Abstract:
:Extensive ablation of renal mass in experimental animals leads to progressive glomerulosclerosis and chronic renal failure (CRF). Clinical studies are far from answering the question whether patients with reduced renal mass are at risk of developing progressive CRF. The aim of our study was to examine the morphological and functional aspects of the remnant kidney in a group of patients who underwent unilateral nephrectomy for renal tuberculosis: 313 patients (161 M, 152 F) mean age 57.2 +/- 10.7, were examined after a period ranging from 13.56 to 591.2 months. All patients were on ad libitum diet. Hypertension was found in 34.19% of the patients; SBP was 155.29 +/- 19.9 mmHg and DBP was 92.74 +/- 13.07 mmHg. Estimation of renal size performed by ultrasound scanner gave the following results: length 116.78 +/- 8.99 mm; width 58.24 +/- 7.21 mm; thickness 17.88 +/- 1.96 mm. Kidney function assessed by serum creatinine levels showed a mean level of 1.28 +/- 0.53 mg%. Forty-two patients (13.41%) had serum levels > 1.5 mg% but 18 of them had nonconcomitant systemic or renal involvement. Microalbuminuria determined by RIA assay was found in 50.5% of the patients. In our group of patients renal functional impairment was low and hyperfiltration expressed as microalbuminuria does not appear to be a primary factor in the progression of renal failure.
journal_name
Ren Failjournal_title
Renal failureauthors
Buccianti G,Lorenz M,Cresseri D,Bianchi ML,Valenti G,Cicchetti F,Francucci BMdoi
10.3109/08860229309054954subject
Has Abstractpub_date
1993-01-01 00:00:00pages
415-20issue
3eissn
0886-022Xissn
1525-6049journal_volume
15pub_type
杂志文章相关文献
RENAL FAILURE文献大全abstract::Postpartum acute kidney injury (PPAKI) constitutes an important cause of obstetric AKI. It is associated with high maternal and fetal mortality in developing nations. The aim of this study is to survey the etiology and outcomes of PPAKI in a tertiary care Indian hospital. Ninety-nine patients, without prior comorbidit...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2016.1164015
更新日期:2016-07-01 00:00:00
abstract::Controlling blood pressure in hemodialysis patients is crucial but not always easy. The most common blood pressure measurement method is peri-dialysis measurement, but due to interdialytic blood pressure fluctuations, we are unsure if it is the proper way for evaluating blood pressure. Some studies have shown the supe...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2014.883933
更新日期:2014-06-01 00:00:00
abstract::This study was designed to evaluate the seroprevalence of hepatitis G virus (HGV) infection, its impact, and its relationship with other hepatotropic viruses among chronic renal failure patients undergoing hemodialysis at the Lok Nayak Hospital, New Delhi. The study group consisted of 100 consecutive cases of patients...
journal_title:Renal failure
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::The risk of tuberculosis (TB) is significantly increased in chronic kidney disease (CKD). Data on TB in CKD in the UK are sparse; most information stems from countries with high background prevalence. The aim of this study was to estimate the incidence of TB in CKD patients in South East London and to describe the epi...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2015.1128290
更新日期:2016-01-01 00:00:00
abstract::Envenomations by venomous lizards are rare. Monitor lizard bite-induced acute kidney injury (AKI) is a previously unreported complication in humans. A 55-year-old female was bitten on her right leg during farming activity by a monitor lizard (Varanus bengalensis). The patient experienced severe local pain and bleeding...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2013.868223
更新日期:2014-04-01 00:00:00
abstract::Left ventricular hypertrophy (LVH) is a common abnormality in hemodialysis (HD) patients. Mitochondrial dysfunction contributes to the progression of LVH. As an inner mitochondrial membrane structural protein, mitofilin plays a key role in maintaining mitochondrial structure and function. The aim of this study was to ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/0886022X.2018.1456455
更新日期:2018-11-01 00:00:00
abstract:RATIONAL:The inhibition of renin-angiotensin-aldosterone system (RAAS) is a major strategy for slowing the progression of chronic kidney disease (CKD). The utility of anti-RAAS agents in patients with congenital or acquired solitary kidney is still controversial. OBJECTIVE:A systematic literature review was conducted....
journal_title:Renal failure
pub_type: 杂志文章,评审
doi:10.1080/0886022X.2017.1361840
更新日期:2017-11-01 00:00:00
abstract::The proximal convoluted tubule (PCT) is the major target for injury in gentamicin nephrotoxicity but the necrosis is often patchy and focal. The PCT is structurally, functionally, and metabolically heterogeneous, and the possibility of differential vulnerability to gentamicin-induced necrosis based on this heterogenei...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860229009087122
更新日期:1990-01-01 00:00:00
abstract::Antenatal hydronephrosis (AHN), defined as dilatation of renal pelvis and/or calyces, is the most frequently detected antenatal abnormality. However, postnatal management of AHN is controversial. The purpose of this study was to describe the clinical outcomes of infants with AHN and to contribute to the definition of ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2012.676492
更新日期:2012-01-01 00:00:00
abstract::Cold preservation has greatly facilitated the use of cadaveric kidneys for renal transplantation, but, clearly, damage occurs during both the preservation episode and the reperfusion phase (following transplantation). The aims of this study were twofold: to develop an in vivo model that was capable of evaluating renal...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/08860220701813327
更新日期:2008-01-01 00:00:00
abstract::Many Chinese like to drink alcohol soaked with creatures for promoting health. This study reports a 49-year-old male who presented with multiple focal neuropathies of the upper limbs, coagulopathy, erythematous swelling of the bilateral upper extremities and trunk with bullous skin lesions, and rhabdomyolysis associat...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-120028562
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:The quality of life in patients undergoing hemodialysis is significantly disturbed. There are data that hemodiafiltration (HDF) may be more effective than conventional hemodialysis in the removal of uremic toxins and may reduce frequency and severity of intradialytic and postdialysis adverse symptoms in pati...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2012.684555
更新日期:2012-01-01 00:00:00
abstract::The concentrations of urea, creatinine, and uric acid were measured in edema fluid and plasma during hemodialysis and 18 h after hemodialysis. The concentrations of these solutes in plasma were 15-17% lower than in the edema fluid after hemodialysis. Eighteen hours after hemodialysis, however, the concentrations in pl...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860229209039118
更新日期:1992-01-01 00:00:00
abstract::Pentoxifylline (PTX) has been reported to inhibit TNF-alpha production and prevent several types of acute renal failure. This study was undertaken to determine the effect of PTX on the cisplatin-induced acute renal failure in rabbits. Rabbits received a single injection of cisplatin (5 mg/kg, i.p.) with or without PTX...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-120026026
更新日期:2003-11-01 00:00:00
abstract:BACKGROUND:The kidney is one of the prior damaged organs subjected to severe infection and sepsis shock. Our previous studies have shown that the normal mesenteric lymph (NML) obtained from healthy dogs could alleviate multiple organ injuries following endotoxic shock. In the current study, we further investigated the ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2014.938585
更新日期:2014-09-01 00:00:00
abstract::Aquaporin-2 protein levels can be detected in the urine of normal of subjects if measured after fluid deprivation. By contrast, in patients with nephrogenic diabetes insipidus caused by mutations in the aquaporin-2 gene, urine aquaporin-2 protein excretion cannot be detected. We propose that properly standardized meas...
journal_title:Renal failure
pub_type: 杂志文章,评审
doi:10.3109/08860229909085095
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND:Acute hyperammonemia caused by urea cycle disorder is a medical emergency for which immediate managements should be taken to minimize permanent brain damage. Among different enzyme defects, ornithine transcarbamylase deficiency (OTC) is one of the most common enzyme defect in urea cycle disorders. We utilize...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-100101968
更新日期:2000-11-01 00:00:00
abstract:INTRODUCTION:Dyslipidemia is one of the onset and risk factors of chronic kidney disease and renal function drop is seen in lipoprotein abnormal animal models. However, the detailed molecular mechanism of renal lipotoxicity has not been clarified. Therefore, the present study aimed to investigate the influence of chole...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/0886022X.2017.1419974
更新日期:2018-11-01 00:00:00
abstract::This study was designed to investigate whether the treatment with the N-acetyl-L-cysteine prior to the administration of chemotherapy drug would prevent from nephrotoxicity and the loss of reproductive performance induced from chemotherapy treatment. Female rats were divided into five equal groups of six each: 1/contr...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2015.1127742
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:To investigate the anti proteinuric effect of pentoxifylline in diabetic patients, we prospectively studied in 25 hypertensive type 2 diabetic patients with persistent microalbuminuria and normal renal function the impact of combining pentoxifylline with an angiotensin converting enzyme inhibitor, lisinopril,...
journal_title:Renal failure
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1081/jdi-120021159
更新日期:2003-05-01 00:00:00
abstract::Increasing evidence suggests that circulating aldosterone per se contributes directly to renal and cardiovascular diseases. We sought to evaluate the effects of a three-month treatment with 25 mg spironolactone, an aldosterone receptor antagonist, on nephron function in 20 type II diabetic patients with persistent mic...
journal_title:Renal failure
pub_type: 临床试验,杂志文章
doi:10.1080/08860220802389342
更新日期:2008-01-01 00:00:00
abstract::Amidinotransferase (transamidinase, L-arginine: glycine amidinotransferase, EC 2.1.4.1) is an enzyme that catalyses the first step in creatine synthesis primarily in the kidney and pancreas. The kidney is also the primary target organ for the toxic effect of mercury. Therefore, we studied the effect of acute uremic sy...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-200037149
更新日期:2004-11-01 00:00:00
abstract:UNLABELLED:Intensity of dialysis dose in acute kidney injury (AKI) might benefit critically ill patients. The aim of this study was to evaluate the effect of intermittent hemodialysis (IHD) dose on mortality in patients with AKI. METHODS:Prospective observational study was performed on AKI patients treated with IHD. T...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2012.697444
更新日期:2012-01-01 00:00:00
abstract::There is limited information on the incidence of acute kidney injury (AKI) in patients with traumatic brain injury (TBI) although AKI may contribute to morbidity and mortality. We investigated the incidence of AKI in patients with moderate and severe TBI and the association of AKI with risk factors and outcomes in the...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2010.510234
更新日期:2010-01-01 00:00:00
abstract::Several studies have shown that hepatocyte growth factor (HGF) ameliorates chronic renal failure, but its mechanism of action is unclear. This study was designed to test the delivery of HGF in the PCI-neo vector, using the 5/6 nephrectomized rat as a model for chronic renal failure, and to confirm that this protective...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2013.867797
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Psychological problems such as depression and anxiety are common in hemodialysis patients. In several studies, exercise programs were effective in relieving depression or anxiety in these patients, although not all agree. PURPOSE:In this study, we evaluated the effects of an exercise program on exercise cap...
journal_title:Renal failure
pub_type: 临床试验,杂志文章
doi:10.1081/jdi-120005367
更新日期:2002-05-01 00:00:00
abstract::Aims: The aim was to determine whether anti-neutrophil cytoplasmic antibody (ANCA)-positive serology in patients with lupus nephritis (LN) is associated with different clinicopathologic features and outcomes.Methods: In our retrospective analysis, 283 patients were enrolled between 2013 and 2018. Thirty-six patients w...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/0886022X.2020.1735416
更新日期:2020-11-01 00:00:00
abstract::Ten-Eleven Translocation (TET) proteins oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytonsie (5hmC). Our recent work found a decline in global 5hmC level in mouse kidney insulted by ischemia reperfusion (IR). However, the genomic distribution of 5hmC in mouse kidney and its relationship with gene expression remai...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2016.1172973
更新日期:2016-07-01 00:00:00
abstract::Uncertainty of measurement is the numeric expression of the errors associated with all measurements taken in clinical laboratories. Serum creatinine concentration is the most common diagnostic marker for acute kidney injury. The goal of this study was to determine the effect of the uncertainty of measurement of serum ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2015.1117925
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Hemodialysis (HD) patients often experience cardiovascular events, that might be related to altered calcium-phosphate metabolism, dyslipidemia, and chronic inflammation in addition to hypertension. Sevelamer, a non-calcium-containing phosphate binder, may improve the lipid profile of HD patients. However, th...
journal_title:Renal failure
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00