Ocular Whipple Disease: Report of Three Cases.

Abstract:

:Purpose: To emphasize the different manifestations of ocular involvement in Whipple disease with challenge in establishing the diagnosis as clinical, laboratory, and histological features could mimic other uveitis entities. Methods: Case reports of three patients. Results: The first patient was an African male suffering from a chronic bilateral keratoconjunctitivitis that was initially misdiagnosed as a chronic allergic conjunctivitis. The second patient was an Italian female who presented with bilateral vitritis, whereas the third patient was an Italian male suffering from a chronic bilateral panuveitis. The diagnosis of ocular Whipple in the first and third case was made by a positive T. whipplei PCR from the ocular specimen, and the second patient had detection of T. whipplei from extraocular sites. Conclusions: Whipple disease can have protean manifestations in the eye including an isolated ocular surface involvement manifested as keratitis.

journal_name

Ocul Immunol Inflamm

authors

Testi I,Tognon MS,Gupta V

doi

10.1080/09273948.2018.1518461

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

1117-1120

issue

7

eissn

0927-3948

issn

1744-5078

journal_volume

27

pub_type

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