Effect of central administration of QRFP(26) peptide on energy balance and characterization of a second QRFP receptor in rat.

abstract：:Rats selectively bred for high or low levels of emotionality represent an important and powerful tool to investigate the role of genetic variables in the occurrence of different anxiety disorders. In the present study, albino rats were selectively bred for differences in defensive freezing behavior in response to cont...

journal_title：Brain research

authors： de Castro Gomes V,Landeira-Fernandez J

更新日期：2008-10-03 00:00:00

abstract：:Intracellular Neurobiotin-injections were used to label functionally identified neurons in the rostro-dorsomedial part of the trigeminal oral nucleus (Vo.r) in the cat. The labeled Vo.r neurons with the mechanoreceptive field in oral tissues innervated bilaterally either jaw-opening motoneurons or jaw-closing motoneur...

journal_title：Brain research

authors： Yoshida A,Yamamoto M,Moritani M,Fukami H,Bae YC,Chang Z,Sugiyo S,Takemura M,Park KP,Shigenaga Y

更新日期：2005-03-02 00:00:00

abstract：:Our previous studies have indicated that oxygen radicals, produced during reoxygenation following short-term arterial hypoxia, lead to sustained suppression of cerebral arteriolar responses to N-methyl-D-aspartate (NMDA). However, whether arteriolar dilator responses to NMDA are reduced during arterial hypoxia has nev...

journal_title：Brain research

authors： Bari F,Thore CR,Louis TM,Busija DW

更新日期：1998-01-12 00:00:00

abstract：:Different groups of rats received three injections of either D-amphetamine (2.5 micrograms/0.5 microliters/side) or saline into the ventral tegmental area (VTA), one injection every third day. Two weeks following the last injection, dopamine (DA) neurotransmission in the nucleus accumbens (N. Acc.) was assessed with i...

journal_title：Brain research

authors： Vezina P

更新日期：1993-03-12 00:00:00

abstract：:Gabapentin, a drug useful in several neurological and psychiatric disorders, decreased K(+) (15 mM)-induced [Ca(2+)](i) increase in Fura-PE3-loaded rat neocortical synaptosomes (IC(50)=9.7 microM; submaximal inhibition of 28.6%). This effect may indicate a selective modulation of presynaptic Ca(2+) influx in response ...

journal_title：Brain research

authors： Meder WP,Dooley DJ

更新日期：2000-09-01 00:00:00

abstract：:To evaluate the role of the amygdala in pain modulation and opioid-mediated antinociception, a recombinant, replication-defective herpes virus carrying the human preproenkephalin cDNA was injected bilaterally into the rat amygdala. Four days after gene delivery nociceptive behavior was assessed by the formalin test. R...

journal_title：Brain research

authors： Kang W,Wilson MA,Bender MA,Glorioso JC,Wilson SP

更新日期：1998-05-04 00:00:00

abstract：:Microtubule organization in type I hair cells has been investigated during the synaptogenesis of vestibular receptors in mammals. The different steps in the maturation of the synapse between the hair cell and the nerve chalice were: a slight symmetrical membrane densification; the appearance of synaptic bodies alongsi...

journal_title：Brain research

authors： Favre D,Dememes D,Sans A

更新日期：1986-02-01 00:00:00

abstract：:Erythropoietin (EPO), a hematopoietic hormonal cytokine induced in response to hypoxia, has neuroprotective effects. EPO receptor (EPOR) is expressed in microglia, resident immune cells in the brain. However, the effect of EPO on microglial activation is not clear. In the present study, we demonstrated that the EPOR i...

journal_title：Brain research

authors： Tamura T,Aoyama M,Ukai S,Kakita H,Sobue K,Asai K

更新日期：2017-05-01 00:00:00

abstract：:Alterations in protein phosphorylation may be important in the pathogenesis of Alzheimer's disease and recent observations suggest that a subset of protein kinase pathways may be selectively altered. Calcium/calmodulin-dependent protein kinase II CaM kinase II) is the most abundant protein kinase in the brain and is b...

journal_title：Brain research

authors： Simonian NA,Elvhage T,Czernik AJ,Greengard P,Hyman BT

更新日期：1994-09-19 00:00:00

abstract：:Cytochrome P45011B1 (11 beta-hydroxylase) was detected in the brain of male rats by in situ hybridization methods. Normal Sprague-Dawley rats were compared to the transgenic strain TGR(mRen2)27, characterized by the expression of the murine Ren-2d renin gene and the development of severe hypertension. Specific ribopro...

journal_title：Brain research

authors： Erdmann B,Gerst H,Lippoldt A,Bülow H,Ganten D,Fuxe K,Bernhardt R

更新日期：1996-09-09 00:00:00

abstract：:Amnestic type mild cognitive impairment (aMCI) refers to a transitional stage between normal aging and Alzheimer's disease (AD). Whilst posterior cingulate cortex (PCC) is believed to have a key role in a default network and be involved in the pathophysiology of AD, few studies have investigated whole-brain functional...

journal_title：Brain research

authors： Bai F,Watson DR,Yu H,Shi Y,Yuan Y,Zhang Z

更新日期：2009-12-11 00:00:00

abstract：:Kindling of the ventral tegmental area (VTA), a major source of the mesolimbic dopamine pathway, was examined in rats. We applied two quantitative measurements of dopamine sensitivity before and 2 weeks after VTA kindling (20 times electrical stimulations (100 microA at 1 min intervals) delivered once per day for 14 c...

journal_title：Brain research

authors： Watanabe T,Morimoto K,Nakamura M,Hirao T,Ninomiya T,Ando N,Suwaki H

更新日期：2004-04-02 00:00:00

abstract：:The immunocytological study of LH-RH producing neurons was carried out on 3 newborns and 14 fetuses (from 10 to 36 weeks of age). Perikarya and fibers which were immunoreactive to anti-LH-RH IS were revealed by IF or IE in all the hypothalamus beginning with the 13th week. Important variations in neurons staining may ...

journal_title：Brain research

authors： Bugnon C,Bloch B,Fellmann D

更新日期：1977-06-10 00:00:00

abstract：:Intracellular recordings were made from neurons in the isolated myenteric plexus of the guinea-pig ileum. Methionine- and leucine-enkephalin were applied to the neurons either by adding them to the perfusing solution in known concentrations or be ejecting them by microiontophoresis. When applied in the perfusion solut...

journal_title：Brain research

authors： North RA,Katayama Y,Williams JT

更新日期：1979-04-06 00:00:00

abstract：:Wayfinding is a complex cognitive function involving different types of information, such as knowledge about landmarks and direction information. This variety of processes suggest that multiple neural mechanisms are involved, e.g., the hippocampal system, the posterior parietal and temporal cortical areas. Although pa...

journal_title：Brain research

authors： van Asselen M,Kessels RP,Kappelle LJ,Neggers SF,Frijns CJ,Postma A

更新日期：2006-01-05 00:00:00

abstract：:This work describes the presence of glucocorticoid binding sites in human temporal cortex obtained following partial lobectomy in two epileptic patients. Using [3H]dexamethasone as radioligand and cold cortisol or RU 28362 as competitor we found an apparent Kd of approximately 2.8 nM with a Bmax of approximately 34 fm...

journal_title：Brain research

authors： Sarrieau A,Dussaillant M,Sapolsky RM,Aitken DH,Olivier A,Lal S,Rostène WH,Quirion R,Meaney MJ

更新日期：1988-02-23 00:00:00

abstract：:Intracisternal administration of aluminum maltolate to rabbits produces a marked argyrophilic neurofibrillary degeneration (NFD) which is also immunoreactive for both phosphorylated and non-phosphorylated microtubule associated protein tau. Using tissue fixation in PBF, the monoclonal antibodies Tau-2 and AT8 stain th...

journal_title：Brain research

authors： Savory J,Huang Y,Herman MM,Reyes MR,Wills MR

更新日期：1995-01-16 00:00:00

abstract：:In the present study, we used an immunocytochemical technique at the electron microscopic level to determine if there are changes in the glutamate and GABA neurotransmitter content of the hippocampus of genetic absence epilepsy rats from Strasbourg (GAERS). We also investigated if there was mossy fiber reorganization....

journal_title：Brain research

authors： Sirvanci S,Meshul CK,Onat F,San T

更新日期：2003-10-24 00:00:00

abstract：:The role of the lateral parabrachial area (lPB) in the acquisition of a delayed taste aversion learning task (TAL) was examined by delivering the peripherally acting aversive compound, methylscopolamine (MSP), through two different routes, intraperitoneal and intraventricular. Consistent with previous anatomical, beha...

journal_title：Brain research

authors： Cubero I,Puerto A

更新日期：2000-07-14 00:00:00

abstract：:Aluminum (Al) concentrations of the rat frontal cortex, parietal cortex, and hippocampus were measured by atomic absorption spectroscopy 16 days after a unilateral intracerebroventricular injection of Na gluconate, Al gluconate, or the cholinotoxin AF64A. A fourth group of rats were injected with AF64A 6 days before i...

journal_title：Brain research

authors： Szerdahelyi P,Kása P

更新日期：1988-03-22 00:00:00

abstract：:Previous results indicate that the dopaminergic system in the anterior medial zona incerta (ZI) exerts a stimulatory effect on LH release. In this report changes in dopamine (DA) turnover in the ZI, preoptic area (POA) and arcuate/median eminence area (ARC/ME) (as assessed by the rate of decline in DA concentration af...

journal_title：Brain research

authors： MacKenzie FJ,James MD,Wilson CA

更新日期：1988-03-15 00:00:00

abstract：:The aim of this study was to identify the medullary vagal nuclei involved in the different phases of swallowing activated physiologically in a species with an esophagus similar to human. In decerebrate cats, the pharyngeal (0.5-1.0 ml water in pharynx (N=6)) or esophageal (1-3 ml air in esophagus (N=5)) phases of swal...

journal_title：Brain research

authors： Lang IM,Dean C,Medda BK,Aslam M,Shaker R

更新日期：2004-07-16 00:00:00

abstract：:Histaminergic fibers in the mesencephalic nucleus of the trigeminal nerve of Long-Evans rats were examined by light and electron microscopy after peroxidase-antiperoxidase immunocytochemical staining for histidine decarboxylase (HDC) as a marker. By light microscopy, neurons in the mesencephalic nucleus of the trigemi...

journal_title：Brain research

authors： Inagaki N,Yamatodani A,Shinoda K,Shiotani Y,Tohyama M,Watanabe T,Wada H

更新日期：1987-08-25 00:00:00

abstract：:Prestin has been identified as a motor protein responsible for outer hair cell (OHC) electromotility. Previous experiments revealed that OHC electromotility and its associated nonlinear capacitance resided in the OHC lateral wall and was not detected at the apical cuticular plate and basal region. In this experiment, ...

journal_title：Brain research

authors： Yu N,Zhu ML,Zhao HB

更新日期：2006-06-20 00:00:00

abstract：:The protective effect of mild hypothermia was studied in rodent models of both permanent and transient focal cerebral ischemia. In Expt. 1, Wistar rats were exposed to 6 h permanent ischemia by bilateral occlusion of both common carotid arteries and right middle cerebral artery. In Expt. 2, animals were exposed to 3 h...

journal_title：Brain research

authors： Xue D,Huang ZG,Smith KE,Buchan AM

更新日期：1992-07-31 00:00:00

abstract：:Freezing and escape responses induced by gradual increases in the intensity of the electrical current applied to dorsal regions of the periaqueductal gray (dPAG) cause a distinct pattern of Fos distribution in the brain. From these studies, it has been suggested that a pathway involving the dPAG itself, dorsomedial hy...

journal_title：Brain research

authors： Ferreira-Netto C,Borelli KG,Brandão ML

更新日期：2005-01-21 00:00:00

abstract：:The localization of human hand primary motor area (M1) has been the object of several studies during the last decades. EEG source analysis, functional magnetic resonance imaging (fMRI) and focal transcranial magnetic stimulation (TMS) are non-invasive methods for localizing M1 with good accuracy compared to direct ele...

journal_title：Brain research

authors： Inuggi A,Filippi M,Chieffo R,Agosta F,Rocca MA,González-Rosa JJ,Cursi M,Comi G,Leocani L

更新日期：2010-01-13 00:00:00

abstract：:It is well documented that VMAT2 protects nigrostriatal DA neurons against MPP(+) by sequestering it inside vesicles away from its mitochondrial site of neurotoxic action. However, the implication of the VMAT2 in the mechanism of action exerted by 6-OHDA has received little attention. Therefore, the aim of the present...

journal_title：Brain research

authors： Cleren C,Naudin B,Costentin J

更新日期：2003-11-07 00:00:00

abstract：:Synaptosomes prepared from fresh human cerebral cortex were shown to be morphologically similar to those from other species. On incubation, they took up oxygen at a high and linear rate and accumulated potassium against a concentration gradient. In response to depolarization by raised extracellular K+ or addition of v...

journal_title：Brain research

authors： Dodd P,Hardy JA,Oakley AE,Strong AJ

更新日期：1981-11-16 00:00:00

abstract：:Transient ischemic attack (TIA) has received only little attention in the experimental research field. Recently, we introduced a TIA model for mice, and here we set similar principles for simulating this human condition in Wistar rats. In the model: 1) transient nature of the event is ensured, and 2) 24h after the eve...

journal_title：Brain research

authors： Durukan Tolvanen A,Tatlisumak E,Pedrono E,Abo-Ramadan U,Tatlisumak T

更新日期：2017-05-15 00:00:00