The subjective sleep quality and heart rate variability in hemodialysis patients.


INTRODUCTION:Sleep disturbances and cardiovascular autonomic dysfunction are major complications of hemodialysis (HD). The goal of this study is to identify clinical, heart rate variability (HRV) or laboratory parameters that are independently associated with subjective sleep quality. PATIENT AND METHODS:Forty-six stable HD patients filled out sleep questionnaires - Pittsburgh sleep quality index (PSQI), Athens insomnia scale (AIS), and Epworth sleepiness scale (ESS). In addition, they received analyses of 5-minute HRV twice, in lying posture before and after HD. We also recruited 50 healthy subjects who received 5-min HRV. RESULTS:The patients with end-stage renal disease have a high rate of poor sleep quality according to PSQI, AIS, and ESS. The activities of total power (0-0.5 Hz), high-frequency power (HF, 0.15-0.40 Hz), low-frequency power (0.04-0.15 Hz), and very-low-frequency power (0.003-0.04 Hz) in HD patients are obviously lower than that in the healthy people. The poor sleepers (PSQI > 5) show lower heart rate, higher HF and variance before HD, but did not show a significant difference after HD. There is no significant difference between HRV and global score of AIS, but the insomnia group (AIS > 5) has higher BMI. These patients with sleepiness (ESS > 9) only reveal lower hemoglobin, although the global score of ESS reveals no significant relationship with HRV. CONCLUSION:HD patients have a high rate of poor sleep quality and autonomic dysfunction. Greater attention for the evaluation of sleep quality is needed for the better care of HD patients.


Ren Fail


Renal failure


Wei CY,Chung TC,Wu SC,Chung CF,Wu WP




Has Abstract


2011-01-01 00:00:00












  • A modified relief of unilateral ureteral obstruction model.

    abstract::Objectives: To improve the mouse model of relief for unilateral ureteral obstruction (RUUO) and explore the pathological process of renal fibrosis after the obstruction was relieved. Methods: C57BL/6 mice in model group were randomly divided into RUUO group, improved RUUO group, and UUO group. After leaving Unilateral...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Song J,Liu J,Luo J,Zhang Q,Xia Y,Shao Q,Sun C,Jiang C,Zhang M,Zhu W

    更新日期:2019-11-01 00:00:00

  • What has changed in the prevalence of hypertension in dialyzed children during the last decade?

    abstract:BACKGROUND:Hypertension very often accompanies progression of chronic kidney disease (CKD) in children. A cross-sectional analysis of hypertension prevalence in dialyzed children in Poland was designed with a comparison with the data previously recorded 10 years earlier. METHODS:Two cohorts of children were analyzed: ...

    journal_title:Renal failure

    pub_type: 杂志文章,多中心研究


    authors: Tkaczyk M,Stańczyk M,Miklaszewska M,Zachwieja K,Wierciński R,Stankiewicz R,Firszt-Adamczyk A,Zachwieja J,Borzęcka H,Zagożdżon I,Leszczyńska B,Medyńska A,Adamczyk P,Szczepańska M,Fendler W

    更新日期:2017-11-01 00:00:00

  • Primary disseminated form of Ewing sarcoma in association with hypercalcemia and acute renal failure.

    abstract::We present a case of an extremely rare form of Ewing sarcoma--primary disseminated, with fulminating course, severe hypercalcemia, extensive calcium deposition in parenchymatous organs, including kidneys, and acute renal failure as a clinical consequence. Correction of hypercalcemia was followed by prompt restoration ...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Lozance LA,Zafirovska KG,Bogdanovska SV,Zafirovski GJ

    更新日期:1994-01-01 00:00:00

  • Unusual clinic presentation of polyarteritis nodosa: involvement of axillary and brachial artery.

    abstract::Polyarteritis nodosa (PAN) is a necrotizing inflammatory vasculitis of small- and medium-sized muscular arteries. Multiple organs, especially the kidney, skin, peripheric nerves, striated muscles, and intestine, are affected. In this case report, a patient with renal and hepatic involvement and axillary and brachial a...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Kocyigit I,Koyuncu S,Mavili E,Unal A,Tokmak TT,Cilan H,Kavuncuoglu F,Oymak O,Utas C

    更新日期:2011-01-01 00:00:00

  • Indwelling hemodialysis catheterization by transthoracic way.

    abstract::Chronic kidney failure can be described as a chronic and progressive disfunction in metabolic-endocrine function and in adjustment of fluid-electrolyte balance of kidney, as a result of reducing of glomerular filtration value. Besides being a medical issue, chronic kidney failure affects social, economic, and psycholo...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Yildiz Z,Tort M,Çalik ES,Arslan Ü,Kaygin MA

    更新日期:2015-04-01 00:00:00

  • High mobility group box 1 and tumor growth factor β: useful biomarkers in pediatric patients receiving peritoneal dialysis.

    abstract:BACKGROUND:Peritonitis, the most important limitation of peritoneal dialysis (PD), could be detected by biomarkers in dialysate effluent, representing a noninvasive method to indirectly assess the peritoneum status. The aim of our study was to test high mobility group box 1 (HMGB1) in PD patients, evaluating its role a...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Chimenz R,Lacquaniti A,Colavita L,Chirico V,Fede C,Buemi M,Fede C

    更新日期:2016-10-01 00:00:00

  • Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication.

    abstract::Amidinotransferase (transamidinase, L-arginine: glycine amidinotransferase, EC is an enzyme that catalyses the first step in creatine synthesis primarily in the kidney and pancreas. The kidney is also the primary target organ for the toxic effect of mercury. Therefore, we studied the effect of acute uremic sy...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Nikolic J,Sokolovic D

    更新日期:2004-11-01 00:00:00

  • Development of new nephrons in adult kidneys following gentamicin-induced nephrotoxicity.

    abstract::Gentamicin-induced nephrotoxicity results in necrosis of proximal tubular epithelial cells. In mammals, the injured nephron can be repaired by migration and division of surviving cells. We examined this repair process in the fresh-water goldfish, Carassius auratus. Fish were given a single intraperitoneal injection of...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Reimschuessel R,Williams D

    更新日期:1995-03-01 00:00:00

  • Efficacy comparison of atorvastatin versus rosuvastatin on blood lipid and microinflammatory state in maintenance hemodialysis patients.

    abstract:INTRODUCTION:To investigate the effect of Atorvastatin (ATO) and Rosuvastatin (ROS) on blood lipid, high sensitivity CRP (hs-CRP), interleukin-6 (IL-6), albumin (ALB), prealbumin (PA), and transferring (TF) in maintenance hemodialysis (MHD) patients. METHODS:Eighty MHD patients were enrolled and divided into two group...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Tian J,Hou X,Hu L,Chen T,Wu K,Cai C,Bai X

    更新日期:2017-11-01 00:00:00

  • A novel rodent model of severe renal ischemia reperfusion injury.

    abstract::Renal ischemia reperfusion injury (IRI) is a major problem, currently without treatments in clinical use. This reflects the failure of animal models to mimic the severity of IRI observed in clinical practice. Most described models lack both the ability to inflict a permanent reduction in renal function and the sensiti...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Whalen H,Shiels P,Littlejohn M,Clancy M

    更新日期:2016-11-01 00:00:00

  • Renal cortical mitochondria are the source of oxygen free radicals enhanced by gentamicin.

    abstract::Rat renal cortical mitochondria were isolated from Wistar male rats weighing 80 to 120 g to investigate whether the source of oxygen free radicals was renal cortical mitochondria enhanced by gentamicin. In renal cortical mitochondria with or without the addition of gentamicin, DMSO, DFO, CAT, SOD, and MT1 were added s...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Yang CL,Du XH,Han YX

    更新日期:1995-01-01 00:00:00

  • Paraoxonase enzyme activity is enhanced by zinc supplementation in hemodialysis patients.

    abstract:BACKGROUND AND AIMS:Patients on maintenance hemodialysis (HD) face an increased risk of atherosclerosis, a crucial problem and the leading cause of cardiovascular morbidity and mortality. This study was designed to evaluate the effects of zinc supplementation on paraoxonase (PON) enzyme activity in patients on HD. MET...

    journal_title:Renal failure

    pub_type: 杂志文章,随机对照试验


    authors: Rahimi-Ardabili B,Argani H,Ghorbanihaghjo A,Rashtchizadeh N,Naghavi-Behzad M,Ghorashi S,Nezami N

    更新日期:2012-01-01 00:00:00

  • Evaluation of hemodialysis efficiency by an edema fluid model.

    abstract::The concentrations of urea, creatinine, and uric acid were measured in edema fluid and plasma during hemodialysis and 18 h after hemodialysis. The concentrations of these solutes in plasma were 15-17% lower than in the edema fluid after hemodialysis. Eighteen hours after hemodialysis, however, the concentrations in pl...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Shirai D,Kajimoto Y,Ochi S,Tanaka Y,Wada A,Yano F,Izumi M,Fujita Y,Nakahama H

    更新日期:1992-01-01 00:00:00

  • Defining peritoneal dialysis adequacy: Kt/Vurea revisited.

    abstract:BACKGROUND:Although adequate peritoneal dialysis is not well defined, Kt/Vurea has been used as an index, and various values have been proposed. However, conflicting evidence existed regarding the appropriateness of using Kt/Vurea to define dialysis adequacy and its optimal value. Therefore, the present study performed...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Zhe XW,Shan YS,Cheng L,Tian XK,Wang T

    更新日期:2007-01-01 00:00:00

  • Left ventricle ejection fraction may predict mortality in renal transplant patients.

    abstract:PURPOSE:Mortality is a major problem in renal transplant patients, and appropriate preoperative evaluation is very important. We retrospectively reviewed the left ventricle ejection fraction (LVEF) of renal transplant patients. MATERIAL AND METHODS:The clinical records of 1763 patients who had preoperative LVEF result...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Ozkul F,Kasim Arik M,Erbiş H,Akbaş A,Yilmaz VT,Barutcu A,Ali Osmanoğlu I,Kocak H

    更新日期:2016-11-01 00:00:00

  • Synergistic action of inflammation and lipid dysmetabolism on kidney damage in rats.

    abstract::In kidney disease, inflammation and lipid dysmetabolism are often associated together, however, the effect and mechanism of inflammatory mediators and lipid dysmetabolism on kidney damage is still unclear. In this study, Wistar rats were randomized into four groups: normal diet + saline (Group N), high-fat diet (HF)+ ...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Wang Z,Huang W,Li H,Tang L,Sun H,Liu Q,Zhang L

    更新日期:2018-11-01 00:00:00

  • Community-based study on elderly CKD subjects and the associated risk factors.

    abstract:OBJECTIVE:To investigate the prevalence and risk factors for chronic kidney disease (CKD) among community elderly population in Shanghai, China, in order to provide early diagnosis and treatment of CKD, and improve the quality of life for elderly people. METHODS:In all, 24,886 residents (≥65 years old) were selected f...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Huang YP,Zheng T,Zhang DH,Chen LY,Mao PJ

    更新日期:2016-11-01 00:00:00

  • Ozone therapy ameliorates tubulointerstitial inflammation by regulating TLR4 in adenine-induced CKD rats.

    abstract::Tubulointerstitium inflammation is a common pathway aggravating chronic kidney disease (CKD) progression and the mechanism is partly associated with excessive activation of toll-like receptor 4 (TLR4) in tubulointerstitium. Ozone therapy is demonstrated to alleviate inflammation in some experiments. The aim of this st...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Chen Z,Liu X,Yu G,Chen H,Wang L,Wang Z,Qiu T,Weng X

    更新日期:2016-06-01 00:00:00

  • Wider intraoperative glycemic fluctuation increases risk of acute kidney injury after pediatric cardiac surgery.

    abstract:OBJECTIVE:The association between poor intraoperative glycemic control and postoperative acute kidney injury (AKI) in adult cardiac surgery has been observed, but data in the pediatrics remain unknown. We performed a hypothesis that intraoperative hyperglycemia and/or wider glycemic fluctuation were associated with the...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Hu GH,Duan L,Jiang M,Zhang CL,Duan YY

    更新日期:2018-11-01 00:00:00

  • Factors related to pulse wave velocity and augmentation index in chronic hemodialysis patients.

    abstract:BACKGROUND:Augmentation index (AIx) and pulse wave velocity (PWV) are early markers of atherosclerotic vascular changes and also have been shown to be predictive of cardiovascular disease and total mortality. The aim of our study was to evaluate the relationship between PWV and AIx-HR75, which is the corrected form of ...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Celik G,Demirci MS,Tumuklu M,Ascı G,Sipahi S,Toz H,Bascı A,Ok E

    更新日期:2011-01-01 00:00:00

  • Inhibitory factors of serum opsonic activity in serum from patients with chronic renal failure.

    abstract::We investigated the mechanism of impaired serum opsonic activity in patients suffering from chronic renal failure (CRF). Prehemodialysis pooled serum from CRF patients was fractionated using Sephadex G-50 gel chromatography, and the effects of the obtained fractions on serum opsonic activity were examined using lumino...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Kikuchi T,Nigawara K,Sugawara K,Nakaji S,Abe T,Satoh H

    更新日期:1997-01-01 00:00:00

  • Resolving erythrocytosis and hypertension after open surgical extirpation of giant renal cyst measuring 30 cm: case report.

    abstract::The case of giant renal cyst measuring 30 cm, accompanied by abdominal swelling and erythrocytosis, is presented. A 45-year-old male presented with large abdominal mass, atrophic left kidney, hypertension, and erythrocytosis. The patient underwent multiple preoperative phlebotomies, open extirpation of the cyst, and n...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Pejcic T,Hadzi-Djokic J,Markovic B,Naumovic R

    更新日期:2011-01-01 00:00:00

  • Nighttime blood pressure fall in renal disease patients.

    abstract:OBJECTIVE:There are controversial reports in the prevalence of abnormal nighttime blood pressure fall in renal patients. It has been evaluated nocturnal BP in renal patients using 24 h blood pressure monitoring (ABPM) in comparison with nontreated control subjects either normotensives or hypertensives. DESIGN AND METH...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Robles NR,Cancho B,Ruiz-Calero R,Angulo E,Sanchez-Casado E

    更新日期:2003-09-01 00:00:00

  • Alkaline phosphatase is independently associated with renal function in normoalbuminuric type 1 diabetic patients.

    abstract::Nonalcoholic fatty liver disease (NAFLD) is associated with an increased prevalence of chronic kidney disease in patients with type 1 diabetes. The aim of this study was to explore the relationship between markers of NAFLD, namely concentrations of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alka...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Bulum T,Kolarić B,Duvnjak M,Duvnjak L

    更新日期:2014-04-01 00:00:00

  • Acute renal failure caused by nontraumatic rhabdomyolysis.

    abstract::Nontraumatic rhabdomyolysis may be associated with severe metabolic disturbances. In particular, previous literature has described a 8-20% incidence of acute renal failure in rhabdomyolysis. The aim of this study was to evaluate our experience on 11 patients with acute renal failure treated by high-efficiency daily he...

    journal_title:Renal failure

    pub_type: 临床试验,杂志文章


    authors: Tozzo C,Mazzarella V,Splendiani G,Casciani CU

    更新日期:1997-05-01 00:00:00

  • Significant benefits after renal transplantation in patients with chronic heart failure and chronic kidney disease.

    abstract:BACKGROUND:Chronic heart failure (CHF) and chronic kidney disease (CKD) are serious medical conditions with significant morbidity and mortality and often coexist. Because of perioperative risks in these patients, they may not be considered a candidate for renal transplantation (RTx). MATERIAL AND METHODS:We compare re...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Kute VB,Vanikar AV,Patel HV,Gumber MR,Shah PR,Engineer DP,Balwani MR,Gautam RS,Modi PR,Shah VR,Trivedi HL

    更新日期:2014-07-01 00:00:00

  • Renal dysfunctions in glomerulonephropathy with rapidly declined renal failure.

    abstract::Eight patients aged between 5 and 26 years developed rapid deterioration of renal function and became oliguric/anuric with duration ranging from 1 to 21 days. The initial functional assessment revealed severe degree of glomerular, tubular, and vascular dysfunctions. The magnitude of renal dysfunction was quantified an...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Futrakul N,Pochanugool C,Sitprija V,Singkhwa V,Futrakul P,Yenrudi S,Sensirivatana R,Watana D,Poshyachinda M

    更新日期:1996-07-01 00:00:00

  • Relation between urinary cytology abnormalities and cyclosporine A therapy in bone marrow transplant recipients.

    abstract::The aim of the study was to determine the relationship, if any, between abnormalities in urinary cytology and the administration of cyclosporine A in bone marrow transplant recipients. Specific attention was given to the presence of tubular cells with round inclusions (TCRI). Two bone marrow transplant recipient group...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Sucic M,Boban D,Markovic-Glamocak M,Bogdanic V,Nemet D,Labar B,Cvoriscec D,Plavsic F,Stoos-Veic T,Mrsic M

    更新日期:1998-07-01 00:00:00

  • Rhabdomyolysis and acute renal failure following cardioversion and cardiopulmonary resuscitation.

    abstract::A 39-year-old male suffered a myocardial infarction at work and cardiopulmonary resuscitation was initiated immediately. After 15 cardioversions, ventricular fibrillation converted to sinus rhythm. Rhabdomyolysis with a 100-fold increase of serum creatine kinase level and myoglobinuria with acute renal failure ensued,...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Hojs R,Sinkovic A,Hojs-Fabjan T

    更新日期:1995-11-01 00:00:00

  • Detection of mature macrophages in urinary sediments: clinical significance in predicting progressive renal disease.

    abstract::The ability to predict the rate of progression of renal parenchymal disease may help in its clinical management. We undertook characterization of urinary macrophages obtained from patients with various renal diseases paying special attention to the differentiation from non-progressive to progressive renal diseases. A ...

    journal_title:Renal failure

    pub_type: 杂志文章


    authors: Hotta O,Kitamura H,Taguma Y

    更新日期:1998-03-01 00:00:00