Abstract:
:The treatment of articular and extra-articular manifestations associated with HLA-B27 has undergone dramatic changes over the past two decades, mainly as a consequence of the introduction of biologic agents and in particular anti-tumor necrosis factor α (anti-TNFα) agents. Uveitis is known to be the most frequent extra-articular feature in HLA-B27-associated spondyloarthritides. Topical corticosteroids and cycloplegic agents remain the cornerstones of treatment. However, biologic therapy may be effective in the management of refractory or recurrent forms of uveitis. This review gives an update on the management of HLA-B27-associated ocular disorders with biologics, including anti-TNFα agents and non-anti-TNFα biologic modifier drugs. There is an emerging role for newer biologics targeting interleukin-12/23 and interleukin-17 for the treatment of spondyloarthritides but data on their efficacy on anterior uveitis are sparse.
journal_name
Ocul Immunol Inflammjournal_title
Ocular immunology and inflammationauthors
Gueudry J,Thorne JE,Bansie R,Braun J,van Hagen PM,Bodaghi Bdoi
10.1080/09273948.2016.1234625subject
Has Abstractpub_date
2017-04-01 00:00:00pages
169-178issue
2eissn
0927-3948issn
1744-5078journal_volume
25pub_type
杂志文章,评审abstract::Background Uveal effusion is a rare disease that is characterized by exudative detachment of the ciliary body and choroid. Herein, we report a rare case of uveal effusion associated with viral encephalitis, which resolved following the treatment of the viral encephalitis and administration of corticosteroids. Case pre...
journal_title:Ocular immunology and inflammation
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journal_title:Ocular immunology and inflammation
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journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940802409951
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journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
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更新日期:2021-01-28 00:00:00
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journal_title:Ocular immunology and inflammation
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doi:10.3109/09273948.2015.1015741
更新日期:2016-06-01 00:00:00
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journal_title:Ocular immunology and inflammation
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doi:10.3109/09273948.2016.1160128
更新日期:2017-08-01 00:00:00
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journal_title:Ocular immunology and inflammation
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journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2017.1375532
更新日期:2017-10-01 00:00:00
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journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,多中心研究
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journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273949609069124
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journal_title:Ocular immunology and inflammation
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更新日期:2013-12-01 00:00:00
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journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
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更新日期:1995-01-01 00:00:00
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journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.3109/09273948.2014.949780
更新日期:2014-12-01 00:00:00
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journal_title:Ocular immunology and inflammation
pub_type: 信件
doi:10.1080/09273948.2020.1754862
更新日期:2020-05-27 00:00:00
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doi:10.1080/09273948.2019.1709648
更新日期:2020-11-16 00:00:00
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journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273940802702587
更新日期:2009-07-01 00:00:00
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doi:10.3109/09273949709116890
更新日期:1997-09-01 00:00:00
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journal_title:Ocular immunology and inflammation
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更新日期:2014-10-01 00:00:00
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journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,多中心研究
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journal_title:Ocular immunology and inflammation
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journal_title:Ocular immunology and inflammation
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更新日期:2019-01-01 00:00:00
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journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
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更新日期:2018-01-01 00:00:00
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journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1076/ocii.7.1.7.8108
更新日期:1999-03-01 00:00:00
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journal_title:Ocular immunology and inflammation
pub_type: 杂志文章,评审
doi:10.1076/ocii.11.1.73.15576
更新日期:2003-03-01 00:00:00
abstract:PURPOSE:To show the current status of multimodal imaging and its role in supporting an early diagnosis of sympathetic ophthalmia. METHODS:The diagnosis is mainly clinical supported with ancillary investigations; mainly fluorescein angiography and others, including indocyanine angiography optical coherence tomography (...
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pub_type: 杂志文章,评审
doi:10.1080/09273948.2016.1255339
更新日期:2017-04-01 00:00:00
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journal_title:Ocular immunology and inflammation
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更新日期:2019-09-30 00:00:00
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journal_title:Ocular immunology and inflammation
pub_type: 杂志文章
doi:10.1080/09273948.2016.1217341
更新日期:2018-01-01 00:00:00
abstract::Purpose: The purpose of the study is to quantify aqueous flare using laser flare photometry (LFM) in patients undergoing 25-G pars plana vitrectomy (PPV) and assess the need for postoperative topical corticosteroid administration . Methods: Prospective evaluation of 50 eyes (50 patients) was performed using LFM until ...
journal_title:Ocular immunology and inflammation
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更新日期:2019-01-01 00:00:00