Efficacy of leflunomide combined with prednisone in the treatment of refractory nephrotic syndrome.

abstract：:Diabetic nephropathy (DN) is a serious complication of diabetes with a poorly defined etiology and limited treatment options. Early intervention is a key to preventing the progression of DN. Dynamin-related protein 1 (DRP1) regulates mitochondrial morphology by promoting its fission and is involved in the pathogenesis...

journal_title：Renal failure

authors： Zhang L,Ji L,Tang X,Chen X,Li Z,Mi X,Yang L

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Contrast-induced nephropathy (CIN) is a complex syndrome of acute nephropathy that occurs following infusion of intravascular contrast agents, and is associated with an increased risk for adverse cardiovascular events. While there is no ideal biomarker for making an early diagnosis of CIN, we hypothesized th...

journal_title：Renal failure

authors： Gutiérrez-Escolano A,Santacruz-Vázquez E,Gómez-Pérez F

更新日期：2015-01-01 00:00:00

abstract：:Vascular calcification (VC) is an important promoter of cardiovascular disease (CVD) in patients undergoing peritoneal dialysis (PD). Several indices can be used to evaluate VC, including the abdominal aortic calcification index (AACI) and carotid artery intima-media thickness (IMT); however, simpler and lesser expens...

journal_title：Renal failure

authors： Yang N,Yang W,Cui W,Zhou D,Du X,Li L

更新日期：2020-11-01 00:00:00

abstract：:The effect of FK 506 pretreatment on renal ischemia and reperfusion (I/R) injury was investigated. Adult male rats were assigned to one of two groups (20 animals each). Group 1 (controls) received 0.5 mL saline while group 2 received FK 506 (0.3 mg/kg) intravenously 24 h prior to the induction of renal ischemia. After...

journal_title：Renal failure

authors： Van Thiel DH,Sakr M,Zetti G,McClain C

更新日期：1992-01-01 00:00:00

abstract：AIM:Returning to society plays an important role in improving the quality of life in maintenance hemodialysis (MHD) patients, and retention of employment is one of the core enablers. The study is to assess the employment status and to determine the variables for unemployment in Chinese MHD patients. METHODS:Prevalent ...

journal_title：Renal failure

authors： Huang B,Lai B,Xu L,Wang Y,Cao Y,Yan P,Chen J

更新日期：2017-11-01 00:00:00

abstract：:Continuous efforts have been made to find out precise and simple method for determination of glomerular filtration rate (GFR). Cystatin C (cysteine proteinase inhibitor = CyC) is a low molecular weight (LMW) protein which is produced constantly by all nucleated cells independently of different pathological conditions ...

journal_title：Renal failure

authors： Jovanović D,Krstivojević P,Obradović I,Durdević V,Dukanović L

更新日期：2003-01-01 00:00:00

abstract：:Podocyte injury is a vital factor, which induces massive proteinuria. Studies have shown that tacrolimus (TAC) protected podocyte via stabilizing cytoskeleton. Our latest study indicates that calcineurin binding protein 1 (Cabin1) undergoes nuclear translocation during podocytes injury. Whether TAC targets on Cabin1 d...

journal_title：Renal failure

authors： Wen Y,Liu L,Zhou P,Li H,Wang Z,Zhang Y,Liang J

更新日期：2016-01-01 00:00:00

abstract：:Herein, we report a case of acute kidney injury (AKI) due to diarrhea-induced acute tubular necrosis (ATN) in a patient with nephrotic syndrome secondary to biopsy-proven collapsing focal and segmental glomerulosclerosis (FSGS). The clinical picture mimicked rapidly progressive glomerulonephritis (RPGN) and motivated ...

journal_title：Renal failure

authors： Rodamilans MF,Barros LL,Carneiro MM,dos Santos WL,Rocha PN

更新日期：2010-01-01 00:00:00

abstract：:The injection to rats of glycerol, cisplatin, uranyl acetate, sodium dichromate, and mercuric chloride is followed on the third day by acute renal failure. A new approach for quantitative estimation of disturbance of excretory renal function is presented. The decrease in renal function due to uranyl acetate was 77%; s...

journal_title：Renal failure

authors： Natochin YV,Bakhteeva VT,Karpenko LA

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Diabetic kidney disease (DKD) is a leading cause of end-stage renal disease (ESRD). Renin-angiotensin-aldosterone system (RAAS) plays a critical role in the development of DKD with angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) being the mainstay of treatment. System...

journal_title：Renal failure

authors： Dhakarwal P,Agrawal V,Kumar A,Goli KM,Agrawal V

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Long-term peritoneal exposure to high glucose in the peritoneal dialysis (PD) solution may potentiate the development of peritoneal fibrosis in PD patients. The most important factor leading to peritoneal fibrosis may be injury of human peritoneal mesothelial cells (HPMC). Little is known about senescence of...

journal_title：Renal failure

authors： Cao D,Zhang M,Jiang C,Xue L,Sun C

更新日期：2012-01-01 00:00:00

abstract：:Objective: The present study assesses whether phosphodiesterase type 5 (PDE-5) inhibitor or carnitine exert nephroprotective effects against clinical contrast-induced nephropathy (CIN).Materials and Methods: The present study consisted of three groups of CKD patients. The first group was control group, who were treate...

journal_title：Renal failure

authors： Armaly Z,Artol S,Jabbour AR,Saffouri A,Habashi N,Abd Elkadir A,Ghattas N,Farah R,Kinaneh S,Nseir W

更新日期：2019-11-01 00:00:00

abstract：:Envenomations by venomous lizards are rare. Monitor lizard bite-induced acute kidney injury (AKI) is a previously unreported complication in humans. A 55-year-old female was bitten on her right leg during farming activity by a monitor lizard (Varanus bengalensis). The patient experienced severe local pain and bleeding...

journal_title：Renal failure

authors： Vikrant S,Verma BS

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Determination of fluid overload is important in chronic kidney disease. Early diagnosis and treatment of volume overload may decrease morbidity and mortality. We aimed to determine body composition by using bioelectrical impedance analysis, and studying other clinical characteristics, inferior vena cava diam...

journal_title：Renal failure

authors： Yilmaz Z,Yildirim Y,Oto F,Aydin FY,Aydin E,Kadiroglu AK,Yilmaz ME

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:The hemodialysis adequacy is one of the most important issues influencing the survival of patients on maintenance hemodialysis (HD). Assessment of measuring the delivered dialysis dose using clearance x time/volume (Kt/V) index requires multiple blood sampling. New methods for assessment of dialysis dose bas...

journal_title：Renal failure

authors： Racki S,Zaputović L,Maleta I,Grzetić M,Mavrić Z,Devcić B,Vujicić B

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Peritonitis, the most important limitation of peritoneal dialysis (PD), could be detected by biomarkers in dialysate effluent, representing a noninvasive method to indirectly assess the peritoneum status. The aim of our study was to test high mobility group box 1 (HMGB1) in PD patients, evaluating its role a...

journal_title：Renal failure

authors： Chimenz R,Lacquaniti A,Colavita L,Chirico V,Fede C,Buemi M,Fede C

更新日期：2016-10-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection has recently become the major cause of chronic liver disease among patients on chronic hemodialysis. The use of erythropoietin for treatment of anemia has reduced the number of blood transfusions, but the frequency of HCV infection has not declined in hemodialysis units. The exact mod...

journal_title：Renal failure

authors： Harmankaya O,Cetin B,Obek A,Seber E

更新日期：2002-09-01 00:00:00

abstract：:From unpublished experience of clinicians in the rural tropics, the combination of furosemide and dopamine is beneficial in the management of mild acute renal failure in tropical disease. We studied two groups of patients with leptospirosis and mild acute renal failure whose serum creatinine ranged from 2.4 to 5 mg/dL...

journal_title：Renal failure

authors： Niwattayakul K,Sitprija V

更新日期：2007-01-01 00:00:00

abstract：:Hypertonic glycerol injection is one of the most frequently used models of experimental acute renal failure. Late structural changes such as interstitial fibrosis in the renal cortex and tubular atrophy have been detected after severe acute tubular necrosis (ATN). The aim of this study was to investigate the expressio...

journal_title：Renal failure

authors： de Jesus Soares T,Costa RS,de Mattos Coelho R,Alves da Silva CG,Coimbra TM

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Asymmetric dimethylarginine (ADMA) as a uremia toxin is accumulated in end-stage renal disease (ESRD) patients. Elevated ADMA level has been shown to be predictive of cardiovascular diseases (CVDs) and all-cause mortality in ESRD. Therefore, we investigated the removal of ADMA by different dialysis treatment...

journal_title：Renal failure

authors： Zhang DL,Liu J,Liu S,Zhang Y,Liu WH

更新日期：2010-01-01 00:00:00

abstract：AIMS:The use of hemodialysis temporary dual-lumen catheters is often complicated by infections, which may be a significant cause of death among patients with end stage renal disease (ESRD). The aim of this study was to assess the incidence of bacteremia and bacterial colonization related to non-tunneled, non-cuffed, du...

journal_title：Renal failure

authors： de Freitas LW,Neto MM,Nascimento MM,Figueiredo JF

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of urokinase-type plasminogen activator (uPA) on mesangial matrix in the kidney of diabetic rats and its related mechanisms. METHODS:Diabetic Sprague-Dawley (SD) rats induced by intraperitoneal injection of streptozotocin (STZ) were randomly and evenly divided into two groups: DM + ...

journal_title：Renal failure

authors： Cheng H,Chen C,Wang S

更新日期：2014-09-01 00:00:00

abstract：:The rate of hepatitis B virus (HBV) infection is high in the Chinese population, and the implications of HBV infection are widely recognized, and membranous nephropathy is the most common renal lesion to be associated with HBV infection. Minimal change disease (MCD) is one of the most important histopathological chara...

journal_title：Renal failure

authors： Zhou TB,Jiang ZP

更新日期：2015-04-01 00:00:00

abstract：:Microalbumin is a basic biochemical test that is widely used at present. Owing to the concept of point-of-care testing (POCT), there are tools available for analysis of microalbumin. Here, the author performs a brief assessment on weight-turnaround time properties for available POCT for determination of microalbumin i...

journal_title：Renal failure

authors： Wiwanitkit V

更新日期：2010-05-01 00:00:00

abstract：:Polyarteritis nodosa (PAN) is a necrotizing inflammatory vasculitis of small- and medium-sized muscular arteries. Multiple organs, especially the kidney, skin, peripheric nerves, striated muscles, and intestine, are affected. In this case report, a patient with renal and hepatic involvement and axillary and brachial a...

journal_title：Renal failure

authors： Kocyigit I,Koyuncu S,Mavili E,Unal A,Tokmak TT,Cilan H,Kavuncuoglu F,Oymak O,Utas C

更新日期：2011-01-01 00:00:00

abstract：:The proximal convoluted tubule (PCT) is the major target for injury in gentamicin nephrotoxicity but the necrosis is often patchy and focal. The PCT is structurally, functionally, and metabolically heterogeneous, and the possibility of differential vulnerability to gentamicin-induced necrosis based on this heterogenei...

journal_title：Renal failure

authors： Shanley PF,Burke TJ

更新日期：1990-01-01 00:00:00

abstract：:The risk of tuberculosis (TB) is significantly increased in chronic kidney disease (CKD). Data on TB in CKD in the UK are sparse; most information stems from countries with high background prevalence. The aim of this study was to estimate the incidence of TB in CKD patients in South East London and to describe the epi...

journal_title：Renal failure

authors： Ostermann M,Palchaudhuri P,Riding A,Begum P,Milburn HJ

更新日期：2016-01-01 00:00:00

abstract：:Experimental perfusions of isolated rat kidneys were performed with flow rates adjusted to produce comparable glomerular filtration rates (GFR) in control and experimental groups. The experimental perfusate, consisting of Krebs-Ringer bicarbonate (KRB) containing 3.5% (uncrosslinked) stroma-free hemoglobin (SFH) plus ...

journal_title：Renal failure

authors： Millis RM,Barber JD,Anderson WA,Dehkordi O

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:This aim of this multi-centric cross-sectional study was to assess the nutritional status in Indian chronic kidney disease (CKD) patients and to compare the nutritional indicators between stage 5 dialyzed (CKD-D) patients below the poverty line (BPL), and stage 3-4 non-dialyzed (CKD-ND) patients above (APL) ...

journal_title：Renal failure

authors： Vijayan M,Abraham G,Alex ME,Vijayshree N,Reddy Y,Fernando E,Mathew M,Nair S,Yuvaraj A

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Human urotensin-II (hU-II) is one of the most potent vasoconstrictors in mammals. To our knowledge, there is no study about the role of U-II in childhood glomerulonephritis. We first determined the expression of h U-II in kidneys of children with chronic glomerular diseases. METHODS:Normal human kidneys wer...

journal_title：Renal failure

authors： Balat A,Karakök M,Yilmaz K,Kibar Y

更新日期：2007-01-01 00:00:00