Challenges in clinical-pathologic correlations: acute tubular necrosis in a patient with collapsing focal and segmental glomerulosclerosis mimicking rapidly progressive glomerulonephritis.

Abstract:

:Herein, we report a case of acute kidney injury (AKI) due to diarrhea-induced acute tubular necrosis (ATN) in a patient with nephrotic syndrome secondary to biopsy-proven collapsing focal and segmental glomerulosclerosis (FSGS). The clinical picture mimicked rapidly progressive glomerulonephritis (RPGN) and motivated pulse therapy with methylprednisolone and cyclophosphamide. The case presentation is followed by a brief overview of the epidemiology of AKI in nephrotic syndrome as well as a discussion of its risk factors and potential mechanisms involved.

journal_name

Ren Fail

journal_title

Renal failure

authors

Rodamilans MF,Barros LL,Carneiro MM,dos Santos WL,Rocha PN

doi

10.3109/0886022X.2010.501931

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

1005-8

issue

8

eissn

0886-022X

issn

1525-6049

journal_volume

32

pub_type

杂志文章
  • Impact of pretreatment with carnitine and tadalafil on contrast-induced nephropathy in CKD patients.

    abstract::Objective: The present study assesses whether phosphodiesterase type 5 (PDE-5) inhibitor or carnitine exert nephroprotective effects against clinical contrast-induced nephropathy (CIN).Materials and Methods: The present study consisted of three groups of CKD patients. The first group was control group, who were treate...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2019.1669459

    authors: Armaly Z,Artol S,Jabbour AR,Saffouri A,Habashi N,Abd Elkadir A,Ghattas N,Farah R,Kinaneh S,Nseir W

    更新日期:2019-11-01 00:00:00

  • Urinary transforming growth factor-beta1 excretion in renal allograft recipients during the early post-transplantation period.

    abstract:BACKGROUND:Transforming growth factor-beta1 (TGF-beta1), the major fibrogenic growth factor, is implicated in the pathogenesis of renal scarring in experimental and clinical nephropathies as well as in chronic allograft nephropathy. In this study we examined the pattern of changes of TGF-beta1 excretion in the urine an...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1081/jdi-120022547

    authors: Goumenos DS,Tsakas S,Karavias D,Savidaki I,Karatzas T,Vlachojannis JG

    更新日期:2003-07-01 00:00:00

  • Role of glutathione for cisplatin nephrotoxicity in young and adult rats.

    abstract::Investigations were done in 10- and 55-day-old Wistar rats. Glutathione (GSH) level in kidney was decreased by 8 mmol buthionine sulfoximine (BSO)/100 g BW. There was no effect on the renal function and nephrotoxicity of cisplatin (0.6 mg CP/100 g BW) in adult rats. In young rats BSO treatment was followed by nephroto...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229309046144

    authors: Appenroth D,Winnefeld K

    更新日期:1993-01-01 00:00:00

  • Long-term effects of small doses of calcitriol in hemodialysis patients with moderate secondary hyperparathyroidism.

    abstract::Prevention of secondary hyperparathyroidism (SHPTH) and treatment of the moderate cases by small p.os doses of Vitamin D has not been thoroughly investigated on the long term, while large doses of Vitamin D have been successful in the short term treatment of this entity. We administered calcitriol p.os 0.5-1.0 microgr...

    journal_title:Renal failure

    pub_type: 临床试验,杂志文章

    doi:10.3109/08860229909066984

    authors: Vlassopoulos D,Noussias C,Revenas K,Hadjilouka-Mantaka A,Arvanitis D,Tzortzis G,Hadjiconstantinou V

    更新日期:1999-03-01 00:00:00

  • Tacrolimus restores podocyte injury and stabilizes the expression of Cabin1 in 5/6 nephrectomized rats.

    abstract::Podocyte injury is a vital factor, which induces massive proteinuria. Studies have shown that tacrolimus (TAC) protected podocyte via stabilizing cytoskeleton. Our latest study indicates that calcineurin binding protein 1 (Cabin1) undergoes nuclear translocation during podocytes injury. Whether TAC targets on Cabin1 d...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2016.1148936

    authors: Wen Y,Liu L,Zhou P,Li H,Wang Z,Zhang Y,Liang J

    更新日期:2016-01-01 00:00:00

  • The effects of spironolactone on nephron function in patients with diabetic nephropathy.

    abstract::Increasing evidence suggests that circulating aldosterone per se contributes directly to renal and cardiovascular diseases. We sought to evaluate the effects of a three-month treatment with 25 mg spironolactone, an aldosterone receptor antagonist, on nephron function in 20 type II diabetic patients with persistent mic...

    journal_title:Renal failure

    pub_type: 临床试验,杂志文章

    doi:10.1080/08860220802389342

    authors: Ustundag A,Tugrul A,Ustundag S,Sut N,Demirkan B

    更新日期:2008-01-01 00:00:00

  • Relation between exhaled nitric oxide and left ventricular performance in chronic hemodialysis patients.

    abstract:INTRODUCTION:End-stage renal disease is the most debilitating condition for patients with renal diseases. Cardiovascular disease is the leading cause of death in these patients. It has been shown that nitric oxide (NO) increases in renal failure and hemodialysis patients and could be correlated with cardiovascular dise...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2013.830225

    authors: Ansarin K,Toufan M,Namdar H,Etemadi J,Habibzadeh A,Valinejad M,Shoja MM,Ghabili K

    更新日期:2014-02-01 00:00:00

  • Reversible renal failure due to bilateral renal sarcoma in a patient with acute myeloid leukemia.

    abstract::A 68-year-old male presented with acute myeloid leukemia, renal failure, hypokalemia, and enlarged kidneys on renal ultrasound. Renal biopsy revealed massive leukemic infiltration of the kidney. After systemic chemotherapy, the patient developed tumor lysis syndrome followed by a phase of proximal tubule dysfunction p...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220902972187

    authors: Rüger W,Kruip MJ,Betjes MG

    更新日期:2009-01-01 00:00:00

  • Assessment of hemodialysis adequacy by ionic dialysance: comparison to standard method of urea removal.

    abstract:BACKGROUND:The hemodialysis adequacy is one of the most important issues influencing the survival of patients on maintenance hemodialysis (HD). Assessment of measuring the delivered dialysis dose using clearance x time/volume (Kt/V) index requires multiple blood sampling. New methods for assessment of dialysis dose bas...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220500200262

    authors: Racki S,Zaputović L,Maleta I,Grzetić M,Mavrić Z,Devcić B,Vujicić B

    更新日期:2005-01-01 00:00:00

  • Acute renal failure caused by nontraumatic rhabdomyolysis.

    abstract::Nontraumatic rhabdomyolysis may be associated with severe metabolic disturbances. In particular, previous literature has described a 8-20% incidence of acute renal failure in rhabdomyolysis. The aim of this study was to evaluate our experience on 11 patients with acute renal failure treated by high-efficiency daily he...

    journal_title:Renal failure

    pub_type: 临床试验,杂志文章

    doi:10.3109/08860229709047729

    authors: Tozzo C,Mazzarella V,Splendiani G,Casciani CU

    更新日期:1997-05-01 00:00:00

  • Defining peritoneal dialysis adequacy: Kt/Vurea revisited.

    abstract:BACKGROUND:Although adequate peritoneal dialysis is not well defined, Kt/Vurea has been used as an index, and various values have been proposed. However, conflicting evidence existed regarding the appropriateness of using Kt/Vurea to define dialysis adequacy and its optimal value. Therefore, the present study performed...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220601166586

    authors: Zhe XW,Shan YS,Cheng L,Tian XK,Wang T

    更新日期:2007-01-01 00:00:00

  • The effects of proteinuria on urinary cystatin-C and glomerular filtration rate calculated by serum cystatin-C.

    abstract:BACKGROUND:The measurement of glomerular filtration rate (GFR) applying serum creatinine (Cr) does not reflect the GFR of patients accurately, and thus recently, studies on the measurement of GFR applying serum cystatin-C (Cys-C) have been conducted. We investigated the relationship between Cys-C and proteinuria in pat...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2012.672154

    authors: Kim JS,Kim MK,Lee JY,Han BG,Choi SO,Yang JW

    更新日期:2012-01-01 00:00:00

  • Parathyroid hormone levels, calcium-channel blockers, and the dyslipidemia of nondiabetic hemodialysis patients.

    abstract:BACKGROUND:Experimental studies have shown that increased levels of parathyroid hormone (PTH) in uremia may cause elevation of intracellular calcium, predisposing to insulin resistance and lipid metabolism abnormalities. Administration of calcium-channel blockers (CCBs) in these models protects against the development ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:

    authors: Zanos S,Mitsopoulos E,Sakellariou G

    更新日期:2005-01-01 00:00:00

  • Significant correlation between left ventricular systolic and diastolic dysfunction and decreased glomerular filtration rate.

    abstract::Cardiac dysfunction portends a poor prognosis in renal failure and vice versa. Functional abnormalities of heart in patients with renal insufficiency were frequently noted. The aim of this study is to assess the relationship between left ventricular systolic and diastolic function and renal function in patients with v...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2011.618792

    authors: Hsieh MC,Su HM,Wang SY,Tsai DH,Lin SD,Chen SC,Chen HC

    更新日期:2011-01-01 00:00:00

  • Cola-colored dialysate as a gastrointestinal sequelae of cardiac surgery in a patient who underwent peritoneal dialysis.

    abstract::The discoloration of effluent peritoneal dialysate, which is transparent in origin, is seen in some particular conditions including chyloperitoneum, calcium channel blocker usage, hemoperitoneum, perforated cholecystitis, iron administration, and hemorrhagic pancreatitis. We report a case of a 60-year-old woman who un...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2012.711731

    authors: Ling EK,Lin BS,Chiang SS,Tsai MH

    更新日期:2012-01-01 00:00:00

  • Efficacy of leflunomide combined with prednisone in the treatment of refractory nephrotic syndrome.

    abstract:OBJECTIVE:To assess the safety and clinical efficacy of leflunomide (LEF) and prednisone on refractory nephrotic syndrome (RNS). METHODS:A total of 52 patients with RNS were treated for 24 weeks between 2010 and 2014 in our hospital. In the treated group, 26 patients were treated with LEF and prednisone, and, in the c...

    journal_title:Renal failure

    pub_type: 杂志文章,随机对照试验

    doi:10.3109/0886022X.2016.1172917

    authors: Liu Y,Qu X,Chen W,Zhang Y,Liu L

    更新日期:2016-11-01 00:00:00

  • Erythropoietin production in patients with chronic renal failure.

    abstract::Studies were performed to reexamine the response of erythropoietin (Epo) production to acute hypoxic stimuli in patients with end-stage renal disease (ESRD). In the absence of acute bleeding or hypoxia, the serum Epo level in ESRD was similar to that of normal subjects despite severe anemia. In 11 dialysis patients wi...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229409044892

    authors: Kato A,Hishida A,Kumagai H,Furuya R,Nakajima T,Honda N

    更新日期:1994-01-01 00:00:00

  • Renal cortical necrosis is a disappearing entity in obstetric acute kidney injury in developing countries: our three decade of experience from India.

    abstract:RATIONAL:Obstetrical complications are the commonest causes of Renal Cortical Necrosis (RCN). However, the overall incidence of RCN in obstetric acute kidney injury in developing countries has been decreasing in recent years. OBJECTIVE:The aim of this study was to evaluate the changing profile of RCN in obstetric AKI ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2015.1062340

    authors: Prakash J,Pant P,Singh AK,Sriniwas S,Singh VP,Singh U

    更新日期:2015-08-01 00:00:00

  • Superior prognostic value of soluble suppression of tumorigenicity 2 for the short-term mortality of maintenance hemodialysis patients compared with NT-proBNP: a prospective cohort study.

    abstract::Background: Both soluble suppression of tumorigenicity 2 (sST2) and N-terminal pro-brain natriuretic peptide (NT-proBNP) are promising biomarkers associated with the adverse clinical outcomes of dialysis patients. Our research aims at exploring and comparing the roles of sST2 and NT-proBNP in predicting the short-term...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2020.1767648

    authors: Wang Z,Chen Z,Yu H,Ma X,Zhang C,Qu B,Zhang W,Chen X

    更新日期:2020-11-01 00:00:00

  • Can delivery dialysis dose affect survival of acute kidney injury patients?

    abstract:UNLABELLED:Intensity of dialysis dose in acute kidney injury (AKI) might benefit critically ill patients. The aim of this study was to evaluate the effect of intermittent hemodialysis (IHD) dose on mortality in patients with AKI. METHODS:Prospective observational study was performed on AKI patients treated with IHD. T...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2012.697444

    authors: Abrão JM,Ponce D,de Brito GA,Balbi AL

    更新日期:2012-01-01 00:00:00

  • Long-term efficacy and safety of quadruple therapy in childhood diffuse proliferative lupus nephritis.

    abstract::In this study, we evaluated the frequency, clinical presentation, treatment protocols, prognostic factors, and outcome in children with diffuse proliferative lupus nephritis (DPLN). Between June 1990 and December 2004, 46 patients were diagnosed to have systemic lupus erythematosus (SLE), and 26 of them (56.5%) were f...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220802132171

    authors: Demircin G,Oner A,Erdoğan O,Delibaş A,Baysun S,Bülbül M,Bek K,Oksal A

    更新日期:2008-01-01 00:00:00

  • Relationship of serum cystatin C with C-reactive protein and apolipoprotein A1 in patients on hemodialysis.

    abstract::Cystatin C is considered an indicator of acute renal failure and also a risk factor of cardiovascular disease. This study was undertaken to examine the relationship of serum cystatin C with C-reactive protein (CRP), lipids, and lipid-related compounds in patients on hemodialysis (HD). Cystatin C, CRP, total cholestero...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220802212973

    authors: Samouilidou EC,Grapsa E

    更新日期:2008-01-01 00:00:00

  • Nephroprotective effect of Withania somnifera: a dose-dependent study.

    abstract::In the present study, we investigated the protective effect of Withania somnifera, an indigenous medicinal herb used in ayurvedic traditional systems for more than 3000 years in India, on gentamicin (GEN)-induced nephrotoxicity. The root extract of three different doses of W. somnifera (viz., 250, 500, and 750 mg/kg) ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860220903150320

    authors: Jeyanthi T,Subramanian P

    更新日期:2009-01-01 00:00:00

  • Coumadin-induced renal and retroperitoneal hemorrhage.

    abstract:PRINCIPLES:Coumadin-induced renal and retroperitoneal hemorrhages are rare. Clinical and laboratory findings are not specific for the diagnosis. Computed tomography (CT) has some advantages in the evaluation of these patients. The aim of this study is to report our experience regarding renal and retroperitoneal hemorrh...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220500530569

    authors: Danaci M,Kesici GE,Kesici H,Polat C,Belet U

    更新日期:2006-01-01 00:00:00

  • Vitamin D deficiency, insulin resistance, and ventricular hypertrophy in the early stages of chronic kidney disease.

    abstract:BACKGROUND:Chronic kidney disease (CKD) is associated with markedly increased cardiovascular (CV) risk. This increase is not fully explained by traditional CV risk factors but may in part be mediated by nontraditional risk factors, such as inadequate vitamin D (vit D) levels and insulin resistance (IR). Although IR is ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2013.832308

    authors: Lai S,Coppola B,Dimko M,Galani A,Innico G,Frassetti N,Mariotti A

    更新日期:2014-02-01 00:00:00

  • Comparing long-term outcomes between early and delayed initiation of peritoneal dialysis following catheter implantation.

    abstract:AIM:The aim of this study was to compare peritonitis rates, peritoneal dialysis technique survival and patient survival between patients who started peritoneal dialysis earlier than 14 days (early starters) and 14 days or more (delayed starters) after insertion of a Tenckhoff catheter. METHODS:Observational analysis w...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2016.1165069

    authors: Pai MF,Yang JY,Chen HY,Hsu SP,Chiu YL,Wu HY,Tsai WC,Peng YS

    更新日期:2016-07-01 00:00:00

  • Osmotic diuretics and hemodilution in postischemic renal failure.

    abstract::In the acute phase of ischemic renal failure, the severe depression of the glomerular filtration rate (GFR) is due to obstruction of the tubules by cells and cell debris rejected from the proximal tubules, a blockade which can be prevented at least partly, by treatment with osmotic diuretics. The isosthenuria, the sec...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229209106632

    authors: Wolgast M,Bayati A,Hellberg O,Källskog O,Nygren K

    更新日期:1992-01-01 00:00:00

  • Association of CYP3A variants with kidney transplant outcomes.

    abstract::Cyclosporine is used extensively in kidney transplantation and is a substrate for cytochrome P450 enzymes. The role of cytochrome p450 polymorphisms in kidney transplant outcome has not yet been fully elucidated. We investigate the clinical impact of single nucleotide polymorphisms in CYP3A4, CYP3A5, PPARα, and POR*28...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2015.1007013

    authors: Traynor C,Conlon P Jr,Phelan PJ,O'Kelly P,Elens L,McCormack M,Cavalleri G,Comber H,van Schaik RH,Conlon PJ

    更新日期:2015-05-01 00:00:00

  • Coexisting glomerular IgA deposition and IgG-kappa multiple myeloma.

    abstract::Multiple myeloma (MM) is a common malignancy that often results in many kinds of kidney injuries for the abnormal monoclonal immunoglobulin. Here, we present an IgG-kappa type MM case accompanied by renal IgA deposition combined with IgG-kappa. The patient was treated with prednisone plus mycophenolate mofetil, and go...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2014.930656

    authors: Wang F,Xing T,Li J,Zhang ZG,Wang N

    更新日期:2014-09-01 00:00:00

  • Imbalanced plasma ACE and ACE2 level in the uremic patients with cardiovascular diseases and its change during a single hemodialysis session.

    abstract:BACKGROUND:The renin-angiotensin system (RAS) has significant influences on heart and renal disease progression. Angiotensin converting enzyme (ACE) and angiotensin converting enzyme II (ACE2) are major peptidases of RAS components and play counteracting functions through angiotensin II (Ang II)/ATIR and angiotensin-(1...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2017.1398665

    authors: Yang CW,Lu LC,Chang CC,Cho CC,Hsieh WY,Tsai CH,Lin YC,Lin CS

    更新日期:2017-11-01 00:00:00