Biological effects of lentivirus-mediated shRNA targeting collagen type I on the mesangial cells of rats.

abstract：UNLABELLED:Contrast-induced nephropathy (CIN) is the third leading cause of acute kidney injury (AKI) in hospitalized patients. Diabetes mellitus remains a consistent independent predictor of contrast nephropathy. AIM:To determine frequency and predictors of contrast-induced nephropathy after cardiac catheterization i...

journal_title：Renal failure

authors： Sany D,Refaat H,Elshahawy Y,Mohab A,Ezzat H

更新日期：2014-03-01 00:00:00

abstract：:Hypertonic glycerol injection is one of the most frequently used models of experimental acute renal failure. Late structural changes such as interstitial fibrosis in the renal cortex and tubular atrophy have been detected after severe acute tubular necrosis (ATN). The aim of this study was to investigate the expressio...

journal_title：Renal failure

authors： de Jesus Soares T,Costa RS,de Mattos Coelho R,Alves da Silva CG,Coimbra TM

更新日期：2005-01-01 00:00:00

abstract：INTRODUCTION:Dyslipidemia is one of the onset and risk factors of chronic kidney disease and renal function drop is seen in lipoprotein abnormal animal models. However, the detailed molecular mechanism of renal lipotoxicity has not been clarified. Therefore, the present study aimed to investigate the influence of chole...

journal_title：Renal failure

authors： Honzumi S,Takeuchi M,Kurihara M,Fujiyoshi M,Uchida M,Watanabe K,Suzuki T,Ishii I

更新日期：2018-11-01 00:00:00

abstract：:Valacyclovir induced neurotoxicity is a life-threatening complication, usually starting 24-48 h after drug-peak serum concentrations. The elderly with impaired renal function seem to be the most susceptible group to valacyclovir neurotoxicity. Although hemodialysis is considered the best method for rapid drug removal,...

journal_title：Renal failure

authors： Pipili C,Pantelias K,Deda E,Tsiamalos P,Kostis E,Grapsa E

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To investigate the prevalence and risk factors for chronic kidney disease (CKD) among community elderly population in Shanghai, China, in order to provide early diagnosis and treatment of CKD, and improve the quality of life for elderly people. METHODS:In all, 24,886 residents (≥65 years old) were selected f...

journal_title：Renal failure

authors： Huang YP,Zheng T,Zhang DH,Chen LY,Mao PJ

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Transforming growth factor-beta1 (TGF-beta1), the major fibrogenic growth factor, is implicated in the pathogenesis of renal scarring in experimental and clinical nephropathies as well as in chronic allograft nephropathy. In this study we examined the pattern of changes of TGF-beta1 excretion in the urine an...

journal_title：Renal failure

authors： Goumenos DS,Tsakas S,Karavias D,Savidaki I,Karatzas T,Vlachojannis JG

更新日期：2003-07-01 00:00:00

abstract：:A positive association between inflammation and chronic kidney disease (CKD) has been reported but the impact of hypertension on this relation remains unclear. The aim of this study is to investigate the association of various inflammation markers with risk of CKD in hypertensive patients. 387 hypertensive patients (m...

journal_title：Renal failure

authors： Xu TY,Zhang Y,Li Y,Zhu DL,Gao PJ

更新日期：2014-06-01 00:00:00

abstract：:Tubulointerstitium inflammation is a common pathway aggravating chronic kidney disease (CKD) progression and the mechanism is partly associated with excessive activation of toll-like receptor 4 (TLR4) in tubulointerstitium. Ozone therapy is demonstrated to alleviate inflammation in some experiments. The aim of this st...

journal_title：Renal failure

authors： Chen Z,Liu X,Yu G,Chen H,Wang L,Wang Z,Qiu T,Weng X

更新日期：2016-06-01 00:00:00

abstract：:Several studies have shown that hepatocyte growth factor (HGF) ameliorates chronic renal failure, but its mechanism of action is unclear. This study was designed to test the delivery of HGF in the PCI-neo vector, using the 5/6 nephrectomized rat as a model for chronic renal failure, and to confirm that this protective...

journal_title：Renal failure

authors： Wang HY,Yang LZ,Gu CM,Chen Y,Zhao Y,Zhao D,Li TS,Cui MJ

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is associated with muscle excess fatigue and diminished maximal whole body oxygen consumption, which in part could be depended on poor muscle microcirculatory network. The aim of this study was to assume the influence of different stages of CKD on microcirculation vessels in func...

journal_title：Renal failure

authors： Flisiński M,Brymora A,Elminowska-Wenda G,Bogucka J,Walasik K,Stefańska A,Odrowaz-Sypniewska G,Manitius J

更新日期：2008-01-01 00:00:00

abstract：:The Hakka are a sub-ethnicity with unique diet customs in South China. This study investigated hyperphosphatemia in hemodialysis patients in relation to the current Hakka dietary customs and explored health education patterns for hyperphosphatemia control. Two continuous cross-sectional surveys were conducted among th...

journal_title：Renal failure

authors： Chen Y,Li Z,Liang X,Zhang M,Zhang Y,Xu L,Zhong L,Shi W

更新日期：2015-01-01 00:00:00

abstract：UNLABELLED:Cytomegalovirus (CMV) disease is an important complication and an independent risk factor for acute rejection and recipient morbidity-mortality. The aim of this study was to review the results of CMV disease in renal transplant recipients. METHOD:We have retrospectively analyzed CMV disease in 120 renal tra...

journal_title：Renal failure

authors： Cavdar C,Celtik A,Saglam F,Sifil A,Atila K,Celik A,Tosun P,Olmuscelik O,Bora S,Gulay H,Camsari T

更新日期：2008-01-01 00:00:00

abstract：:This study was aimed to investigate the therapeutic potential of coenzyme Q10 and its combination with sitagliptin in experimentally induced diabetic nephropathy. The diabetic rats were treated with coenzyme Q10 or sitagliptin and their concomitant administration. Various parameters of renal function like serum creati...

journal_title：Renal failure

authors： Maheshwari R,Balaraman R,Sen AK,Shukla D,Seth A

更新日期：2017-11-01 00:00:00

abstract：:While the fractional excretion of solutes have long been considered excellent research tools to investigate tubular physiology, their clinical use has become common over the last 40 years in the diagnoses of many disorders; however, none have reached the clinical utility of the fractional excretion of sodium in the ab...

journal_title：Renal failure

authors： Diskin CJ,Stokes TJ,Dansby LM,Radcliff L,Carter TB

更新日期：2010-01-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection has recently become the major cause of chronic liver disease among patients on chronic hemodialysis. The use of erythropoietin for treatment of anemia has reduced the number of blood transfusions, but the frequency of HCV infection has not declined in hemodialysis units. The exact mod...

journal_title：Renal failure

authors： Harmankaya O,Cetin B,Obek A,Seber E

更新日期：2002-09-01 00:00:00

abstract：AIM:To investigate the therapeutic effects of oral carbonic adsorbent on rats with early-stage renal failure. METHODS:The early-stage renal failure model was established with three-fourth subtotal nephrectomy Wistar rats. Four weeks after the subtotal nephrectomy, the rats were randomly divided into four groups: (1) a...

journal_title：Renal failure

authors： Tan X,He J,Cao X,Zou J,Liu H,Ding X

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:There are few reports on the safety and efficacy of long-term treatment with statins in patients with chronic renal disease and hyperlipidemia. We evaluated these subjects treated with fluvastatin. METHODS:After a 4-week run-in period, a total of 80 patients with diabetic nephropathy or chronic glomerulonep...

journal_title：Renal failure

authors： Yasuda G,Kuji T,Hasegawa K,Ogawa N,Shimura G,Ando D,Umemura S

更新日期：2004-07-01 00:00:00

abstract：:Recently, we demonstrated that furosemide improves renal hemodynamics and attenuates ischemia/reperfusion (I/R)-associated changes in angiogenesis-related gene expression. However, the effect of furosemide on I/R-induced apoptosis is not known. We utilized a rat model of acute ischemic nephropathy to test the hypothes...

journal_title：Renal failure

authors： Aravindan N,Aravindan S,Riedel BJ,Weng HR,Shaw AD

更新日期：2007-01-01 00:00:00

abstract：AIM:The aim of this study was to evaluate the effects of curcumin in an experimental model of busulfan-induced renal toxicity with emphasis on importance of histological alterations. METHODS:In this study, we utilized 32 adult male Wistar rats (250 ± 10 g). All the animals were divided into four experimental groups ra...

journal_title：Renal failure

authors： Abdollahifar MA,Ebrahimi V,Aliaghaei A,Raoofi A,Khosravi A,Hasani A,Mehdizadeh A,Asadi M

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Peritonitis, the most important limitation of peritoneal dialysis (PD), could be detected by biomarkers in dialysate effluent, representing a noninvasive method to indirectly assess the peritoneum status. The aim of our study was to test high mobility group box 1 (HMGB1) in PD patients, evaluating its role a...

journal_title：Renal failure

authors： Chimenz R,Lacquaniti A,Colavita L,Chirico V,Fede C,Buemi M,Fede C

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:There are little data on the incidence of acute renal failure (ARF) from India due to the absence of central registry. The etiology, course, and outcome of ARF differ in various parts of India. Significant trend changes were reported even within a same center over a period of time. AIM:To find out the epide...

journal_title：Renal failure

authors： Jayakumar M,Prabahar MR,Fernando EM,Manorajan R,Venkatraman R,Balaraman V

更新日期：2006-01-01 00:00:00

abstract：:Rat renal cortical mitochondria were isolated from Wistar male rats weighing 80 to 120 g to investigate whether the source of oxygen free radicals was renal cortical mitochondria enhanced by gentamicin. In renal cortical mitochondria with or without the addition of gentamicin, DMSO, DFO, CAT, SOD, and MT1 were added s...

journal_title：Renal failure

authors： Yang CL,Du XH,Han YX

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Influenza infection is a significant cause of morbidity and mortality in general population. Hemodialysis patients are considered at high risk of influenza infection given their altered immune status. Pandemic influenza virus is new for human beings, so it is hard to predict the response to infection or vacc...

journal_title：Renal failure

authors： Temiz G,Kasifoglu N,Kiris A,Ozturk S,Sahin G,Yalcin AU,Us T

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:An increased red blood cell (RBC) phosphatidylserine (PS) exposure in uremic patients was found that could promote macrophage recognition and decrease RBC survival time. Furthermore, a reduced red cell life span was found to contribute anemia in patients with renal failure. It is therefore possible to hypoth...

journal_title：Renal failure

authors： Bi SH,Cheng LT,Wang T

更新日期：2006-01-01 00:00:00

abstract：:In this prospective study, we aimed to determine the protective antioxidant role of alpha-lipoic acid (ALA) on development of contrast-induced nephropathy (CIN) in diabetic patients undergoing coronary angiography. Seventy-eight diabetic patients undergoing coronary angiography were included. Thirty-nine patients were...

journal_title：Renal failure

authors： Cicek M,Yıldırır A,Okyay K,Yazici AC,Aydinalp A,Kanyilmaz S,Muderrisoglu H

更新日期：2013-01-01 00:00:00

abstract：:The necessary exposure of blood to biomembranes during hemodialysis has been viewed by many as an immunogenic challenge leading to an acute phase response. In this study we examined the relationship between hemodialysis-induced immune activation and intradialytic hypotension, using the acute phase reactant serum C-rea...

journal_title：Renal failure

authors： Tomita M,Malhotra D,Dheenan S,Shapiro JI,Henrich WL,Santoro TJ

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:In this study, we compared predialysis and dialysis patients with the controls in terms of insulin resistance and evaluated the association with inflammation that is a risk factor for cardiovascular disease. MATERIALS AND METHODS:A total of 134 non-diabetic patients with controls (n=33), predialysis (n=29) a...

journal_title：Renal failure

authors： Akalın N,Köroğlu M,Harmankaya Ö,Akay H,Kumbasar B

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Gastrointestinal complications are frequent in patients with renal disease and are responsible for substantial morbidity and mortality among these patients in developing countries. Many times, these patients are subjected to endoscopic evaluation and mucosal biopsies are taken for definitive diagnosis. This ...

journal_title：Renal failure

authors： Thomas R,Panackal C,John M,Joshi H,Mathai S,Kattickaran J,Iqbal M

更新日期：2013-01-01 00:00:00

abstract：:Objective: To study the efficacy and safety of sustained low-efficiency diafiltration (SLEDf) versus hemodialysis (HD) for patients with wasp stings who developed stage III acute kidney injury (AKI). Methods: We retrospectively analyzed the clinical data of consecutive patients who developed AKI following wasp stings....

journal_title：Renal failure

authors： Deng YY,Shen JM,Mao YN,Gou R,Li WW,Ye TT

更新日期：2019-11-01 00:00:00

abstract：BACKGROUNDS/AIMS:Renal ischemia-reperfusion (IR) induces organ damage in remote organs. The aim of this study was to assess the role of leukocytes in the induction of liver damage after renal IR injury. METHODS:Inbred mice were subjected to either sham operation or bilateral renal IR injury (60 min ischemia followed b...

journal_title：Renal failure

authors： Khastar H,Kadkhodaee M,Sadeghipour HR,Seifi B,Hadjati J,Delavari F,Soleimani M

更新日期：2011-01-01 00:00:00