Acute ischemic renal failure: review of experimental studies on pathophysiology and potential protective interventions.

abstract：:Diabetic nephropathy (DN) is the most common cause of end-stage renal disease worldwide. The pathophysiologic mechanisms of diabetic nephropathy are incompletely understood but include overproduction of various growth factors and cytokines. Upregulation of vascular endothelial growth factor (VEGF) is a pathogenic even...

journal_title：Renal failure

authors： Patel L,Thaker A

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:The kidney is a major site for the inactivation, degradation, and clearance of a variety of peptide hormones. It has been shown that the uremia increases or decreases gastrointestinal system (GIS) hormones. Moreover, studies investigating the serum GIS hormones levels in chronic renal failure (CRF) were cond...

journal_title：Renal failure

authors： Borazan A,Cavdar Z,Saglam F

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Emerging evidence demonstrates that gut dysbiosis is implicated in the pathogenesis of chronic kidney disease (CKD) with underlying mechanisms involving mucosal and/or systematic immunity or metabolic disorders. However, the profile of gut microbiota in patients with CKD has not been completely explored. ME...

journal_title：Renal failure

authors： Zhao J,Ning X,Liu B,Dong R,Bai M,Sun S

更新日期：2021-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Glutathione S-transferases (GSTs) belong to a family of ubiquitous and multifunctional enzymes that work as one of the endogenous antioxidants in our body. This study was designed to look into the association of GST polymorphism with oxidative stress in both diabetic and nondiabetic chronic kid...

journal_title：Renal failure

authors： Datta SK,Kumar V,Pathak R,Tripathi AK,Ahmed RS,Kalra OP,Banerjee BD

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVES:To evaluate how chronic kidney disease (CKD) and diabetes mellitus (DM) influence in-hospital mortality in patients urgently admitted for acute heart failure (HF). METHODS:We used data from the Spanish "Minimum Basic Data Set" for 2006-2007 to evaluate clinical differences and crude mortality rates for pati...

journal_title：Renal failure

authors： de Miguel-Yanes JM,Méndez-Bailón M,Marco-Martínez J,Zapatero-Gaviria A,Barba-Martín R

更新日期：2014-11-01 00:00:00

abstract：:In kidney disease, inflammation and lipid dysmetabolism are often associated together, however, the effect and mechanism of inflammatory mediators and lipid dysmetabolism on kidney damage is still unclear. In this study, Wistar rats were randomized into four groups: normal diet + saline (Group N), high-fat diet (HF)+ ...

journal_title：Renal failure

authors： Wang Z,Huang W,Li H,Tang L,Sun H,Liu Q,Zhang L

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Long-term peritoneal exposure to high glucose in the peritoneal dialysis (PD) solution may potentiate the development of peritoneal fibrosis in PD patients. The most important factor leading to peritoneal fibrosis may be injury of human peritoneal mesothelial cells (HPMC). Little is known about senescence of...

journal_title：Renal failure

authors： Cao D,Zhang M,Jiang C,Xue L,Sun C

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The syndrome of rapid onset end-stage renal disease (SORO-ESRD) was first described in the journal Renal Failure in 2010. This is an acute precipitate unpredictable yet irreversible ESRD following acute kidney injury (AKI), as distinct from "classic" ESRD where chronic kidney disease (CKD)-ESRD progression w...

journal_title：Renal failure

authors： Onuigbo M,Agbasi N

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Sirolimus has been considered to be a non-nephrotoxic agent. It may delay graft function due to a potential hindrance of the recovery from acute tubular necrosis. It remains controversial as to whether the concomitant administration of sirolimus (SRL) with calcineurin inhibitors delays graft function in Asia...

journal_title：Renal failure

authors： Hsu HJ,Tian YC,Chen YC,Lai BC,Fang JT,Yang CW,Wu MS

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The kidney is one of the prior damaged organs subjected to severe infection and sepsis shock. Our previous studies have shown that the normal mesenteric lymph (NML) obtained from healthy dogs could alleviate multiple organ injuries following endotoxic shock. In the current study, we further investigated the ...

journal_title：Renal failure

authors： Zhao ZG,Zhang LM,Song W,Du HB,Cui H,Niu CY

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:The optimal delivered dialysis dose has been of a great interest for the last three decades, though a clear cut point has not been reached yet. We aimed to evaluate the relationship between one-year mortality and the delivered dialysis dose, which was recommended by Kidney Disease Outcomes Quality Initiative...

journal_title：Renal failure

authors： Sahutoglu T,Kara E,Ahbap E,Sakaci T,Koc Y,Basturk T,Sevinc M,Akgol C,Ucar ZA,Ozdemir Kayalar A,Caglayan FB,Unsal A

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Despite the widespread availability of dialytic and intensive care unit technology, the probability of early mortality in critically ill patients with acute renal failure (ARF) is still high, and the evaluation of the patients' prognosis has been difficult. The Acute Physiology and Chronic Health Evaluation ...

journal_title：Renal failure

authors： Chen YC,Hsu HH,Kao KC,Fang JT,Huang CC

更新日期：2001-01-01 00:00:00

abstract：:Autosomal dominant polycystic disease (ADPKD) is one of the most common monogenic disorders, and globally is among the most common hereditary causes of end stage kidney disease. Until recently, the causes of this disease remained obscure. However, in the past decade there have been enormous advances in the understandi...

journal_title：Renal failure

authors： Kazancioglu R,Gursu M

更新日期：2015-05-01 00:00:00

abstract：:Granulomatous interstitial nephritis (GIN) is a rare disease. Contributing factors such as drugs, sarcoidosis, infections, and paraproteinemia have been reported, and when no obvious contributing factors can be identified, the disease is classified as idiopathic GIN. We managed a patient with idiopathic GIN with an un...

journal_title：Renal failure

authors： Kim SJ,Hee Sung S

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Sleep disturbances and cardiovascular autonomic dysfunction are major complications of hemodialysis (HD). The goal of this study is to identify clinical, heart rate variability (HRV) or laboratory parameters that are independently associated with subjective sleep quality. PATIENT AND METHODS:Forty-six sta...

journal_title：Renal failure

authors： Wei CY,Chung TC,Wu SC,Chung CF,Wu WP

更新日期：2011-01-01 00:00:00

abstract：:Nontraumatic rhabdomyolysis is an important but under-recognized cause of acute renal failure. In alcoholics, rhabdomyolysis most frequently develop following muscle necrosis during alcohol-induced coma, but has also been described rarely in those without prolonged coma or seizures. We describe a patient who developed...

journal_title：Renal failure

authors： Muthukumar T,Jha V,Sud A,Wanchoo A,Bambery P,Sakhuja V

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:We aimed to evaluate whether serum apelin could reflect the nutritional status of children on dialysis. METHODS:Twelve patients on peritoneal dialysis (PD) and 20 patients on hemodialysis (HD) were enrolled. Patients received individualized diet for six months. Anthropometric and laboratory indices were mea...

journal_title：Renal failure

authors： Yavuz S,Cetinkaya S,Anarat A,Bayazıt AK

更新日期：2014-09-01 00:00:00

abstract：:We conducted a prospective study to determine the effect of intravenous low-dose iron administration in chronic hemodialysis patients treated with recombinant human erythropoietin (rHuEPO). Sixteen hemodialysis patients (8 males and 8 females; mean age 63.1+/-9.8 years) on maintenance rHuEPO therapy were included in t...

journal_title：Renal failure

authors： Harmankaya O,Eran A

更新日期：2002-03-01 00:00:00

abstract：:The hallmark of the professional is continued development and expanded expertise based on acquisition of new knowledge and refinement of clinical skills. Medical knowledge acquisition is a key component of professional development for fellows in training as well as practicing physicians. New medical knowledge may be a...

journal_title：Renal failure

authors： Mahan JD,Ferris ME

更新日期：2010-01-01 00:00:00

abstract：:This study was designed to investigate whether the treatment with the N-acetyl-L-cysteine prior to the administration of chemotherapy drug would prevent from nephrotoxicity and the loss of reproductive performance induced from chemotherapy treatment. Female rats were divided into five equal groups of six each: 1/contr...

journal_title：Renal failure

authors： Helal MA

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:Dyslipidemia is one of the onset and risk factors of chronic kidney disease and renal function drop is seen in lipoprotein abnormal animal models. However, the detailed molecular mechanism of renal lipotoxicity has not been clarified. Therefore, the present study aimed to investigate the influence of chole...

journal_title：Renal failure

authors： Honzumi S,Takeuchi M,Kurihara M,Fujiyoshi M,Uchida M,Watanabe K,Suzuki T,Ishii I

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:To investigate the anti proteinuric effect of pentoxifylline in diabetic patients, we prospectively studied in 25 hypertensive type 2 diabetic patients with persistent microalbuminuria and normal renal function the impact of combining pentoxifylline with an angiotensin converting enzyme inhibitor, lisinopril,...

journal_title：Renal failure

authors： Harmankaya O,Seber S,Yilmaz M

更新日期：2003-05-01 00:00:00

abstract：:Studies were performed to reexamine the response of erythropoietin (Epo) production to acute hypoxic stimuli in patients with end-stage renal disease (ESRD). In the absence of acute bleeding or hypoxia, the serum Epo level in ESRD was similar to that of normal subjects despite severe anemia. In 11 dialysis patients wi...

journal_title：Renal failure

authors： Kato A,Hishida A,Kumagai H,Furuya R,Nakajima T,Honda N

更新日期：1994-01-01 00:00:00

abstract：:We investigated the mechanism of impaired serum opsonic activity in patients suffering from chronic renal failure (CRF). Prehemodialysis pooled serum from CRF patients was fractionated using Sephadex G-50 gel chromatography, and the effects of the obtained fractions on serum opsonic activity were examined using lumino...

journal_title：Renal failure

authors： Kikuchi T,Nigawara K,Sugawara K,Nakaji S,Abe T,Satoh H

更新日期：1997-01-01 00:00:00

abstract：:The case of giant renal cyst measuring 30 cm, accompanied by abdominal swelling and erythrocytosis, is presented. A 45-year-old male presented with large abdominal mass, atrophic left kidney, hypertension, and erythrocytosis. The patient underwent multiple preoperative phlebotomies, open extirpation of the cyst, and n...

journal_title：Renal failure

authors： Pejcic T,Hadzi-Djokic J,Markovic B,Naumovic R

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of urokinase-type plasminogen activator (uPA) on mesangial matrix in the kidney of diabetic rats and its related mechanisms. METHODS:Diabetic Sprague-Dawley (SD) rats induced by intraperitoneal injection of streptozotocin (STZ) were randomly and evenly divided into two groups: DM + ...

journal_title：Renal failure

authors： Cheng H,Chen C,Wang S

更新日期：2014-09-01 00:00:00

abstract：:Acute renal failure (ARF) is a frequent complication in hospitalized patients and is strongly related to increase in mortality. In order to analyze the clinical outcome and the prognostic factors in hospital-acquired ARF, a prospective study was performed. Data from 200 patients with established ARF during the period ...

journal_title：Renal failure

authors： Barretti P,Soares VA

更新日期：1997-03-01 00:00:00

abstract：:Ciprofloxacin has been associated with several side effects including interstitial nephritis and hemolytic anemia. The combination of both side effects is extremely rare. In this report, we describe a case of ciprofloxacin-induced interstitial nephritis and autoimmune hemolytic anemia. Hemolytic anemia improved after ...

journal_title：Renal failure

authors： Lim S,Alam MG

更新日期：2003-07-01 00:00:00

abstract：:Iron accumulates within proximal tubular lysosomes in several models of renal disease and may play a role in the progression of proteinuric chronic renal disease by the generation of reactive oxygen species. In this study, tubular iron was examined at an ultrastructural level by energy dispersive x-ray spectrometry in...

journal_title：Renal failure

authors： Nankivell BJ,Tay YC,Boadle RA,Harris DC

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:In order to evaluate the clinical and pathological characteristics of diuretics associated acute kidney injury (AKI) and its management. METHODS:We performed a retrospective study including 131 cases that diagnosed as diuretics associated AKI from 1 January 1999 to 1 January 2010 in Ruijin Hospital affiliate...

journal_title：Renal failure

authors： Wu X,Zhang W,Ren H,Chen X,Xie J,Chen N

更新日期：2014-08-01 00:00:00