Is there an association of hepatitis B virus infection with minimal change disease of nephrotic syndrome? A clinical observational report.

Abstract:

:The rate of hepatitis B virus (HBV) infection is high in the Chinese population, and the implications of HBV infection are widely recognized, and membranous nephropathy is the most common renal lesion to be associated with HBV infection. Minimal change disease (MCD) is one of the most important histopathological characteristics in patients with nephrotic syndrome. There is no any study to report that HBV infection is associated with the etiology of MCD. Herein, we report four MCD patients with HBV infection and speculate that there is an association of HBV infection with the pathological type of MCD. In this study, we also reported the treatment schedule for these four MCD patients, and found that the anti-virus alone and combination of anti-virus with immunosuppressive agent could obtain a benefit for MCD patients with HBV infection. However, a well-designed study should be performed to confirm this association.

journal_name

Ren Fail

journal_title

Renal failure

authors

Zhou TB,Jiang ZP

doi

10.3109/0886022X.2014.1001711

subject

Has Abstract

pub_date

2015-04-01 00:00:00

pages

459-61

issue

3

eissn

0886-022X

issn

1525-6049

journal_volume

37

pub_type

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