Role of glutathione for cisplatin nephrotoxicity in young and adult rats.

abstract：:Extensive ablation of renal mass in experimental animals leads to progressive glomerulosclerosis and chronic renal failure (CRF). Clinical studies are far from answering the question whether patients with reduced renal mass are at risk of developing progressive CRF. The aim of our study was to examine the morphologica...

journal_title：Renal failure

authors： Buccianti G,Lorenz M,Cresseri D,Bianchi ML,Valenti G,Cicchetti F,Francucci BM

更新日期：1993-01-01 00:00:00

abstract：:This article reviews our experience with 111 pediatric patients following open-heart surgery over 1-year period. Peritoneal dialysis was required in 34 of 111 children (30.6%). We randomly selected 33 patients who did not require peritoneal dialysis as control group. The indications of dialysis were oligoanuria and/or...

journal_title：Renal failure

authors： Baskin E,Gulleroglu KS,Saygili A,Aslamaci S,Varan B,Tokel K

更新日期：2010-01-01 00:00:00

abstract：:Psoriasis, being limited to the skin, is generally a chronic inflammatory disorder. Several glomerular diseases have been distinguished due to renal histological findings of psoriatic patients to date. The underlying pathogenetic mechanisms of these associations remain unclear because of the limited number of cases. W...

journal_title：Renal failure

authors： Ceri M,Kurultak I,Unverdi S,Altay M,Duranay M

更新日期：2010-06-01 00:00:00

abstract：:Renal involvement is an unusual but significant Behcet´s disease (BD) complication and AA amyloidosis appears to be the most common etiology. IL-6 is a pro-inflammatory cytokine with an important role in AA amyloidosis development. Tocilizumab (TCZ) is a humanized anti-IL-6 receptor antibody that has emerged as an eff...

journal_title：Renal failure

authors： Redondo-Pachón MD,Enríquez R,Sirvent AE,Andrada E,Noguera-Pons R,Millán I,Amorós F

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Sirolimus has been considered to be a non-nephrotoxic agent. It may delay graft function due to a potential hindrance of the recovery from acute tubular necrosis. It remains controversial as to whether the concomitant administration of sirolimus (SRL) with calcineurin inhibitors delays graft function in Asia...

journal_title：Renal failure

authors： Hsu HJ,Tian YC,Chen YC,Lai BC,Fang JT,Yang CW,Wu MS

更新日期：2008-01-01 00:00:00

abstract：:We previously described a method to measure GFR in conscious spontaneously voiding rats. This method circumvents the need for anesthesia and for bladder instrumentation. It's main principle is the correction of renal 125I-iothalamate clearance for incomplete urine collection by the ratio of plasma and renal clearance ...

journal_title：Renal failure

authors： de Vries PA,Navis G,de Jong PE,de Zeeuw D

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:There are few reports on the safety and efficacy of long-term treatment with statins in patients with chronic renal disease and hyperlipidemia. We evaluated these subjects treated with fluvastatin. METHODS:After a 4-week run-in period, a total of 80 patients with diabetic nephropathy or chronic glomerulonep...

journal_title：Renal failure

authors： Yasuda G,Kuji T,Hasegawa K,Ogawa N,Shimura G,Ando D,Umemura S

更新日期：2004-07-01 00:00:00

abstract：:More than 70% of acute renal failure in man is of circulatory nature and results from hypoxic injury to the kidney. Since intrarenal hemodynamic and metabolic events cannot be accurately assessed in human acute renal failure, various experimental models of renal hypoperfusion or complete interruption of renal blood su...

journal_title：Renal failure

authors： Mohaupt M,Kramer HJ

更新日期：1989-01-01 00:00:00

abstract：:Patients with end-stage renal disease, including those treated with peritoneal dialysis, have a high risk for death, particularly from cardiovascular causes. Plasma fatty acid (FA) composition is used as an indicator of disease risk, because its alteration has been related to metabolic disease and cardiovascular disea...

journal_title：Renal failure

authors： Yerlikaya FH,Mehmetoglu I,Kurban S,Tonbul Z

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Preimplantation biopsy provides a window on the state of the renal allograft. In this study, the prognostic value of frozen section preimplantation graft biopsy was estimated and compared to regularly processed formalin-fixed biopsy. MATERIALS AND METHODS:Seventy-four renal allograft recipients were studi...

journal_title：Renal failure

authors： Goumenos DS,Kalliakmani P,Tsamandas AC,Maroulis I,Savidaki E,Fokaefs E,Papachristou E,Karavias D,Vlachojannis JG

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:The optimal delivered dialysis dose has been of a great interest for the last three decades, though a clear cut point has not been reached yet. We aimed to evaluate the relationship between one-year mortality and the delivered dialysis dose, which was recommended by Kidney Disease Outcomes Quality Initiative...

journal_title：Renal failure

authors： Sahutoglu T,Kara E,Ahbap E,Sakaci T,Koc Y,Basturk T,Sevinc M,Akgol C,Ucar ZA,Ozdemir Kayalar A,Caglayan FB,Unsal A

更新日期：2016-09-01 00:00:00

abstract：:In kidney disease, inflammation and lipid dysmetabolism are often associated together, however, the effect and mechanism of inflammatory mediators and lipid dysmetabolism on kidney damage is still unclear. In this study, Wistar rats were randomized into four groups: normal diet + saline (Group N), high-fat diet (HF)+ ...

journal_title：Renal failure

authors： Wang Z,Huang W,Li H,Tang L,Sun H,Liu Q,Zhang L

更新日期：2018-11-01 00:00:00

abstract：:Secondary hyperparathyroidism is one of the most common complications of chronic renal failure (CRF). Its pathogenesis is multifactorial and still not completely understood. Pathological mechanism of hypocalcemia, hyperphosphatemia and calcitriol deficiency are basic characteristics of CRF and main reason for morpholo...

journal_title：Renal failure

authors： Jeren-Strujić B,Rozman B,Lambasa S,Jeren T,Marković M,Raos V

更新日期：2001-03-01 00:00:00

abstract：:The use of colistin in the treatment of multidrug-resistant Gram-negative bacterial infections is restricted due to nephrotoxicity. We investigated the effects of aged black garlic extract (ABGE) on colistin-induced kidney injury in rats. Rats were assigned to four groups. Normal saline was intraperitoneally and intra...

journal_title：Renal failure

authors： Lee TW,Bae E,Kim JH,Jang HN,Cho HS,Chang SH,Park DJ

更新日期：2019-11-01 00:00:00

abstract：AIM:Endoplasmic reticulum (ER) stress and unfolded protein response (UPR) are implicated in many fibrotic diseases, including renal fibrosis. Whether Ginsenoside-Rg1 (G-Rg1) could attenuate renal fibrosis via suppression of ER stress and UPR has not been reported. The aim of this study was to explore the effect of G-Rg...

journal_title：Renal failure

authors： Li SS,Ye JM,Deng ZY,Yu LX,Gu XX,Liu QF

更新日期：2015-06-01 00:00:00

abstract：:Envenomations by venomous lizards are rare. Monitor lizard bite-induced acute kidney injury (AKI) is a previously unreported complication in humans. A 55-year-old female was bitten on her right leg during farming activity by a monitor lizard (Varanus bengalensis). The patient experienced severe local pain and bleeding...

journal_title：Renal failure

authors： Vikrant S,Verma BS

更新日期：2014-04-01 00:00:00

abstract：:Abstract TGF-β1 plays an important role in the pathogenesis of chronic renal diseases. Although the specific mechanism is unknown, a major factor is the potent fibrogenic activity of TGF-β1 in the chronic progression of renal diseases. TGF-β1 closely correlates with renal fibrosis in cooperation with several fibrosis-...

journal_title：Renal failure

authors： Qi R,Li W,Yu S

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Arteriovenous fistulae (AVFs) may remain patent after kidney transplantation (KTx), contributing to maladaptive cardiac remodeling. The flow in AVFs is associated with the diameter of its vessels and thus with the AVF location. The main objective of this study is to assess the influence of AVF location and i...

journal_title：Renal failure

authors： Letachowicz K,Bardowska K,Królicki T,Kamińska D,Banasik M,Zajdel K,Mazanowska O,Madziarska K,Janczak D,Krajewska M

更新日期：2021-12-01 00:00:00

abstract：:The ability to predict the rate of progression of renal parenchymal disease may help in its clinical management. We undertook characterization of urinary macrophages obtained from patients with various renal diseases paying special attention to the differentiation from non-progressive to progressive renal diseases. A ...

journal_title：Renal failure

authors： Hotta O,Kitamura H,Taguma Y

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND/AIM:There is little information on the development of anemia in the early stages of chronic kidney disease. The aim of this study was to analyze the onset of renal anemia in a cohort of initially nonanemic chronic kidney disease patients followed up in nephrology clinics. METHODS:This epidemiological, prosp...

journal_title：Renal failure

authors： Portolés J,Castelao AM,Gorriz JL,Tato AM,de Alvaro F

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Previous studies have found significant stressors experienced by nurses working in hemodialysis units. The purpose of this study was to determine the burnout levels of hemodialysis nurses working in hemodialysis units and their relation with some sociodemographic variables. METHODS:The study was conducted b...

journal_title：Renal failure

authors： Kavurmacı M,Cantekin I,Tan M

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Influenza infection is a significant cause of morbidity and mortality in general population. Hemodialysis patients are considered at high risk of influenza infection given their altered immune status. Pandemic influenza virus is new for human beings, so it is hard to predict the response to infection or vacc...

journal_title：Renal failure

authors： Temiz G,Kasifoglu N,Kiris A,Ozturk S,Sahin G,Yalcin AU,Us T

更新日期：2010-07-01 00:00:00

abstract：AIM:To investigate the effects of lentivirus-mediated shRNA targeting collagen type I on the mesangial cells of rats and the feasibility of lentivirus-mediated shRNA delivery through renal parenchyma injection. METHODS:Anti-collagen type I shRNA lentiviral vector was constructed, and rat mesangial cells were transfect...

journal_title：Renal failure

authors： Zhou C,Shan Y,Zhao H,He P

更新日期：2011-01-01 00:00:00

abstract：:A newly identified cytokine, osteoprotegerin (OPG) appears to be involved in the regulation of bone remodeling. In vitro studies suggest that OPG, a soluble member of the TNF receptor family of proteins, inhibits osteoclastogenesis by interrupting the intercellular signaling between osteoblastic stromal cells and oste...

journal_title：Renal failure

authors： Crisafulli A,Romeo A,Floccari F,Aloisi E,Atteritano M,Cincotta M,Aloisi C,Pizzoleo MA,Ruello A,Artemisia A,Valenti A,Frisina N,Teti D,Buemi M

更新日期：2005-01-01 00:00:00

abstract：:Amidinotransferase (transamidinase, L-arginine: glycine amidinotransferase, EC 2.1.4.1) is an enzyme that catalyses the first step in creatine synthesis primarily in the kidney and pancreas. The kidney is also the primary target organ for the toxic effect of mercury. Therefore, we studied the effect of acute uremic sy...

journal_title：Renal failure

authors： Nikolic J,Sokolovic D

更新日期：2004-11-01 00:00:00

abstract：:Many Chinese like to drink alcohol soaked with creatures for promoting health. This study reports a 49-year-old male who presented with multiple focal neuropathies of the upper limbs, coagulopathy, erythematous swelling of the bilateral upper extremities and trunk with bullous skin lesions, and rhabdomyolysis associat...

journal_title：Renal failure

authors： Wang IK,Hsu SP,Chi CC,Lee KF,Lin PY,Chang HW,Chuang FR

更新日期：2004-01-01 00:00:00

abstract：:There are conflicting results in studies concerning the best marker for liver histopathological features of HCV infection in HD patients. We planned a prospective study to follow HCV viremia and laboratory parameters of HD patients and correlate these with clinic features and histopathological findings. We included 68...

journal_title：Renal failure

authors： Sezer S,Ozdemir BH,Arat Z,Turan M,Ozdemir NF,Haberal M

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:The thrombotic thrombocytopenic purpura (TTP) is a rare disorder with a high mortality rate if untreated or delayed therapy. Whether immediate diagnosis and promptly treated with plasma exchange can change the grave prognosis? METHOD:Retrospective analysis was performed on clinical characteristics and treat...

journal_title：Renal failure

authors： Yang CW,Chen YC,Dunn P,Chang MY,Fang JT,Huang CC

更新日期：2003-01-01 00:00:00

abstract：:Objective The objective of this study is to explore the efficacy and safety of mizoribine (MZR) in treating nephrotic syndrome patients afflicted with hepatitis B virus (HBV). Methods The present study included 36 nephrotic syndrome patients accompanied with HBV infection. A draft of MZR (150-200 mg/d), methylpredniso...

journal_title：Renal failure

authors： Liu J,Zhang K,Ji Y,Zhang W,Li W,Yong Q,Wang J,Sun J,Zhang H

更新日期：2016-06-01 00:00:00

abstract：:Although complete blood count is routinely ordered in most upper urinary tract infections (UTI), and information regarding the patient's platelet indices is made available without added cost, the relationship between platelet count and mean platelet volume (MPV) and specific platelet responses to different infectious ...

journal_title：Renal failure

authors： Catal F,Bavbek N,Bayrak O,Uz E,Isik B,Karabel M,Degirmencioglu H,Mete E,Akcay A

更新日期：2008-01-01 00:00:00