Effect of dialysis on erythrocyte membrane of chronically hemodialyzed patients.

Abstract:

:The present work examines the role of uremia and the effect of dialysis treatment on red blood cells (RBCs) membrane properties of hemodialysis patients. The results showed that, the uremic patients had a lower values of erythrocyte deformability than that of healthy control subject. The median osmotic fragility (MOF) showed a significant increase in hemodialyzed patients than that for control group. The osmotic resistance to hemolysis was improved after dialysis. The solubilization process of the RBCs membrane showed that the detergent concentration needed to solubilize the RBCs membrane for uremic patient was much higher than that for control group. The abnormalities of the present results for RBCs membrane properties are mostly related to membrane fluidity, which are slightly improved after dialysis. Biochemical analysis showed a decreasing trend in RBCs count, urea nitrogen, creatinine, potassium,

journal_name

Ren Fail

journal_title

Renal failure

authors

Ibrahim FF,Ghannam MM,Ali FM

doi

10.1081/jdi-120015680

subject

Has Abstract

pub_date

2002-11-01 00:00:00

pages

779-90

issue

6

eissn

0886-022X

issn

1525-6049

journal_volume

24

pub_type

临床试验,杂志文章
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    pub_type: 临床试验,杂志文章,随机对照试验

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