Renal proximal tubule cell cultures for studying drug-induced nephrotoxicity and modulation of phenotype expression by medium components.

abstract：BACKGROUND:Intima-Media-Thickness of the carotid artery wall (cIMT) is a strong predictor of cardiovascular (CV) disease. The aim of this study was to investigate the significance of cIMT as an independent prognostic factor for CV morbidity and mortality in patients with chronic kidney disease (CKD) and diabetes mellit...

journal_title：Renal failure

authors： Roumeliotis A,Roumeliotis S,Panagoutsos S,Theodoridis M,Argyriou C,Tavridou A,Georgiadis GS

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Augmentation index (AIx) and pulse wave velocity (PWV) are early markers of atherosclerotic vascular changes and also have been shown to be predictive of cardiovascular disease and total mortality. The aim of our study was to evaluate the relationship between PWV and AIx-HR75, which is the corrected form of ...

journal_title：Renal failure

authors： Celik G,Demirci MS,Tumuklu M,Ascı G,Sipahi S,Toz H,Bascı A,Ok E

更新日期：2011-01-01 00:00:00

abstract：:Approximately one-third of all dialysis patients have mild to moderate malnutrition, while 6-8% have severe malnutrition, which is associated with increased morbidity and mortality rates and numerous pre-existing factors directly correlated with, or existing prior to, replacement hemodialysis. However, moderate to sev...

journal_title：Renal failure

authors： Lacquaniti A,Bolignano D,Campo S,Perrone C,Donato V,Fazio MR,Buemi A,Sturiale A,Buemi M

更新日期：2009-01-01 00:00:00

abstract：UNLABELLED:Contrast-induced nephropathy (CIN) is the third leading cause of acute kidney injury (AKI) in hospitalized patients. Diabetes mellitus remains a consistent independent predictor of contrast nephropathy. AIM:To determine frequency and predictors of contrast-induced nephropathy after cardiac catheterization i...

journal_title：Renal failure

authors： Sany D,Refaat H,Elshahawy Y,Mohab A,Ezzat H

更新日期：2014-03-01 00:00:00

abstract：:The aim of this study was to assess the effect of nifedipine and piracetam alone or in combination in the protection of renal function and morphology after cyclosporin A (CyA) administration. Thirty healthy mongrel dogs with a mean body weight of 15 kg were sacrificed. Six animals (group C) were given CyA 20 mg/kg bod...

journal_title：Renal failure

authors： Grekas D,Alivanis P,Kalekou H,Papayianni K,Karamouzis M,Tourkantonis A

更新日期：1992-01-01 00:00:00

abstract：:A 68-year-old male presented with acute myeloid leukemia, renal failure, hypokalemia, and enlarged kidneys on renal ultrasound. Renal biopsy revealed massive leukemic infiltration of the kidney. After systemic chemotherapy, the patient developed tumor lysis syndrome followed by a phase of proximal tubule dysfunction p...

journal_title：Renal failure

authors： Rüger W,Kruip MJ,Betjes MG

更新日期：2009-01-01 00:00:00

abstract：:Toxoplasma gondii is one of the important opportunistic pathogen among solid-organ transplant recipients and hemodialysis patients (HD). This study was aimed to detect toxoplasmosis among 50 renal transplant recipients (RTR), 135 HD and 120 healthy individuals in two cities (Kashan and Qom) that located in the center ...

journal_title：Renal failure

authors： Rasti S,Hassanzadeh M,Soliemani A,Hooshyar H,Mousavi SG,Nikoueinejad H,Abdoli A

更新日期：2016-07-01 00:00:00

abstract：:We present a case of an extremely rare form of Ewing sarcoma--primary disseminated, with fulminating course, severe hypercalcemia, extensive calcium deposition in parenchymatous organs, including kidneys, and acute renal failure as a clinical consequence. Correction of hypercalcemia was followed by prompt restoration ...

journal_title：Renal failure

authors： Lozance LA,Zafirovska KG,Bogdanovska SV,Zafirovski GJ

更新日期：1994-01-01 00:00:00

abstract：:We report a case of rapidly progressive diabetic nephropathy, from little diabetic change on renal biopsy to severe, nodular, diabetic nephrosclerosis over 32 months. The patient was taking an angiotensin converting enzyme inhibitor and had a mean arterial pressure of 95 mm Hg over this time period. Her dietary protei...

journal_title：Renal failure

authors： Dillon JJ,Sedmak DD,Cosio FG

更新日期：1997-11-01 00:00:00

abstract：:During times of war or natural disasters, rhabdomyolysis leading to acute kidney injury (AKI) can assume epidemic proportions. Fasudil attenuates ischemia/reperfusion-induced AKI. We investigated the therapeutic effect of an early application of fasudil on AKI induced by rhabdomyolysis and explored the potential mecha...

journal_title：Renal failure

authors： Wang YD,Zhang L,Cai GY,Zhang XG,Lv Y,Hong Q,Shi SZ,Yin Z,Liu XF,Chen XM

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Renal artery stenosis is an important cause of hypertension and renal failure. When present in a solitary kidney, it is associated with extremely high morbidity and mortality. Although guidelines suggest an aggressive approach by revascularization in these cases, available evidence is too weak and contradict...

journal_title：Renal failure

authors： Feldman L,Beberashvili I,Averbukh Z,Weissgarten J

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Renal cystic disorders (RCD) constitute an important and leading cause of end-stage renal disease (ESRD) in children. It can be acquired or inherited; isolated or associated with extrarenal manifestations. The precise diagnosis represents a difficult clinical challenge. METHODS:The aim of this study was to ...

journal_title：Renal failure

authors： Soliman NA,Nabhan MM,Bazaraa HM,Badr AM,Shaheen M

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:There are few reports on the safety and efficacy of long-term treatment with statins in patients with chronic renal disease and hyperlipidemia. We evaluated these subjects treated with fluvastatin. METHODS:After a 4-week run-in period, a total of 80 patients with diabetic nephropathy or chronic glomerulonep...

journal_title：Renal failure

authors： Yasuda G,Kuji T,Hasegawa K,Ogawa N,Shimura G,Ando D,Umemura S

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Diabetic nephropathy (DN) is a leading cause of diabetes-related morbidity and mortality. The aim of this study was to evaluate the relationship of AGT M235T and apoprotein E (APO E) gene polymorphism with DN in Turkish patients of Type 2 diabetes, and to compare genotype and allele distributions among DN pa...

journal_title：Renal failure

authors： Reis KA,Ebinç FA,Koç E,Demirci H,Erten Y,Güz G,Derici UB,Bali M,Söylemezoğlu O,Arınsoy T,Sindel S

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND AIM:There is an increased mortality risk in long-term hemodialysis patients of renal failure due to the chronic inflammation. The relationship between the chronic renal failure (CRF) and the role of familial genetic markers remains incompletely understood. In the current study, it was aimed to find out t...

journal_title：Renal failure

authors： Ozdemir O,Kayatas M,Cetinkaya S,Yildirim ME,Silan F,Kurtulgan HK,Koksal B,Urfali M,Candan F

更新日期：2015-03-01 00:00:00

abstract：:The present work examines the role of uremia and the effect of dialysis treatment on red blood cells (RBCs) membrane properties of hemodialysis patients. The results showed that, the uremic patients had a lower values of erythrocyte deformability than that of healthy control subject. The median osmotic fragility (MOF)...

journal_title：Renal failure

authors： Ibrahim FF,Ghannam MM,Ali FM

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:An elevated serum C-reactive protein (CRP) is strongly associated with morbidity and mortality in dialysis patients. However, the significance of high CRP levels in pre-dialysis patients has not been studied extensively. The aim of this study was to determine the prevalence of elevated serum CRP in pre-dialy...

journal_title：Renal failure

authors： Razeghi E,Parkhideh S,Ahmadi F,Khashayar P

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:Study the possible excretion of vitamin A in urine of critically ill patients complicated with acute renal failure. PATIENTS AND METHODS:Nine Intensive Care Unit patients, age 71.2 +/- 15.7 (mean +/- SD) with acute renal failure were studied. Urinary retinol, creatinine, protein, albumin, and serum creatinin...

journal_title：Renal failure

authors： Gavrilov V,Weksler N,Ahmed A,Gorodischer R

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVES:In Taiwan, the widespread use of organophosphates (OPs) in agricultural and household environments results in numerous OP poisoning. To better understand the clinical significance of associated parameters on respiratory failure and patient outcome, we evaluate patients admitted to the Nephrology ward in our ...

journal_title：Renal failure

authors： Lin CL,Yang CT,Pan KY,Huang CC

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Arteriovenous fistulae (AVFs) may remain patent after kidney transplantation (KTx), contributing to maladaptive cardiac remodeling. The flow in AVFs is associated with the diameter of its vessels and thus with the AVF location. The main objective of this study is to assess the influence of AVF location and i...

journal_title：Renal failure

authors： Letachowicz K,Bardowska K,Królicki T,Kamińska D,Banasik M,Zajdel K,Mazanowska O,Madziarska K,Janczak D,Krajewska M

更新日期：2021-12-01 00:00:00

abstract：:The role of the kidney in the control of blood pressure has been convincingly demonstrated by several studies. Recent evidence has suggested that subtle acquired tubulointerstitial injury may cause a defect in sodium excretion function, thus leading to salt-sensitive hypertension. There are no reports, however, examin...

journal_title：Renal failure

authors： de Magalhães Sartim R,Fantinato Menegon L,de Almeida AR,Rocha Gontijo JA,Aline Boer P

更新日期：2006-01-01 00:00:00

abstract：BACKGROUNDS/AIMS:Renal ischemia-reperfusion (IR) induces organ damage in remote organs. The aim of this study was to assess the role of leukocytes in the induction of liver damage after renal IR injury. METHODS:Inbred mice were subjected to either sham operation or bilateral renal IR injury (60 min ischemia followed b...

journal_title：Renal failure

authors： Khastar H,Kadkhodaee M,Sadeghipour HR,Seifi B,Hadjati J,Delavari F,Soleimani M

更新日期：2011-01-01 00:00:00

abstract：:In chronic renal failure (CRF), phosphate (Pi) retention may lead to secondary hyperparathyroidism and progression to end-stage renal disease (ESRD). Dietary phosphorus restriction or phosphate binders can slow progression in experimental CRF. Conversely, diets high in phosphorus can accelerate the progression toward ...

journal_title：Renal failure

authors： Loghman-Adham M,Motock GT

更新日期：1996-11-01 00:00:00

abstract：UNLABELLED:Cytomegalovirus (CMV) disease is an important complication and an independent risk factor for acute rejection and recipient morbidity-mortality. The aim of this study was to review the results of CMV disease in renal transplant recipients. METHOD:We have retrospectively analyzed CMV disease in 120 renal tra...

journal_title：Renal failure

authors： Cavdar C,Celtik A,Saglam F,Sifil A,Atila K,Celik A,Tosun P,Olmuscelik O,Bora S,Gulay H,Camsari T

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Besides possible bleeding complications a further problem in anticoagulation during continuous renal replacement therapy (CRRT) is the development of heparin-induced thrombocytopenia type II (HIT II) where further anticoagulation with heparin is contraindicated. The application of continuous hirudin as alter...

journal_title：Renal failure

authors： Hein OV,von Heymann C,Diehl T,Ziemer S,Ronco C,Morgera S,Siebert G,Kox WJ,Neumayer HH,Spies C

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Previous studies have shown that MPO -463G > A (rs2333227) might be associated with chronic kidney disease (CKD) susceptibility, but sample sizes of those studies are relatively small. Hence, we decided to perform a meta-analysis to evaluate the association. Methods/main results: Two investigators ...

journal_title：Renal failure

authors： Qin J,Xing J,Li W,Zhang K,Wu Z

更新日期：2018-11-01 00:00:00

abstract：:The proximal convoluted tubule (PCT) is the major target for injury in gentamicin nephrotoxicity but the necrosis is often patchy and focal. The PCT is structurally, functionally, and metabolically heterogeneous, and the possibility of differential vulnerability to gentamicin-induced necrosis based on this heterogenei...

journal_title：Renal failure

authors： Shanley PF,Burke TJ

更新日期：1990-01-01 00:00:00

abstract：:In vascular smooth muscle, calcium overload is a highly pathogenic event, which increases with advancing age. An increase in the calcium content of arterial wall may be produced in rats by treatment with vitamin D3. The aim of this study was to evaluate the renal clearance of sulfanilamide (a model organic anion, pref...

journal_title：Renal failure

authors： Quaglia NB,Brandoni A,Ferri A,Torres AM

更新日期：2003-05-01 00:00:00

abstract：:Envenomations by venomous lizards are rare. Monitor lizard bite-induced acute kidney injury (AKI) is a previously unreported complication in humans. A 55-year-old female was bitten on her right leg during farming activity by a monitor lizard (Varanus bengalensis). The patient experienced severe local pain and bleeding...

journal_title：Renal failure

authors： Vikrant S,Verma BS

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Peritonitis, the most important limitation of peritoneal dialysis (PD), could be detected by biomarkers in dialysate effluent, representing a noninvasive method to indirectly assess the peritoneum status. The aim of our study was to test high mobility group box 1 (HMGB1) in PD patients, evaluating its role a...

journal_title：Renal failure

authors： Chimenz R,Lacquaniti A,Colavita L,Chirico V,Fede C,Buemi M,Fede C

更新日期：2016-10-01 00:00:00