2001-09-01 00:00:00
abstract::Background Uveal effusion is a rare disease that is characterized by exudative detachment of the ciliary body and choroid. Herein, we report a rare case of uveal effusion associated with viral encephalitis, which resolved following the treatment of the viral encephalitis and administration of corticosteroids. Case pre...
journal_title:Ocular immunology and inflammation
pub_type: 信件
doi:10.1080/09273948.2020.1797110
更新日期:2020-08-20 00:00:00