Nephroprotective effect of Withania somnifera: a dose-dependent study.

abstract：AIM:When peritoneal fibrosis (PF) causes ultrafiltration failure in peritoneal dialysis (PD) patients, PD has to be discontinued. Currently, there is no effective way to relieve PF. In this study, we aimed to determine whether miR-15a-5p is involved in PF and to determine the underlying mechanism. METHODS:Six normal r...

journal_title：Renal failure

authors： He Q,Wen L,Wang L,Zhang Y,Yu W,Zhang F,Zhang W,Xiao J,Wen X,Zhao Z

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Genetic polymorphism of endothelial nitric oxide synthase (eNOS) has been implicated in the risk of diabetic nephropathy (DN), but the published findings were inconsistent. We performed a comprehensive meta-analysis to derive a more precise estimation of the association between genetic polymorphisms of eNOS ...

journal_title：Renal failure

authors： Zhang Y,Xiao HQ,Zeng XT,Zuo HX,Xu YC

更新日期：2015-11-01 00:00:00

abstract：:Cardiovascular problems are a major cause of morbidity and mortality in patients with autosomal dominant polycystic kidney disease (ADPKD). Endothelial dysfunction (ED), which is an early manifestation of vascular injury, has been shown in patients with ADPKD. Statins have a beneficial effect in the reversal of ED. Th...

journal_title：Renal failure

authors： Namli S,Oflaz H,Turgut F,Alisir S,Tufan F,Ucar A,Mercanoglu F,Ecder T

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Advanced glycation end products (AGEs) have biological properties that may contribute to the mortality of children on hemodialysis (HD). This study examines the relationship of LMW fluorescence AGEs, oxidized LDL (ox-LDL), soluble receptor AGE (sRAGE) as markers of oxidative stress in children with end stage...

journal_title：Renal failure

authors： El-Saeed GS,Fadel F,Elshamaa MF,Galal RE,Elghoroury EA,Nasr SA,Thabet EH,Abdelrahman SM

更新日期：2015-01-01 00:00:00

abstract：:Transforming growth factor-β1 (TGF-β1) is a crucial factor implicated in the development of renal inflammation and tubulointerstitial fibrosis (TIF). The cytokine interleukin 22 (IL-22) was previously reported to involve in the pathogenesis of chronic inflammatory diseases, however recent studies showed that IL-22 cou...

journal_title：Renal failure

authors： Tang R,Xiao X,Lu Y,Li H,Zhou Q,Kwadwo Nuro-Gyina P,Li X

更新日期：2020-11-01 00:00:00

abstract：:In the growing animal, K deficiency (KD) retards body growth, but paradoxically stimulates renal growth. If KD persists, interstitial infiltrates appear and eventually tubulointerstitial fibrosis develops. In patients with chronic KD, renal cysts may form and with time tubulointerstitial disease with renal failure dev...

journal_title：Renal failure

authors： Fervenza F,Tsao T,Rabkin R

更新日期：2001-05-01 00:00:00

abstract：:Urinary N-acetyl-β-d-glucosaminidase (NAG) has been suggested as a marker for early diabetic nephropathy. This study aimed to prospectively investigate the relationship between asymptomatic leukocyturia (ASL) and NAG in women. One hundred and five female outpatients aged 31-86 years were selected for a 10-year follow-...

journal_title：Renal failure

authors： Sekimizu K,Suzuki T,Igari Y,Okazaki M,Hashimoto M,Suzuki K,Ouchi M,Watanabe K,Nakano H,Oba K

更新日期：2012-01-01 00:00:00

abstract：:We evaluated amount and composition of amino acids in supplementation of hyperalimentation from the standpoint of whether it may improve nutrition and/or reduce the indexes of uremia such as BUN. Rats with established uremia, by 5/6 nephrectomy, were treated with various isocaloric solutions containing different amoun...

journal_title：Renal failure

authors： Kikuchi T,Tanaka H,Kokuba Y,Sato M

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Previous studies have found significant stressors experienced by nurses working in hemodialysis units. The purpose of this study was to determine the burnout levels of hemodialysis nurses working in hemodialysis units and their relation with some sociodemographic variables. METHODS:The study was conducted b...

journal_title：Renal failure

authors： Kavurmacı M,Cantekin I,Tan M

更新日期：2014-08-01 00:00:00

abstract：:The characteristics of two established renal cell lines (LLC-PKI and OK) and of primary cultures of rabbit and human proximal tubule cells are described by summarizing the literature about specific properties retained by these cells in culture. Furthermore, comparative biochemical and functional properties are present...

journal_title：Renal failure

authors： Toutain H,Morin JP

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Diabetic kidney disease (DKD) is a leading cause of end-stage renal disease (ESRD). Renin-angiotensin-aldosterone system (RAAS) plays a critical role in the development of DKD with angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) being the mainstay of treatment. System...

journal_title：Renal failure

authors： Dhakarwal P,Agrawal V,Kumar A,Goli KM,Agrawal V

更新日期：2014-07-01 00:00:00

abstract：:Anticoagulants are commonly used to prolong circuit life during continuous hemofiltration. However, a clear correlation between routinely performed blood coagulability tests and circuit life has not been demonstrated. This lack of correlation may derive from the limited ability of such tests to describe the likelihood...

journal_title：Renal failure

authors： Baldwin I,Tan HK,Bridge N,Bellomo R

更新日期：2000-05-01 00:00:00

abstract：:Cyclosporine is used extensively in kidney transplantation and is a substrate for cytochrome P450 enzymes. The role of cytochrome p450 polymorphisms in kidney transplant outcome has not yet been fully elucidated. We investigate the clinical impact of single nucleotide polymorphisms in CYP3A4, CYP3A5, PPARα, and POR*28...

journal_title：Renal failure

authors： Traynor C,Conlon P Jr,Phelan PJ,O'Kelly P,Elens L,McCormack M,Cavalleri G,Comber H,van Schaik RH,Conlon PJ

更新日期：2015-05-01 00:00:00

abstract：AIM:The aim of the present study was to investigate the value of the urine cell glycoprotein 1 (PC-1), aminopeptidase N (APN), N-acetyl-beta-D-glucosaminidase (NAGA), and dipeptidylpeptidase IV (DPP IV) in the evaluation of tubular damage in patients with primary glomerulonephritis, diabetic nephropathy, and lupus neph...

journal_title：Renal failure

authors： Mitic B,Lazarevic G,Vlahovic P,Rajic M,Stefanovic V

更新日期：2008-01-01 00:00:00

abstract：:During exercise, the plasma urate levels and urinary excretion increase due to the enhanced purine degradation in skeletal muscle. Although urate transporter-1 (URAT1) is the main transporter responsible for the reabsorption of filtered urate, potential changes in its activity and expression during exercise have not b...

journal_title：Renal failure

authors： Cirrik S,Yavuzer BU,Oner G

更新日期：2010-01-01 00:00:00

abstract：:In chronic renal failure (CRF), phosphate (Pi) retention may lead to secondary hyperparathyroidism and progression to end-stage renal disease (ESRD). Dietary phosphorus restriction or phosphate binders can slow progression in experimental CRF. Conversely, diets high in phosphorus can accelerate the progression toward ...

journal_title：Renal failure

authors： Loghman-Adham M,Motock GT

更新日期：1996-11-01 00:00:00

abstract：:Purpose: Typically, IgA nephropathy is a slowly progressive type of glomerulonephritis. High-grade proteinuria and hypertension are predictors of reduced kidney function. However, we found some normotensive patients with mild proteinuria could exhibit impaired renal function at the time of IgAN diagnosis. We therefore...

journal_title：Renal failure

authors： Tan M,Fang J,Xu Q,Zhang C,Zou G,Wang M,Li W

更新日期：2019-11-01 00:00:00

abstract：:Uncertainty of measurement is the numeric expression of the errors associated with all measurements taken in clinical laboratories. Serum creatinine concentration is the most common diagnostic marker for acute kidney injury. The goal of this study was to determine the effect of the uncertainty of measurement of serum ...

journal_title：Renal failure

authors： Kin Tekce B,Tekce H,Aktas G,Uyeturk U

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:Organic solvents are liquid substances commonly used in everyday life at home and in industrial workplaces. These solvents are found primarily in paint as thinner. Because other narcotics are hard to find, thinner is used as a narcotic especially among youngsters of low socioeconomic level. The aim of this...

journal_title：Renal failure

authors： Toros AB,Toros SZ,Aker F,Ersoz F,Derin A,Kesici B,Ozel L

更新日期：2011-01-01 00:00:00

abstract：:The present study was undertaken to verify the hypothesis that infusion of atrial natriuretic peptide (ANP) might lower preload and be beneficial in the treatment of pulmonary congestion even without a diuresis in patients with acute renal failure (ARF) secondary to severe congestive heart failure (CHF). We studied 22...

journal_title：Renal failure

authors： Seta K,Hayashi T,Sugawara A,Kasuno K,Watanabe S,Sumi Y,Kijima Y,Kawaguchi K,Kotake C,Seo T,Toda T,Kuwahara T

更新日期：1998-09-01 00:00:00

abstract：:Acute renal failure is the most common complication of rhabdomyolysis, with an 8-20% reported incidence. In particular, rhabdomyolysis associated with acute renal failure is frequently observed in critically ill patients, with a 6-16% reported incidence in Intensive Care Units. Dialytic treatment is necessary to corre...

journal_title：Renal failure

authors： Splendiani G,Mazzarella V,Cipriani S,Pollicita S,Rodio F,Casciani CU

更新日期：2001-03-01 00:00:00

abstract：:Increased vascular calcification and oxidative stress are considered as extra renal risk factors at the pathogenesis cardiovascular events in chronic kidney disease (CKD). We investigated matrix Gla protein (MGP) (T-138C, Glu60X, Thr83Ala) and Klotho (Cys370Ser) gene polymorphisms, serum MGP levels, and oxidative stre...

journal_title：Renal failure

authors： Karsli Ceppioğlu S,Yurdun T,Canbakan M

更新日期：2011-01-01 00:00:00

abstract：:The role of the kidney in the control of blood pressure has been convincingly demonstrated by several studies. Recent evidence has suggested that subtle acquired tubulointerstitial injury may cause a defect in sodium excretion function, thus leading to salt-sensitive hypertension. There are no reports, however, examin...

journal_title：Renal failure

authors： de Magalhães Sartim R,Fantinato Menegon L,de Almeida AR,Rocha Gontijo JA,Aline Boer P

更新日期：2006-01-01 00:00:00

abstract：:Granulomatous interstitial nephritis (GIN) is a rare disease. Contributing factors such as drugs, sarcoidosis, infections, and paraproteinemia have been reported, and when no obvious contributing factors can be identified, the disease is classified as idiopathic GIN. We managed a patient with idiopathic GIN with an un...

journal_title：Renal failure

authors： Kim SJ,Hee Sung S

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Sleep disturbances and cardiovascular autonomic dysfunction are major complications of hemodialysis (HD). The goal of this study is to identify clinical, heart rate variability (HRV) or laboratory parameters that are independently associated with subjective sleep quality. PATIENT AND METHODS:Forty-six sta...

journal_title：Renal failure

authors： Wei CY,Chung TC,Wu SC,Chung CF,Wu WP

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To assess the safety and clinical efficacy of leflunomide (LEF) and prednisone on refractory nephrotic syndrome (RNS). METHODS:A total of 52 patients with RNS were treated for 24 weeks between 2010 and 2014 in our hospital. In the treated group, 26 patients were treated with LEF and prednisone, and, in the c...

journal_title：Renal failure

authors： Liu Y,Qu X,Chen W,Zhang Y,Liu L

更新日期：2016-11-01 00:00:00

abstract：:Background: Renal interstitial fibrosis is a common pathway of chronic kidney disease to end-stage renal disease, which is characterized by an imbalance between the synthesis and degradation of the collagen-rich extracellular matrix (ECM). While, discoidin domain receptor 2 (DDR2) can be activated when it binds to som...

journal_title：Renal failure

authors： Li X,Bu X,Yan F,Wang F,Wei D,Yuan J,Zheng W,Su J,Yuan J

更新日期：2019-11-01 00:00:00

abstract：:Pentoxifylline (PTX) has been reported to inhibit TNF-alpha production and prevent several types of acute renal failure. This study was undertaken to determine the effect of PTX on the cisplatin-induced acute renal failure in rabbits. Rabbits received a single injection of cisplatin (5 mg/kg, i.p.) with or without PTX...

journal_title：Renal failure

authors： Kim YK,Choi TR,Kwon CH,Kim JH,Woo JS,Jung JS

更新日期：2003-11-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is associated with an increased prevalence of chronic kidney disease in patients with type 1 diabetes. The aim of this study was to explore the relationship between markers of NAFLD, namely concentrations of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alka...

journal_title：Renal failure

authors： Bulum T,Kolarić B,Duvnjak M,Duvnjak L

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:The association between poor intraoperative glycemic control and postoperative acute kidney injury (AKI) in adult cardiac surgery has been observed, but data in the pediatrics remain unknown. We performed a hypothesis that intraoperative hyperglycemia and/or wider glycemic fluctuation were associated with the...

journal_title：Renal failure

authors： Hu GH,Duan L,Jiang M,Zhang CL,Duan YY

更新日期：2018-11-01 00:00:00