Paced mating behavior in the female rat following lesions of three regions responsive to vaginocervical stimulation.


:The present study examines the effects of ibotenic acid lesions of the medial amygdala, the bed nucleus of the stria terminalis and the medial preoptic area on the display of paced mating behavior in female rats. Lesions of either the medial amygdala or the bed nucleus of the stria terminalis have no effect on the display of paced mating behaviors in ovariectomized, hormone-primed rats. In contrast, lesions of the medial preoptic area significantly lengthen contact-return latencies following intromissions and ejaculations and increase withdrawal from the male following intromissions. The present study demonstrates that the medial amygdala and the bed nucleus of the stria terminalis are not involved in the behavioral responses accompanying paced mating behavior, whereas the medial preoptic area is a critical component of the neural circuit mediating paced mating behavior as well as other appetitive aspects of mating.


Brain Res


Brain research


Guarraci FA,Megroz AB,Clark AS




Has Abstract


2004-02-27 00:00:00














  • Short-latency excitation of phrenic motor output mediated by non-NMDA receptors.

    abstract::This study tested the hypothesis that the short-latency excitation of the phrenic motor output elicited by superior laryngeal nerve (SLN) stimulation requires non-NMDA receptor-mediated neurotransmission in the region of the dorsal respiratory group (DRG) of the adult cat. Injection of the non-NMDA receptor antagonist...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Karius DR,Speck DF

    更新日期:1995-06-05 00:00:00

  • Inhibition of GSK-3beta mediates expression of MMP-9 through ERK1/2 activation and translocation of NF-kappaB in rat primary astrocyte.

    abstract::Glycogen synthase kinase (GSK)-3beta and extracellular signal-regulated kinase (ERK) regulate several cellular signaling pathways in common, including embryonic development, cell differentiation and apoptosis. In this study, we investigated whether GSK-3beta inhibition is involved in ERK activation, which affects the ...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Kim SD,Yang SI,Kim HC,Shin CY,Ko KH

    更新日期:2007-12-01 00:00:00

  • Ontogenesis of muscarinic receptors in cultured rat hippocampal cells.

    abstract::The ontogeny of muscarinic cholinergic receptors was studied in primary cultures of dissociated rat hippocampal cells. The specific [3H]quinuclidinyl benzilate [( 3H]QNB) to intact cells was detected after two days in culture. Scatchard analysis revealed only a unique binding site at all of the days tested, with a ver...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Fernandez-Tomé P,Segal M

    更新日期:1987-09-01 00:00:00

  • Potential use of DPCPX as probe for in vivo localization of brain A1 adenosine receptors.

    abstract::The suitability of (3H)DPCPX (8-cyclopentyl-1,3-dipropylxanthine), a xanthine derivative, as an vivo probe for labelling adenosine A1 receptors was studied in rats. [3H]DPCPX (nM) penetrated largely into the brain (0.8% of the injected dose per gram of brain tissue 5 min after injection). Brain concentrations stayed a...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Bisserbe JC,Pascal O,Deckert J,Mazière B

    更新日期:1992-12-18 00:00:00

  • Genetic influences on electrical seizure threshold.

    abstract::C57BL/6J (B6) and DBA/2J (D2) mice have been characterized previously as seizure-resistant and seizure-sensitive, respectively, a distinction based primarily upon a differential response to the convulsant effects of various drugs. In the present study, electroconvulsive shock (ECS) was used to assess maximal electrosh...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Ferraro TN,Golden GT,Snyder R,Laibinis M,Smith GG,Buono RJ,Berrettini WH

    更新日期:1998-11-30 00:00:00

  • Blood-brain barrier permeability to horseradish peroxidase in twitcher and cuprizone-intoxicated mice.

    abstract::The status of blood-brain barrier (BBB) permeability was investigated in the twitcher, an authentic murine model of globoid cell leukodystrophy (GLD, Krabbe disease) and cuprizone-intoxicated mice. Although extensive demyelination was noted in the CNS of both mice and additionally, macrophage infiltration was pronounc...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Kondo A,Nakano T,Suzuki K

    更新日期:1987-11-03 00:00:00

  • The neurotensinergic synaptic innervation of vasopressin containing neurons in the rat hypothalamic paraventricular nucleus.

    abstract::A recent physiological report suggested that neurotensin could inhibit the vasopressin releasing from vasopressin-producing neurons in the hypothalamic paraventricular nucleus but not in the supraoptic nucleus. In the present study, the synaptic relationship between the neurotensin-like immunoreactive and vasopressin-...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Wang QP,Guan JL,Ochiai H,Nakai Y

    更新日期:1999-07-10 00:00:00

  • Receptor blockade reveals a correspondence between hippocampal-dependent behavior and experience-dependent synaptic enhancement.

    abstract::This study examined the involvement of N-methyl-D-aspartate receptors (NMDARs) in experience-dependent synaptic plasticity. Rats chronically received an NMDA receptor antagonist (AP5) or saline (SAL) and were exposed to individual cages (IC) or environmental enrichment (EC). AP5 impaired measures of hippocampal-depend...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Foster TC,Fugger HN,Cunningham SG

    更新日期:2000-07-14 00:00:00

  • Ischemic preconditioning reduces infarct volume after subdural hematoma in the rat.

    abstract::The aim of the present study was to investigate the effects of ischemic preconditioning on infarct volume in a rat model of subdural hematoma (SDH). Ischemic preconditioning was induced by 15 min transient middle cerebral artery (MCA) occlusion followed 3 days later by the injection of 300 microl of autologous venous ...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Mackay KB,Stiefel TH,Foster AC

    更新日期:2002-03-15 00:00:00

  • Losartan, nonpeptide angiotensin II-type 1 (AT1) receptor antagonist, attenuates pressor and sympathoexcitatory responses evoked by angiotensin II and L-glutamate in rostral ventrolateral medulla.

    abstract::We investigated the effect of losartan, a nonpeptide angiotensin II (Ang II)-type 1 (AT1) receptor antagonist, on the responses evoked by Ang II and L-glutamate (L-Glu) in the rostral ventrolateral medulla (RVLM). Adult spontaneously hypertensive rats (SHR) and Wistar-Kyoto (WKY) rats were anesthetized with halothane ...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Averill DB,Tsuchihashi T,Khosla MC,Ferrario CM

    更新日期:1994-12-05 00:00:00

  • Localizing the corticospinal neurons in neonatal, developing and mature albino rat.

    abstract::Following the administration of horseradish peroxidase (HRP) in the middle or lower cervical cord segments of neonatal (1-10 days), developing (15-20 days) and mature (2-4 months) albino rats, labeled pyramidal neurons were found in layer V of the cerebral cortex. They formed one continuous band of labeled neurons in ...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Leong SK

    更新日期:1983-04-11 00:00:00

  • Characteristics of a Ca2+/calmodulin-dependent binding of the Ca2+ channel antagonist, nitrendipine, to a postsynaptic density fraction isolated from canine cerebral cortex.

    abstract::Synaptic membrane (SM) and postsynaptic density (PSD) fractions isolated from the cerebral cortex (CTX) and cerebellum (CL) of the canine brain were found to contain one class of specific nitrendipine binding sites. The specific binding constants were: CTX-SM, Kd = 110 pM (Bmax = 126 fmol/mg protein); CTX-PSD, Kd = 20...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Wu K,Sachs L,Carlin RK,Siekevitz P

    更新日期:1986-11-01 00:00:00

  • Supersensitivity of analgesic responses to alpha 2-adrenergic agonists in genetically hypertensive rats.

    abstract::This study compared the responsivity of alpha 2-adrenoceptors to agonists in normotensive (WKY) and genetically hypertensive (SH) rats. Clonidine produced a greater degree of analgesia in SH as compared to WKY rats. This analgesia was antagonized by yohimbine. Neither naphazoline nor 4-hydroxy-clonidine produced analg...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Marwaha J

    更新日期:1984-06-25 00:00:00

  • No evidence of brain cell degeneration after long-term sleep deprivation in rats.

    abstract::Sleep deprivation leads to cognitive impairments in humans and, if sustained for 2-3 weeks in rats, it is invariably fatal. It has been suggested that neural activity associated with waking, if it is not interrupted by periods of sleep, may damage brain cells through excitotoxic or oxidative mechanisms and eventually ...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Cirelli C,Shaw PJ,Rechtschaffen A,Tononi G

    更新日期:1999-09-04 00:00:00

  • Increased [3H]glutamate receptor binding in aged rats.

    abstract::Na-independent [3H]glutamate binding to rat hippocampal membranes increases progressively as a function of age. The increased binding represents an increased number of binding sites without changes in their apparent affinity for glutamate. However, [3H]glutamate binding, measured with a saturating concentration of cal...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Baudry M,Arst DS,Lynch G

    更新日期:1981-10-26 00:00:00

  • Amelioration of ischemic spinal cord damage by postischemic treatment with propentofylline (HWA 285).

    abstract::The effect of the xanthine derivative propentofylline (HWA 285) on metabolic and functional recovery in rabbit spinal cord after 20 and 30 min ischemia and 4 days of reperfusion was investigated. Pre-treatment with 20 mg/kg significantly improved recovery of the energy state in the spinal cord, however, without signif...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Danielisová V,Chavko M

    更新日期:1992-09-11 00:00:00

  • Autoradiographic analysis of dopamine receptor-stimulated [(35)S]GTPgammaS binding in rat striatum.

    abstract::Autoradiographic analysis of [(35)S]GTPgammaS binding was used to investigate functional activation of dopamine receptors in rat striatum. Dopamine-stimulated [(35)S]GTPgammaS binding was observed with a maximal increase of 38% over basal activity. A similar stimulatory response was obtained with the D(2) agonist quin...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: He L,Di Monte DA,Langston JW,Quik M

    更新日期:2000-12-01 00:00:00

  • Neuroprotection and immunomodulation in the gut of parkinsonian mice with a plasmalogen precursor.

    abstract::Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide. It is typically associated with motor symptoms originating from the degeneration of nigrostriatal dopamine (DA) neurons. Early stages of PD have been associated with an alteration in DA production in intestinal DAergic neurons alon...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Nadeau J,Smith T,Lamontagne-Proulx J,Bourque M,Al Sweidi S,Jayasinghe D,Ritchie S,Di Paolo T,Soulet D

    更新日期:2019-12-15 00:00:00

  • Participation of Rel/NF-kappaB transcription factors in long-term memory in the crab Chasmagnathus.

    abstract::The induction of gene expression has been correlated with long-lasting neuronal plasticity and long-term memory (LTM) formation. The fast activation of constitutive transcription factors by signaling mechanisms is thought to be the link between synaptic events and gene expression. However, only one constitutive transc...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Freudenthal R,Romano A

    更新日期:2000-02-14 00:00:00

  • Distribution of the ganglioside GD3 in the human nervous system detected by R24 mouse monoclonal antibody.

    abstract::Immunohistochemical staining with mouse monoclonal antibody R24 recognizing the ganglioside GD3 was used to study the distribution of GD3 in the human brain. Positive staining was primarily found in the surrounding neuropil of many neuronal groups in the brainstem and spinal cord, cerebellum, retina and dentate gyrus ...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Graus F,Cordon-Cardo C,Houghton AN,Melamed MR,Old LJ

    更新日期:1984-12-17 00:00:00

  • Signalling events regulating the retrograde axonal transport of 125I-beta nerve growth factor in vivo.

    abstract::The molecular mechanisms regulating the retrograde axonal transport of nerve growth factor (NGF) are currently unknown. This study identifies some of the signalling events involved. The phosphoinositide 3-kinase (PI3-kinase) inhibitor wortmannin (1 nmol/eye) irreversibly inhibits the amount of 125I-betaNGF retrogradel...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Reynolds AJ,Bartlett SE,Hendry IA

    更新日期:1998-07-06 00:00:00

  • Modulation of nerve membrane sodium channel activation by deltamethrin.

    abstract::Deltamethrin is a highly potent pyrethroid insecticide that causes hypersensitivity, choreoathetosis, tremors, and paralysis in mammals. It is known to modify the sodium channel in such a way as to prolong the tail current associated with step repolarization following a depolarizing pulse. Using the axial-wire voltage...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Brown LD,Narahashi T

    更新日期:1992-07-03 00:00:00

  • Potency ratios of morphine and morphine-6beta-glucuronide analgesia elicited from the periaqueductal gray, locus coeruleus or rostral ventromedial medulla of rats.

    abstract::The present study examined whether morphine and morphine-6beta-glucuronide (M6G) analgesia on the tail-flick and jump tests differed in potency in the periaqueductal gray, the locus coeruleus or the rostral ventromedial medulla. Morphine and M6G significantly and dose-dependently elicited analgesia on both nociceptive...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Krzanowska EK,Rossi GC,Pasternak GW,Bodnar RJ

    更新日期:1998-07-20 00:00:00

  • Regulation of AQP4 protein expression in rat brain astrocytes: role of P2X7 receptor activation.

    abstract::ATP has been recognized as an important extracellular signaling molecule and P2X receptors are membrane ion channels activated by the binding of extracellular ATP. Since both AQP4 and P2X7 receptor (P2X7R) are known to be present in astrocytes, we examined whether P2X7R activation plays a role in the regulation of AQP...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Lee M,Lee SJ,Choi HJ,Jung YW,Frøkiaer J,Nielsen S,Kwon TH

    更新日期:2008-02-21 00:00:00

  • Delayed kindling epileptogenesis and increased neurogenesis in adult rats housed in an enriched environment.

    abstract::Environmental risk factors such as stressful experiences have long been recognized to affect seizure susceptibility, but little attention has been paid to the potential effects of improving housing conditions. In this study, we investigated the influence of an enriched environment on epileptogenesis. Epileptic suscept...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Auvergne R,Leré C,El Bahh B,Arthaud S,Lespinet V,Rougier A,Le Gal La Salle G

    更新日期:2002-11-08 00:00:00

  • Further evidence for a central reorganisation of synaptic connectivity in patients with hypoglossal-facial anastomosis in man.

    abstract::In normal subjects, electrical stimulation of trigeminal mucosal afferents (lingual nerve - V3) can elicit a short latency (12.5+/-0. 3 ms; mean+/-S.D.) reflex response in the ipsilateral genioglossus muscle (Maisonobe et al., Reflexes elicited from cutaneous and mucosal trigeminal afferents in normal human subjects. ...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Tankéré F,Maisonobe T,Naccache L,Lamas G,Soudant J,Danziger N,Bouche P,Fournier E,Willer JC

    更新日期:2000-05-02 00:00:00

  • Effect of gamma-hydroxybutyrate and its antagonist NCS-382 on spontaneous cell firing in the prefrontal cortex of the rat.

    abstract::Gamma-hydroxybutyrate (GHB) at low doses (5-10 mg/kg i.p.) increased and at high doses (160-320 mg/kg i.p.) decreased the spontaneous firing rate of prefrontal cortex (PFC) neurons recorded in urethane-anesthetized rats. Only excitations were blocked by NCS-382, a specific GHB receptor antagonist; this suggests that t...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Godbout R,Jelenic P,Labrie C,Schmitt M,Bourguignon JJ

    更新日期:1995-02-27 00:00:00

  • Activation of cell-survival signal Akt by GDNF in normal rat brain.

    abstract::Glial cell line-derived neurotrophic factor (GDNF) activates protein kinase Akt/PKB by phosphorylation (p-Akt) which plays key roles in cell survival. In the current study, we investigated a temporal expression of p-Akt by immunohistochemical analysis after a topical application of GDNF to normal cerebral hemisphere o...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Jin G,Omori N,Li F,Sato K,Nagano I,Manabe Y,Shoji M,Abe K

    更新日期:2002-12-27 00:00:00

  • Stem cells distribution, cellular proliferation and migration in the adult Austrolebias charrua brain.

    abstract::Our previous studies demonstrated that Austrolebias charrua annual fish is an excellent model to study adult brain cell proliferation and neurogenesis due to the presence of active and fast neurogenesis in several regions during its short lifespan. Our main goal was to identify and localize the cells that compose the ...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Torres-Pérez M,Rosillo JC,Berrosteguieta I,Olivera-Bravo S,Casanova G,García-Verdugo JM,Fernández AS

    更新日期:2017-10-15 00:00:00

  • Involvement of bulbospinal pathways in the antinociceptive effect of clomipramine in the rat.

    abstract::The involvement of bulbospinal pathways in the antinociceptive effect of clomipramine in experimental pain was studied. The antinociceptive effect of the antidepressant (0.5 mg/kg), intravenously injected, was evaluated after a unilateral lesion of the dorsolateral funiculus. The results showed that this effect was su...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Ardid D,Jourdan D,Mestre C,Villanueva L,Le Bars D,Eschalier A

    更新日期:1995-10-16 00:00:00