Primary disseminated form of Ewing sarcoma in association with hypercalcemia and acute renal failure.

Abstract:

:We present a case of an extremely rare form of Ewing sarcoma--primary disseminated, with fulminating course, severe hypercalcemia, extensive calcium deposition in parenchymatous organs, including kidneys, and acute renal failure as a clinical consequence. Correction of hypercalcemia was followed by prompt restoration of the glomerular filtration rate (GFR), suggesting that hypercalcemia had a direct effect on its regulation independent of the renal tubular damage. The effectiveness of the treatment with indomethacin indirectly supports the possibility of prostaglandin-mediated humoral hypercalcemia of malignancy.

journal_name

Ren Fail

journal_title

Renal failure

authors

Lozance LA,Zafirovska KG,Bogdanovska SV,Zafirovski GJ

doi

10.3109/08860229409045083

subject

Has Abstract

pub_date

1994-01-01 00:00:00

pages

525-34

issue

4

eissn

0886-022X

issn

1525-6049

journal_volume

16

pub_type

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