Abstract:
:There is limited information on the incidence of acute kidney injury (AKI) in patients with traumatic brain injury (TBI) although AKI may contribute to morbidity and mortality. We investigated the incidence of AKI in patients with moderate and severe TBI and the association of AKI with risk factors and outcomes in these patients. We studied all TBI patients over 16 years of age admitted to the two designated trauma hospitals in the state of Victoria, Australia from 1 January to 31 December 2008. Patients were included if they had head trauma and presented with a Glasgow coma scale (GCS) <13. Prospectively collected data from the hospital trauma registries, ICUs, and pathology databases were analyzed retrospectively. Risk injury failure loss end (RIFLE) criteria were used to categorize renal function. The incidence of AKI was 9.2% (19/207). Patients who developed AKI were older, had higher severity of illness scores, and a lower GCS. Overall 42.1% of these patients died in hospital compared with 18.1% in patients without AKI. In univariable linear regression analysis, age, severity of illness, and admitting hospital were associated with AKI. After multivariable logistic regression, the occurrence of AKI was associated with age (p < 0.001) and higher APACHE III scores (p = 0.016). AKI is relatively common even in patients with TBI. Its association with age and APACHE III scores helps identify patients at higher risk of AKI.
journal_name
Ren Failjournal_title
Renal failureauthors
Moore EM,Bellomo R,Nichol A,Harley N,Macisaac C,Cooper DJdoi
10.3109/0886022X.2010.510234subject
Has Abstractpub_date
2010-01-01 00:00:00pages
1060-5issue
9eissn
0886-022Xissn
1525-6049journal_volume
32pub_type
杂志文章相关文献
RENAL FAILURE文献大全abstract::Increased vascular calcification and oxidative stress are considered as extra renal risk factors at the pathogenesis cardiovascular events in chronic kidney disease (CKD). We investigated matrix Gla protein (MGP) (T-138C, Glu60X, Thr83Ala) and Klotho (Cys370Ser) gene polymorphisms, serum MGP levels, and oxidative stre...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2011.605534
更新日期:2011-01-01 00:00:00
abstract::Aquaporin-2 protein levels can be detected in the urine of normal of subjects if measured after fluid deprivation. By contrast, in patients with nephrogenic diabetes insipidus caused by mutations in the aquaporin-2 gene, urine aquaporin-2 protein excretion cannot be detected. We propose that properly standardized meas...
journal_title:Renal failure
pub_type: 杂志文章,评审
doi:10.3109/08860229909085095
更新日期:1999-05-01 00:00:00
abstract::Rhabdomyolysis ranges from an asymptomatic illness with elevated creatine kinase levels to a life-threatening condition associated with extreme elevations in creatine kinase, electrolyte imbalances, acute renal failure, and disseminated intravascular coagulation. The most common causes are crush injury, overexertion, ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2013.832856
更新日期:2014-02-01 00:00:00
abstract:PRINCIPLES:Coumadin-induced renal and retroperitoneal hemorrhages are rare. Clinical and laboratory findings are not specific for the diagnosis. Computed tomography (CT) has some advantages in the evaluation of these patients. The aim of this study is to report our experience regarding renal and retroperitoneal hemorrh...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/08860220500530569
更新日期:2006-01-01 00:00:00
abstract:AIM:Novel coronavirus pneumonia (COVID-19) has become pandemic. It brings serious threat to hemodialysis (HD) patients. Therefore, we carried out a study on the clinical characteristics of HD patients with COVID-19. METHODS:We retrospectively analyzed the data of 31 HD patients with COVID-19. The clinical features of ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/0886022X.2020.1796705
更新日期:2020-11-01 00:00:00
abstract::Secondary hyperparathyroidism is one of the most common complications of chronic renal failure (CRF). Its pathogenesis is multifactorial and still not completely understood. Pathological mechanism of hypocalcemia, hyperphosphatemia and calcitriol deficiency are basic characteristics of CRF and main reason for morpholo...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-100103500
更新日期:2001-03-01 00:00:00
abstract::Envenomations by venomous lizards are rare. Monitor lizard bite-induced acute kidney injury (AKI) is a previously unreported complication in humans. A 55-year-old female was bitten on her right leg during farming activity by a monitor lizard (Varanus bengalensis). The patient experienced severe local pain and bleeding...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2013.868223
更新日期:2014-04-01 00:00:00
abstract::Controlling blood pressure in hemodialysis patients is crucial but not always easy. The most common blood pressure measurement method is peri-dialysis measurement, but due to interdialytic blood pressure fluctuations, we are unsure if it is the proper way for evaluating blood pressure. Some studies have shown the supe...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2014.883933
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVE:To investigate the anti proteinuric effect of pentoxifylline in diabetic patients, we prospectively studied in 25 hypertensive type 2 diabetic patients with persistent microalbuminuria and normal renal function the impact of combining pentoxifylline with an angiotensin converting enzyme inhibitor, lisinopril,...
journal_title:Renal failure
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1081/jdi-120021159
更新日期:2003-05-01 00:00:00
abstract::Creation of arteriovenous fistula (AVF) may lead to left ventricle hypertrophy and predispose for development or worsening of heart failure. It was postulated to reduce access blood flow if exceeded 2 L/min or cardiac index was higher than 3.0 L/min/m(2). Numbers of techniques decreasing flow were described. The major...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/0886022X.2016.1184936
更新日期:2016-08-01 00:00:00
abstract::The effect of FK 506 pretreatment on renal ischemia and reperfusion (I/R) injury was investigated. Adult male rats were assigned to one of two groups (20 animals each). Group 1 (controls) received 0.5 mL saline while group 2 received FK 506 (0.3 mg/kg) intravenously 24 h prior to the induction of renal ischemia. After...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860229209106630
更新日期:1992-01-01 00:00:00
abstract::The aim of this investigation was to study the validity of the radionuclide methods in the estimation of kidney function, for prognosis and follow-up of acute renal failure (ARF). In thirty-one ARF patients, the evaluation of glomerular filtration rate (GFR) by 99mTc-DTPA clearance and effective renal plasma flow (ERP...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-100100899
更新日期:2000-01-01 00:00:00
abstract::Recently we demonstrated the effect of fenoldopam on ischemia/reperfusion (I/R) induced NFkappaB mediated pro-inflammatory signal transduction. However, the effect of fenoldopam on I/R-induced apoptosis is not known. We utilized a rat model of acute ischemic nephropathy to test the hypothesis that fenoldopam attenuate...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/08860220600583690
更新日期:2006-01-01 00:00:00
abstract::Toxoplasma gondii is one of the important opportunistic pathogen among solid-organ transplant recipients and hemodialysis patients (HD). This study was aimed to detect toxoplasmosis among 50 renal transplant recipients (RTR), 135 HD and 120 healthy individuals in two cities (Kashan and Qom) that located in the center ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2016.1172940
更新日期:2016-07-01 00:00:00
abstract:INTRODUCTION:Dyslipidemia is one of the onset and risk factors of chronic kidney disease and renal function drop is seen in lipoprotein abnormal animal models. However, the detailed molecular mechanism of renal lipotoxicity has not been clarified. Therefore, the present study aimed to investigate the influence of chole...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/0886022X.2017.1419974
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:Despite the effectiveness of intravenous calcitriol in suppressing parathyroid hormone secretion in patients with uremic hyperparathyroidism, 50% of the patients remain refractory to this treatment. There are conflicting reports regarding the factors that can predict the response to treatment. Technetium-99m...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-120004093
更新日期:2002-03-01 00:00:00
abstract:AIM:To investigate the effects of lentivirus-mediated shRNA targeting collagen type I on the mesangial cells of rats and the feasibility of lentivirus-mediated shRNA delivery through renal parenchyma injection. METHODS:Anti-collagen type I shRNA lentiviral vector was constructed, and rat mesangial cells were transfect...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2011.559679
更新日期:2011-01-01 00:00:00
abstract::Cystatin C is considered an indicator of acute renal failure and also a risk factor of cardiovascular disease. This study was undertaken to examine the relationship of serum cystatin C with C-reactive protein (CRP), lipids, and lipid-related compounds in patients on hemodialysis (HD). Cystatin C, CRP, total cholestero...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/08860220802212973
更新日期:2008-01-01 00:00:00
abstract::Anticoagulants are commonly used to prolong circuit life during continuous hemofiltration. However, a clear correlation between routinely performed blood coagulability tests and circuit life has not been demonstrated. This lack of correlation may derive from the limited ability of such tests to describe the likelihood...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-100100873
更新日期:2000-05-01 00:00:00
abstract::Adiponectin is secreted specifically by adipose tissue. It was reported that the serum adiponectin level was markedly increased in patients with end-stage renal disease and was positively associated with abnormal renal function in type 2 diabetes. Recently, we found that urinary adiponectin level was significantly inc...
journal_title:Renal failure
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::Acute iron poisoning is a common and potentially serious problem in the pediatric population. Early recognition and treatment is crucial for a better outcome and to prevent morbidity and mortality. An 18-year-old female, who had accidental ingestion of 50 tablets of ferrous sulfate (100 mg of elemental iron per 335 mg...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2013.790299
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVES:Chronic kidney disease (CKD) is a major risk factor for cardiovascular disease (CVD). We previously reported renal parenchymal damage in autopsy subjects with stroke or abdominal aortic aneurysm. The aim of this study is to evaluate the relationship between renal histology and clinical characteristics of pat...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2011.605531
更新日期:2011-01-01 00:00:00
abstract::Genetic heterogeneity is the main factor for significant variation in the course of autosomal dominant polycystic kidney disease (ADPKD). PKD1 patients have more severe renal outcomes compared with PKD2 patients. Co-inheritance of a mutation in both genes is associated with more severe phenotypes than that found with ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2014.890010
更新日期:2014-06-01 00:00:00
abstract:INTRODUCTION:In this study, the cause of rapidly deteriorating renal functions in a follow-up period of a 65-year-old female patient, who applied with nephrotic syndrome findings and diagnosed as membranous nephropathy, is presented. CASE REPORT:A 65-year-old patient with findings of nephrotic syndrome had normal kidn...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/08860220802064804
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Human urotensin-II (hU-II) is one of the most potent vasoconstrictors in mammals. To our knowledge, there is no study about the role of U-II in childhood glomerulonephritis. We first determined the expression of h U-II in kidneys of children with chronic glomerular diseases. METHODS:Normal human kidneys wer...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/08860220701392108
更新日期:2007-01-01 00:00:00
abstract::Previously we have shown that the amount of protein in a dietary regimen prior to the induction of renal ischemia will significantly affect the degree of postischemic acute renal failure (Andrews PM, Bates SB: Kidney Int 30:299-303, 1986). The present investigation was undertaken to determine what effect dietary prote...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860229309065566
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVES:Whether uric acid levels were associated with the progression of chronic kidney disease (CKD) remained controversial. This meta-analysis was aimed to assess the effect of lowering serum uric acid therapy on the progression of CKD to clarify the role of uric acid in the progression of CKD indirectly. METHODS...
journal_title:Renal failure
pub_type: 杂志文章,meta分析,评审
doi:10.1080/0886022X.2018.1456463
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:The hemodialysis adequacy is one of the most important issues influencing the survival of patients on maintenance hemodialysis (HD). Assessment of measuring the delivered dialysis dose using clearance x time/volume (Kt/V) index requires multiple blood sampling. New methods for assessment of dialysis dose bas...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/08860220500200262
更新日期:2005-01-01 00:00:00
abstract::Valacyclovir induced neurotoxicity is a life-threatening complication, usually starting 24-48 h after drug-peak serum concentrations. The elderly with impaired renal function seem to be the most susceptible group to valacyclovir neurotoxicity. Although hemodialysis is considered the best method for rapid drug removal,...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2012.743914
更新日期:2013-01-01 00:00:00
abstract::This article describes several topics necessary for understanding the psychological impact of disasters. Topics discussed include characteristics of disaster that impact psychological response, stages of response, factors influencing individual and collective trauma, and important aspects of psychological intervention...
journal_title:Renal failure
pub_type: 杂志文章,评审
doi:10.3109/08860229709109027
更新日期:1997-09-01 00:00:00