Postmortem effect of pentobarbital anesthetic on survival of adult cortical neurons in primary culture.

abstract：:Multiple-unit activity (MUA) in the agranular medial prefrontal cortex (PFC) was recorded in conscious rabbits during a classical conditioning procedure involving repeated pairings of a 4-s tone conditioned stimulus (CS) with eye shock. Prior to behavioral training, significant tone-evoked increases in prefrontal MUA ...

journal_title：Brain research

authors： Gibbs CM,Powell DA

更新日期：1988-02-23 00:00:00

abstract：:Stroke is the major cause of acquired epilepsy in the adult population. The mechanisms of ischemia-induced epileptogenesis are not completely understood, but glutamate is associated with both ischemia-induced injury and epileptogenesis. The objective of this study was to develop an in vitro model of epileptogenesis in...

journal_title：Brain research

authors： Ziobro JM,Deshpande LS,Delorenzo RJ

更新日期：2011-01-31 00:00:00

abstract：:A Rous Sarcoma virus transformed cerebellar cell line, BC6, secretes a factor which causes clonal glial cell lines to rapidly (1 h) extend processes. The factor shows a degree of specificity since only 3 out of 10 lines which exhibit either glial or combined glial and neuronal properties respond. The active factor app...

journal_title：Brain research

authors： Beutler D,Giotta GJ

更新日期：1983-12-01 00:00:00

abstract：:After glucocorticoid stimulation, glucocorticoid receptors (GRs) are translocated to the nucleus to modulate transcription of glucocorticoid target genes. The subcellular distribution and trafficking of GR in cultured cells has been studied quite intensively using several techniques. However, the intracellular localiz...

journal_title：Brain research

authors： Sarabdjitsingh RA,Meijer OC,de Kloet ER

更新日期：2010-05-17 00:00:00

abstract：:Opioid-binding cell adhesion molecule (OBCAM) is the member of the IgLON family, a subgroup of the immunoglobulin superfamily. In the present study, the functions and dynamics of OBCAM were investigated in hippocampal neurons in vitro. Western blotting revealed that OBCAM expression was low at early stages of culture ...

journal_title：Brain research

authors： Yamada M,Hashimoto T,Hayashi N,Higuchi M,Murakami A,Nakashima T,Maekawa S,Miyata S

更新日期：2007-08-24 00:00:00

abstract：:The origin of the afferents of the thalamic anterior paraventricular and parataenial nuclei (PVA-PT) in the rat was studied with fluorescent retrograde tracing method. After iontophoretic application of Fluoro-Gold into PVA-PT, many labeled cells were found in the medial frontal cortex, ventral subiculum, claustrum, s...

journal_title：Brain research

authors： Chen S,Su HS

更新日期：1990-07-02 00:00:00

abstract：:The recently identified neuropeptide QRFP(26) is predominantly expressed in the hypothalamus and was suggested to play a role in the regulation of food intake following the observation of an acute orexigenic effect after central administration in mice. QRFP(26) exerts its effect via GPR103 and a newly identified recep...

journal_title：Brain research

authors： Kampe J,Wiedmer P,Pfluger PT,Castaneda TR,Burget L,Mondala H,Kerr J,Liaw C,Oldfield BJ,Tschöp MH,Bagnol D

更新日期：2006-11-13 00:00:00

abstract：:The taste reactivity test described in the preceding paper was used to begin determining the capacity of brain stem structures to execute and regulate ingestive behavior. Both chronic thalamic and chronic decerebrate rat preparations were examined repeatedly, and their gustatory mimetic responses compared through fram...

journal_title：Brain research

authors： Grill HJ,Norgren R

更新日期：1978-03-24 00:00:00

abstract：:Neurofilament expression in peripheral olfactory neurons of adult rats was investigated by immunoblotting and immunohistochemistry using monoclonal antibodies specific for each of the 3 neurofilament proteins. Immunoblotting analysis of olfactory epithelium extracts demonstrated the presence of only the 200 kDa (NFH) ...

journal_title：Brain research

authors： Bruch RC,Carr VM

更新日期：1991-05-31 00:00:00

abstract：:Several regulated mRNAs were detected by applying differential display to the mouse cerebellum during postnatal development. One cDNA fragment, referred to as CPD1 (GenBank U89345), was characterized and cloned. Northern blots showed maximum mRNA expression at postnatal day seven (P7). The mRNA encodes a protein of 26...

journal_title：Brain research

authors： Radrizzani M,Vilá-Ortiz G,Cafferata EG,Di Tella MC,González-Guerrico A,Perandones C,Pivetta OH,Carminatti H,Idoyaga Vargas VP,Santa-Coloma TA

更新日期：2001-07-13 00:00:00

abstract：:Enkephalin-like immunoreactive nerve fibers in the celiac ganglion of guinea pigs were characterized by a high population of large granular vesicles mixed with small clear vesicles. The immunoreactive material is confined to the large granular vesicles. The immunoreactive nerve fibers formed many axo-dendritic as well...

journal_title：Brain research

authors： Kondo H,Yui R

更新日期：1982-12-02 00:00:00

abstract：:Strychnine-sensitive, inhibitory glycine receptors have not until lately been considered to play a significant role in neurotransmission in mammalian forebrain regions. In order to investigate the role of glycine as a neurotransmitter in brain we have measured glycine induced chloride fluxes in different adult rat for...

journal_title：Brain research

authors： Engblom AC,Eriksson KS,Akerman KE

更新日期：1996-03-11 00:00:00

abstract：:We have shown that high-concentration albumin therapy is markedly neuroprotective in focal cerebral ischemia. The present study was conducted to ascertain the degree to which hemodynamic alterations are responsible for this therapeutic effect. Normothermic, physiologically regulated male Sprague-Dawley rats received a...

journal_title：Brain research

authors： Huh PW,Belayev L,Zhao W,Busto R,Saul I,Ginsberg MD

更新日期：1998-08-31 00:00:00

abstract：:This study addressed the issue of multiple parallel auditory processing systems and their relationship to the skull-recorded auditory evoked potentials (AEPs) in the unanesthetized, unrestrained rat. In the preceding paper (Brain Res., 602 (1993) 240-250) it has been shown that auditory cortex activity does not contri...

journal_title：Brain research

authors： Simpson GV,Knight RT

更新日期：1993-02-05 00:00:00

abstract：:Confocal microscopy and the Ca(2+)-sensitive fluorescent dye fluo-3 were used to study subcellular Ca2+ signals in embryonic, neonatal, and adult dorsal root ganglion (DRG) neurons in excised dorsal root ganglia. Optical images obtained from isolated whole embryonic and neonatal ganglia revealed a marked variability i...

journal_title：Brain research

authors： Utzschneider DA,Rand MN,Waxman SG,Kocsis JD

更新日期：1994-01-28 00:00:00

abstract：:Our previous work has demonstrated that 100-Hz electroacupuncture (EA) or 100-Hz transcutaneous electrical nerve stimulation (TENS) was very effective in ameliorating the morphine withdrawal syndrome in rats and humans. The mechanism was obscure. (1) Rats were made dependent on morphine by repeated morphine injections...

journal_title：Brain research

authors： Wu LZ,Cui CL,Tian JB,Ji D,Han JS

更新日期：1999-12-18 00:00:00

abstract：:Immunohistochemical expression of the doublecortin (DCX) gene product was investigated in cerebral cortices from 33 normal developing human, aged 9 gestational weeks (GW) to 29 years, and from 26 patients with various neuronal migration disorders, aged 19 GW to 34 years. DCX immunoreactivity was detected predominantly...

journal_title：Brain research

authors： Qin J,Mizuguchi M,Itoh M,Takashima S

更新日期：2000-04-28 00:00:00

abstract：:The effects of the dopamine transporter (DAT) inhibitors cocaine and GBR12909 on DAT and dopamine D(2) receptors were evaluated in the brains under awake and isoflurane-anesthetized monkeys using high-resolution positron emission tomography (PET) in combination with microdialysis. The striatal DAT availability and dop...

journal_title：Brain research

authors： Tsukada H,Nishiyama S,Kakiuchi T,Ohba H,Sato K,Harada N,Nakanishi S

更新日期：1999-12-04 00:00:00

abstract：:The interposed nuclei (IN) of the intermediate cerebellum are critical components of the circuits that control associative learning of eyeblinks and other defensive reflexes in mammals. The IN, which represent the sole output of the intermediate cerebellum, receive massive GABAergic input from Purkinje cells of the ce...

journal_title：Brain research

authors： Parker KL,Zbarska S,Carrel AJ,Bracha V

更新日期：2009-10-06 00:00:00

abstract：:Neurotensin-producing perikarya and fibers have been identified in the ventral tegmental area of the rat, and recent microinjection studies indicate that neurotensin may function in the ventral tegmental area to regulate body temperature. In this study, the hypothermic response produced by intraventral tegmental injec...

journal_title：Brain research

authors： Kalivas PW,Nemeroff CB,Miller JS,Prange AJ Jr

更新日期：1985-02-11 00:00:00

abstract：:This study examines the preventive and therapeutic effects of curcumin on brain edema after hypoxic-ischemic brain damage (HIBD) in a rat model. Male Sprague-Dawley rats were divided into four groups: a sham group (SH), a hypoxic-ischemic group (HI) without drug treatment, a hypoxic-ischemic group (CU) with curcumin i...

journal_title：Brain research

authors： Yu L,Yi J,Ye G,Zheng Y,Song Z,Yang Y,Song Y,Wang Z,Bao Q

更新日期：2012-09-26 00:00:00

abstract：:Intravenous administration of lipopolysaccharide (LPS) (0.9 mg/kg) has been shown to induce ischemic tolerance in spontaneously hypertensive rats (SHR). TNF-alpha is believed to play a crucial role in preconditioning as its inhibition with TNF-alpha-binding protein abolished tolerance. Our recent studies (Liu et al., ...

journal_title：Brain research

authors： Zimmermann C,Ginis I,Furuya K,Klimanis D,Ruetzler C,Spatz M,Hallenbeck JM

更新日期：2001-03-23 00:00:00

abstract：:Surgical tissue samples of the human dentate gyrus were immunostained for glutamate decarboxylase (GAD), the gamma-aminobutyric acid (GABA)-synthesizing enzyme, and studied by both light and electron microscopy. Immunoreactive neurons and terminals displayed similar morphological characteristics as known from studies ...

journal_title：Brain research

authors： Schlander M,Thomalske G,Frotscher M

更新日期：1987-01-13 00:00:00

abstract：:Dissociated 4-day (stage 23) chick embryo lumbar cord cells were cultured at low or high cell densities for 1 or 5 days in the presence or absence of added spinal neuronotrophic factor (supplied as RN22 Schwannoma conditioned medium, RCM). In low density, 1-day cultures neuronal survival was dependent on added RCM whe...

journal_title：Brain research

authors： Manthorpe M,Luyten W,Longo FM,Varon S

更新日期：1983-05-09 00:00:00

abstract：:Antisense oligodeoxynucleotides (ODNs) are used for the selective inhibition of gene expression. Antisense ODNs are promising tools for the investigation of physiological implications of proteins in the central nervous system of rodents in vivo. We have previously demonstrated that a phosphorothioate antisense ODN to ...

journal_title：Brain research

authors： Karle J,Witt MR,Nielsen M

更新日期：1997-08-08 00:00:00

abstract：:Visual search is characterized as efficient (RT independent of distractor number) or inefficient (RT increasing with distractor number). Our goal was to determine if any brain regions are differentially activated by the attentional demands of these two search modes. We used fMRI to examine activation patterns during s...

journal_title：Brain research

authors： Kim KK,Eliassen JC,Lee SK,Kang E

更新日期：2012-09-26 00:00:00

abstract：:Chronic neuropathic pain has demonstrated that coexisting psychiatric disorders are associated with disability and poorer treatment outcomes. Hyperpolarization-activated cyclic nucleotide-gated (HCN, Ih) channels play a major role in pain via hyperexcitability and facilitation of ectopic firing in neurons. Neuronal hy...

journal_title：Brain research

authors： Yang L,Liu X,Yao K,Sun Y,Jiang F,Yan H,Mao P,Fan S,Wei X,Liu Y,Yuan W,Zhang S

更新日期：2019-08-15 00:00:00

abstract：:The possible interference of nitric oxide (NO) in glucose metabolism was studied in activated astrocytes. Lipopolysaccharide (LPS) treatment triggered a NO-mediated increase in glucose consumption and lactate production, suggesting an enhanced rate of glycolysis. Active glycogen synthesis was also observed after LPS t...

journal_title：Brain research

authors： Almeida A,Cidad P,Bolaños JP

更新日期：2002-07-26 00:00:00

abstract：:The Timm and selenium staining techniques, based on silver amplification of endogenous zinc, produce an electron-dense precipitate in boutons. The staining characteristics of the two methods were compared by examining two allocortical regions, prepiriform cortex and entorhinal cortex, in the brain of the European hedg...

journal_title：Brain research

authors： Schwerdtfeger WK,Danscher G,Geiger H

更新日期：1985-11-25 00:00:00

abstract：:Subtypes of muscarinic receptors were characterized in the frontal cortices of control and Alzheimer brains, with labelled quinuclidinyl benzilate [3H]QNB and the unlabelled muscarinic antagonists pirenzepine, AF-DX 116, hexahydro-sila-diphenidol (HHSiD), para-fluoro-hexahydro-sila-diphenidol (p-F-HHSiD) and himbacine...

journal_title：Brain research

authors： Svensson AL,Alafuzoff I,Nordberg A

更新日期：1992-11-20 00:00:00