A novel rodent model of severe renal ischemia reperfusion injury.

abstract：:In this prospective study, we aimed to determine the protective antioxidant role of alpha-lipoic acid (ALA) on development of contrast-induced nephropathy (CIN) in diabetic patients undergoing coronary angiography. Seventy-eight diabetic patients undergoing coronary angiography were included. Thirty-nine patients were...

journal_title：Renal failure

authors： Cicek M,Yıldırır A,Okyay K,Yazici AC,Aydinalp A,Kanyilmaz S,Muderrisoglu H

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Intima-Media-Thickness of the carotid artery wall (cIMT) is a strong predictor of cardiovascular (CV) disease. The aim of this study was to investigate the significance of cIMT as an independent prognostic factor for CV morbidity and mortality in patients with chronic kidney disease (CKD) and diabetes mellit...

journal_title：Renal failure

authors： Roumeliotis A,Roumeliotis S,Panagoutsos S,Theodoridis M,Argyriou C,Tavridou A,Georgiadis GS

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:In this study, it was aimed to determine the effects of alfuzosin on experimentally generated unilateral partial ureteropelvic junction obstruction (UPO) in rats. MATERIALS AND METHODS:Thirty Long-Evans rats were randomly allocated into five groups. In control group (C), nothing was performed; in group Sham...

journal_title：Renal failure

authors： Kose F,Turkyilmaz Z,Sonmez K,Karabulut R,Poyraz A,Gulbahar O,Aral A,Damar C,Kaya C,Can Basaklar A

更新日期：2016-09-01 00:00:00

abstract：:Diabetic nephropathy (DN) is a serious complication of diabetes with a poorly defined etiology and limited treatment options. Early intervention is a key to preventing the progression of DN. Dynamin-related protein 1 (DRP1) regulates mitochondrial morphology by promoting its fission and is involved in the pathogenesis...

journal_title：Renal failure

authors： Zhang L,Ji L,Tang X,Chen X,Li Z,Mi X,Yang L

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The pathogenesis of the development of IgA nephropathy has not been clear up to now. At present, some studies revealed that the mTOR pathway may participate in IgA nephropathy; however, the mechanism has not been systematically studied. In this study, we established an IgAN rat model to investigate the prote...

journal_title：Renal failure

authors： Guo N,Liu S,Bow LM,Cui X,Zhang L,Xu S,Lu S,Tian J

更新日期：2019-11-01 00:00:00

abstract：:Despite advanced techniques of renal replacement therapy the overall mortality of patients with ARF is still high. The majority of patients with ARF requiring dialysis are those with nontraumatic ARF. In a retrospective study we compared the causes of nontraumatic ARF, the risk factors for the development of renal fai...

journal_title：Renal failure

authors： Schmekal B,Pichler R,Biesenbach G

更新日期：2004-01-01 00:00:00

abstract：:During times of war or natural disasters, rhabdomyolysis leading to acute kidney injury (AKI) can assume epidemic proportions. Fasudil attenuates ischemia/reperfusion-induced AKI. We investigated the therapeutic effect of an early application of fasudil on AKI induced by rhabdomyolysis and explored the potential mecha...

journal_title：Renal failure

authors： Wang YD,Zhang L,Cai GY,Zhang XG,Lv Y,Hong Q,Shi SZ,Yin Z,Liu XF,Chen XM

更新日期：2011-01-01 00:00:00

abstract：:Psoriasis, being limited to the skin, is generally a chronic inflammatory disorder. Several glomerular diseases have been distinguished due to renal histological findings of psoriatic patients to date. The underlying pathogenetic mechanisms of these associations remain unclear because of the limited number of cases. W...

journal_title：Renal failure

authors： Ceri M,Kurultak I,Unverdi S,Altay M,Duranay M

更新日期：2010-06-01 00:00:00

abstract：:Chronic kidney disease (CKD) is a world-wide public health problem. The purpose of this study was to identify the role of some controversial potential risk factors in development of CKD. "Community Complex Health Screening" is a large-scale, free, health program for individuals ≥40 years of age that has been available...

journal_title：Renal failure

authors： Hsu YC,Lee PH,Lei CC,Shih YH,Lin CL

更新日期：2014-04-01 00:00:00

abstract：:Autosomal dominant polycystic disease (ADPKD) is one of the most common monogenic disorders, and globally is among the most common hereditary causes of end stage kidney disease. Until recently, the causes of this disease remained obscure. However, in the past decade there have been enormous advances in the understandi...

journal_title：Renal failure

authors： Kazancioglu R,Gursu M

更新日期：2015-05-01 00:00:00

abstract：:We evaluated amount and composition of amino acids in supplementation of hyperalimentation from the standpoint of whether it may improve nutrition and/or reduce the indexes of uremia such as BUN. Rats with established uremia, by 5/6 nephrectomy, were treated with various isocaloric solutions containing different amoun...

journal_title：Renal failure

authors： Kikuchi T,Tanaka H,Kokuba Y,Sato M

更新日期：1994-01-01 00:00:00

abstract：:Polyarteritis nodosa (PAN) is a necrotizing inflammatory vasculitis of small- and medium-sized muscular arteries. Multiple organs, especially the kidney, skin, peripheric nerves, striated muscles, and intestine, are affected. In this case report, a patient with renal and hepatic involvement and axillary and brachial a...

journal_title：Renal failure

authors： Kocyigit I,Koyuncu S,Mavili E,Unal A,Tokmak TT,Cilan H,Kavuncuoglu F,Oymak O,Utas C

更新日期：2011-01-01 00:00:00

abstract：:This article reviews our experience with 111 pediatric patients following open-heart surgery over 1-year period. Peritoneal dialysis was required in 34 of 111 children (30.6%). We randomly selected 33 patients who did not require peritoneal dialysis as control group. The indications of dialysis were oligoanuria and/or...

journal_title：Renal failure

authors： Baskin E,Gulleroglu KS,Saygili A,Aslamaci S,Varan B,Tokel K

更新日期：2010-01-01 00:00:00

abstract：:The ability to predict the rate of progression of renal parenchymal disease may help in its clinical management. We undertook characterization of urinary macrophages obtained from patients with various renal diseases paying special attention to the differentiation from non-progressive to progressive renal diseases. A ...

journal_title：Renal failure

authors： Hotta O,Kitamura H,Taguma Y

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:To investigate the prevalence and risk factors for chronic kidney disease (CKD) among community elderly population in Shanghai, China, in order to provide early diagnosis and treatment of CKD, and improve the quality of life for elderly people. METHODS:In all, 24,886 residents (≥65 years old) were selected f...

journal_title：Renal failure

authors： Huang YP,Zheng T,Zhang DH,Chen LY,Mao PJ

更新日期：2016-11-01 00:00:00

abstract：:Podocyte injury is a vital factor, which induces massive proteinuria. Studies have shown that tacrolimus (TAC) protected podocyte via stabilizing cytoskeleton. Our latest study indicates that calcineurin binding protein 1 (Cabin1) undergoes nuclear translocation during podocytes injury. Whether TAC targets on Cabin1 d...

journal_title：Renal failure

authors： Wen Y,Liu L,Zhou P,Li H,Wang Z,Zhang Y,Liang J

更新日期：2016-01-01 00:00:00

abstract：:The nephrotoxicity of amikacin (AK) was prevented with pentoxifylline (PTX) in a rat model. Rats were received a single injection of AK (1.2 g/kg, i.p.) with or without PTX pretreatment (25 mg/kg, orally). Renal morphology was investigated by light microscopy. Tissue samples and trunk blood were also obtained to deter...

journal_title：Renal failure

authors： Ozer MK,Asci H,Oncu M,Yesilot S,Savran M,Bayram D,Cicek E

更新日期：2009-01-01 00:00:00

abstract：:To evaluate the role of the inducible nitric oxide synthase (iNOS), selective nuclear factor-kB (NF-kB), and p38-mitogene-activated protein kinase (p38-MAPK) on hyperoxaluria-induced oxidative stress and stone formation in rat kidneys. The rats were divided into five groups: group 1, control group; group 2: ethylene g...

journal_title：Renal failure

authors： Ilbey YO,Ozbek E,Simsek A,Cekmen M,Somay A,Tasci AI

更新日期：2009-01-01 00:00:00

abstract：:Creation of arteriovenous fistula (AVF) may lead to left ventricle hypertrophy and predispose for development or worsening of heart failure. It was postulated to reduce access blood flow if exceeded 2 L/min or cardiac index was higher than 3.0 L/min/m(2). Numbers of techniques decreasing flow were described. The major...

journal_title：Renal failure

authors： Letachowicz K,Kusztal M,Gołębiowski T,Letachowicz W,Weyde W,Klinger M

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Cardiac valve calcification (CVC) and left ventricular (LV) alterations are frequent complication in end-stage renal disease (ESRD). We determined the prevalence of CVC and LV hypertrophy (LVH) in ESRD patients before renal replacement therapy and 12 months after peritoneal dialysis (PD). METHODS:A prospect...

journal_title：Renal failure

authors： Rebić D,Rašić S,Hamzić-Mehmedbašić A,Džemidžić J,Kurtalić E

更新日期：2015-01-01 00:00:00

abstract：:Acute renal failure (ARF) is one of the most frequent and potentially life threatening complications following bone marrow transplantation (BMT). Several renal syndromes that occur are either unique or occur with a disproportionate frequency post-BMT. Clinically ARF can be classified according to the time of onset pos...

journal_title：Renal failure

authors： Pulla B,Barri YM,Anaissie E

更新日期：1998-05-01 00:00:00

abstract：AIM:The relation of chronic kidney disease (CKD) with metabolic, psychiatric and endocrinologic disorder is well-known. Depressive mood and sexual dysfunction are frequently observed as renal functions deteriorate. We aimed to analyze the relationship of sexual dysfunction, depressive mood and life quality in patients ...

journal_title：Renal failure

authors： Esen B,Kahvecioglu S,Atay AE,Ozgen G,Okumus MM,Seyahi N,Sit D,Kadioglu P

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:Whether uric acid levels were associated with the progression of chronic kidney disease (CKD) remained controversial. This meta-analysis was aimed to assess the effect of lowering serum uric acid therapy on the progression of CKD to clarify the role of uric acid in the progression of CKD indirectly. METHODS...

journal_title：Renal failure

authors： Liu X,Zhai T,Ma R,Luo C,Wang H,Liu L

更新日期：2018-11-01 00:00:00

abstract：:Renal involvement is an unusual but significant Behcet´s disease (BD) complication and AA amyloidosis appears to be the most common etiology. IL-6 is a pro-inflammatory cytokine with an important role in AA amyloidosis development. Tocilizumab (TCZ) is a humanized anti-IL-6 receptor antibody that has emerged as an eff...

journal_title：Renal failure

authors： Redondo-Pachón MD,Enríquez R,Sirvent AE,Andrada E,Noguera-Pons R,Millán I,Amorós F

更新日期：2013-01-01 00:00:00

abstract：:This report describes a patient who developed acute rhabdomyolysis and acute renal failure following the application of MAST trousers associated with an overdose of diflunisal. This association has not previously been reported. ...

journal_title：Renal failure

authors： Pilmore H,Walker RJ

更新日期：1993-01-01 00:00:00

abstract：INTRODUCTION:Preimplantation biopsy provides a window on the state of the renal allograft. In this study, the prognostic value of frozen section preimplantation graft biopsy was estimated and compared to regularly processed formalin-fixed biopsy. MATERIALS AND METHODS:Seventy-four renal allograft recipients were studi...

journal_title：Renal failure

authors： Goumenos DS,Kalliakmani P,Tsamandas AC,Maroulis I,Savidaki E,Fokaefs E,Papachristou E,Karavias D,Vlachojannis JG

更新日期：2010-05-01 00:00:00

abstract：:Chromogranin A (CGA) is a low MW (49,000) acidic hydrophilic protein. It is synthesized in the chromaffm granules of the neuroendocrine cells, and has been found circulating in the blood of healthy subjects. The aim of this study was to assess the relationship between serum levels of CGA and renal function. One hundre...

journal_title：Renal failure

authors： Tramonti G,Ferdeghini M,Annichiarico C,Norpoth M,Donadio C,Bianchi R,Bianchi C

更新日期：2001-05-01 00:00:00

abstract：:The effect of FK 506 pretreatment on renal ischemia and reperfusion (I/R) injury was investigated. Adult male rats were assigned to one of two groups (20 animals each). Group 1 (controls) received 0.5 mL saline while group 2 received FK 506 (0.3 mg/kg) intravenously 24 h prior to the induction of renal ischemia. After...

journal_title：Renal failure

authors： Van Thiel DH,Sakr M,Zetti G,McClain C

更新日期：1992-01-01 00:00:00

abstract：UNLABELLED:Conventional urea kinetic modeling and peritoneal equilibration test (PET) were performed on 73 patients undergoing CAPD in order to determine factors influencing morbidity. Dialysis adequacy (KT/V, creatinine clearance, efficacy number) and nutrition (PCR, nPCR, creatinine generation rate, body mass index, ...

journal_title：Renal failure

authors： Heaf J

更新日期：1995-09-01 00:00:00

abstract：:The present study was undertaken to examine the role of arachidonic acid (AA) metabolites in hypoxia/reoxygenation (H/R)-induced renal cell injury in rabbit renal cortical slices using AA metabolic inhibitors. Inhibitors of cyclooxygenase (indomethacin and diclofenac sodium) and lipoxygenase pathways (nordihydroguaiar...

journal_title：Renal failure

authors： Kim YK,Hwang MY,Woo JS,Jung JS,Lee SH

更新日期：2000-03-01 00:00:00