Comparative Analysis of Anterior Chamber Flare Grading between Clinicians with Different Levels of Experience and Semi-automated Laser Flare Photometry.

Abstract:

PURPOSE:To assess correlation for anterior chamber flare grading between clinicians with different levels of experience and with semi-automated flare reading in a cohort of patients with heterogeneous uveitic entities. METHODS:Fifty-nine observations from 36 patients were recorded and analyzed for statistical association. In each patient, flare was assessed objectively using the Kowa FM-700 laser flare photometer, and subjective masked grading by two clinicians was performed. RESULTS:The study demonstrated disparity in flare readings between clinical graders with one step disagreement in clinical grading in 26 (44.06%) eyes (p < 0.001) and concordance between the flare readings by experienced grader and flare photometry. After review of semi-automated flare readings, management was changed in 11% of the patients. CONCLUSION:Laser flare photometry can be a valuable tool to remove the observer bias in grading flare for selected cohort of uveitis patients. It can be further applied to titrate therapy in intraocular inflammation.

journal_name

Ocul Immunol Inflamm

authors

Agrawal R,Keane PA,Singh J,Saihan Z,Kontos A,Pavesio CE

doi

10.3109/09273948.2014.990042

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

184-93

issue

2

eissn

0927-3948

issn

1744-5078

journal_volume

24

pub_type

杂志文章
  • Combined low dose cyclosporine and prednisone down-regulate natural killer cell-like effector functions of CD8brightCD56+ T cells in patients with active Behçet uveitis.

    abstract:PURPOSE:To investigate the changes of effector-related phenotypic markers and the natural killer (NK)-like effector functions of CD8(bright)CD56+ T cells in patients with Behçet uveitis after combined cyclosporine and prednisone (Cs/Pd) treatment. METHODS:Ten patients with active Behçet panuveitis and 10 healthy contr...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940600966616

    authors: Ahn JK,Park YG,Park SW,Yoon KC,Yu HG,Chung H

    更新日期:2006-10-01 00:00:00

  • The Role of Dexamethasone Implant in the Management of Tubercular Uveitis.

    abstract:PURPOSE:To study the safety and efficacy of intravitreal injection of dexamethasone implant in the management of posterior segment involvement in tubercular uveitis (TBU). METHODS:In this study, retrospective analysis of safety and efficacy of intravitreal injection of dexamethasone implant for various indications suc...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2017.1400074

    authors: Agarwal A,Handa S,Aggarwal K,Sharma M,Singh R,Sharma A,Agrawal R,Sharma K,Gupta V

    更新日期:2018-01-01 00:00:00

  • Dark spot in fibrinous central serous chorioretinopathy masquerading choroiditis.

    abstract:PURPOSE:The authors observed that eyes with acute fibrinous central serous chorioretinopathy (CSC) masquerading active choroiditis had a "dark spot" within the yellow fibrinous deposit. The present study aims to describe this sign as a clinical indicator of acute serofibrinous exudative detachment, thus helping to diff...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2013.765015

    authors: Parchand S,Gupta V,Gupta A,Dogra MR,Singh R,Sharma A

    更新日期:2013-06-01 00:00:00

  • Sympathetic ophthalmia following vitrectomy for endophthalmitis after intravitreal bevacizumab.

    abstract:PURPOSE:To describe a case of sympathetic ophthalmia following vitrectomy for endophthalmitis after an intravitreal injection of bevacizumab. DESIGN:Retrospective case report. METHODS:An 84-year-old male developed sympathetic ophthalmia 4 months after vitrectomy for endophthalmitis following an intravitreal injection...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940802409951

    authors: Sisk RA,Davis JL,Dubovy SR,Smiddy WE

    更新日期:2008-09-01 00:00:00

  • Optical Coherence Tomography Imaging of Presumed Sarcoid Retinal and Optic Nerve Nodules.

    abstract:PURPOSE:To characterize nodular lesions of the retina and optic nerve with spectral-domain optical coherence tomography (SD-OCT) in patients with sarcoidosis. METHODS:This is a retrospective series of 6 eyes from 5 patients with an established diagnosis of sarcoidosis, with clinically detected nodules of the optic ner...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2014.971972

    authors: Goldberg NR,Jabs DA,Busingye J

    更新日期:2016-06-01 00:00:00

  • Association of Propionibacterium acnes endophthalmitis with HLA-DQw5.

    abstract:BACKGROUND:An HLA-DQ1 association has been suspected in patients who develop Propionibacterium acnes endophthalmitis following cataract surgery. New techniques exist which may help to define this association. MATERIALS AND METHODS:Patients with culture-proven P. acnes endophthalmitis following cataract surgery were HL...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273949609069124

    authors: Davis JL,Winward KR,Lonardo EC,Nussenblatt RB,Meisler DM,Lee TD

    更新日期:1996-01-01 00:00:00

  • Sjögren's syndrome (SS) and Epstein-Barr virus (EBV) reactivation.

    abstract::Recent reports have shown that dry eye in Sjögren's syndrome (SS) is associated with reactivation of Epstein-Barr virus (EBV) in lacrimal glands. However, the number of patients examined were few and it has not been determined whether dry eye in the absence of SS is also related to EBV reactivation. The authors exam...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273949409057066

    authors: Toda I,Ono M,Fujishima H,Tsubota K

    更新日期:1994-01-01 00:00:00

  • Association between Skin Thickness Measurements with Corneal Biomechanical Properties and Dry Eye Tests in Systemic Sclerosis.

    abstract::Purpose: To analyse the association between skin score with corneal biomechanics and dry eye tests in systemic sclerosis (SSc). Methods: 112 cases (limited SSc (lcSSc), n=50; diffuse SSc  (dcSSc), n=32; controls, n=30) were included in the study. Corneal hysteresis (CH), corneal resistance factor (CRF), Schirmer 1, 2 ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2018.1501496

    authors: Ayhan Z,Kaya M,Ozturk T,Arikan G,Birlik M

    更新日期:2019-01-01 00:00:00

  • Clinical Course and Outcomes of Pediatric Tubercular Uveitis in North India.

    abstract:PURPOSE:To analyze the clinical features, course, management, and outcomes of tubercular (TB) uveitis in the pediatric population and assess the response to anti-tubercular therapy (ATT). METHODS:Hospital records of children (≤16 years) from a large tertiary-care institute between January 2001 and December 2015 were r...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2017.1296579

    authors: Kaur S,Aggarwal K,Agarwal A,Suri D,Gupta A,Singh R,Bansal R,Singh S,Singh N,Gupta A,Gupta V

    更新日期:2018-01-01 00:00:00

  • Use of PCR in endophthalmitis.

    abstract::In eyes with suspected endophthalmitis, early diagnosis and appropriate treatment have been noted to be associated with a better visual outcome. Currently, however, confirmation of the diagnosis of endophthalmitis (bacterial and/or fungal) is dependent on conventional techniques of microbiological isolation of organis...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:

    authors: Okhravi N,Adamson P,Lightman S

    更新日期:2000-09-01 00:00:00

  • Bacterial contamination of needles used for intravitreal injections: comparison between 27-gauge and 30-gauge needles.

    abstract:PURPOSE:To compare the contamination rate between 27-gauge and 30-guage needles used for intravitreal injection (IVT). METHODS:Patients undergoing IVT injections were enrolled prospectively. Injections were performed with 27- or 30-gauge needles. All needle tips were collected and placed in brain-heart infusion broth....

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2013.801988

    authors: Tufan HA,Vural A,Gencer B,Kara S,Arikan S,Yuksel E

    更新日期:2013-10-01 00:00:00

  • Mucormycosis Endophthalmitis in a Silicone Oil-Filled Eye of an Immunocompetent Patient.

    abstract::Purpose:: Fungal endophthalmitis following pars plana vitrectomy with silicone oil tamponade is an infrequent entity. Filamentous fungi like aspergillus are generally associated with endophthalmitis. Mucor is a rarely implicated pathogen in cases of endophthalmitis with only two reported cases in medical literature. B...

    journal_title:Ocular immunology and inflammation

    pub_type: 信件

    doi:10.1080/09273948.2018.1518462

    authors: Dogra M,Bhutani G,Gupta V

    更新日期:2019-01-01 00:00:00

  • The Role of QuantiFERON®-TB Gold and Tuberculin Skin Test as Diagnostic Tests for Intraocular Tuberculosis in HIV-Positive and HIV-Negative Patients in South Africa.

    abstract:PURPOSE:To compare QuantiFERON®-TB Gold and tuberculin skin testing as diagnostic tests for intraocular tuberculosis in HIV positive and negative patients. METHODS:A prospective study evaluating two different tests to help diagnose intraocular tuberculosis. RESULTS:Thirty-five of 106 patients (33.0%) were diagnosed w...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2017.1327078

    authors: Smit DP,Esterhuizen TM,Meyer D

    更新日期:2018-01-01 00:00:00

  • Tachykinins as enhancers of prostaglandin E2-induced intraocular inflammation.

    abstract::The effects of tachykinins on prostaglandin E2 (PGE2)-induced intraocular inflammation were investigated. PGE2 (0.01% or 0.1%) instillation induced iridal hyperemia and protein leakage into the aqueous humor in rabbits, but caused minimal miosis. Intravitreally injected substance P (SP) or neurokinin A (NKA), on the o...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1076/ocii.6.1.19.8080

    authors: Tsuji F,Hamada M,Shirasawa E

    更新日期:1998-03-01 00:00:00

  • Innate Immunity Biomarkers for Early Detection of Keratoconus.

    abstract::Purpose: To compare toll-like receptors 2 (TLR2) and 4 (TLR4) expression in cells of corneal and conjunctival epithelium between unilateral KC patients and control subjects. Methods: Prospective cross-sectional case-control study, including 50 unilateral KC patients and 20 control subjects. TLR2 and TLR4 expression wa...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2018.1511813

    authors: Malfeito M,Regueiro U,Pérez-Mato M,Campos F,Sobrino T,Lema I

    更新日期:2019-01-01 00:00:00

  • Changes in Scleral Architecture in Chronic Vogt-Koyanagi-Harada Disease.

    abstract:PURPOSE:To describe scleral changes in chronic VKH. METHODS:Medical records of patients with chronic VKH were retrospectively reviewed. Change of scleral architecture was defined as progressive posterior bowing on OCT, axial length elongation, and/or increased myopia more than -1.0 D, not explicable by other etiologie...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2015.1057600

    authors: Harada Y,Bhat P,Munk MR,Goldstein DA

    更新日期:2017-02-01 00:00:00

  • Immune recovery uveitis.

    abstract::Potent antiretroviral therapy can result in substantial improvement in the immune function of patients with AIDS. In some patients with preexisting cytomegalovirus (CMV) retinitis, a consequence of this improved immune function is increased intraocular inflammation. This phenomenon, termed 'immune recovery uveitis', i...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:10.1076/ocii.7.3.215.4010

    authors: Holland GN

    更新日期:1999-12-01 00:00:00

  • Optical coherence tomography for classification and clinical evaluation of macular edema in patients with uveitis.

    abstract:PURPOSE:To study use of optical coherence tomography (OCT) for macular edema in uveitis. METHODS:In total, 44 patients with uveitis and macular edema underwent OCT. Data obtained were correlated with anatomic type, duration of uveitis, and visual acuity (VA). RESULTS:Both cystoid macular edema (CME) and diffuse macul...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940802187466

    authors: Iannetti L,Accorinti M,Liverani M,Caggiano C,Abdulaziz R,Pivetti-Pezzi P

    更新日期:2008-07-01 00:00:00

  • Rubella-related intermediate uveitis in pregnancy--a rare presentation.

    abstract:PURPOSE:To report a rare case of intermediate uveitis following rubella infection in pregnancy. DESIGN:Case report. METHODS:A 35-year-old pregnant woman, at 24 weeks of gestation, presented with sudden floaters and blurring of vision of the left eye. Ocular examination revealed vitritis 1-2+ with no retinal involveme...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2011.555593

    authors: Thirupathy A,Tajunisah I

    更新日期:2011-06-01 00:00:00

  • Intensive immunosuppression treatment for central retinal vein occlusion in a young adult: a case report.

    abstract:PURPOSE:To describe a case of severe central retinal vein occlusion (CRVO) in a young patient, in whom intensive immunosuppressive therapy improved the clinical outcome. CASE REPORT:A 35-year-old men presented with a first episode of CRVO in his right eye in 1990. Despite corticosteroids and laser treatment, rubeotic ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1076/ocii.10.2.141.13981

    authors: Willermain F,Greiner K,Forrester JV

    更新日期:2002-06-01 00:00:00

  • Treatment of severe ocular hypotony in AIDS patients with cytomegalovirus retinitis and cidofovir-associated uveitis.

    abstract:OBJECTIVE:To describe the medical treatment of severe ocular hypotony in HIV-seropositive patients with cytomegalovirus retinitis and cidofovir-associated uveitis. PATIENTS AND METHODS:Two HIV-seropositive patients with cytomegalovirus retinitis and cidofovir-associated uveitis complicated by severe ocular hypotony we...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1076/ocii.9.3.211.3968

    authors: Accorinti M,Ciapparoni V,Pirraglia MP,Pivetti-Pezzi P

    更新日期:2001-09-01 00:00:00

  • Ocular hypertension associated with ocular sarcoidosis.

    abstract:PURPOSE:To report bilateral ocular hypertension in association with ocular sarcoidosis. METHODS:Case note review of patients with a diagnosis of sarcoidosis-related uveitis. RESULTS:The authors identified 5 patients who fulfilled the diagnostic criteria for ocular sarcoidosis and who had intraocular pressures of > 40...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940701732230

    authors: Mirza S,Saeed T,Murray PI

    更新日期:2007-11-01 00:00:00

  • Analysis of retinal findings of acute retinal necrosis using optical coherence tomography.

    abstract:PURPOSE:To analyze the retinal findings in patients with ARN, optical coherence tomography (OCT) was performed. METHODS:Seven patients (7 eyes) with ARN were studied using OCT. RESULTS:OCT images depicted highly reflective areas in the inner layers of the retina in all seven cases, corresponding with the yellowish-wh...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940600672198

    authors: Suzuki J,Goto H,Minoda H,Iwasaki T,Sakai J,Usui M

    更新日期:2006-06-01 00:00:00

  • The roles of T-lymphocyte subpopulations (CD4 and CD8), intercellular adhesion molecule-1 (ICAM-1), HLA-DR receptor, and mast cells in etiopathogenesis of pterygium.

    abstract:PURPOSE:The etiopathogenesis of pterygia is controversial. We wished to explore the effects of inflammatory cells and mediators such as T-lymphocyte subpopulations (CD4 and CD8), mast cells, intercellular adhesion molecule-1 (ICAM-1), and HLA-DR receptors on pterygium development. METHODS:Immunohistochemical stainings...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1076/ocii.11.2.115.15913

    authors: Beden U,Irkeç M,Orhan D,Orhan M

    更新日期:2003-06-01 00:00:00

  • Use of a high infusion rate to prevent posterior dislocation of fluocinolone acetonide implant during surgical removal.

    abstract:PURPOSE:To describe a strategy for reducing the risk of posterior dislocation of a fluocinolone implant during exchange or removal. DESIGN:Case report and in vitro model. METHODS:Description of a surgical case and an in vitro experiment evaluating the role of infusion pressure in maintaining implant stability in surg...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2011.553980

    authors: Wan W,Stewart JM

    更新日期:2011-06-01 00:00:00

  • Tacrolimus (FK506) in failed cyclosporin A therapy in endogenous posterior uveitis.

    abstract::Tacrolimus (FK506) is effective in Japanese endogenous posterior uveitis (EPU), but there is limited data on its role in refractory EPU where cyclosporin A (CsA) toxicity/resistance develops. This open prospective clinical study aimed to assess the efficacy and adverse effects of low-dose FK506 therapy in western pati...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1076/ocii.6.2.101.4051

    authors: Kilmartin DJ,Forrester JV,Dick AD

    更新日期:1998-06-01 00:00:00

  • Ophthalmic Shingles with Simultaneous Acute Retinal Necrosis in the Opposite Eye.

    abstract:PURPOSE:To report a case of acute retinal necrosis (ARN) occurring in the opposite eye to the ophthalmic shingles eruption. DESIGN:Case report. METHODS:Clinical examination and multimodal imaging review, including ultra-widefield photography and fluorescein angiography (FA). RESULTS:A 49-years-old man attended the U...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2020.1770298

    authors: Battista M,Marchese A,Bordato A,Bandello F,Modorati GM,Miserocchi E

    更新日期:2020-07-09 00:00:00

  • Atypical presentation of multiple evanescent white dot syndrome (MEWDS).

    abstract:PURPOSE:To present fundus autofluorescence (FAF), indocyanine green angiography (ICGA), and microperimetry (MP) findings of a patient with multiple evanescent white dot syndrome (MEWDS). METHODS:Observational case report. RESULTS:A 30-year-old woman with blurry vision was referred for evaluation. Fundus examination r...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940802026060

    authors: Yenerel NM,Kucumen B,Gorgun E,Dinc UA

    更新日期:2008-05-01 00:00:00

  • Glaucoma Secondary to Uveitis in Children in a Tertiary Care Referral Center.

    abstract::Purpose: To study outcome of secondary glaucoma in pediatric uveitis patients. Methods: Retrospective analysis of records of uveitis patients ≤16 years. Results: Of 182 pediatric uveitis patients, secondary glaucoma was seen in 48 patients (75 eyes, 26.23%) with female preponderance (F:M-29:19) . JIA was the most comm...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2017.1411517

    authors: Gautam Seth N,Yangzes S,Thattaruthody F,Singh R,Bansal R,Raj S,Kaushik S,Gupta V,Pandav SS,Ram J,Gupta A

    更新日期:2019-01-01 00:00:00

  • Uveitis with myasthenia gravis--a rare association.

    abstract:AIM:To report 2 cases of idiopathic anterior uveitis with coexistent myasthenia gravis. MATERIALS AND METHODS:Retrospective case reports. RESULTS:A 60-year-old male and a 40-year-old male presented with chronic nongranulomatous anterior uveitis of unknown etiology. The latter had a history of hypothyroidism. During f...

    journal_title:Ocular immunology and inflammation

    pub_type: 信件

    doi:10.3109/09273948.2012.726687

    authors: Babu K,Mukhopadhyay M,Murthy KR

    更新日期:2013-01-01 00:00:00