Inhibition to DRP1 translocation can mitigate p38 MAPK-signaling pathway activation in GMC induced by hyperglycemia.

abstract：AIM:Returning to society plays an important role in improving the quality of life in maintenance hemodialysis (MHD) patients, and retention of employment is one of the core enablers. The study is to assess the employment status and to determine the variables for unemployment in Chinese MHD patients. METHODS:Prevalent ...

journal_title：Renal failure

authors： Huang B,Lai B,Xu L,Wang Y,Cao Y,Yan P,Chen J

更新日期：2017-11-01 00:00:00

abstract：:We previously described a method to measure GFR in conscious spontaneously voiding rats. This method circumvents the need for anesthesia and for bladder instrumentation. It's main principle is the correction of renal 125I-iothalamate clearance for incomplete urine collection by the ratio of plasma and renal clearance ...

journal_title：Renal failure

authors： de Vries PA,Navis G,de Jong PE,de Zeeuw D

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Sirolimus has been considered to be a non-nephrotoxic agent. It may delay graft function due to a potential hindrance of the recovery from acute tubular necrosis. It remains controversial as to whether the concomitant administration of sirolimus (SRL) with calcineurin inhibitors delays graft function in Asia...

journal_title：Renal failure

authors： Hsu HJ,Tian YC,Chen YC,Lai BC,Fang JT,Yang CW,Wu MS

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:There are little data on the incidence of acute renal failure (ARF) from India due to the absence of central registry. The etiology, course, and outcome of ARF differ in various parts of India. Significant trend changes were reported even within a same center over a period of time. AIM:To find out the epide...

journal_title：Renal failure

authors： Jayakumar M,Prabahar MR,Fernando EM,Manorajan R,Venkatraman R,Balaraman V

更新日期：2006-01-01 00:00:00

abstract：:Chromogranin A (CGA) is a low MW (49,000) acidic hydrophilic protein. It is synthesized in the chromaffm granules of the neuroendocrine cells, and has been found circulating in the blood of healthy subjects. The aim of this study was to assess the relationship between serum levels of CGA and renal function. One hundre...

journal_title：Renal failure

authors： Tramonti G,Ferdeghini M,Annichiarico C,Norpoth M,Donadio C,Bianchi R,Bianchi C

更新日期：2001-05-01 00:00:00

abstract：:Recent studies show that clinically stable renal transplant recipients have an increased prevalence of hyperhomocysteinemia (hyperHcy), but the mechanism of this disorder has not yet been elucidated. The aim of the present study was to evaluate the factors associated with hyperHcy after a successful renal transplantat...

journal_title：Renal failure

authors： Simić-Ogrizović S,Radivojević D,Radovic M,Lezaic V,Mirković D,Babić D,Dukanović L

更新日期：2006-01-01 00:00:00

abstract：:We studied gene expression for transforming growth factor (TGF)-alpha, epidermal growth factor (EGF), heparin binding (HB) EGF, and the EGF receptor following acute renal failure induced by mercuric chloride administration to gain insight into potential mechanisms of renal repair. Twenty four hours after HgCl2, 2 mg/k...

journal_title：Renal failure

authors： Hise MK,Liu L,Salmanullah M,Drachenberg CI,Papadimitriou JC,Rohan RM

更新日期：2000-01-01 00:00:00

abstract：RATIONAL:Obstetrical complications are the commonest causes of Renal Cortical Necrosis (RCN). However, the overall incidence of RCN in obstetric acute kidney injury in developing countries has been decreasing in recent years. OBJECTIVE:The aim of this study was to evaluate the changing profile of RCN in obstetric AKI ...

journal_title：Renal failure

authors： Prakash J,Pant P,Singh AK,Sriniwas S,Singh VP,Singh U

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:An increased red blood cell (RBC) phosphatidylserine (PS) exposure in uremic patients was found that could promote macrophage recognition and decrease RBC survival time. Furthermore, a reduced red cell life span was found to contribute anemia in patients with renal failure. It is therefore possible to hypoth...

journal_title：Renal failure

authors： Bi SH,Cheng LT,Wang T

更新日期：2006-01-01 00:00:00

abstract：:Idiopathic nephrotic syndrome (NS) associated with focal segmental glomerulosclerosis (FSGS) and severe renal function impairment is usually refractory to the conventional treatment and progresses to end-stage renal disease. Herein, we reported 10 patients with NS-FSGS who had initially had CCr 34 +/- 12 mL/min/1.73 m...

journal_title：Renal failure

authors： Futrakul N,Siriviriyakul P,Deekajorndej T,Futrakul P

更新日期：2004-05-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is associated with an increased prevalence of chronic kidney disease in patients with type 1 diabetes. The aim of this study was to explore the relationship between markers of NAFLD, namely concentrations of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alka...

journal_title：Renal failure

authors： Bulum T,Kolarić B,Duvnjak M,Duvnjak L

更新日期：2014-04-01 00:00:00

abstract：:The present study was undertaken to verify the hypothesis that infusion of atrial natriuretic peptide (ANP) might lower preload and be beneficial in the treatment of pulmonary congestion even without a diuresis in patients with acute renal failure (ARF) secondary to severe congestive heart failure (CHF). We studied 22...

journal_title：Renal failure

authors： Seta K,Hayashi T,Sugawara A,Kasuno K,Watanabe S,Sumi Y,Kijima Y,Kawaguchi K,Kotake C,Seo T,Toda T,Kuwahara T

更新日期：1998-09-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection has recently become the major cause of chronic liver disease among patients on chronic hemodialysis. The use of erythropoietin for treatment of anemia has reduced the number of blood transfusions, but the frequency of HCV infection has not declined in hemodialysis units. The exact mod...

journal_title：Renal failure

authors： Harmankaya O,Cetin B,Obek A,Seber E

更新日期：2002-09-01 00:00:00

abstract：:Renal ischemia reperfusion injury (IRI) is a major problem, currently without treatments in clinical use. This reflects the failure of animal models to mimic the severity of IRI observed in clinical practice. Most described models lack both the ability to inflict a permanent reduction in renal function and the sensiti...

journal_title：Renal failure

authors： Whalen H,Shiels P,Littlejohn M,Clancy M

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Experimental studies have shown that increased levels of parathyroid hormone (PTH) in uremia may cause elevation of intracellular calcium, predisposing to insulin resistance and lipid metabolism abnormalities. Administration of calcium-channel blockers (CCBs) in these models protects against the development ...

journal_title：Renal failure

authors： Zanos S,Mitsopoulos E,Sakellariou G

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND/AIM:There is little information on the development of anemia in the early stages of chronic kidney disease. The aim of this study was to analyze the onset of renal anemia in a cohort of initially nonanemic chronic kidney disease patients followed up in nephrology clinics. METHODS:This epidemiological, prosp...

journal_title：Renal failure

authors： Portolés J,Castelao AM,Gorriz JL,Tato AM,de Alvaro F

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To investigate the expression and clinical significance of both matrix metalloproteinase-2 (MMP-2) and its tissue inhibitor (tissue inhibitor of metalloproteinase-2 (TIMP-2)) in tunica media of radial artery in uremic patients. METHODS:The modified radial arteries from 80 uremic patients during internal arte...

journal_title：Renal failure

authors： Shan A,Zhou C,He Y,Feng W,Chen G,Zhong G

更新日期：2013-01-01 00:00:00

abstract：:Purpose: Typically, IgA nephropathy is a slowly progressive type of glomerulonephritis. High-grade proteinuria and hypertension are predictors of reduced kidney function. However, we found some normotensive patients with mild proteinuria could exhibit impaired renal function at the time of IgAN diagnosis. We therefore...

journal_title：Renal failure

authors： Tan M,Fang J,Xu Q,Zhang C,Zou G,Wang M,Li W

更新日期：2019-11-01 00:00:00

abstract：:Herein, we report a case of acute kidney injury (AKI) due to diarrhea-induced acute tubular necrosis (ATN) in a patient with nephrotic syndrome secondary to biopsy-proven collapsing focal and segmental glomerulosclerosis (FSGS). The clinical picture mimicked rapidly progressive glomerulonephritis (RPGN) and motivated ...

journal_title：Renal failure

authors： Rodamilans MF,Barros LL,Carneiro MM,dos Santos WL,Rocha PN

更新日期：2010-01-01 00:00:00

abstract：:Cold preservation has greatly facilitated the use of cadaveric kidneys for renal transplantation, but, clearly, damage occurs during both the preservation episode and the reperfusion phase (following transplantation). The aims of this study were twofold: to develop an in vivo model that was capable of evaluating renal...

journal_title：Renal failure

authors： Saba H,Munusamy S,Macmillan-Crow LA

更新日期：2008-01-01 00:00:00

abstract：:Arteriosclerosis is characterized by stiffening of arteries. The incremental elastic modulus (Einc) measurement is a good marker of arterial wall stiffness. Metabolic, inflammatory and hemodynamic alterations cause structural changes and vascular complications in end stage renal disease. The aim of the present study w...

journal_title：Renal failure

authors： Seyrek N,Balal M,Karayaylali I,Paydaş S,Aikimbaev K,Cetiner S,Seydaoglu G

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:The kidney is a major site for the inactivation, degradation, and clearance of a variety of peptide hormones. It has been shown that the uremia increases or decreases gastrointestinal system (GIS) hormones. Moreover, studies investigating the serum GIS hormones levels in chronic renal failure (CRF) were cond...

journal_title：Renal failure

authors： Borazan A,Cavdar Z,Saglam F

更新日期：2007-01-01 00:00:00

abstract：:Despite advanced techniques of renal replacement therapy the overall mortality of patients with ARF is still high. The majority of patients with ARF requiring dialysis are those with nontraumatic ARF. In a retrospective study we compared the causes of nontraumatic ARF, the risk factors for the development of renal fai...

journal_title：Renal failure

authors： Schmekal B,Pichler R,Biesenbach G

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:To describe the epidemiologic features of acute renal failure related to pregnancy (PRARF) and to evaluate its prognostic impact. METHODS:Retrospective study conducted in a Tunisian intensive care unit over a period of 17 years (1995-2011). Women were included if they were more than 20 weeks pregnant and were ...

journal_title：Renal failure

authors： Bouaziz M,Chaari A,Turki O,Dammak H,Chelly H,Ammar R,Nasri A,Ben Algia N,Bahloul M,Ben Hamida C

更新日期：2013-10-01 00:00:00

abstract：:Pentoxifylline (PTX) has been reported to inhibit TNF-alpha production and prevent several types of acute renal failure. This study was undertaken to determine the effect of PTX on the cisplatin-induced acute renal failure in rabbits. Rabbits received a single injection of cisplatin (5 mg/kg, i.p.) with or without PTX...

journal_title：Renal failure

authors： Kim YK,Choi TR,Kwon CH,Kim JH,Woo JS,Jung JS

更新日期：2003-11-01 00:00:00

abstract：:Abnormal glucose metabolism in uremia may result from a complex interplay between decreased insulin secretion and insulin resistance. Recent studies report beneficial effect of biotin administration in glucose metabolism in diabetic animals and in a small number of patients with diabetes mellitus. The aim of the prese...

journal_title：Renal failure

authors： Koutsikos D,Fourtounas C,Kapetanaki A,Agroyannis B,Tzanatos H,Rammos G,Kopelias I,Bosiolis B,Bovoleti O,Darema M,Sallum G

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Spontaneous crescentic glomerulonephritis (SCG)/Kj mice are a candidate for suitable animal model of human pauci-immune crescentic glomerulonephritis (GN). In the present study, we used renal biopsy technique and analyzed time sequence correlations among crescent formation and glomerular neutrophil infiltrat...

journal_title：Renal failure

authors： Miyazawa S,Saiga K,Nemoto K,Mae T,Hotta O

更新日期：2002-09-01 00:00:00

abstract：:Diabetic nephropathy (DN) has become the most common pathogenesis of end-stage renal disease. Plasminogen activator inhibitor-1 (PAI-1) plays an important role in the pathogenesis of DN. A meta-analysis was conducted to investigate the association between 4 G/5 G variants in the PAI-1 gene and DN susceptibility. Datab...

journal_title：Renal failure

authors： Xue C,Nie W,Zhou C,Yu F,Wang DM,Dai B,Mei CL

更新日期：2014-04-01 00:00:00

abstract：:We investigated the mechanism of impaired serum opsonic activity in patients suffering from chronic renal failure (CRF). Prehemodialysis pooled serum from CRF patients was fractionated using Sephadex G-50 gel chromatography, and the effects of the obtained fractions on serum opsonic activity were examined using lumino...

journal_title：Renal failure

authors： Kikuchi T,Nigawara K,Sugawara K,Nakaji S,Abe T,Satoh H

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:The pathogenesis of the development of IgA nephropathy has not been clear up to now. At present, some studies revealed that the mTOR pathway may participate in IgA nephropathy; however, the mechanism has not been systematically studied. In this study, we established an IgAN rat model to investigate the prote...

journal_title：Renal failure

authors： Guo N,Liu S,Bow LM,Cui X,Zhang L,Xu S,Lu S,Tian J

更新日期：2019-11-01 00:00:00