The combination of sirolimus and cyclosporine does not delay initial renal graft function recovery.

abstract：:Abstract TGF-β1 plays an important role in the pathogenesis of chronic renal diseases. Although the specific mechanism is unknown, a major factor is the potent fibrogenic activity of TGF-β1 in the chronic progression of renal diseases. TGF-β1 closely correlates with renal fibrosis in cooperation with several fibrosis-...

journal_title：Renal failure

authors： Qi R,Li W,Yu S

更新日期：2014-05-01 00:00:00

abstract：:Cardiovascular problems are a major cause of morbidity and mortality in patients with autosomal dominant polycystic kidney disease (ADPKD). Endothelial dysfunction (ED), which is an early manifestation of vascular injury, has been shown in patients with ADPKD. Statins have a beneficial effect in the reversal of ED. Th...

journal_title：Renal failure

authors： Namli S,Oflaz H,Turgut F,Alisir S,Tufan F,Ucar A,Mercanoglu F,Ecder T

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The optimal delivered dialysis dose has been of a great interest for the last three decades, though a clear cut point has not been reached yet. We aimed to evaluate the relationship between one-year mortality and the delivered dialysis dose, which was recommended by Kidney Disease Outcomes Quality Initiative...

journal_title：Renal failure

authors： Sahutoglu T,Kara E,Ahbap E,Sakaci T,Koc Y,Basturk T,Sevinc M,Akgol C,Ucar ZA,Ozdemir Kayalar A,Caglayan FB,Unsal A

更新日期：2016-09-01 00:00:00

abstract：:The effect of FK 506 pretreatment on renal ischemia and reperfusion (I/R) injury was investigated. Adult male rats were assigned to one of two groups (20 animals each). Group 1 (controls) received 0.5 mL saline while group 2 received FK 506 (0.3 mg/kg) intravenously 24 h prior to the induction of renal ischemia. After...

journal_title：Renal failure

authors： Van Thiel DH,Sakr M,Zetti G,McClain C

更新日期：1992-01-01 00:00:00

abstract：:Aldosterone is reported to promote fibrosis of multiple organs. Recent studies showed that Na+-H+ exchanger isoform 1 (NHE1) was involved in mineralocorticoid-induced tissue fibrosis. The present study examined the role of NHE1 in aldosterone-induced glomerulosclerosis in rats. SD male rats were subjected to 5/6 nephr...

journal_title：Renal failure

authors： Zhang M,Chen J,Liu S,You L,Lin S,Gu Y

更新日期：2009-01-01 00:00:00

abstract：:The use of colistin in the treatment of multidrug-resistant Gram-negative bacterial infections is restricted due to nephrotoxicity. We investigated the effects of aged black garlic extract (ABGE) on colistin-induced kidney injury in rats. Rats were assigned to four groups. Normal saline was intraperitoneally and intra...

journal_title：Renal failure

authors： Lee TW,Bae E,Kim JH,Jang HN,Cho HS,Chang SH,Park DJ

更新日期：2019-11-01 00:00:00

abstract：:Cyclosporine is used extensively in kidney transplantation and is a substrate for cytochrome P450 enzymes. The role of cytochrome p450 polymorphisms in kidney transplant outcome has not yet been fully elucidated. We investigate the clinical impact of single nucleotide polymorphisms in CYP3A4, CYP3A5, PPARα, and POR*28...

journal_title：Renal failure

authors： Traynor C,Conlon P Jr,Phelan PJ,O'Kelly P,Elens L,McCormack M,Cavalleri G,Comber H,van Schaik RH,Conlon PJ

更新日期：2015-05-01 00:00:00

abstract：:Anticoagulants are commonly used to prolong circuit life during continuous hemofiltration. However, a clear correlation between routinely performed blood coagulability tests and circuit life has not been demonstrated. This lack of correlation may derive from the limited ability of such tests to describe the likelihood...

journal_title：Renal failure

authors： Baldwin I,Tan HK,Bridge N,Bellomo R

更新日期：2000-05-01 00:00:00

abstract：INTRODUCTION:Sleep disturbances and cardiovascular autonomic dysfunction are major complications of hemodialysis (HD). The goal of this study is to identify clinical, heart rate variability (HRV) or laboratory parameters that are independently associated with subjective sleep quality. PATIENT AND METHODS:Forty-six sta...

journal_title：Renal failure

authors： Wei CY,Chung TC,Wu SC,Chung CF,Wu WP

更新日期：2011-01-01 00:00:00

abstract：:Cognitive dysfunction is a well-known complication of chronic renal failure that is evident in 30% of hemodialysis (HD) patients. However, the pathogenesis of this dysfunction is unknown. Left ventricular hypertrophy could develop in hypertensive HD patients without establishing normovolemia. Our aim was to evaluate t...

journal_title：Renal failure

authors： Dogukan A,Guler M,Yavuzkir MF,Tekatas A,Poyrazoglu OK,Aygen B,Gunal AI,Yoldas TK

更新日期：2009-01-01 00:00:00

abstract：:The risk of tuberculosis (TB) is significantly increased in chronic kidney disease (CKD). Data on TB in CKD in the UK are sparse; most information stems from countries with high background prevalence. The aim of this study was to estimate the incidence of TB in CKD patients in South East London and to describe the epi...

journal_title：Renal failure

authors： Ostermann M,Palchaudhuri P,Riding A,Begum P,Milburn HJ

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Peritonitis, the most important limitation of peritoneal dialysis (PD), could be detected by biomarkers in dialysate effluent, representing a noninvasive method to indirectly assess the peritoneum status. The aim of our study was to test high mobility group box 1 (HMGB1) in PD patients, evaluating its role a...

journal_title：Renal failure

authors： Chimenz R,Lacquaniti A,Colavita L,Chirico V,Fede C,Buemi M,Fede C

更新日期：2016-10-01 00:00:00

abstract：AIM:To establish the role of endothelin-1 and nitric oxide in the pathogenesis of hypertension in patients on chronic hemodialysis by correlating endothelin-1 and NO plasma concentrations to the level of arterial hypertension with respect to angiotensin-converting enzyme (ACE) inhibitor therapy. METHODS:We determined ...

journal_title：Renal failure

authors： Tomić M,Galesić K,Markota I

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Previous studies have found significant stressors experienced by nurses working in hemodialysis units. The purpose of this study was to determine the burnout levels of hemodialysis nurses working in hemodialysis units and their relation with some sociodemographic variables. METHODS:The study was conducted b...

journal_title：Renal failure

authors： Kavurmacı M,Cantekin I,Tan M

更新日期：2014-08-01 00:00:00

abstract：:The case records of 75 patients who had systemic lupus erythematosus (SLE) and renal involvement on renal histology were reviewed. There were 70 females and 5 males, with a ratio of 14:1. The majority of the patients were in their second and third decades of life. SLE nephritis was distinctly uncommon in patients belo...

journal_title：Renal failure

authors： Williams W,Shah D

更新日期：1990-01-01 00:00:00

abstract：:A 68-year-old male presented with acute myeloid leukemia, renal failure, hypokalemia, and enlarged kidneys on renal ultrasound. Renal biopsy revealed massive leukemic infiltration of the kidney. After systemic chemotherapy, the patient developed tumor lysis syndrome followed by a phase of proximal tubule dysfunction p...

journal_title：Renal failure

authors： Rüger W,Kruip MJ,Betjes MG

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The kidney is a major site for the inactivation, degradation, and clearance of a variety of peptide hormones. It has been shown that the uremia increases or decreases gastrointestinal system (GIS) hormones. Moreover, studies investigating the serum GIS hormones levels in chronic renal failure (CRF) were cond...

journal_title：Renal failure

authors： Borazan A,Cavdar Z,Saglam F

更新日期：2007-01-01 00:00:00

abstract：:Nonprescription medications are relatively safe, but not risk-free and can lead to serious adverse events, particularly if used contrary to directions or without attention to depicted warnings. The question arises whether the information presented on the product label is readable and comprehensible to the average lay ...

journal_title：Renal failure

authors： Trivedi H,Trivedi A,Hannan MF

更新日期：2014-04-01 00:00:00

abstract：:Recently we demonstrated the effect of fenoldopam on ischemia/reperfusion (I/R) induced NFkappaB mediated pro-inflammatory signal transduction. However, the effect of fenoldopam on I/R-induced apoptosis is not known. We utilized a rat model of acute ischemic nephropathy to test the hypothesis that fenoldopam attenuate...

journal_title：Renal failure

authors： Aravindan N,Cata JP,Dougherty PM,Shaw AD

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:Preimplantation biopsy provides a window on the state of the renal allograft. In this study, the prognostic value of frozen section preimplantation graft biopsy was estimated and compared to regularly processed formalin-fixed biopsy. MATERIALS AND METHODS:Seventy-four renal allograft recipients were studi...

journal_title：Renal failure

authors： Goumenos DS,Kalliakmani P,Tsamandas AC,Maroulis I,Savidaki E,Fokaefs E,Papachristou E,Karavias D,Vlachojannis JG

更新日期：2010-05-01 00:00:00

abstract：:Rhabdomyolysis ranges from an asymptomatic illness with elevated creatine kinase levels to a life-threatening condition associated with extreme elevations in creatine kinase, electrolyte imbalances, acute renal failure, and disseminated intravascular coagulation. The most common causes are crush injury, overexertion, ...

journal_title：Renal failure

authors： Celik H,Celik O,Guldiken S,Inal V,Puyan FO,Tugrul A

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Patients on long-term peritoneal dialysis develop progressive peritoneal fibrosis and loss of mesothelial layer. Regeneration of the mesothelium has been reported in the normal peritoneum but not the fibrotic peritoneum. Moreover, the origin of the regenerated mesothelial cells remains obscure. The aim of th...

journal_title：Renal failure

authors： Nishioka Y,Miyazaki M,Abe K,Furusu A,Harada T,Ozono Y,Taguchi T,Koji T,Kohno S

更新日期：2008-01-01 00:00:00

abstract：:We conducted a prospective study to determine the effect of intravenous low-dose iron administration in chronic hemodialysis patients treated with recombinant human erythropoietin (rHuEPO). Sixteen hemodialysis patients (8 males and 8 females; mean age 63.1+/-9.8 years) on maintenance rHuEPO therapy were included in t...

journal_title：Renal failure

authors： Harmankaya O,Eran A

更新日期：2002-03-01 00:00:00

abstract：:Freshly isolated rabbit proximal tubules (PT), confluent primary rabbit proximal tubule cultures (PTC) and LLC-PK1 cells were characterised. Brushborder enzyme activities were lower in PTC than in LLC-PK1: ratios were 0.026 for alkaline phosphatase (AP), 0.458 for alanine aminopeptidase (AAP) and 0.514 for gamma-gluta...

journal_title：Renal failure

authors： Toutain H,Courjault F,Vauclin-Jacques N,Morin JP

更新日期：1990-01-01 00:00:00

abstract：AIM:To assess the utility of neutrophil gelatinase-associated lipocalin (NGAL) in both urine and serum as a follow-up marker for the discrimination of prerenal acute kidney injury (AKI) from intrinsic AKI in critically ill pediatric patients with established AKI at the time of patient presentation. PATIENTS AND METHOD...

journal_title：Renal failure

authors： Polat M,Fidan K,Derinöz O,Gönen S,Söylemezoglu O

更新日期：2013-01-01 00:00:00

abstract：:Autosomal dominant polycystic disease (ADPKD) is one of the most common monogenic disorders, and globally is among the most common hereditary causes of end stage kidney disease. Until recently, the causes of this disease remained obscure. However, in the past decade there have been enormous advances in the understandi...

journal_title：Renal failure

authors： Kazancioglu R,Gursu M

更新日期：2015-05-01 00:00:00

abstract：:Nontraumatic rhabdomyolysis is an important but under-recognized cause of acute renal failure. In alcoholics, rhabdomyolysis most frequently develop following muscle necrosis during alcohol-induced coma, but has also been described rarely in those without prolonged coma or seizures. We describe a patient who developed...

journal_title：Renal failure

authors： Muthukumar T,Jha V,Sud A,Wanchoo A,Bambery P,Sakhuja V

更新日期：1999-09-01 00:00:00

abstract：:We previously described a method to measure GFR in conscious spontaneously voiding rats. This method circumvents the need for anesthesia and for bladder instrumentation. It's main principle is the correction of renal 125I-iothalamate clearance for incomplete urine collection by the ratio of plasma and renal clearance ...

journal_title：Renal failure

authors： de Vries PA,Navis G,de Jong PE,de Zeeuw D

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is associated with muscle excess fatigue and diminished maximal whole body oxygen consumption, which in part could be depended on poor muscle microcirculatory network. The aim of this study was to assume the influence of different stages of CKD on microcirculation vessels in func...

journal_title：Renal failure

authors： Flisiński M,Brymora A,Elminowska-Wenda G,Bogucka J,Walasik K,Stefańska A,Odrowaz-Sypniewska G,Manitius J

更新日期：2008-01-01 00:00:00

abstract：:Currently, obesity has reached an epidemic stage and represents a challenge for health authorities across the globe. Certainly, with emergence of obesity epidemic, we started to see an increase in the prevalence of chronic kidney disease (CKD) and nephrolithiasis. Interestingly, epidemiologic studies have shown that t...

journal_title：Renal failure

authors： Ahmed MH,Ahmed HT,Khalil AA

更新日期：2012-01-01 00:00:00