Abstract:
PURPOSE:To describe the clinical presentations of inflammatory choroidal neovascular membranes (CNVMs) and factors leading to their delayed diagnosis. METHODS:Retrospective analysis of chart records and digital images of 60 patients (73 eyes) with inflammatory CNVM (January 1998 to December 2013) to obtain demographic and clinical details, particularly the time of the first documentation of inflammatory CNVM by the uveitis specialist, time of its actual appearance on digital images, and the earliest clinical indicators of a CNVM. RESULTS:In total, 14 (19.2%) eyes had a delayed diagnosis of inflammatory CNVMs, of which five developed significant visual loss. The earliest clinical indicators of CNVM that were overlooked initially due to their subtle appearance, included a tiny subretinal hemorrhage (five eyes), peripapillary halo/fluid/scar (eight eyes), and a subfoveal scar (one eye). The causes of uveitis in these eyes included Vogt-Koyanagi-Harada disease (five eyes, 35.7%), tubercular uveitis (five eyes, 35.7%), idiopathic (three eyes, 21.4%), and sympathetic ophthalmia (one eye, 7.1%). Presence of significant background fundus scarring, sunset glow fundus, visually significant cataract, poorly dilating pupil, media haze due to vitritis, cystoid macular edema, and multiple chorioretinal scars in these eyes probably predisposed to delayed detection of an underlying CNVM. CONCLUSIONS:A high index of suspicion and comparison of serial fundus photographs to identify the earliest clues of inflammatory CNVMs are important to prevent diagnostic delays and poorer outcomes.
journal_name
Ocul Immunol Inflammjournal_title
Ocular immunology and inflammationauthors
Bansal R,Bansal P,Gupta A,Gupta V,Dogra MR,Singh R,Katoch Ddoi
10.3109/09273948.2016.1160128subject
Has Abstractpub_date
2017-08-01 00:00:00pages
554-562issue
4eissn
0927-3948issn
1744-5078journal_volume
25pub_type
杂志文章abstract:PURPOSE:To determine the prevalence of viral infections in patients with hypertensive anterior uveitis in Thailand from polymerase chain reaction (PCR) of aqueous humor. METHODS:Thirty-one patients with anterior uveitis with intraocular pressure (IOP) above 25 mmHg were included for PCR analysis for cytomegalovirus (C...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1678651
更新日期:2020-05-18 00:00:00
abstract:PURPOSE:To report the visual field changes in patients with serpiginous choroiditis as seen in a referral clinic in India. METHODS:A retrospective noncomparative case series was conducted. Twenty-nine eyes of 17 patients who were diagnosed with serpiginous choroiditis were included in the study. Clinical findings were...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2014.902473
更新日期:2014-10-01 00:00:00
abstract:PURPOSE:Tear lysozyme and tear lactoferrin are enzymes synthesized by the lacrimal gland. Their concentration in human tears reflects tear gland function. Tear gland dysfunction can lead to ocular surface disease. We developed a colorimetric lysozyme assay. The objective of this study was to determine the diagnostic po...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1076/ocii.7.1.7.8108
更新日期:1999-03-01 00:00:00
abstract:PURPOSE:To present fundus autofluorescence (FAF), indocyanine green angiography (ICGA), and microperimetry (MP) findings of a patient with multiple evanescent white dot syndrome (MEWDS). METHODS:Observational case report. RESULTS:A 30-year-old woman with blurry vision was referred for evaluation. Fundus examination r...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940802026060
更新日期:2008-05-01 00:00:00
abstract::Purpose: To assess changes in aqueous humor (AH) levels of cytokines following dexamethasone intravitreal implant (DEX) injection for diabetic macular edema (DME).Methods: Sixteen DME and cataract cases series study. Anterior chamber AH sampling was performed at baseline at DEX injection time (T1), cataract surgery 8 ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1636095
更新日期:2019-01-01 00:00:00
abstract::Herpes simplex virus, varicella zoster virus, human cytomegalovirus, and rubella virus are the most common causes of virus-induced anterior uveitis. They can present in a variety of entities not only with typical but also overlapping clinical characteristics. These viral infections are commonly associated with ocular ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:10.1080/09273948.2018.1439069
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:To describe the clinical outcome of patients with juvenile idiopathic arthritis (IA)-associated chronic iridocyclitis unresponsive to conventional therapy, in whom inflammation was eventually controlled using immunomodulatory therapy (IMT), and to determine if patients treated early with IMT have better visual ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940590951061
更新日期:2005-09-01 00:00:00
abstract::Purpose: To present the ocular findings of the members of a family that has the diagnosis of Muckle Wells syndrome, a form of cryopyrin associated periodic syndrome (CAPS).Materials and Methods: Nine patients with MWS were included in this study. Each study participant underwent a systemic evaluation, comprehensive op...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1552305
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:To investigate the incidence and risk factors of secondary glaucoma among uveitis patients. METHODS:Retrospective review of medical records of 642 patients (1220 eyes). RESULTS:Glaucoma was diagnosed in 169 (13.9%) eyes and was most common in eyes with anterior uveitis (19.1%) (p < 0.001). HLA-B27-positive an...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2015.1047036
更新日期:2016-10-01 00:00:00
abstract::Intraocular manifestations of tuberculosis (TB) are rare, but TB infection is common worldwide, especially in developing economies, and in immigrant populations and immunocompromised patients in developed nations. The current review focuses on the clinical characteristics and diagnostic modalities useful in the diagno...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:10.3109/09273948.2010.489729
更新日期:2010-08-01 00:00:00
abstract:PURPOSE:To investigate the safety and efficacy of daclizumab (Zenapax, humanized anti-Tac, HAT) in controlling the ocular manifestations of Behçet's disease. DESIGN:Randomized, placebo-controlled, double-masked clinical trial. PARTICIPANTS:Seventeen participants with Behçet's disease experiencing at least two prior o...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,随机对照试验
doi:10.1080/09273940701299370
更新日期:2007-03-01 00:00:00
abstract:PURPOSE:To evaluate the clinical outcome and safety of adalimumab in patients with Vogt-Koyanagi-Harada (VKH) disease. METHODS:VKH patients treated with adalimumab seen at the University of Buenos Aires were reviewed. Main outcome measures were visual acuity, anterior segment inflammation, optic nerve inflammation (ON...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2016.1236969
更新日期:2018-01-01 00:00:00
abstract::Purpose: To describe the long-term clinical outcomes in a cohort of uveitic eyes treated with the intravitreal dexamethasone implant (Ozurdex; Allergan, Inc).Methods: Seventy-nine (63 patients) receiving 134 implant injections over 82 months were included. Indication, visual acuity (VA), intraocular pressure (IOP), vi...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1578380
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:To analyze the diagnostic predictive ability of clinical variables. METHODS:Demographic and clinical variables of 172 serologically proven leptospiral uveitis patients were compared with 200 controls of non-leptospiral uveitis. Multiple logistic regression analysis identified diagnostic predictors. A receiver ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2016.1217341
更新日期:2018-01-01 00:00:00
abstract::A 45-year-old man was diagnosed with diffuse large B-cell lymphoma stage IV which was confirmed by celiac lymph node biopsy. He subsequently completed six cycles of R-CHOP chemotherapy. Six months later, he presented with panuveitis OU with positive relative afferent pupillary defect OD. OCT revealed hyper-reflective ...
journal_title:Ocular immunology and inflammation
pub_type: 信件
doi:10.1080/09273948.2020.1800050
更新日期:2020-09-24 00:00:00
abstract::We report on a 22-years-old Thai male patient with congenital HIV infection. Due to his non-adherence to antiretroviral treatment he developed disseminated Talaromyces marneffei infection and was treated with intravenous amphotericin B. Despite this treatment, he presented with bilateral granulomatous anterior uveitis...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1657468
更新日期:2020-10-02 00:00:00
abstract::Purpose: To identify the risk factors for the development of subretinal fibrosis (SRF) among patients with Vogt-Koyanagi-Harada (VKH) syndrome. Methods: In this case-control study, electronic clinical records from patients diagnosed with VKH syndrome who attended the Inflammatory Eye Disease Clinic at a tertiary care ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2020.1825750
更新日期:2020-10-06 00:00:00
abstract:PURPOSE:To assess the value of fluorine-18 fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) in patients with unexplained chronic uveitis. METHODS:Retrospective review of 19 (18)F-FDG PET scans. All patients had normal chest CT. In the final analysis, the authors used criteria similar to the criteria of ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940902788221
更新日期:2009-05-01 00:00:00
abstract::Acute anterior uveitis (AAU) is the commonest type of uveitis and HLA-B27 AAU is the most frequently recognized type of acute anterior uveitis and anterior uveitis overall. Recent evidence indicates that acute anterior uveitis is a heterogenous disease, is polygenic and is frequently associated with the spondyloarthro...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:10.3109/09273948.2016.1158283
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:To compare levels of selected mediators in serums and aqueous humor (AH) of type 2 diabetes mellitus cataract patients with senile cataract patients, and to determine their association with postoperative corneal edema (CE). METHODS:Patients (32 senile and 29 diabetic cataract) undergoing standardized phacoemul...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2014.949779
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:To report the pattern of uveitis in patients attending a tertiary uveitis service in Sydney, Australia. METHODS:The charts of patients seen between January 2009 and December 2015 were retrospectively reviewed. Data pertaining to patient demographics, eye examination on presentation, work-up and final diagnoses...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2016.1247871
更新日期:2017-01-01 00:00:00
abstract:AIM:The objective of this study is to describe the surgical outcomes of patients of HIV on HAART who underwent surgery for CMV retinitis related retinal detachment. METHOD AND MATERIALS:A retrospective analysis of the medical records of 40 eyes of 35 consecutive HIV positive patients who underwent surgical repair for ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,多中心研究
doi:10.3109/09273948.2014.999376
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:To report 2 cases of branch retinal artery occlusion (BRAO) associated with Behçet disease (BD). DESIGN:Small case series. METHODS:Review of two patients' charts, fluorescein angiography, and optical coherence tomography (OCT). RESULTS:The authors report two young patients, diagnosed with BD, who developed d...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2011.582219
更新日期:2011-08-01 00:00:00
abstract::Introduction: Uveitis is an important cause of blindness and ocular morbidity in the world. The patterns of uveitis have not been well characterized in sub-Saharan Africa. Purpose: To describe the characteristics of uveitis among patients presenting to Jimma University Department of Ophthalmology (JUDO) from July 2013...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1644348
更新日期:2020-10-02 00:00:00
abstract::Purpose: To review early withdrawal of immunomodulatory therapy (IMT) for birdshot retinochoroidopathy (BSRC). Design: Retrospective case-series of sixteen patients with Human-leukocyte-antigen-A29-positive BSRC treated with IMT ≥ 1 year and discontinued prior to achieving durable remission, observed ≥ 6 months off IM...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1506040
更新日期:2019-01-01 00:00:00
abstract::The authors present a polymerase chain reaction method for rapid and direct diagnosis of herpetic intraocular infections using small volume samples of intraocular fluid from 29 patients with various intraocular inflammatory diseases and 24 controls with senile cataract. Of six patients with early acute retinal necrosi...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273949309086545
更新日期:1993-01-01 00:00:00
abstract::Behçet's disease is the most frequently encountered form of endogenous uveitis in Japan. The authors examined the clinical manifestations in cases with Behçet's disease over six years (1987-1992), and compared the results with those of a previous study (1978-1983). In the more recent study the number of new patients w...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273949509069117
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:To investigate the safety of pharmaceutically compounded syringes for intravitreal administration of anti-vascular endothelial growth factor (anti-VEGF) drugs. METHODS:Single center, retrospective chart review. From 2015 to 2019, Oslo University Hospital, Norway gradually implemented pharmaceutical compounding...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2020.1820530
更新日期:2020-10-07 00:00:00
abstract:PURPOSE:To compare the contamination rate between 27-gauge and 30-guage needles used for intravitreal injection (IVT). METHODS:Patients undergoing IVT injections were enrolled prospectively. Injections were performed with 27- or 30-gauge needles. All needle tips were collected and placed in brain-heart infusion broth....
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2013.801988
更新日期:2013-10-01 00:00:00
abstract:PURPOSE:To describe a case of orbital sarcoidosis manifesting with enophthalmos. METHODS:A 60-year-old woman presented with right enophthalmos. She had a palpable mass in her anterior orbit inferiorly. She underwent a complete ophthalmic evaluation, magnetic resonance imaging, and histopathologic examination. RESULTS...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940601038589
更新日期:2006-12-01 00:00:00