Beneficial effect of pentoxifylline on cisplatin-induced acute renal failure in rabbits.

abstract：:Aldosterone is reported to promote fibrosis of multiple organs. Recent studies showed that Na+-H+ exchanger isoform 1 (NHE1) was involved in mineralocorticoid-induced tissue fibrosis. The present study examined the role of NHE1 in aldosterone-induced glomerulosclerosis in rats. SD male rats were subjected to 5/6 nephr...

journal_title：Renal failure

authors： Zhang M,Chen J,Liu S,You L,Lin S,Gu Y

更新日期：2009-01-01 00:00:00

abstract：:Recently we demonstrated the effect of fenoldopam on ischemia/reperfusion (I/R) induced NFkappaB mediated pro-inflammatory signal transduction. However, the effect of fenoldopam on I/R-induced apoptosis is not known. We utilized a rat model of acute ischemic nephropathy to test the hypothesis that fenoldopam attenuate...

journal_title：Renal failure

authors： Aravindan N,Cata JP,Dougherty PM,Shaw AD

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Contrast-induced nephropathy (CIN) is a complex syndrome of acute nephropathy that occurs following infusion of intravascular contrast agents, and is associated with an increased risk for adverse cardiovascular events. While there is no ideal biomarker for making an early diagnosis of CIN, we hypothesized th...

journal_title：Renal failure

authors： Gutiérrez-Escolano A,Santacruz-Vázquez E,Gómez-Pérez F

更新日期：2015-01-01 00:00:00

abstract：:Recently, we demonstrated that furosemide improves renal hemodynamics and attenuates ischemia/reperfusion (I/R)-associated changes in angiogenesis-related gene expression. However, the effect of furosemide on I/R-induced apoptosis is not known. We utilized a rat model of acute ischemic nephropathy to test the hypothes...

journal_title：Renal failure

authors： Aravindan N,Aravindan S,Riedel BJ,Weng HR,Shaw AD

更新日期：2007-01-01 00:00:00

abstract：:The injection to rats of glycerol, cisplatin, uranyl acetate, sodium dichromate, and mercuric chloride is followed on the third day by acute renal failure. A new approach for quantitative estimation of disturbance of excretory renal function is presented. The decrease in renal function due to uranyl acetate was 77%; s...

journal_title：Renal failure

authors： Natochin YV,Bakhteeva VT,Karpenko LA

更新日期：1994-11-01 00:00:00

abstract：:Cardiac dysfunction portends a poor prognosis in renal failure and vice versa. Functional abnormalities of heart in patients with renal insufficiency were frequently noted. The aim of this study is to assess the relationship between left ventricular systolic and diastolic function and renal function in patients with v...

journal_title：Renal failure

authors： Hsieh MC,Su HM,Wang SY,Tsai DH,Lin SD,Chen SC,Chen HC

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The goal of this study was to define the clinical and histological differences in new-onset IgA nephropathy between young adults and the elderly. METHODS:We retrospectively examined renal biopsy findings, clinical features at presentation and outcomes in 82 young adults (mean age 30.3+/-10.2 years) and 17 e...

journal_title：Renal failure

authors： Wen YK,Chen ML

更新日期：2010-01-01 00:00:00

abstract：:At least 372 people developed crush syndrome after they were injured by the Great Hanshin-Awaji Earthquake. Of these, 23 were transferred to Osaka City General Hospital from the disaster area. The serum creatinine kinase (CK) of each of the 23 patients exceeded 10,000 IU/L. Sixteen of these patients were treated with ...

journal_title：Renal failure

authors： Shigemoto T,Rinka H,Matsuo Y,Kaji A,Tsukioka K,Ukai T,Shimaoka H

更新日期：1997-09-01 00:00:00

abstract：AIM:The aim of this study was to evaluate the effects of curcumin in an experimental model of busulfan-induced renal toxicity with emphasis on importance of histological alterations. METHODS:In this study, we utilized 32 adult male Wistar rats (250 ± 10 g). All the animals were divided into four experimental groups ra...

journal_title：Renal failure

authors： Abdollahifar MA,Ebrahimi V,Aliaghaei A,Raoofi A,Khosravi A,Hasani A,Mehdizadeh A,Asadi M

更新日期：2020-11-01 00:00:00

abstract：:Genetic heterogeneity is the main factor for significant variation in the course of autosomal dominant polycystic kidney disease (ADPKD). PKD1 patients have more severe renal outcomes compared with PKD2 patients. Co-inheritance of a mutation in both genes is associated with more severe phenotypes than that found with ...

journal_title：Renal failure

authors： Yu C,Li J,Yuan Z,Liu S,Zou L

更新日期：2014-06-01 00:00:00

abstract：AIM:Endoplasmic reticulum (ER) stress and unfolded protein response (UPR) are implicated in many fibrotic diseases, including renal fibrosis. Whether Ginsenoside-Rg1 (G-Rg1) could attenuate renal fibrosis via suppression of ER stress and UPR has not been reported. The aim of this study was to explore the effect of G-Rg...

journal_title：Renal failure

authors： Li SS,Ye JM,Deng ZY,Yu LX,Gu XX,Liu QF

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:In order to evaluate the clinical and pathological characteristics of diuretics associated acute kidney injury (AKI) and its management. METHODS:We performed a retrospective study including 131 cases that diagnosed as diuretics associated AKI from 1 January 1999 to 1 January 2010 in Ruijin Hospital affiliate...

journal_title：Renal failure

authors： Wu X,Zhang W,Ren H,Chen X,Xie J,Chen N

更新日期：2014-08-01 00:00:00

abstract：:Renal biopsy data indicate that tubular epithelial cells serve as a reservoir for HIV-1 infection. We studied the effect of HIV-1 gp120 envelope gene expression on tubular cell apoptosis. HIV-1 gp120 was expressed in a lentiviral vector pHR-CMV-IRES2-EGFP-DeltaB. This plasmid construct was used to produce pseudotyped ...

journal_title：Renal failure

authors： Vashistha H,Husain M,Kumar D,Singhal PC

更新日期：2009-01-01 00:00:00

abstract：:Aquaporin-2 protein levels can be detected in the urine of normal of subjects if measured after fluid deprivation. By contrast, in patients with nephrogenic diabetes insipidus caused by mutations in the aquaporin-2 gene, urine aquaporin-2 protein excretion cannot be detected. We propose that properly standardized meas...

journal_title：Renal failure

authors： Sisson D,Batlle D

更新日期：1999-05-01 00:00:00

abstract：:Dyslipoproteinemia and oxidative modification of low-density lipoprotein (oxLDL) contribute to the development of oxidative stress and atherosclerosis in chronic kidney disease (CKD). On the contrary, high-density lipoprotein cholesterol (HDL-C), especially HDL3-C subtype, has protective effect against oxidative damag...

journal_title：Renal failure

authors： Samouilidou EC,Karpouza AP,Kostopoulos V,Bakirtzi T,Pantelias K,Petras D,Tzanatou-Exarchou H,J Grapsa E

更新日期：2012-01-01 00:00:00

abstract：:Left ventricular (LV) diastolic function was found to be a significant predictor of cardiovascular events and general mortality in dialysis. Studies have indicated that dialysate calcium concentrations were significantly associated with cardiac function. However, the relationship between low calcium dialysate and LV d...

journal_title：Renal failure

authors： Wang Z,Wen Y,Liang J,Liang X,Shi W

更新日期：2016-11-01 00:00:00

abstract：:Envenomations by venomous lizards are rare. Monitor lizard bite-induced acute kidney injury (AKI) is a previously unreported complication in humans. A 55-year-old female was bitten on her right leg during farming activity by a monitor lizard (Varanus bengalensis). The patient experienced severe local pain and bleeding...

journal_title：Renal failure

authors： Vikrant S,Verma BS

更新日期：2014-04-01 00:00:00

abstract：:Our study is a prospective one conducted at Al-Amiri Hospital and including all new cases of chronic renal disease (CRD) seen at the capital area of Kuwait between 1 January 1999 and 30 December 2003. Diagnosis of CRD was based on clinical, laboratory, and radiological features. Kidney biopsies were done when indicate...

journal_title：Renal failure

authors： El-Reshaid W,El-Reshaid K,Kapoor M,Hakim A

更新日期：2005-01-01 00:00:00

abstract：:The characteristics of two established renal cell lines (LLC-PKI and OK) and of primary cultures of rabbit and human proximal tubule cells are described by summarizing the literature about specific properties retained by these cells in culture. Furthermore, comparative biochemical and functional properties are present...

journal_title：Renal failure

authors： Toutain H,Morin JP

更新日期：1992-01-01 00:00:00

abstract：:Atrial Natriuretic Peptide (ANP), has protective effect on the outcome of acute renal failure in animals when infused over short periods of time. Escherichia Coli heat-stable enterotoxin (STa) acts on a particulate guanylate cyclase receptors leading to an increase in cytosolic cGMP similar to ANP. STa has longer dura...

journal_title：Renal failure

authors： Abdulla HM

更新日期：2000-01-01 00:00:00

abstract：:Vascular calcification (VC) is an important promoter of cardiovascular disease (CVD) in patients undergoing peritoneal dialysis (PD). Several indices can be used to evaluate VC, including the abdominal aortic calcification index (AACI) and carotid artery intima-media thickness (IMT); however, simpler and lesser expens...

journal_title：Renal failure

authors： Yang N,Yang W,Cui W,Zhou D,Du X,Li L

更新日期：2020-11-01 00:00:00

abstract：:Valacyclovir induced neurotoxicity is a life-threatening complication, usually starting 24-48 h after drug-peak serum concentrations. The elderly with impaired renal function seem to be the most susceptible group to valacyclovir neurotoxicity. Although hemodialysis is considered the best method for rapid drug removal,...

journal_title：Renal failure

authors： Pipili C,Pantelias K,Deda E,Tsiamalos P,Kostis E,Grapsa E

更新日期：2013-01-01 00:00:00

abstract：:A growing body of evidence supports the notion that calcium antagonists exert a renal protective effect. Calcium antagonists may play an important future role in renal hemodynamics related to their reversal of renal vasoconstrictors. Calcium antagonists are also capable of blocking intracellular calcium overload induc...

journal_title：Renal failure

authors： Neumayer HH,Gellert J,Luft FC

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Hypertension very often accompanies progression of chronic kidney disease (CKD) in children. A cross-sectional analysis of hypertension prevalence in dialyzed children in Poland was designed with a comparison with the data previously recorded 10 years earlier. METHODS:Two cohorts of children were analyzed: ...

journal_title：Renal failure

authors： Tkaczyk M,Stańczyk M,Miklaszewska M,Zachwieja K,Wierciński R,Stankiewicz R,Firszt-Adamczyk A,Zachwieja J,Borzęcka H,Zagożdżon I,Leszczyńska B,Medyńska A,Adamczyk P,Szczepańska M,Fendler W

更新日期：2017-11-01 00:00:00

abstract：:Albumin has been considered a "sacrificial plasma antioxidant" due to the high reactivity of the protein sulfhydryl groups with oxidants such as hydrogen peroxide (H2O2) and hypochlorous acid (HOCl). Based on its large quantity and high turnover. It is considered as one of the most important plasma antioxidants for pr...

journal_title：Renal failure

authors： Wratten ML,Sereni L,Tetta C

更新日期：2001-05-01 00:00:00

abstract：BACKGROUNDS/AIMS:Renal ischemia-reperfusion (IR) induces organ damage in remote organs. The aim of this study was to assess the role of leukocytes in the induction of liver damage after renal IR injury. METHODS:Inbred mice were subjected to either sham operation or bilateral renal IR injury (60 min ischemia followed b...

journal_title：Renal failure

authors： Khastar H,Kadkhodaee M,Sadeghipour HR,Seifi B,Hadjati J,Delavari F,Soleimani M

更新日期：2011-01-01 00:00:00

abstract：AIM:The aim of the present study was to investigate the value of the urine cell glycoprotein 1 (PC-1), aminopeptidase N (APN), N-acetyl-beta-D-glucosaminidase (NAGA), and dipeptidylpeptidase IV (DPP IV) in the evaluation of tubular damage in patients with primary glomerulonephritis, diabetic nephropathy, and lupus neph...

journal_title：Renal failure

authors： Mitic B,Lazarevic G,Vlahovic P,Rajic M,Stefanovic V

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Acute hyperammonemia caused by urea cycle disorder is a medical emergency for which immediate managements should be taken to minimize permanent brain damage. Among different enzyme defects, ornithine transcarbamylase deficiency (OTC) is one of the most common enzyme defect in urea cycle disorders. We utilize...

journal_title：Renal failure

authors： Chen CY,Chen YC,Fang JT,Huang CC

更新日期：2000-11-01 00:00:00

abstract：INTRODUCTION:Organic solvents are liquid substances commonly used in everyday life at home and in industrial workplaces. These solvents are found primarily in paint as thinner. Because other narcotics are hard to find, thinner is used as a narcotic especially among youngsters of low socioeconomic level. The aim of this...

journal_title：Renal failure

authors： Toros AB,Toros SZ,Aker F,Ersoz F,Derin A,Kesici B,Ozel L

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Diabetic nephropathy (DN) is a leading cause of diabetes-related morbidity and mortality. The aim of this study was to evaluate the relationship of AGT M235T and apoprotein E (APO E) gene polymorphism with DN in Turkish patients of Type 2 diabetes, and to compare genotype and allele distributions among DN pa...

journal_title：Renal failure

authors： Reis KA,Ebinç FA,Koç E,Demirci H,Erten Y,Güz G,Derici UB,Bali M,Söylemezoğlu O,Arınsoy T,Sindel S

更新日期：2011-01-01 00:00:00