Fasudil ameliorates rhabdomyolysis-induced acute kidney injury via inhibition of apoptosis.

abstract：:The Latin American Society of Nephrology and Arterial Hypertension's Dialysis and Transplant Registry was chartered in 1991. It collects information on ESRD and its treatment in 20 countries of the region. The prevalence of patients on renal replacement therapy (RRT) increased from 129 pmp in 1992 to 447 pmp in 2004; ...

journal_title：Renal failure

authors： Cusumano A,Garcia-Garcia G,Di Gioia C,Hermida O,Lavorato C,Carreño CA,Torrico MP,Batista PB,Romão JE,Badal HP,Miranda SE,Gomez R,Calderon MC,Sanchez SH,Lopez MA,Moscoso J,Merino RL,Polo JV,Lopez A,Romero NJ,Garcia

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Despite the effectiveness of intravenous calcitriol in suppressing parathyroid hormone secretion in patients with uremic hyperparathyroidism, 50% of the patients remain refractory to this treatment. There are conflicting reports regarding the factors that can predict the response to treatment. Technetium-99m...

journal_title：Renal failure

authors： Owda AK,Mousa D,Abdallah AH,Hawas FA,Al-Harbi W,Fedail H,At-Shoail G,Al-Sulaiman MH,Al-Khader AA

更新日期：2002-03-01 00:00:00

abstract：:Acetaminophen (APAP), also known as paracetamol, is the commonest cause of toxic ingestion in the world. Because overdose of APAP has life-threatening effects on kidney, treatment of APAP-induced nephrotoxicity has life-saving importance. Aim of the study was to evaluate the efficacy of medical ozone therapy in experi...

journal_title：Renal failure

authors： Demirbag S,Uysal B,Guven A,Cayci T,Ozler M,Ozcan A,Kaldirim U,Surer I,Korkmaz A

更新日期：2010-05-01 00:00:00

abstract：:Cystatin C is considered an indicator of acute renal failure and also a risk factor of cardiovascular disease. This study was undertaken to examine the relationship of serum cystatin C with C-reactive protein (CRP), lipids, and lipid-related compounds in patients on hemodialysis (HD). Cystatin C, CRP, total cholestero...

journal_title：Renal failure

authors： Samouilidou EC,Grapsa E

更新日期：2008-01-01 00:00:00

abstract：:Kidney transplant recipients have increased risk of cancers when compared with the general population. Hepatocellular carcinoma (HCC) is extremely important in Asia where hepatitis B virus (HBV) infection is endemic. The aim is to study the epidemiological and clinical aspects of all de novo HCC in our kidney transpla...

journal_title：Renal failure

authors： Cheung CY,Lam MF,Chow KM,Lee W,Cheng YL,Yuen SK,Wong PN,Mo KL,Leung KT,Wong SH,Ho YW,Chau KF

更新日期：2014-07-01 00:00:00

abstract：:Aldosterone is reported to promote fibrosis of multiple organs. Recent studies showed that Na+-H+ exchanger isoform 1 (NHE1) was involved in mineralocorticoid-induced tissue fibrosis. The present study examined the role of NHE1 in aldosterone-induced glomerulosclerosis in rats. SD male rats were subjected to 5/6 nephr...

journal_title：Renal failure

authors： Zhang M,Chen J,Liu S,You L,Lin S,Gu Y

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The renin-angiotensin system (RAS) has significant influences on heart and renal disease progression. Angiotensin converting enzyme (ACE) and angiotensin converting enzyme II (ACE2) are major peptidases of RAS components and play counteracting functions through angiotensin II (Ang II)/ATIR and angiotensin-(1...

journal_title：Renal failure

authors： Yang CW,Lu LC,Chang CC,Cho CC,Hsieh WY,Tsai CH,Lin YC,Lin CS

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:The quality of life in patients undergoing hemodialysis is significantly disturbed. There are data that hemodiafiltration (HDF) may be more effective than conventional hemodialysis in the removal of uremic toxins and may reduce frequency and severity of intradialytic and postdialysis adverse symptoms in pati...

journal_title：Renal failure

authors： Knezevic MZ,Djordjevic VV,Radovanovic-Velickovic RM,Stankovic JJ,Cvetkovic TP,Djordjevic VM

更新日期：2012-01-01 00:00:00

abstract：:Studies were performed in oliguric and nonoliguric forms of uranyl acetate (UA)-induced and ischemic acute renal failure (ARF) to examine whether a reduction in GFR is correlated with glomerular morphologic alterations. UA-induced nonoliguric and oliguric ARF were induced in rabbits by i.v. injections of 0.9 and 2 mg/...

journal_title：Renal failure

authors： Kato A,Hishida A,Kobayashi S,Honda N

更新日期：1993-01-01 00:00:00

abstract：:The necessary exposure of blood to biomembranes during hemodialysis has been viewed by many as an immunogenic challenge leading to an acute phase response. In this study we examined the relationship between hemodialysis-induced immune activation and intradialytic hypotension, using the acute phase reactant serum C-rea...

journal_title：Renal failure

authors： Tomita M,Malhotra D,Dheenan S,Shapiro JI,Henrich WL,Santoro TJ

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Interleukin 17 (IL-17) plays an important role in the pathogenesis of autoimmune diseases and might be associated with IgA nephropathy (IgAN). This study aimed to investigate the effect of IL-17 on autoimmune pathogenesis in IgA nephropathy. METHODS:DAKIKI cells were cultured and stimulated with IL-17 to pe...

journal_title：Renal failure

authors： Lin JR,Wen J,Zhang H,Wang L,Gou FF,Yang M,Fan JM

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Hemodialysis (HD) patients often experience cardiovascular events, that might be related to altered calcium-phosphate metabolism, dyslipidemia, and chronic inflammation in addition to hypertension. Sevelamer, a non-calcium-containing phosphate binder, may improve the lipid profile of HD patients. However, th...

journal_title：Renal failure

authors： Yamada K,Fujimoto S,Tokura T,Fukudome K,Ochiai H,Komatsu H,Sato Y,Hara S,Eto T

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Spontaneous crescentic glomerulonephritis (SCG)/Kj mice are a candidate for suitable animal model of human pauci-immune crescentic glomerulonephritis (GN). In the present study, we used renal biopsy technique and analyzed time sequence correlations among crescent formation and glomerular neutrophil infiltrat...

journal_title：Renal failure

authors： Miyazawa S,Saiga K,Nemoto K,Mae T,Hotta O

更新日期：2002-09-01 00:00:00

abstract：:Increased vascular calcification and oxidative stress are considered as extra renal risk factors at the pathogenesis cardiovascular events in chronic kidney disease (CKD). We investigated matrix Gla protein (MGP) (T-138C, Glu60X, Thr83Ala) and Klotho (Cys370Ser) gene polymorphisms, serum MGP levels, and oxidative stre...

journal_title：Renal failure

authors： Karsli Ceppioğlu S,Yurdun T,Canbakan M

更新日期：2011-01-01 00:00:00

abstract：:The prognosis of uremia patients on continuous ambulatory peritoneal dialysis (CAPD) is related to frequent peritonitis rate. Frequent peritonitis will lead to peritoneum failure, making CAPD unfeasible. We have performed proteomic profiling of peritoneal dialysis effluent samples from a cross-section of CAPD patients...

journal_title：Renal failure

authors： Lin WT,Tsai CC,Chen CY,Lee WJ,Su CC,Wu YJ

更新日期：2008-01-01 00:00:00

abstract：:Purine nucleotide liberation and their metabolic rate of interconversion may be important in the development of hypertension and its renal consequences. In the present study, blood triphosphate (ATP), adenosine diphosphate (ADP), and adenosine monophosphate (AMP) breakdown pathway was evaluated in relation to uric aci...

journal_title：Renal failure

authors： Boban M,Kocic G,Radenkovic S,Pavlovic R,Cvetkovic T,Deljanin-Ilic M,Ilic S,Bobana MD,Djindjic B,Stojanovic D,Sokolovic D,Jevtovic-Stoimenov T

更新日期：2014-05-01 00:00:00

abstract：:This study was aimed to investigate the therapeutic potential of coenzyme Q10 and its combination with sitagliptin in experimentally induced diabetic nephropathy. The diabetic rats were treated with coenzyme Q10 or sitagliptin and their concomitant administration. Various parameters of renal function like serum creati...

journal_title：Renal failure

authors： Maheshwari R,Balaraman R,Sen AK,Shukla D,Seth A

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Crush syndrome developing as a result of earthquake and other natural disasters has been investigated from many angles to date. Data are scarce, however, on cases associated with the spontaneous crash of buildings. This study presents the results on seven rhabdomyolysis patients treated in our clinics out of...

journal_title：Renal failure

authors： Altintepe L,Guney I,Tonbul Z,Türk S,Mazi M,Ağca E,Yeksan M

更新日期：2007-01-01 00:00:00

abstract：:Introduction: This study aimed to investigate the clinical characteristics, risk factors, and outcomes of infection-related hospitalization (IRH) in patients with lupus nephritis (LN) and ANCA glomerulonephritis after intensive immunosuppressive therapy.Methods: Patients diagnosed with LN or ANCA glomerulonephritis wh...

journal_title：Renal failure

authors： Yin P,Li J,Wen Q,Qiu Y,Liang W,Wang J,Yu J,Zhong Z,Yang X,Yu X,Ye Q,Huang F

更新日期：2020-11-01 00:00:00

abstract：:Granulomatous interstitial nephritis (GIN) is a rare disease. Contributing factors such as drugs, sarcoidosis, infections, and paraproteinemia have been reported, and when no obvious contributing factors can be identified, the disease is classified as idiopathic GIN. We managed a patient with idiopathic GIN with an un...

journal_title：Renal failure

authors： Kim SJ,Hee Sung S

更新日期：2010-01-01 00:00:00

abstract：:Hypertonic glycerol injection is one of the most frequently used models of experimental acute renal failure. Late structural changes such as interstitial fibrosis in the renal cortex and tubular atrophy have been detected after severe acute tubular necrosis (ATN). The aim of this study was to investigate the expressio...

journal_title：Renal failure

authors： de Jesus Soares T,Costa RS,de Mattos Coelho R,Alves da Silva CG,Coimbra TM

更新日期：2005-01-01 00:00:00

abstract：:There is limited information on the incidence of acute kidney injury (AKI) in patients with traumatic brain injury (TBI) although AKI may contribute to morbidity and mortality. We investigated the incidence of AKI in patients with moderate and severe TBI and the association of AKI with risk factors and outcomes in the...

journal_title：Renal failure

authors： Moore EM,Bellomo R,Nichol A,Harley N,Macisaac C,Cooper DJ

更新日期：2010-01-01 00:00:00

abstract：:Spontaneous nontraumatic rupture of the kidney (Wunderlich syndrome) is an extremely uncommon condition on hemodialysis. We report a case of 44-year-old hemodialysis patient presented with hemorrhagic shock and a right quadrant abdominal pain to the emergency department. There was no history of trauma. A kidney ruptur...

journal_title：Renal failure

authors： Rountas C,Sioka E,Karagounis A,Golphinopoulos S,Kourti P,Stefanidis I,Zacharoulis D,Tzortzis V

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Renal cystic disorders (RCD) constitute an important and leading cause of end-stage renal disease (ESRD) in children. It can be acquired or inherited; isolated or associated with extrarenal manifestations. The precise diagnosis represents a difficult clinical challenge. METHODS:The aim of this study was to ...

journal_title：Renal failure

authors： Soliman NA,Nabhan MM,Bazaraa HM,Badr AM,Shaheen M

更新日期：2014-06-01 00:00:00

abstract：PURPOSE:Oxidative stress due to hyperglycemia is a major cause of diabetes complications. The aim of this study was to evaluate the effects of pomegranate seed oil (PSO) on serum biochemical parameters, cardiomyopathy and nephropathy induced by diabetes mellitus. METHOD:W/A adult rats were divided into four groups (12...

journal_title：Renal failure

authors： Mollazadeh H,Sadeghnia HR,Hoseini A,Farzadnia M,Boroushaki MT

更新日期：2016-09-01 00:00:00

abstract：AIM:The aim of this study was to evaluate the effects of curcumin in an experimental model of busulfan-induced renal toxicity with emphasis on importance of histological alterations. METHODS:In this study, we utilized 32 adult male Wistar rats (250 ± 10 g). All the animals were divided into four experimental groups ra...

journal_title：Renal failure

authors： Abdollahifar MA,Ebrahimi V,Aliaghaei A,Raoofi A,Khosravi A,Hasani A,Mehdizadeh A,Asadi M

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To assess the safety and clinical efficacy of leflunomide (LEF) and prednisone on refractory nephrotic syndrome (RNS). METHODS:A total of 52 patients with RNS were treated for 24 weeks between 2010 and 2014 in our hospital. In the treated group, 26 patients were treated with LEF and prednisone, and, in the c...

journal_title：Renal failure

authors： Liu Y,Qu X,Chen W,Zhang Y,Liu L

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Peritonitis, the most important limitation of peritoneal dialysis (PD), could be detected by biomarkers in dialysate effluent, representing a noninvasive method to indirectly assess the peritoneum status. The aim of our study was to test high mobility group box 1 (HMGB1) in PD patients, evaluating its role a...

journal_title：Renal failure

authors： Chimenz R,Lacquaniti A,Colavita L,Chirico V,Fede C,Buemi M,Fede C

更新日期：2016-10-01 00:00:00

abstract：:The case of giant renal cyst measuring 30 cm, accompanied by abdominal swelling and erythrocytosis, is presented. A 45-year-old male presented with large abdominal mass, atrophic left kidney, hypertension, and erythrocytosis. The patient underwent multiple preoperative phlebotomies, open extirpation of the cyst, and n...

journal_title：Renal failure

authors： Pejcic T,Hadzi-Djokic J,Markovic B,Naumovic R

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Hypertension very often accompanies progression of chronic kidney disease (CKD) in children. A cross-sectional analysis of hypertension prevalence in dialyzed children in Poland was designed with a comparison with the data previously recorded 10 years earlier. METHODS:Two cohorts of children were analyzed: ...

journal_title：Renal failure

authors： Tkaczyk M,Stańczyk M,Miklaszewska M,Zachwieja K,Wierciński R,Stankiewicz R,Firszt-Adamczyk A,Zachwieja J,Borzęcka H,Zagożdżon I,Leszczyńska B,Medyńska A,Adamczyk P,Szczepańska M,Fendler W

更新日期：2017-11-01 00:00:00