Abstract:
:The present work examines the role of uremia and the effect of dialysis treatment on red blood cells (RBCs) membrane properties of hemodialysis patients. The results showed that, the uremic patients had a lower values of erythrocyte deformability than that of healthy control subject. The median osmotic fragility (MOF) showed a significant increase in hemodialyzed patients than that for control group. The osmotic resistance to hemolysis was improved after dialysis. The solubilization process of the RBCs membrane showed that the detergent concentration needed to solubilize the RBCs membrane for uremic patient was much higher than that for control group. The abnormalities of the present results for RBCs membrane properties are mostly related to membrane fluidity, which are slightly improved after dialysis. Biochemical analysis showed a decreasing trend in RBCs count, urea nitrogen, creatinine, potassium,
journal_name
Ren Failjournal_title
Renal failureauthors
Ibrahim FF,Ghannam MM,Ali FMdoi
10.1081/jdi-120015680subject
Has Abstractpub_date
2002-11-01 00:00:00pages
779-90issue
6eissn
0886-022Xissn
1525-6049journal_volume
24pub_type
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