Abstract:
:Purpose: To evaluate multimodal imaging findings in longitudinal follow-up of a patient with presumed tuberculous serpiginous-like choroiditis (TB-SLC). Method: We evaluated multimodal imaging in a 62-year-old male with TB-SLC. Correlation between optical coherence tomography angiography (OCTA), swept-source OCT (SS-OCT) and fundus autofluorescence (FAF) at defined disease stages and evolution of observed imaging descriptors during long-term follow-up has not been previously reported. Results: OCTA of the active lesion demonstrated defined areas of choriocapillaris hypoperfusion, suggesting inflammatory vascular occlusive pathology. Over 9-month follow-up, OCTA illustrated sequential improvement in choriocapillaris flow, suggesting vascular remodeling. This correlated with progressive change in FAF signal and transition to diffuse hypoautofluorescence. SS-OCT demonstrated focal choroidal thickening and retinal pigment epithelium elevation in acute phase and resolution in time. Conclusion: Multimodal imaging, particularly novel non-invasive technologies such as OCTA and SS-OCT, improves our understanding of the pathogenesis and evolution of disease in TB-SLC.
journal_name
Ocul Immunol Inflammjournal_title
Ocular immunology and inflammationauthors
Wang H,Tan SZ,Aslam T,Jones NP,Steeples LRdoi
10.1080/09273948.2018.1501497subject
Has Abstractpub_date
2019-01-01 00:00:00pages
1149-1153issue
7eissn
0927-3948issn
1744-5078journal_volume
27pub_type
杂志文章abstract:PURPOSE:To compare clinical characteristics and visual prognosis between HLA-B27-associated uveitis patients with and without posterior segment involvement. METHODS:Medical records of 78 patients with HLA-B27-associated uveitis were retrospectively analyzed. RESULTS:Neither demographic nor clinical characteristics we...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940802553261
更新日期:2009-01-01 00:00:00
abstract::Purpose: To describe tuberculous uveitis (TU) presenting as a bullous retinal detachment (RD) and to perform a comprehensive literature review on TU with similar features. Methods: Observational case report and systematic literature review. Results: An 84-year-old woman presented with bilateral granulomatous uveitis a...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1485958
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:The study was to evaluate the diagnostic efficacy of nested polymerase chain reaction (nPCR) using primers targeting B1 gene of Toxoplasma gondii (T. gondii) with Witmer Desmonts coefficient (WDC) technique in intraocular fluids of clinically suspected toxoplasma retino choroiditis (TRC) patients. MATERIALS ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940500545692
更新日期:2006-04-01 00:00:00
abstract:PURPOSE:To describe scleral changes in chronic VKH. METHODS:Medical records of patients with chronic VKH were retrospectively reviewed. Change of scleral architecture was defined as progressive posterior bowing on OCT, axial length elongation, and/or increased myopia more than -1.0 D, not explicable by other etiologie...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2015.1057600
更新日期:2017-02-01 00:00:00
abstract:PURPOSE:To assess correlation for anterior chamber flare grading between clinicians with different levels of experience and with semi-automated flare reading in a cohort of patients with heterogeneous uveitic entities. METHODS:Fifty-nine observations from 36 patients were recorded and analyzed for statistical associat...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2014.990042
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:To compare histopathological and biochemical effects of the anti-TNF-alpha drugs adalimumab and infliximab in a uveitis experimental model. METHODS:Histopathological evaluation was performed 24 h after endotoxin (200 microg into the footpad) and drug administration, as well as biochemical analysis of oxidative...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273940903521964
更新日期:2010-06-01 00:00:00
abstract::We report on a 22-years-old Thai male patient with congenital HIV infection. Due to his non-adherence to antiretroviral treatment he developed disseminated Talaromyces marneffei infection and was treated with intravenous amphotericin B. Despite this treatment, he presented with bilateral granulomatous anterior uveitis...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1657468
更新日期:2020-10-02 00:00:00
abstract:PURPOSE:To describe a case of severe central retinal vein occlusion (CRVO) in a young patient, in whom intensive immunosuppressive therapy improved the clinical outcome. CASE REPORT:A 35-year-old men presented with a first episode of CRVO in his right eye in 1990. Despite corticosteroids and laser treatment, rubeotic ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1076/ocii.10.2.141.13981
更新日期:2002-06-01 00:00:00
abstract:PURPOSE:Longitudinal evaluation of acute exudative polymorphous paraneoplastic vitelliform maculopathy (AEPPVM) following diagnosis and treatment of metastatic melanoma. METHODS:Case report of a 47-year-old male with unknown primary metastatic melanoma and AEPPVM monitored before and during melanoma treatment using cl...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2020.1813782
更新日期:2020-10-06 00:00:00
abstract:PURPOSE:To evaluate multifocal evanescent white dot syndrome (MEWDS) patients with and without overlapping multifocal choroiditis (MFC). METHODS:Thirty-four patients diagnosed between November 2008 and August 2018 at 2 hospitals were retrospectively reviewed. Multimodal imaging including optical coherence tomography a...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2020.1795206
更新日期:2020-09-01 00:00:00
abstract::Introduction: Uveitic macular edema (UME) is a significant cause of visual impairment in all uveitis types. Methods: Reports that were cited in the MEDLINE database, that analyzed the effectiveness of biologics for UME in at least five patients, with a minimum follow-up of 3 months, published prior to April 1, 2019 we...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1709648
更新日期:2020-11-16 00:00:00
abstract::Introduction: Uveitis is an important cause of blindness and ocular morbidity in the world. The patterns of uveitis have not been well characterized in sub-Saharan Africa. Purpose: To describe the characteristics of uveitis among patients presenting to Jimma University Department of Ophthalmology (JUDO) from July 2013...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1644348
更新日期:2020-10-02 00:00:00
abstract::Purpose: To analyze the clinical features and long-term prognosis of uveitis in tubulointerstitial nephritis and uveitis (TINU) syndrome in a cohort of Chinese patients. Methods: A total of 32 patients with TINU syndrome between 2000 - 2016 were analyzed retrospectively. Results: Mild anterior inflammation was observe...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2017.1394469
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To report a case of ocular Gnathostomiasis presenting as branch retinal artery occlusion. METHOD:Observational case report. RESULT:A 22-year-old Asian woman presented to her ophthalmologist with redness, tearing, and decreased vision in her left eye. Examination revealed anterior uveitis and branch retinal ar...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2020.1820532
更新日期:2020-09-29 00:00:00
abstract:PURPOSE:To evaluate corneal parameters of scleroderma (SC) patients by Pentacam-HR. METHODS:Twenty-two eyes of 22 SC patients and 33 eyes of 33 control subjects were enrolled. All participants underwent Pentacam (Pentacam-HR, Oculus, Germany) evaluation. Both SC and control groups were divided into two subgroups as dr...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2015.1115079
更新日期:2017-04-01 00:00:00
abstract::Purpose: To identify the risk factors for the development of subretinal fibrosis (SRF) among patients with Vogt-Koyanagi-Harada (VKH) syndrome. Methods: In this case-control study, electronic clinical records from patients diagnosed with VKH syndrome who attended the Inflammatory Eye Disease Clinic at a tertiary care ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2020.1825750
更新日期:2020-10-06 00:00:00
abstract::Purpose: To describe the long-term clinical outcomes in a cohort of uveitic eyes treated with the intravitreal dexamethasone implant (Ozurdex; Allergan, Inc).Methods: Seventy-nine (63 patients) receiving 134 implant injections over 82 months were included. Indication, visual acuity (VA), intraocular pressure (IOP), vi...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1578380
更新日期:2020-01-01 00:00:00
abstract::The treatment of articular and extra-articular manifestations associated with HLA-B27 has undergone dramatic changes over the past two decades, mainly as a consequence of the introduction of biologic agents and in particular anti-tumor necrosis factor α (anti-TNFα) agents. Uveitis is known to be the most frequent extr...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:10.1080/09273948.2016.1234625
更新日期:2017-04-01 00:00:00
abstract:PURPOSE:To report a patient with submacular hemorrhage due to retinal angiomatous proliferation (RAP) in tubercular retinal vasculitis (TRV). METHODS:Case report. RESULTS:We report a 33-year-old Asian Indian patient of TRV presenting with capillary non-perfusion areas, submacular hemorrhage and venous loops. The pati...
journal_title:Ocular immunology and inflammation
pub_type: 信件
doi:10.1080/09273948.2020.1803363
更新日期:2020-09-25 00:00:00
abstract:PURPOSE:Manifestations of Systemic lupus erythematosus are protean and the eye can get affected in more than a third of the cases. This study was conducted to evaluate the spectrum of ocular manifestation among Nepalese patients diagnosed with Systemic lupus erythematosus. METHODS:In this hospital based cross-sectiona...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2011.610023
更新日期:2011-12-01 00:00:00
abstract::Purpose: To report a case of cystoid macular edema (CME) secondary to juvenile idiopathic arthritis (JIA)-associated uveitis. Case report: 26-year-old female patient presented with CME in both eyes. CME became refractory and TCZ-IV was initiated. After 12 infusions was stopped because grade 1 neuropenia developed. On ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2019.1644350
更新日期:2019-10-07 00:00:00
abstract::Purpose: To present the ocular findings of the members of a family that has the diagnosis of Muckle Wells syndrome, a form of cryopyrin associated periodic syndrome (CAPS).Materials and Methods: Nine patients with MWS were included in this study. Each study participant underwent a systemic evaluation, comprehensive op...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1552305
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:To report a rare case of intermediate uveitis following rubella infection in pregnancy. DESIGN:Case report. METHODS:A 35-year-old pregnant woman, at 24 weeks of gestation, presented with sudden floaters and blurring of vision of the left eye. Ocular examination revealed vitritis 1-2+ with no retinal involveme...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2011.555593
更新日期:2011-06-01 00:00:00
abstract::Purpose: To analyse the association between skin score with corneal biomechanics and dry eye tests in systemic sclerosis (SSc). Methods: 112 cases (limited SSc (lcSSc), n=50; diffuse SSc (dcSSc), n=32; controls, n=30) were included in the study. Corneal hysteresis (CH), corneal resistance factor (CRF), Schirmer 1, 2 ...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2018.1501496
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To study the safety and efficacy of intravitreal injection of dexamethasone implant in the management of posterior segment involvement in tubercular uveitis (TBU). METHODS:In this study, retrospective analysis of safety and efficacy of intravitreal injection of dexamethasone implant for various indications suc...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2017.1400074
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:Primary vitreoretinal lymphomas (PVRL) pose a major diagnostic challenge, especially in the countries with a high prevalence of infectious variety of uveitis. The present study aims to report the clinical characteristics and diagnostic difficulties in patients with PVRL in an Indian Population. METHODS:Retrosp...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2016.1139731
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:To investigate the changes of effector-related phenotypic markers and the natural killer (NK)-like effector functions of CD8(bright)CD56+ T cells in patients with Behçet uveitis after combined cyclosporine and prednisone (Cs/Pd) treatment. METHODS:Ten patients with active Behçet panuveitis and 10 healthy contr...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940600966616
更新日期:2006-10-01 00:00:00
abstract::Purpose: To emphasize the different manifestations of ocular involvement in Whipple disease with challenge in establishing the diagnosis as clinical, laboratory, and histological features could mimic other uveitis entities. Methods: Case reports of three patients. Results: The first patient was an African male sufferi...
journal_title:Ocular immunology and inflammation
pub_type: 信件
doi:10.1080/09273948.2018.1518461
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To report outcomes and assess structural changes in the retina in patients with severe endophthalmitis. METHODS:Retrospective, nonrandomized, interventional case series at a tertiary referral centre. Spectral domain optical coherence tomography (OCT) images of both eyes were acquired at least 5 months after pa...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2014.949780
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Equine uveitis is a spontaneous disorder of horses that can serve as a model for the study of human uveitis. Although the initial presentation is that of an anterior uveitis, retinal involvement has been noted in some cases. We report here the immunohistopathology of retinas from horses with uveitis. METHOD...
journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1076/ocii.6.4.239.4026
更新日期:1998-12-01 00:00:00